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Editorial

The potential of whole genome NGS for infectious disease diagnosis

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Jingying Xu, Qian Huang, Jianhua Yu, Shourong Liu, Zongxing Yang, Fei Wang, Yue Shi, Er Li, Zhaoyi Li & Yunlei Xiao. (2022) Metagenomic Next-Generation Sequencing for the Diagnosis of Suspected Opportunistic Infections in People Living with HIV. Infection and Drug Resistance 15, pages 1767-1775.
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Lluís Moragues-Solanas, Riccardo Scotti & Justin O’Grady. (2021) Rapid metagenomics for diagnosis of bloodstream and respiratory tract nosocomial infections: current status and future prospects. Expert Review of Molecular Diagnostics 21:4, pages 371-380.
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Articles from other publishers (36)

Jinxiang Hao, Weili Li, Yaoyao Wang, Jiangman Zhao & Yu Chen. (2023) Clinical utility of metagenomic next-generation sequencing in pathogen detection for lower respiratory tract infections and impact on clinical outcomes in southernmost China. Frontiers in Cellular and Infection Microbiology 13.
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Wentao Lin, Faqin Xie, Xinan Li, Ruobing Yang, Junan Lu, Zheng Ruan, Dingqiang Ou & Zhiyun Wang. (2023) Diagnostic performance of metagenomic next-generation sequencing and conventional microbial culture for spinal infection: a retrospective comparative study. European Spine Journal 32:12, pages 4238-4245.
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Tao Huang, Rui Zhang & Jinming Li. (2023) CRISPR-Cas-based techniques for pathogen detection: Retrospect, recent advances, and future perspectives. Journal of Advanced Research 50, pages 69-82.
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Sriram Kalpana, Wan-Ying Lin, Yu-Chiang Wang, Yiwen Fu, Amrutha Lakshmi & Hsin-Yao Wang. (2023) Antibiotic Resistance Diagnosis in ESKAPE Pathogens—A Review on Proteomic Perspective. Diagnostics 13:6, pages 1014.
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Muhammad Saeed, Zainab Jamil, Tayyab Shehzad, Syed Zia ul Hasan, Riffat Bibi, Safia Naureen Malik, Hafiz Matee-ur-Rehman & Raees Ahmed. (2023) Role of Next Generation Sequencing (NGS) in Plant Disease Management: A Review. Journal of Applied Research in Plant Sciences 4:01, pages 512-517.
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Kyle Parker, Hillary Wood, Joseph A. Russell, David Yarmosh, Alan Shteyman, John Bagnoli, Brittany Knight, Jacob R. Aspinwall, Jonathan Jacobs, Kristine Werking & Richard Winegar. (2023) Development and Optimization of an Unbiased, Metagenomics-Based Pathogen Detection Workflow for Infectious Disease and Biosurveillance Applications. Tropical Medicine and Infectious Disease 8:2, pages 121.
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Lucas G. Huggins, Anson V. Koehler, Robin B. Gasser & Rebecca J. Traub. 2023. 1 85 .
Changjun Zhu, Minjie Lv, Jianling Huang, Changwen Zhang, Lixu Xie, Tianming Gao, Bo Han, Wenjing Wang & Ganzhu Feng. (2022) Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report. BMC Infectious Diseases 22:1.
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Donghui Zhang, Shujing Chen, Ying Wang, Dongni Hou, Cuicui Chen, Linlin Wang, Xinjun Tang, Xiaoyan Chen, Lin Tong, Yuye Zhang, Jinjun Jiang & Yuanlin Song. (2022) The evaluation of next‐generation sequencing assisted pathogenic detection in immunocompromised hosts with pulmonary infection: A retrospective study. The Clinical Respiratory Journal 16:12, pages 793-801.
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Simon H. Tausch, Tobias P. Loka, Jakob M. Schulze, Andreas Andrusch, Jeanette Klenner, Piotr Wojciech Dabrowski, Martin S. Lindner, Andreas Nitsche & Bernhard Y. Renard. (2022) PathoLive—Real-Time Pathogen Identification from Metagenomic Illumina Datasets. Life 12:9, pages 1345.
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Ramachandran Chelliah, Eric Banan-MwineDaliri, Imran Khan, Shuai Wei, Fazle Elahi, Su-Jung Yeon, Vijayalakshmi Selvakumar, Fred Kwame Ofosu, Momna Rubab, Hum Hun Ju, Harikrishna Reddy Rallabandi, Inamul Hasan Madar, Ghazala Sultan & Deog Hwan Oh. (2022) A review on the application of bioinformatics tools in food microbiome studies. Briefings in Bioinformatics 23:2.
