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Editorial

Lyme disease: diagnostic issues and controversies

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Lana M. Rifkin, Julie Vadboncoeur, Caroline C. Minkus, Evan N. Dunn, Ramana S. Moorthy, Nirali Bhatt, H. Nida Sen, Michael G. Taggart, Albert T. Vitale & Debra A Goldstein. (2021) The Utility of Lyme Testing in the Workup of Ocular Inflammation. Ocular Immunology and Inflammation 29:1, pages 149-153.
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Venkata Raveendra Pothineni, Mansi B Parekh, Mustafeez Mujtaba Babar, Aditya Ambati, Peter Maguire, Mohammed Inayathullah, Kwang-Min Kim, Lobat Tayebi, Hari-Hara SK Potula & Jayakumar Rajadas. (2018) In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. Drug Design, Development and Therapy 12, pages 2915-2921.
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Audun Aase, Ondrej Hajdusek, Øivind Øines, Hanne Quarsten, Peter Wilhelmsson, Tove K. Herstad, Vivian Kjelland, Radek Sima, Marie Jalovecka, Per-Eric Lindgren & Ingeborg S. Aaberge. (2016) Validate or falsify: Lessons learned from a microscopy method claimed to be useful for detecting Borrelia and Babesia organisms in human blood. Infectious Diseases 48:6, pages 411-419.
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Renata Šmit & Maarten J Postma. (2015) Lyme borreliosis: reviewing potential vaccines, clinical aspects and health economics. Expert Review of Vaccines 14:12, pages 1549-1561.
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Jianli Dong, Nahed Ismail, Eric Fitts & David H. Walker. 2024. Diagnostic Molecular Pathology. Diagnostic Molecular Pathology 175 198 .
Heather L Kopsco, Rayda K Krell, Thomas N Mather & Neeta P Connally. (2023) Identifying Trusted Sources of Lyme Disease Prevention Information Among Internet Users Connected to Academic Public Health Resources: Internet-Based Survey Study. JMIR Formative Research 7, pages e43516.
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Stacy M. Kenyon & Siaw Li Chan. (2023) A focused review on Lyme disease diagnostic testing: An update on serology algorithms, current ordering practices, and practical considerations for laboratory implementation of a new testing algorithm. Clinical Biochemistry 117, pages 4-9.
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Anne Marit Solheim, Åslaug Rudjord Lorentzen, Audun Olav Dahlberg, Heidi Øyen Flemmen, Synne Brune, Kristine Johanne Nordstrøm Forselv, Are Hugo Pripp, Margrete Halvorsen Bø, Randi Eikeland, Harald Reiso, Åse Mygland & Unn Ljøstad. (2022) Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blinded, randomised and placebo-controlled trial. Journal of Neurology, Neurosurgery & Psychiatry 93:11, pages 1222-1228.
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Giovanni Sgroi, Roberta Iatta, Piero Lovreglio, Angela Stufano, Younes Laidoudi, Jairo Alfonso Mendoza-Roldan, Marcos Antonio Bezerra-Santos, Vincenzo Veneziano, Francesco Di Gennaro, Annalisa Saracino, Maria Chironna, Claudio Bandi & Domenico Otranto. (2022) Detection of Endosymbiont Candidatus Midichloria mitochondrii and Tickborne Pathogens in Humans Exposed to Tick Bites, Italy . Emerging Infectious Diseases 28:9, pages 1824-1832.
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Venice Servellita, Jerome Bouquet, Alison Rebman, Ting Yang, Erik Samayoa, Steve Miller, Mars Stone, Marion Lanteri, Michael Busch, Patrick Tang, Muhammad Morshed, Mark J. Soloski, John Aucott & Charles Y. Chiu. (2022) A diagnostic classifier for gene expression-based identification of early Lyme disease. Communications Medicine 2:1.
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Breanna M. Scorza, Kurayi G. Mahachi, Arin D. Cox, Angela J. Toepp, Danielle Pessoa-Pereira, Phyllis Tyrrell, Jesse Buch, Jennifer A. Foltz, Dean Lee & Christine A. Petersen. (2022) Role of NK-Like CD8 + T Cells during Asymptomatic Borrelia burgdorferi Infection . Infection and Immunity 90:5.
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Ryan S. Senger, Amr Sayed Issa, Ben Agnor, Janine Talty, Alicia Hollis & John L. Robertson. (2022) Disease-Associated Multimolecular Signature in the Urine of Patients with Lyme Disease Detected Using Raman Spectroscopy and Chemometrics. Applied Spectroscopy 76:3, pages 284-299.
