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Review

Neuroprotection in Parkinson’s disease: love story or mission impossible?

Pages 403-416 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Shadab Md, Shadabul Haque, Jasjeet Kaur Sahni, Sanjula Baboota & Javed Ali. (2011) New non-oral drug delivery systems for Parkinson's disease treatment. Expert Opinion on Drug Delivery 8:3, pages 359-374.
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Michael J Aminoff. (2003) Neuroprotective treatment for Parkinson’s disease. Expert Review of Neurotherapeutics 3:6, pages 797-804.
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Articles from other publishers (18)

N. Poovaiah, Z. Davoudi, H. Peng, B. Schlichtmann, S. Mallapragada, B. Narasimhan & Q. Wang. (2018) Treatment of neurodegenerative disorders through the blood–brain barrier using nanocarriers. Nanoscale 10:36, pages 16962-16983.
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Kai Liu, Huamin Xu, Hengwei Xiang, Peng Sun & Junxia Xie. (2015) Protective effects of Ndfip1 on MPP+-induced apoptosis in MES23.5 cells and its underlying mechanisms. Experimental Neurology 273, pages 215-224.
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ZeGang Ma, Yu Zhou & JunXia Xie. (2012) Nifedipine Prevents Iron Accumulation and Reverses Iron-Overload-Induced Dopamine Neuron Degeneration in the Substantia Nigra of Rats. Neurotoxicity Research 22:4, pages 274-279.
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Rong Wang, Zegang Ma, Jun Wang & Junxia Xie. (2011) L-Type Cav1.2 Calcium Channel is Involved in 6-Hydroxydopamine-Induced Neurotoxicity in Rats. Neurotoxicity Research 21:3, pages 266-270.
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Kai Zhang, ZeGang Ma, Jun Wang, AnMu Xie & JunXia Xie. (2011) Myricetin attenuated MPP+-induced cytotoxicity by anti-oxidation and inhibition of MKK4 and JNK activation in MES23.5 cells. Neuropharmacology 61:1-2, pages 329-335.
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Jun Wang, Hua-Min Xu, Hai-Dong Yang, Xi-Xun Du, Hong Jiang & Jun-Xia Xie. (2009) Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins. Neurochemistry International 54:1, pages 43-48.
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G. Linazasoro. (2008) Potential applications of nanotechnologies to Parkinson's disease therapy. Parkinsonism & Related Disorders 14:5, pages 383-392.
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Yael Avramovich-Tirosh, Tamar Amit, Orit Bar-Am, Hailin Zheng, Mati Fridkin & Moussa B. H. Youdim. (2007) Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator?monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease. Journal of Neurochemistry 100:2, pages 490-502.
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Justyna Ostrowska, Wojciech Łuczaj, Agnieszka Augustyniak & Elżbieta Skrzydlewska. 2007. Oxidative Stress and Neurodegenerative Disorders. Oxidative Stress and Neurodegenerative Disorders 581 605 .
Silvia Mandel, Tamar Amit, Lydia Reznichenko, Orly Weinreb & Moussa B. H. Youdim. (2006) Green tea catechins as brain‐permeable, natural iron chelators‐antioxidants for the treatment of neurodegenerative disorders. Molecular Nutrition & Food Research 50:2, pages 229-234.
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S. Mandel, O. Weinreb, L. Reznichenko, L. Kalfon & T. Amit. 2006. Oxidative Stress and Neuroprotection. Oxidative Stress and Neuroprotection 249 257 .
Silvia Mandel, Tamar Amit, Moussa Youdim & Orly Weinreb. 2005. Molecular Interventions in Lifestyle-Related Diseases. Molecular Interventions in Lifestyle-Related Diseases 155 174 .
Silvia A. Mandel, Yael Avramovich-Tirosh, Lydia Reznichenko, Hailin Zheng, Orly Weinreb, Tamar Amit & Moussa B.H. Youdim. (2005) Multifunctional Activities of Green Tea Catechins in Neuroprotection. Neurosignals 14:1-2, pages 46-60.
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Orly Weinreb, Silvia Mandel, Tamar Amit & Moussa B.H. Youdim. (2004) Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases. The Journal of Nutritional Biochemistry 15:9, pages 506-516.
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Silvia Mandel & Moussa B.H Youdim. (2004) Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases. Free Radical Biology and Medicine 37:3, pages 304-317.
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Silvia Mandel, Orly Weinreb, Tamar Amit & Moussa B. H. Youdim. (2004) Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases. Journal of Neurochemistry 88:6, pages 1555-1569.
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Silvia Mandel, Orly Weinreb & Moussa B.H Youdim. (2003) Using cDNA microarray to assess Parkinson's disease models and the effects of neuroprotective drugs. Trends in Pharmacological Sciences 24:4, pages 184-191.
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Silvia Mandel, Edna Gr??nblatt, Peter Riederer, Manfred Gerlach, Yona Levites & Moussa B H Youdim. (2003) Neuroprotective Strategies in Parkinson???s Disease. CNS Drugs 17:10, pages 729-762.
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