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Dongkai Li, Wei Gai, Jiahui Zhang, Wei Cheng, Na Cui & Hao Wang. (2022) Metagenomic Next-Generation Sequencing for the Microbiological Diagnosis of Abdominal Sepsis Patients. Frontiers in Microbiology 13.
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Qian Li, Wenhua Huang, Shengwei Zhang, Yuling Zheng, Qingyu Lv, Decong Kong, Lei Zhang, Yan Zhang, Zhihu Zhao, Miaoyu Wang, Hua Jiang, Peng Liu & Yongqiang Jiang. (2022) Target-enriched sequencing enables accurate identification of bloodstream infections in whole blood. Journal of Microbiological Methods 192, pages 106391.
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Godagama Gamaarachchige Dinesh Suminda, Srishti Bhandari, Yoonkyung Won, Umesh Goutam, Krishna Kanth Pulicherla, Young-Ok Son & Mrinmoy Ghosh. (2022) High-throughput sequencing technologies in the detection of livestock pathogens, diagnosis, and zoonotic surveillance. Computational and Structural Biotechnology Journal 20, pages 5378-5392.
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Heidi L. Rehm, Angela J.H. Page, Lindsay Smith, Jeremy B. Adams, Gil Alterovitz, Lawrence J. Babb, Maxmillian P. Barkley, Michael Baudis, Michael J.S. Beauvais, Tim Beck, Jacques S. Beckmann, Sergi Beltran, David Bernick, Alexander Bernier, James K. Bonfield, Tiffany F. Boughtwood, Guillaume Bourque, Sarion R. Bowers, Anthony J. Brookes, Michael Brudno, Matthew H. Brush, David Bujold, Tony Burdett, Orion J. Buske, Moran N. Cabili, Daniel L. Cameron, Robert J. Carroll, Esmeralda Casas-Silva, Debyani Chakravarty, Bimal P. Chaudhari, Shu Hui Chen, J. Michael Cherry, Justina Chung, Melissa Cline, Hayley L. Clissold, Robert M. Cook-Deegan, Mélanie Courtot, Fiona Cunningham, Miro Cupak, Robert M. Davies, Danielle Denisko, Megan J. Doerr, Lena I. Dolman, Edward S. Dove, L. Jonathan Dursi, Stephanie O.M. Dyke, James A. Eddy, Karen Eilbeck, Kyle P. Ellrott, Susan Fairley, Khalid A. Fakhro, Helen V. Firth, Michael S. Fitzsimons, Marc Fiume, Paul Flicek, Ian M. Fore, Mallory A. Freeberg, Robert R. Freimuth, Lauren A. Fromont, Jonathan Fuerth, Clara L. Gaff, Weiniu Gan, Elena M. Ghanaim, David Glazer, Robert C. Green, Malachi Griffith, Obi L. Griffith, Robert L. Grossman, Tudor Groza, Jaime M. Guidry Auvil, Roderic Guigó, Dipayan Gupta, Melissa A. Haendel, Ada Hamosh, David P. Hansen, Reece K. Hart, Dean Mitchell Hartley, David Haussler, Rachele M. Hendricks-Sturrup, Calvin W.L. Ho, Ashley E. Hobb, Michael M. Hoffman, Oliver M. Hofmann, Petr Holub, Jacob Shujui Hsu, Jean-Pierre Hubaux, Sarah E. Hunt, Ammar Husami, Julius O. Jacobsen, Saumya S. Jamuar, Elizabeth L. Janes, Francis Jeanson, Aina Jené, Amber L. Johns, Yann Joly, Steven J.M. Jones, Alexander Kanitz, Kazuto Kato, Thomas M. Keane, Kristina Kekesi-Lafrance, Jerome Kelleher, Giselle Kerry, Seik-Soon Khor, Bartha M. Knoppers, Melissa A. Konopko, Kenjiro Kosaki, Martin Kuba, Jonathan Lawson, Rasko Leinonen, Stephanie Li, Michael F. Lin, Mikael Linden, Xianglin Liu, Isuru Udara Liyanage, Javier Lopez, Anneke M. Lucassen, Michael Lukowski, Alice L. Mann, John Marshall, Michele Mattioni, Alejandro Metke-Jimenez, Anna Middleton, Richard J. Milne, Fruzsina Molnár-Gábor, Nicola Mulder, Monica C. Munoz-Torres, Rishi Nag, Hidewaki Nakagawa, Jamal Nasir, Arcadi Navarro, Tristan H. Nelson, Ania Niewielska, Amy Nisselle, Jeffrey