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Molecular isothermal techniques for combating infectious diseases: towards low-cost point-of-care diagnostics

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Gilberto Silva Nunes Bezerra, Walter Lins Barbosa Júnior, Amanda Virgínia Batista Vieira, Amanda Tavares Xavier, Manoel Sebastião Da Costa Lima Júnior, Edeneide Maria Xavier, Elis Dionísio Da Silva, Nilma Cintra Leal & Zulma Maria De Medeiros. (2020) Loop-mediated isothermal amplification methods for diagnosis of visceral leishmaniasis (kala-azar) – a systematic review. Expert Review of Molecular Diagnostics 20:5, pages 455-465.
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Luc Bissonnette & Michel G. Bergeron. (2017) Portable devices and mobile instruments for infectious diseases point-of-care testing. Expert Review of Molecular Diagnostics 17:5, pages 471-494.
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Susanne B. Haga. (2016) Challenges of development and implementation of point of care pharmacogenetic testing. Expert Review of Molecular Diagnostics 16:9, pages 949-960.
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Pedro Brotons, Hector D de Paz, Cristina Esteva, Irene Latorre & Carmen Muñoz-Almagro. (2016) Validation of a loop-mediated isothermal amplification assay for rapid diagnosis of pertussis infection in nasopharyngeal samples. Expert Review of Molecular Diagnostics 16:1, pages 125-130.
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Ameh James & Joanne Macdonald. (2015) Recombinase polymerase amplification: Emergence as a critical molecular technology for rapid, low-resource diagnostics. Expert Review of Molecular Diagnostics 15:11, pages 1475-1489.
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Articles from other publishers (60)

Defne Yigci, Nazente Atçeken, Ali K. Yetisen & Savas Tasoglu. (2023) Loop-Mediated Isothermal Amplification-Integrated CRISPR Methods for Infectious Disease Diagnosis at Point of Care. ACS Omega 8:46, pages 43357-43373.
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Kunlun Jiang, Jung-Hoon Lee, To Sing Fung, Jingrui Wu, Congnuan Liu, Hua Mi, R.P.V. Jayanthe Rajapakse, Udeni B.R. Balasuriya, Yung-Kang Peng & Yun Young Go. (2023) Next-generation diagnostic test for dengue virus detection using an ultrafast plasmonic colorimetric RT-PCR strategy. Analytica Chimica Acta 1274, pages 341565.
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Abudushalamu Gulinaizhaer, Mingyuan Zou, Shuo Ma, Yuming Yao, Xiaobo Fan & Guoqiu Wu. (2023) Isothermal nucleic acid amplification technology in HIV detection. The Analyst 148:6, pages 1189-1208.
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Bahareh Maleki & Zohreh Hojati. (2022) A precise review on NAATs ‐based diagnostic assays for COVID ‐19: A motion in fast POC molecular tests . European Journal of Clinical Investigation 52:11.
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Chih-Yu Chen, Hung-Wei Yang, Ping-Han Hsieh, Chia-Hsun Hsieh & Min-Hsien Wu. (2022) Development of a photothermal bead-based nucleic acid amplification test (pbbNAAT) technique for a high-performance loop-mediated isothermal amplification (LAMP)–based point-of-care test (POCT). Biosensors and Bioelectronics 215, pages 114574.
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Sheng Ding, Yinghua Wei, Juan Dong, Feng Du, Xin Cui & Zhuo Tang. (2022) All-in-one multiplex isothermal reaction combining miniaturized device enables rapid screening of infected samples. Sensors and Actuators B: Chemical 368, pages 132226.
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Yajuan Dong, Yongjuan Zhao, Shenwei Li, Zhenzhou Wan, Renfei Lu, Xianguang Yang, Guoying Yu, Julien Reboud, Jonathan M. Cooper, Zhengan Tian & Chiyu Zhang. (2022) Multiplex, Real-Time, Point-of-care RT-LAMP for SARS-CoV-2 Detection Using the HFman Probe. ACS Sensors 7:3, pages 730-739.
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Mahdi Naseri, Zyta M Ziora, George P Simon & Warren Batchelor. (2021) ASSURED‐compliant point‐of‐care diagnostics for the detection of human viral infections. Reviews in Medical Virology 32:2.
