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The safety and tolerability of intranasal midazolam in epilepsy

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James W Wheless. (2021) A critical evaluation of midazolam nasal spray for the treatment of patients with seizure clusters. Expert Review of Neurotherapeutics 21:11, pages 1195-1205.
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Alberto Verrotti, Maddalena Milioni & Gaetano Zaccara. (2015) Safety and efficacy of diazepam autoinjector for the management of epilepsy. Expert Review of Neurotherapeutics 15:2, pages 127-133.
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Articles from other publishers (20)

Muhammad Usman Khan, Xinyu Cai, Zhiwei Shen, Taye Mekonnen, Agisilaos Kourmatzis, Shaokoon Cheng & Hanieh Gholizadeh. (2023) Challenges in the Development and Application of Organ-on-Chips for Intranasal Drug Delivery Studies. Pharmaceutics 15:5, pages 1557.
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Li Du, Lin Chen, Fangfang Liu, Wenya Wang & Hongyun Huang. 2023. Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors. Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors 255 297 .
Vivek P. Chavda, Gargi Jogi, Nirav Shah, Mansi N. Athalye, Nirav Bamaniya, Lalitkumar K Vora & Ana Cláudia Paiva-Santos. (2022) Advanced particulate carrier-mediated technologies for nasal drug delivery. Journal of Drug Delivery Science and Technology 74, pages 103569.
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Hui Wang, Jie Huang, Shuang Yang, Xing-fei Zhang, Xiaoyan Yang, Chang Cui, Chan Zou, Li-e Li, Min Zhang, Miao-fu Mao, Xiang Zhou, Kai-ming Duan, Sai-ying Wang & Guo-ping Yang. (2022) Bioavailability and Safety of a New Highly Concentrated Midazolam Nasal Spray Compared to Buccal and Intravenous Midazolam Treatment in Chinese Healthy Volunteers. Neurology and Therapy 11:2, pages 621-632.
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Fa-Zhi Su, Chen-Xi Bai, Yumeng Luo, Wen-Sen Zhang, Na Cui, Yang-Yang Wang, Yan-Ping Sun, Wen-Bo Zhu, Ming-Yang Zhao, Bing-You Yang, Hai-Xue Kuang & Qiu-Hong Wang. (2022) Cattle Bile Arisaema Aqueous Extracts Protect Against Febrile Seizures in Rats Through Regulating Neurotransmitters and Suppressing Neuroinflammation. Frontiers in Pharmacology 13.
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Lea-Adriana Keller, Olivia Merkel & Andreas Popp. (2021) Intranasal drug delivery: opportunities and toxicologic challenges during drug development. Drug Delivery and Translational Research 12:4, pages 735-757.
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David M. Taylor, Thomas R. E. Barnes & Allan H. Young. 2021. The Maudsley Prescribing Guidelines in Psychiatry. The Maudsley Prescribing Guidelines in Psychiatry 305 450 .
M. René Bouw, Steve S. Chung, Barry Gidal, Aliceson King, Jerry Tomasovic, James W. Wheless & Peter J. Van Ess. (2021) Clinical pharmacokinetic and pharmacodynamic profile of midazolam nasal spray. Epilepsy Research 171, pages 106567.
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I. M. Ivanov, A. S. Nikiforov, M. A. Yudin, A. M. Sventitskaya & V. S. Pavlova. (2020) Prospects for the development of inhalation drugs for the provision of pre-hospital assistance to affected by hazardous chemical substances. Bulletin of the Russian Military Medical Academy 22:3, pages 176-181.
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Yangshun Tang, Bo Feng, Yi Wang, Huiyong Sun, Yi You, Jie Yu, Bin Chen, Cenglin Xu, Yeping Ruan, Sunliang Cui, Gang Hu, Tingjun Hou & Zhong Chen. (2020) Structure‐based discovery of CZL80, a caspase‐1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. British Journal of Pharmacology 177:15, pages 3519-3534.
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Raoul Sutter & Peter W. Kaplan. (2020) Transnasal Revolution? The Promise of Midazolam Spray to Prevent Seizure Clusters. CNS Drugs 34:5, pages 555-557.
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Anemone von Blomberg, Lara Kay, Susanne Knake, Sven Fuest, Johann Philipp Zöllner, Philipp S. Reif, Eva Herrmann, Ümniye Balaban, Susanne Schubert-Bast, Felix Rosenow & Adam Strzelczyk. (2020) Efficacy, Tolerability, and Safety of Concentrated Intranasal Midazolam Spray as Emergency Medication in Epilepsy Patients During Video-EEG Monitoring. CNS Drugs 34:5, pages 545-553.
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Samuel J. PernaJames M. RhinewaltErin R. Currie. (2018) Seizing the Opportunity: Exploring Barriers to Use of Transmucosal Midazolam in Hospice Patients. Journal of Palliative Medicine 21:5, pages 674-677.
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James J. Riviello. 2018. Status Epilepticus. Status Epilepticus 333 352 .
Eytan Shtull-Leber, Robert Silbergleit & William J. Meurer. (2017) Pre-hospital midazolam for benzodiazepine-treated seizures before and after the Rapid Anticonvulsant Medication Prior to Arrival Trial: A national observational cohort study. PLOS ONE 12:3, pages e0173539.
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Marco Mula. (2016) New Non-Intravenous Routes for Benzodiazepines in Epilepsy: A Clinician Perspective. CNS Drugs 31:1, pages 11-17.
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Lara Kay, Philipp S. Reif, Marcus Belke, Sebastian Bauer, Detlef Fründ, Susanne Knake, Felix Rosenow & Adam Strzelczyk. (2015) Intranasal midazolam during presurgical epilepsy monitoring is well tolerated, delays seizure recurrence, and protects from generalized tonic-clonic seizures. Epilepsia 56:9, pages 1408-1414.
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Francesco Brigo, Raffaele Nardone, Frediano Tezzon & Eugen Trinka. (2015) A Common Reference-Based Indirect Comparison Meta-Analysis of Buccal versus Intranasal Midazolam for Early Status Epilepticus. CNS Drugs 29:9, pages 741-757.
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