Advanced search
Publication Cover
Expert Review of Neurotherapeutics Volume 14, 2014 - Issue 9
Submit an article Journal homepage
821
Views
52
CrossRef citations to date
0
Altmetric
Reviews

Lithium for bipolar disorder: a review of the recent literature

Genevieve CurranDivision of Mood and Anxiety Disorders, Centre for Addiction and Mental Health, Bell Gateway Building, 100 Stokes St, Toronto, ON M6J 1H4, Canada
&
Arun RavindranDepartment of Psychiatry, University of Toronto,CanadaCorrespondence[email protected]
Pages 1079-1098 | Published online: 18 Aug 2014

Citations (52)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Jeremy Mills. (2022) Lithium: The Oldest-Known Metal in the Universe Can Prevent Suicide, and Nurses Should Be Using It More. Issues in Mental Health Nursing 43:2, pages 193-197.
Read now
Alfredo Carlo Altamura, Marta Serati & Massimiliano Buoli. (2015) Is duration of illness really influencing outcome in major psychoses?. Nordic Journal of Psychiatry 69:6, pages 1685-1699.
Read now

Articles from other publishers (50)

Ahmad H Almadani, Fay H AlBuqami & Mohammed A Aljaffer. (2023) Challenges in the Clinical Diagnosis of Lithium Toxicity: A Case Report. Cureus.
Crossref
Annemiek DolsHarmehr SekhonSoham RejFederica KlausKatie BodensteinMartha Sajatovic. (2023) Bipolar Disorder Among Older Adults: Newer Evidence to Guide Clinical Practice. FOCUS 21:4, pages 370-379.
Crossref
Samreen Shafiq, Paul Everett Ronksley, Tayler Dawn Scory, Meghan Jessica Elliott, Andrew Gabriel McKay Bulloch & Scott Burton Patten. (2023) Ten-Year Trends in Lithium Prescribing in Alberta, Canada. The Canadian Journal of Psychiatry, pages 070674372311769.
Crossref
Giphy Susan Varghese, Karthikkeyan Rajachandran & Indhupriyadharshini Murugesan. (2023) Insights into Chronic Lithium Toxicity - A Case Report. Current Drug Safety 18:1, pages 112-115.
Crossref
Siavash Fazel Darbandi, Andrew D. Nelson, Emily Ling-lin Pai, Kevin J. Bender & John L. R. Rubenstein. (2022) LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants. Journal of Neurodevelopmental Disorders 14:1.
Crossref
Taise Possamai-Della, Gustavo C. Dal-Pont, Wilson R. Resende, Jorge M. Aguiar-Geraldo, Jefté Peper-Nascimento, João Quevedo & Samira S. Valvassori. (2022) Imipramine Can Be Effective on Depressive-Like Behaviors, but Not on Neurotrophic Factor Levels in an Animal Model for Bipolar Disorder Induced by Ouabain. Molecular Neurobiology 59:12, pages 7170-7181.
Crossref
Gohar Parsadanyan & Armen Nersesyan. (2022) Are lithium and its salts genotoxic? Re: Hadrup et al. Pulmonary toxicity, genotoxicity, and carcinogenicity evaluation of molybdenum, lithium, and tungsten: A review. Toxicology 467 (2022) 153098. Toxicology 479, pages 153298.
Crossref
Arihant Singh, Tanishq Kumar, Vivek R Velagala, Swedaj Thakre & Abhishek Joshi. (2022) The Actions of Lithium on Glaucoma and Other Senile Neurodegenerative Diseases Through GSK-3 Inhibition: A Narrative Review. Cureus.
Crossref
Hanna Jaaro-Peled, Sunil Kumar, Dalton Hughes, Akiko Sumitomo, Sun-Hong Kim, Sandra Zoubovsky, Yuki Hirota-Tsuyada, Diana Zala, Julie Bruyere, Brittany M. Katz, Beverly Huang, Rafael FloresIIIIII, Soumya Narayan, Zhipeng Hou, Aris N. Economides, Takatoshi Hikida, William C. Wetsel, Karl Deisseroth, Susumu Mori, Nicholas J. Brandon, Motomasa Tanaka, Koko Ishizuka, Miles D. Houslay, Frédéric Saudou, Kafui Dzirasa, Akira Sawa & Toshifumi Tomoda. (2022) Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit. Molecular Psychiatry 27:3, pages 1805-1815.