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Eunjung Kim, Eun‐Kyung Lim, Geunseon Park, Chaewon Park, Jong‐Woo Lim, Hyo Lee, Woonsung Na, Minjoo Yeom, Jinyoung Kim, Daesub Song & Seungjoo Haam. (2021) Advanced Nanomaterials for Preparedness Against (Re‐)Emerging Viral Diseases. Advanced Materials 33:47, pages 2005927.
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Beatriz B. Oliveira, Bruno Veigas & Pedro Viana Baptista. (2021) Isothermal Amplification of Nucleic Acids: The Race for the Next “Gold Standard”. Frontiers in Sensors 2.
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Guozhen Tian, Decai Zhang, Yuexin Wang, Tingwei Hu, Yingzi Lin, Yongxia Wang, Wei Cheng & Qianfeng Xia. (2021) A universal CRISPR/Cas12a nucleic acid sensing platform based on proximity extension and transcription-unleashed self-supply crRNA. Analytica Chimica Acta 1176, pages 338755.
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Yingxue Li, Xin Chen, Yongjuan Zhao, Zhenzhou Wan, Yi Zeng, Yingying Ma, Lianqun Zhou, Gaolian Xu, Julien Reboud, Jonathan M. Cooper & Chiyu Zhang. (2021) A rapid variant-tolerant reverse transcription loop-mediated isothermal amplification assay for the point of care detection of HIV-1. The Analyst 146:17, pages 5347-5356.
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Sanchita Bhadra, Timothy E. Riedel, Simren Lakhotia, Nicholas D. Tran & Andrew D. Ellington. (2021) High-Surety Isothermal Amplification and Detection of SARS-CoV-2. mSphere 6:3.
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Adriana Larrea-Sarmiento, James P. Stack, Anne M. Alvarez & Mohammad Arif. (2021) Multiplex recombinase polymerase amplification assay developed using unique genomic regions for rapid on-site detection of genus Clavibacter and C. nebraskensis. Scientific Reports 11:1.
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Supriya Yadav, Niti Nipun Sharma & Jamil Akhtar. (2021) Nucleic acid analysis on paper substrates (NAAPs): an innovative tool for Point of Care (POC) infectious disease diagnosis. The Analyst 146:11, pages 3422-3439.
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Haixia Shi, Jingjie Cui, Husseini Sulemana, Wunian Wang & Li Gao. (2021) Protein detection based on rolling circle amplification sensors. Luminescence 36:4, pages 842-848.
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Jafar Ali, Saira Elahi, Asghar Ali, Hassan Waseem, Rameesha Abid & Mohamed Mohamed. (2021) Unveiling the Potential Role of Nanozymes in Combating the COVID-19 Outbreak. Nanomaterials 11:5, pages 1328.
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Dhananjay Kumar, Rajiv Ranjan Kumar, Preeti Rana, S. K. Mendiratta, R. K. Agarwal, Praveen Singh, Sarita Kumari & Jyoti Jawla. (2020) On point identification of species origin of food animals by recombinase polymerase amplification-lateral flow (RPA-LF) assay targeting mitochondrial gene sequences. Journal of Food Science and Technology 58:4, pages 1286-1294.
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Zheng Zhang, Yongxiang Yu, Jing Chen, Yingeng Wang, Yong Jiang, Meijie Liao, Xiaojun Rong & Hao Zhang. (2021) Development of a Microfluidics-Based Quantitative Real-Time PCR to Rapidly Identify Photobacterium damselae subsp. damselae with Different Pathogenicity by Detecting the Presence of mcp or dly Gene. Journal of Ocean University of China 20:2, pages 445-453.
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Thanyarat Chaibun, Jiratchaya Puenpa, Tatchanun Ngamdee, Nimaradee Boonapatcharoen, Pornpat Athamanolap, Anthony Peter O’Mullane, Sompong Vongpunsawad, Yong Poovorawan, Su Yin Lee & Benchaporn Lertanantawong. (2021) Rapid electrochemical detection of coronavirus SARS-CoV-2. Nature Communications 12:1.