Niu, Tommi H. Nyrönen, Brian D. O’Connor, Sabine Oesterle, Soichi Ogishima, Vivian Ota Wang, Laura A.D. Paglione, Emilio Palumbo, Helen E. Parkinson, Anthony A. Philippakis, Angel D. Pizarro, Andreas Prlic, Jordi Rambla, Augusto Rendon, Renee A. Rider, Peter N. Robinson, Kurt W. Rodarmer, Laura Lyman Rodriguez, Alan F. Rubin, Manuel Rueda, Gregory A. Rushton, Rosalyn S. Ryan, Gary I. Saunders, Helen Schuilenburg, Torsten Schwede, Serena Scollen, Alexander Senf, Nathan C. Sheffield, Neerjah Skantharajah, Albert V. Smith, Heidi J. Sofia, Dylan Spalding, Amanda B. Spurdle, Zornitza Stark, Lincoln D. Stein, Makoto Suematsu, Patrick Tan, Jonathan A. Tedds, Alastair A. Thomson, Adrian Thorogood, Timothy L. Tickle, Katsushi Tokunaga, Juha Törnroos, David Torrents, Sean Upchurch, Alfonso Valencia, Roman Valls Guimera, Jessica Vamathevan, Susheel Varma, Danya F. Vears, Coby Viner, Craig Voisin, Alex H. Wagner, Susan E. Wallace, Brian P. Walsh, Marc S. Williams, Eva C. Winkler, Barbara J. Wold, Grant M. Wood, J. Patrick Woolley, Chisato Yamasaki, Andrew D. Yates, Christina K. Yung, Lyndon J. Zass, Ksenia Zaytseva, Junjun Zhang, Peter Goodhand, Kathryn North & Ewan Birney. (2021) GA4GH: International policies and standards for data sharing across genomic research and healthcare. Cell Genomics 1:2, pages 100029.
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Jin-Min Peng, Bin Du, Han-Yu Qin, Qian Wang & Yan Shi. (2021) Metagenomic next-generation sequencing for the diagnosis of suspected pneumonia in immunocompromised patients. Journal of Infection 82:4, pages 22-27.
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Simone Rentschler, Lars Kaiser & Hans-Peter Deigner. (2021) Emerging Options for the Diagnosis of Bacterial Infections and the Characterization of Antimicrobial Resistance. International Journal of Molecular Sciences 22:1, pages 456.
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Héloïse Rytter, Anne Jamet, Mathieu Coureuil, Alain Charbit & Elodie Ramond. (2020) Which Current and Novel Diagnostic Avenues for Bacterial Respiratory Diseases?. Frontiers in Microbiology 11.
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B. F. Walker, A. J. Armson, M. A. O’Dea, J. R. White, C. R. P. Lind & P. R. Woodland. (2020) Are viruses associated with disc herniation? A clinical case series. BMC Musculoskeletal Disorders 21:1.
Crossref
N. Van Goethem, M. J. Struelens, S. C. J. De Keersmaecker, N. H. C. Roosens, A. Robert, S. Quoilin, H. Van Oyen & B. Devleesschauwer. (2020) Perceived utility and feasibility of pathogen genomics for public health practice: a survey among public health professionals working in the field of infectious diseases, Belgium, 2019. BMC Public Health 20:1.
Crossref
John J. Weiland, Roshan Sharma Poudel, Alyssa Flobinus, David E. Cook, Gary A. Secor & Melvin D. Bolton. (2020) RNAseq Analysis of Rhizomania-Infected Sugar Beet Provides the First Genome Sequence of Beet Necrotic Yellow Vein Virus from the USA and Identifies a Novel Alphanecrovirus and Putative Satellite Viruses. Viruses 12:6, pages 626.
Crossref
Lucas G. Huggins, Anson V. Koehler, Dinh Ng-Nguyen, Stephen Wilcox, Bettina Schunack, Tawin Inpankaew & Rebecca J. Traub. (2019) Assessment of a metabarcoding approach for the characterisation of vector-borne bacteria in canines from Bangkok, Thailand. Parasites & Vectors 12:1.