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. 2022. Breastfeeding. Breastfeeding e1 e151 .
Laura Cameron, Rhéa Rocque, Kailey Penner & Ian Mauro. (2021) Public perceptions of Lyme disease and climate change in southern Manitoba, Canada: making a case for strategic decoupling of climate and health messages. BMC Public Health 21:1.
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Giacomo Stroffolini, Francesco Vladimiro Segala, Tommaso Lupia, Silvia Faraoni, Luca Rossi, Laura Tomassone, Stefania Zanet, Francesco Giuseppe De Rosa, Giovanni Di Perri & Andrea Calcagno. (2021) Serology for Borrelia spp. in Northwest Italy: A Climate-Matched 10-Year Trend. Life 11:12, pages 1310.
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Philipp Breitbart, Steffen Meister, Tim Meyer & Barbara C. Gärtner. (2021) Incidence and Prevalence of Borrelia burgdorferi Antibodies in Male Professional Football Players. Clinical Journal of Sport Medicine 31:4, pages e200-e206.
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Anna T. Nesgos, Laura C. Harrington & Emily M. Mader. (2021) Experience and knowledge of Lyme disease: A scoping review of patient-provider communication. Ticks and Tick-borne Diseases 12:4, pages 101714.
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Heather L Kopsco, Roland J Duhaime & Thomas N Mather. (2021) Assessing Public Tick Identification Ability and Tick Bite Riskiness Using Passive Photograph-Based Crowdsourced Tick Surveillance. Journal of Medical Entomology 58:2, pages 837-846.
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Amy Cross, Denis Bouboulis, Craig Shimasaki & Charles Ray Jones. (2021) Case Report: PANDAS and Persistent Lyme Disease With Neuropsychiatric Symptoms: Treatment, Resolution, and Recovery. Frontiers in Psychiatry 12.
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Vasanth Jayaraman, Karthik Krishna, Yuanyuan Yang, Karenah J. Rajasekaran, Yuzheng Ou, Tianhao Wang, Kang Bei, Hari Krishnan Krishnamurthy, John J. Rajasekaran, Alex J. Rai & Daniel A. Green. (2020) An ultra-high-density protein microarray for high throughput single-tier serological detection of Lyme disease. Scientific Reports 10:1.
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A. Raffetin, A. Saunier, K. Bouiller, P. Caraux-Paz, C. Eldin, S. Gallien, R. Jouenne, A. Belkacem, J. Salomon, O. Patey, E. Talagrand-Reboul, B. Jaulhac & A. Grillon. (2020) Unconventional diagnostic tests for Lyme borreliosis: a systematic review. Clinical Microbiology and Infection 26:1, pages 51-59.
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Charles S. Pavia. 2020. Immunological Methods in Microbiology. Immunological Methods in Microbiology 41 74 .
Robert T. Schoen. (2020) Challenges in the Diagnosis and Treatment of Lyme Disease. Current Rheumatology Reports 22:1.
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Tinne Lernout, Benoît Kabamba-Mukadi, Veroniek Saegeman, Marie Tré-Hardy, Morgane de Laveleye, Tommi Asikainen, Ram Benny Dessau, Sophie Quoilin & Amber Litzroth. (2019) The value of seroprevalence data as surveillance tool for Lyme borreliosis in the general population: the experience of Belgium. BMC Public Health 19:1.
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B. Jaulhac, A. Saunier, E. Caumes, K. Bouiller, J.F. Gehanno, C. Rabaud, S. Perrot, C. Eldin, T. de Broucker, F. Roblot, J. Toubiana, F. Sellal, F. Vuillemet, C. Sordet, B. Fantin, G. Lina, C. Sobas, X. Gocko, J. Figoni, C. Chirouze, Y. Hansmann, V. Hentgen, P. Cathebras, M. Dieudonné, O. Picone, B. Bodaghi, J.P. Gangneux, B. Degeilh, H. Partouche, C. Lenormand, A. Sotto, A. Raffetin, J.J. Monsuez, C. Michel, N. Boulanger, C. Lemogne & P. Tattevin. (2019) Lyme borreliosis and other tick-borne diseases. Guidelines from the French scientific societies (II). Biological diagnosis, treatment, persistent symptoms after documented or suspected Lyme borreliosis. Médecine et Maladies Infectieuses 49:5, pages 335-346.
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Amber Carriveau, Hanna Poole & Anne Thomas. (2019) Lyme Disease. Nursing Clinics of North America 54:2, pages 261-275.