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Martin Faye, Ahmed Abd El Wahed, Oumar Faye, Jonas Kissenkötter, Bernd Hoffmann, Amadou Alpha Sall & Ousmane Faye. (2021) A recombinase polymerase amplification assay for rapid detection of rabies virus. Scientific Reports 11:1.
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Jongmin Kim & Yong-Ak Song. 2021. Paper-Based Medical Diagnostic Devices. Paper-Based Medical Diagnostic Devices 87 113 .
Mohamed El-Tholoth, Michael G. Mauk, Yasser F. Elnaker, Samah M. Mosad, Amin Tahoun, Mohamed W. El-Sherif, Maha S. Lokman, Rami B. Kassab, Ahmed Abdelsadik, Ayman A. Saleh & Ehab Kotb Elmahallawy. (2020) Molecular Characterization and Developing a Point-of-Need Molecular Test for Diagnosis of Bovine Papillomavirus (BPV) Type 1 in Cattle from Egypt. Animals 10:10, pages 1929.
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Patrycja Zalas-WięcekEugenia Gospodarek-KomkowskaAgata Smalczewska. (2020) Rapid Detection of Genes Encoding Extended-Spectrum Beta-Lactamase and Carbapenemase in Clinical Escherichia coli Isolates with eazyplex SuperBug CRE System . Microbial Drug Resistance 26:10, pages 1245-1249.
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Ameh James & John Alawneh. (2020) COVID-19 Infection Diagnosis: Potential Impact of Isothermal Amplification Technology to Reduce Community Transmission of SARS-CoV-2. Diagnostics 10:6, pages 399.
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Yong Yang, Yong Chen, Hao Tang, Nan Zong & Xingyu Jiang. (2020) Microfluidics for Biomedical Analysis. Small Methods 4:4, pages 1900451.
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Héctor David de Paz, Pedro Brotons, Cristina Esteva & Carmen Muñoz-Almagro. (2020) Validation of a Loop-Mediated Isothermal Amplification Assay for Rapid Diagnosis of Invasive Pneumococcal Disease. Frontiers in Cellular and Infection Microbiology 10.
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Zeng Li, Joar Esteban Pinto Torres, Julie Goossens, Benoit Stijlemans, Yann G.-J. Sterckx & Stefan Magez. (2020) Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections. PLOS Neglected Tropical Diseases 14:2, pages e0008044.
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Hua Liu, Jinbin Wang, Peng Li, Lan Bai, Junwei Jia, Aihu Pan, Xuanqi Long, Weidong Cui & Xueming Tang. (2020) Rapid detection of P–35S and T-nos in genetically modified organisms by recombinase polymerase amplification combined with a lateral flow strip. Food Control 107, pages 106775.
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Yvonne Piotrowski, Man Kumari Gurung & Atle Noralf Larsen. (2019) Characterization and engineering of a DNA polymerase reveals a single amino-acid substitution in the fingers subdomain to increase strand-displacement activity of A-family prokaryotic DNA polymerases. BMC Molecular and Cell Biology 20:1.
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Than Linh Quyen, Steen Nordentoft, Aaydha Chidambara Vinayaka, Tien Anh Ngo, Pia Engelsmenn, Yi Sun, Mogens Madsen, Dang Duong Bang & Anders Wolff. (2019) A Sensitive, Specific and Simple Loop Mediated Isothermal Amplification Method for Rapid Detection of Campylobacter spp. in Broiler Production. Frontiers in Microbiology 10.
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Than Linh Quyen, Tien Anh Ngo, Dang Duong Bang, Mogens Madsen & Anders Wolff. (2019) Classification of Multiple DNA Dyes Based on Inhibition Effects on Real-Time Loop-Mediated Isothermal Amplification (LAMP): Prospect for Point of Care Setting. Frontiers in Microbiology 10.
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Jia Li, Nina M. Pollak & Joanne Macdonald. (2019) Multiplex Detection of Nucleic Acids Using Recombinase Polymerase Amplification and a Molecular Colorimetric 7-Segment Display. ACS Omega 4:7, pages 11388-11396.