Crossref
B. J. Klotoe, S. Kacimi, E. Costa-Conceicão, H. M. Gomes, R. B. Barcellos, S. Panaiotov, D. Haj Slimene, N. Sikhayeva, S. Sengstake, A. R. Schuitema, M. Akhalaia, A. Alenova, E. Zholdybayeva, P. Tarlykov, R. Anthony, G. Refrégier & C. Sola. (2019) Genomic characterization of MDR/XDR-TB in Kazakhstan by a combination of high-throughput methods predominantly shows the ongoing transmission of L2/Beijing 94–32 central Asian/Russian clusters. BMC Infectious Diseases 19:1.
Crossref
Sam El-Kamand, Alexie Papanicolaou & C. Oliver Morton. (2019) The Use of Whole Genome and Next-Generation Sequencing in the Diagnosis of Invasive Fungal Disease. Current Fungal Infection Reports 13:4, pages 284-291.
Crossref
Lucas G. Huggins, Anson V. Koehler, Dinh Ng-Nguyen, Stephen Wilcox, Bettina Schunack, Tawin Inpankaew & Rebecca J. Traub. (2019) A novel metabarcoding diagnostic tool to explore protozoan haemoparasite diversity in mammals: a proof-of-concept study using canines from the tropics. Scientific Reports 9:1.
Crossref
Kristine M. Wylie, Todd N. Wylie, Richard Buller, Brandi Herter, Maria T. Cannella & Gregory A. Storch. (2018) Detection of Viruses in Clinical Samples by Use of Metagenomic Sequencing and Targeted Sequence Capture. Journal of Clinical Microbiology 56:12.
Crossref
Caron M. Molster, Faye L. Bowman, Gemma A. Bilkey, Angela S. Cho, Belinda L. Burns, Kristen J. Nowak & Hugh J. S. Dawkins. (2018) The Evolution of Public Health Genomics: Exploring Its Past, Present, and Future. Frontiers in Public Health 6.
Crossref
Peng Li. 2018. Genotyping. Genotyping.
Arnault Tauziède-Espariat, Fabrice Chrétien, Grégory Jouvion, Homa Alde-Biassette & Paul Hofman. (2018) Pratique de la pathologie infectieuse en France en 2015. Résultats d’un questionnaire national. Annales de Pathologie 38:1, pages 55-63.
Crossref
G. Durand. (2017) The inputs of metagenomics in the diagnostic of infectious diseases. Journal des Anti-infectieux 19:3-4, pages 100-109.
Crossref
G. Jane Farrar, Matthew Carrigan, Adrian Dockery, Sophia Millington-Ward, Arpad Palfi, Naomi Chadderton, Marian Humphries, Anna Sophia Kiang, Paul F. Kenna & Pete Humphries. (2017) Toward an elucidation of the molecular genetics of inherited retinal degenerations. Human Molecular Genetics 26:R1, pages R2-R11.
Crossref
P. Parize, E. Muth, C. Richaud, M. Gratigny, B. Pilmis, A. Lamamy, J.-L. Mainardi, J. Cheval, L. de Visser, F. Jagorel, L. Ben Yahia, G. Bamba, M. Dubois, O. Join-Lambert, M. Leruez-Ville, X. Nassif, A. Lefort, F. Lanternier, F. Suarez, O. Lortholary, M. Lecuit & M. Eloit. (2017) Untargeted next-generation sequencing-based first-line diagnosis of infection in immunocompromised adults: a multicentre, blinded, prospective study. Clinical Microbiology and Infection 23:8, pages 574.e1-574.e6.
Crossref
Philippe Pérot, Marc Lecuit & Marc Eloit. (2017) Astrovirus Diagnostics. Viruses 9:1, pages 10.
Crossref
Joshua B. Gurtler, Michael P. Doyle, Jeffrey L. Kornacki, Pina M. Fratamico, Andrew G. Gehring & George C. Paoli. 2017. Foodborne Pathogens. Foodborne Pathogens 3 40 .
Matthew Carrigan, Emma Duignan, Conor P. G. Malone, Kirk Stephenson, Tahira Saad, Ciara McDermott, Andrew Green, David Keegan, Peter Humphries, Paul F. Kenna & G. Jane Farrar. (2016) Panel-Based Population Next-Generation Sequencing for Inherited Retinal Degenerations. Scientific Reports 6:1.
Crossref
Philip Burnham, Min Seong Kim, Sean Agbor-Enoh, Helen Luikart, Hannah A. Valantine, Kiran K. Khush & Iwijn De Vlaminck. (2016) Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasma. Scientific Reports 6:1.
Crossref

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