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Josiane Kirpach, Alessia Colone, Jean-Philippe Bürckert, William J. Faison, Axel R. S. X. Dubois, Regina Sinner, Anna L. Reye & Claude P. Muller. (2019) Detection of a Low Level and Heterogeneous B Cell Immune Response in Peripheral Blood of Acute Borreliosis Patients With High Throughput Sequencing. Frontiers in Immunology 10.
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Song Liu, Iris Cruz, Catherine Ramos, Paula Taleon, Ranjan Ramasamy & Jyotsna Shah. (2018) Pilot Study of Immunoblots with Recombinant Borrelia burgdorferi Antigens for Laboratory Diagnosis of Lyme Disease. Healthcare 6:3, pages 99.
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Adoracion Pegalajar-Jurado, Martin E. Schriefer, Ryan J. Welch, Marc R. Couturier, Tiffany MacKenzie, Rebecca J. Clark, Laura V. Ashton, Mark J. Delorey & Claudia R. Molins. (2018) Evaluation of Modified Two-Tiered Testing Algorithms for Lyme Disease Laboratory Diagnosis Using Well-Characterized Serum Samples. Journal of Clinical Microbiology 56:8.
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Eric Lockwood Swinebroad. (2018) Borreliosis in Sport Horse Practice. Veterinary Clinics of North America: Equine Practice 34:2, pages 313-343.
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Bent‐Are Hansen, Torgeir Finjord & Øyvind Bruserud. (2018) Autonomous dysfunction in Lyme neuroborreliosis. A case report. Clinical Case Reports 6:5, pages 901-903.
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Susan Kane Patton & Bailey Phillips. (2018) CE: Lyme Disease: Diagnosis, Treatment, and Prevention. AJN, American Journal of Nursing 118:4, pages 38-45.
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T.J. Divers, R.B. Gardner, J.E. Madigan, S.G. Witonsky, J.J. Bertone, E.L. Swinebroad, S.E. Schutzer & A.L. Johnson. (2018) Borrelia burgdorferi Infection and Lyme Disease in North American Horses: A Consensus Statement . Journal of Veterinary Internal Medicine 32:2, pages 617-632.
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Fredrikke Christie Knudtzen, Nanna Skaarup Andersen, Thøger Gorm Jensen & Sigurdur Skarphédinsson. (2017) Characteristics and Clinical Outcome of Lyme Neuroborreliosis in a High Endemic Area, 1995–2014: A Retrospective Cohort Study in Denmark. Clinical Infectious Diseases 65:9, pages 1489-1495.
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Jaan Peter Naktin. (2017) “Late You Come: Legislation on Lyme Treatment in an Era of Conflicting Guidelines”. Open Forum Infectious Diseases 4:4.
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N. Yiannakoulias, R. Tooby & S.L. Sturrock. (2017) Celebrity over science? An analysis of Lyme disease video content on YouTube. Social Science & Medicine 191, pages 57-60.
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Eugene D. Shapiro, Phillip J. Baker & Gary P. Wormser. (2017) False and Misleading Information About Lyme Disease. The American Journal of Medicine 130:7, pages 771-772.
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Venkata Raveendra Pothineni, Dhananjay Wagh, Mustafeez Mujtaba Babar, Mohammed Inayathullah, R Edward Watts, Kwang-Min Kim, Mansi B Parekh, Abhijit Achyut Gurjarpadhye, David Solow-Cordero, Lobat Tayebi & Jayakumar Rajadas. (2016) Screening of NCI-DTP library to identify new drug candidates for Borrelia burgdorferi. The Journal of Antibiotics 70:3, pages 308-312.
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J. Dong, N. Ismail & D.H. Walker. 2017. Diagnostic Molecular Pathology. Diagnostic Molecular Pathology 179 200 .
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Claudia R. Molins, Mark J. Delorey, Christopher Sexton & Martin E. Schriefer. (2016) Lyme Borreliosis Serology: Performance of Several Commonly Used Laboratory Diagnostic Tests and a Large Resource Panel of Well-Characterized Patient Samples. Journal of Clinical Microbiology 54:11, pages 2726-2734.
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Serena Bonin. (2016) Diagnostic Tools for Borrelia Assessment in Humans. The Open Dermatology Journal 10:1, pages 62-69.
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Xenia Naj & Stefan Linder. 2017. The Actin Cytoskeleton and Bacterial Infection. The Actin Cytoskeleton and Bacterial Infection 133 154 .
Uwe Koedel, Volker Fingerle & Hans-Walter Pfister. (2015) Lyme neuroborreliosis—epidemiology, diagnosis and management. Nature Reviews Neurology 11:8, pages 446-456.
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