Crossref
Enrique L. M. Ochoa. (2021) Lithium as a Neuroprotective Agent for Bipolar Disorder: An Overview. Cellular and Molecular Neurobiology 42:1, pages 85-97.
Crossref
Johanna Seifert, Stefan Bleich & Roland Seifert. 2022. Arzneiverordnungs-Report 2022. Arzneiverordnungs-Report 2022 451 495 .
Yung-Shih Lee, Chien-Wei Feng, Mei-Yu Peng, Te-Fu Chan & Yu-Chieh Chen. (2021) Neuroprotective Effects of Estradiol plus Lithium Chloride via Anti-Apoptosis and Neurogenesis Pathway in In Vitro and In Vivo Parkinson’s Disease Models. Parkinson's Disease 2021, pages 1-15.
Crossref
Çağdaş Hünkar YELOĞLU, Çiçek HOCAOĞLU & Bülent BAHÇECİ. (2021) Bipolar Bozukluk Tanısı ile İzlenen Hastalarda İşlevsellik ve Kişilik Özelliklerinin Koruyucu Tedavi Üzerine Olan Etkisinin İncelenmesiEffect of personality traits on functioning and long-term treatment in patients with bipolar disorder. Genel Tıp Dergisi 31:3, pages 189-195.
Crossref
William H. Schlesinger, Emily M. Klein, Zhen Wang & Avner Vengosh. (2021) Global Biogeochemical Cycle of Lithium. Global Biogeochemical Cycles 35:8.
Crossref
Kamal Shokeen, Ariktha Srivathsan & Sachin Kumar. (2021) Lithium chloride functions as Newcastle disease virus-induced ER-stress modulator and confers anti-viral effect. Virus Research 292, pages 198223.
Crossref
Marco Pinna, Mirko Manchia, Caterina Visioli & Leonardo Tondo. (2020) Clinical response and metabolic effects of lithium in 323 mood disorder patients. Journal of Affective Disorders 270, pages 9-14.
Crossref
Emanuela Stampone, Debora Bencivenga, Clementina Barone, Arianna Aulitto, Federica Verace, Fulvio Della Ragione & Adriana Borriello. (2020) High Dosage Lithium Treatment Induces DNA Damage and p57Kip2 Decrease. International Journal of Molecular Sciences 21:3, pages 1169.
Crossref
VIRGINIA FERNANDES, MAYCE AL-SUKHNI, ANDREA LAWSON & GREGORY CHANDLER. (2020) Lithium Prescribing and Therapeutic Drug Monitoring in Bipolar Disorder: A Survey of Current Practices and Perspectives. Journal of Psychiatric Practice 26:5, pages 360-366.
Crossref
Nobue Kitanaka, Frank Scott Hall, George Richard Uhl & Junichi Kitanaka. (2019) Lithium Pharmacology and a Potential Role of Lithium on Methamphetamine Abuse and Dependence. Current Drug Research Reviews 11:2, pages 85-91.
Crossref
Gustavo C. Dal-Pont, Marco T.S. Jório, Wilson R. Resende, Fernanda F. Gava, Jorge M. Aguiar-Geraldo, Taise Possamai-Della, Jefté Peper-Nascimento, João Quevedo & Samira S. Valvassori. (2019) Effects of lithium and valproate on behavioral parameters and neurotrophic factor levels in an animal model of mania induced by paradoxical sleep deprivation. Journal of Psychiatric Research 119, pages 76-83.
Crossref
Jared Ng, Manne Sjöstrand & Nir Eyal. (2019) Adding Lithium to Drinking Water for Suicide Prevention—The Ethics. Public Health Ethics 12:3, pages 274-286.
Crossref
Muhamad N.A. Kamarudin & Ishwar Parhar. (2019) Emerging therapeutic potential of anti-psychotic drugs in the management of human glioma: A comprehensive review. Oncotarget 10:39, pages 3952-3977.
Crossref
David Holland, Christopher J. Duff, Sanam Farman, Anthony A. Fryer, Alison Yung, Susan Bailey & Adrian H. Heald. (2019) More frequent lithium testing in UK Primary Care associates with a lower hospital admission rate for bipolar disorder—What this can tell us about GP practice engagement with this group . International Journal of Clinical Practice 73:4, pages e13277.