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Yi Zhou, Zhenzhou Wan, Shuting Yang, Yingxue Li, Min Li, Binghui Wang, Yihong Hu, Xueshan Xia, Xia Jin, Na Yu & Chiyu Zhang. (2019) A Mismatch-Tolerant Reverse Transcription Loop-Mediated Isothermal Amplification Method and Its Application on Simultaneous Detection of All Four Serotype of Dengue Viruses. Frontiers in Microbiology 10.
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Jianhu Pang, Qiong Wang, Yuejun Fei, Peng Zhu, Longliang Qiao, Hailong Huang, Chenyang Dang & Weifang Gao. (2019) A real-time recombinase polymerase amplification assay for the rapid detection of Vibrio harveyi. Molecular and Cellular Probes 44, pages 8-13.
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Apoorva Saxena, Vijai Pal, Nagesh Kumar Tripathi & Ajay Kumar Goel. (2019) Development of a rapid and sensitive recombinase polymerase amplification‐lateral flow assay for detection of Burkholderia mallei . Transboundary and Emerging Diseases 66:2, pages 1016-1022.
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Susanna Nybond, Pedro Réu, Samuel Rhedin, Gustav Svedberg, Tobias Alfvén, Jesper Gantelius & Helene Andersson Svahn. (2018) Adenoviral detection by recombinase polymerase amplification and vertical flow paper microarray. Analytical and Bioanalytical Chemistry 411:4, pages 813-822.
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Yingxue Li, Yi Zhou, Yingying Ma, Rong Xu, Xia Jin & Chiyu Zhang. (2019) A Mismatch-tolerant RT-LAMP Method for Molecular Diagnosis of Highly Variable Viruses. BIO-PROTOCOL 9:21.
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Sanchita Bhadra, Timothy E. Riedel, Miguel A. Saldaña, Shivanand Hegde, Nicole Pederson, Grant L. Hughes & Andrew D. Ellington. (2018) Direct nucleic acid analysis of mosquitoes for high fidelity species identification and detection of Wolbachia using a cellphone. PLOS Neglected Tropical Diseases 12:8, pages e0006671.
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Qianru YangKelly J. DomesleBeilei Ge. (2018) Loop-Mediated Isothermal Amplification for Salmonella Detection in Food and Feed: Current Applications and Future Directions . Foodborne Pathogens and Disease 15:6, pages 309-331.
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Bhushan J. Toley, Debayan Das, Ketan A. Ganar, Navjot Kaur, Mithlesh Meena, Dharitri Rath, N. Sathishkumar & Shruti Soni. (2018) Multidimensional Paper Networks: A New Generation of Low-Cost Pump-Free Microfluidic Devices. Journal of the Indian Institute of Science 98:2, pages 103-136.
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Yu Sherry Jiang, Timothy E. Riedel, Jessica A. Popoola, Barrett R. Morrow, Sheng Cai, Andrew D. Ellington & Sanchita Bhadra. (2018) Portable platform for rapid in-field identification of human fecal pollution in water. Water Research 131, pages 186-195.
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Olena Mayboroda, Ioanis Katakis & Ciara K. O'Sullivan. (2018) Multiplexed isothermal nucleic acid amplification. Analytical Biochemistry 545, pages 20-30.
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Navjot Kaur & Bhushan J. Toley. (2018) Paper-based nucleic acid amplification tests for point-of-care diagnostics. The Analyst 143:10, pages 2213-2234.
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Chunxiao Hu, Sumit Kalsi, Ioannis Zeimpekis, Kai Sun, Peter Ashburn, Carrie Turner, J. Mark Sutton & Hywel Morgan. (2017) Ultra-fast electronic detection of antimicrobial resistance genes using isothermal amplification and Thin Film Transistor sensors. Biosensors and Bioelectronics 96, pages 281-287.
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Jane Ru Choi, Kar Wey Yong, Ruihua Tang, Yan Gong, Ting Wen, Fei Li, Belinda Pingguan-Murphy, Dan Bai & Feng Xu. (2017) Advances and challenges of fully integrated paper-based point-of-care nucleic acid testing. TrAC Trends in Analytical Chemistry 93, pages 37-50.
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