Crossref
M. A. Corrigan, T. M. Ferradaes, M. Riffault & D. A. Hoey. (2018) Ciliotherapy Treatments to Enhance Biochemically- and Biophysically-Induced Mesenchymal Stem Cell Osteogenesis: A Comparison Study. Cellular and Molecular Bioengineering 12:1, pages 53-67.
Crossref
Jason Boswell, Holly Lowe, Katherine Adorati, Sidhartha D. Ray & Connie Rust. 2019. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions 27 31 .
Hazan TOMAR BOZKURT, Vefa Erbasan, Ümran Eğilmez, Barış Şen, Memduha Aydın & Kürşat Altınbaş. (2018) Lityuma Tedavi Yanıtının Klinik, Biyolojik ve Genetik YordayıcılarıClinical, Biological and Genetic Predictors of Lithium Treatment Response. Psikiyatride Güncel Yaklaşımlar 10:4, pages 405-426.
Crossref
Wael Mahmoud Aboulthana & Noha El-Sayed Ibrahim. (2018) A renoprotective role of chitosan against lithium-induced renal toxicity in rats. Bulletin of the National Research Centre 42:1.
Crossref
Ana González-Pinto, Purificación López-Peña, Cristina Bermúdez-Ampudia, Eduard Vieta & Mónica Martinez-Cengotitabengoa. (2018) Can lithium salts prevent depressive episodes in the real world?. European Neuropsychopharmacology 28:12, pages 1351-1359.
Crossref
B. D. Kelly. (2017) Are we finally making progress with suicide and self-harm? An overview of the history, epidemiology and evidence for prevention. Irish Journal of Psychological Medicine 35:2, pages 95-101.
Crossref
Hong-jie Li, Dong-sheng Gao, Yong-tao Li, Yong-sheng Wang, Hong-ying Liu & Jun Zhao. (2018) Antiviral effect of lithium chloride on porcine epidemic diarrhea virus in vitro. Research in Veterinary Science 118, pages 288-294.
Crossref
Mikael Tiger, Katarina Varnäs, Yoshiro Okubo & Johan Lundberg. (2018) The 5-HT1B receptor - a potential target for antidepressant treatment. Psychopharmacology 235:5, pages 1317-1334.
Crossref
Eunsoo Won & Yong-Ku Kim. (2017) An Oldie but Goodie: Lithium in the Treatment of Bipolar Disorder through Neuroprotective and Neurotrophic Mechanisms. International Journal of Molecular Sciences 18:12, pages 2679.
Crossref
Julia C. Golden, John W. Goethe & Stephen B. Woolley. (2017) Complex psychotropic polypharmacy in bipolar disorder across varying mood polarities: A prospective cohort study of 2712 inpatients. Journal of Affective Disorders 221, pages 6-10.
Crossref
Ефим (Efim) Авраамович (Avraamovich) Краснов (Krasnov)Елена (Elena) Евгеньевна (Evgen'evna) Савельева (Savelyeva)Надежда (Nadezhda) Кирилловна (Kirillovna) Рыжакова (Ryzhakova)Ярослав (Yaroslav) Евгеньевич (Evgen'evich) Решетов (Reshetov)Альбина (Al'bina) Равильевна (Ravil'evna) Гатауллина (Gataullina). (2017) THE STUDY OF THE DOMINANT GROUPS OF BIOLOGICALLY ACTIVE SUBSTANCES AND BIOELEMENTS IN SOME PLANTS OF THE FAMILY ROSACEAE. chemistry of plant raw material:4, pages 145-151.
Crossref
Sa'ed H. Zyoud, W. Stephen Waring, Waleed M. Sweileh & Samah W. Al-Jabi. (2017) Global Research Trends in Lithium Toxicity from 1913 to 2015: A Bibliometric Analysis. Basic & Clinical Pharmacology & Toxicology 121:1, pages 67-73.
Crossref
Sabine B. Schleicher, Julian J. Zaborski, Rosa Riester, Natascha Zenkner, Rupert Handgretinger, Torsten Kluba, Frank Traub & Karen A. Boehme. (2017) Combined application of arsenic trioxide and lithium chloride augments viability reduction and apoptosis induction in human rhabdomyosarcoma cell lines. PLOS ONE 12:6, pages e0178857.
Crossref
Ali Mezni, Abdelhafidh Khazri, Olfa Khazri, Ferid Limam, Pascal Cosette & Ezzeddine Aouani. (2016) Neuroprotective Activity of Grape Seed and Skin Extract Against Lithium Exposure Using Proteomic Research. Molecular Neurobiology 54:4, pages 2720-2730.
Crossref
Takuya Furuta, Hemragul Sabit, Yu Dong, Katsuyoshi Miyashita, Masashi Kinoshita, Naoyuki Uchiyama, Yasuhiko Hayashi, Yutaka Hayashi, Toshinari Minamoto & Mitsutoshi Nakada. (2017) Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma. Oncotarget 8:14, pages 22811-22824.
Crossref
Susana Alberich, Mónica Martínez-Cengotitabengoa, Purificación López, Iñaki Zorrilla, Nuria Núñez, Eduard Vieta & Ana González-Pinto. (2017) Efficacy and safety of ketamine in bipolar depression: A systematic review. Revista de Psiquiatría y Salud Mental (English Edition) 10:2, pages 104-112.
Crossref
Susana Alberich, Mónica Martínez-Cengotitabengoa, Purificación López, Iñaki Zorrilla, Nuria Núñez, Eduard Vieta & Ana González-Pinto. (2017) Eficacia y seguridad de la ketamina en depresión bipolar: una revisión sistemática. Revista de Psiquiatría y Salud Mental 10:2, pages 104-112.
Crossref
Isabel Pérez-Castelló, Víctor Mangas-Sanjuan, Ignacio González-García, Isabel Gonzalez-Alvarez, Marival Bermejo, Jose Luis Marco-Garbayo & Iñaki F. Trocóniz. (2016) Population pharmacokinetic model of lithium and drug compliance assessment. European Neuropsychopharmacology 26:12, pages 1868-1876.
Crossref
E.I. Solntseva, J.V. Bukanova, R.V. Kondratenko & V.G. Skrebitsky. (2016) Lithium ions in nanomolar concentration modulate glycine-activated chloride current in rat hippocampal neurons. Neurochemistry International 94, pages 67-73.
Crossref
Zhiwen Zeng, Haitao Wang, Fu Shang, Lihua Zhou, Peter J. Little, Remi Quirion & Wenhua Zheng. (2015) Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways. Psychopharmacology 233:5, pages 785-794.
Crossref
Terence A. Ketter, Shefali Miller, Bernardo Dell’Osso & Po W. Wang. (2016) Treatment of bipolar disorder: Review of evidence regarding quetiapine and lithium. Journal of Affective Disorders 191, pages 256-273.
Crossref
Alencar Kolinski Machado, Ana Cristina Andreazza, Tatiane Morgana da Silva, Aline Augusti Boligon, Vanusa do Nascimento, Gustavo Scola, Angela Duong, Francine Carla Cadoná, Euler Esteves Ribeiro & Ivana Beatrice Mânica da Cruz. (2016) Neuroprotective Effects of Açaí ( Euterpe oleracea Mart.) against Rotenone In Vitro Exposure . Oxidative Medicine and Cellular Longevity 2016, pages 1-14.
Crossref
Philip G. Janicak & Bradley R. Cutler. 2011. Encyclopedia of Inorganic and Bioinorganic Chemistry. Encyclopedia of Inorganic and Bioinorganic Chemistry 1 9 .
John W. Scott, Elizabeth Park, Ramona M. Rodriguiz, Jonathan S. Oakhill, Samah M. A. Issa, Matthew T. O’Brien, Toby A. Dite, Christopher G. Langendorf, William C. Wetsel, Anthony R. Means & Bruce E. Kemp. (2015) Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder. Scientific Reports 5:1.
Crossref
Zhu Zhou, Ying Wang, Hua Tan, Veni Bharti, Yi Che & Jun-Feng Wang. (2015) Chronic treatment with mood stabilizer lithium inhibits amphetamine-induced risk-taking manic-like behaviors. Neuroscience Letters 603, pages 84-88.
Crossref
Camila O. Arent, Samira S. Valvassori, Amanda V. Steckert, Wilson R. Resende, Gustavo C. Dal-Pont, Jéssica Lopes-Borges, Rafaela T. Amboni, Guilherme Bianchini & João Quevedo. (2015) The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania. Journal of Psychiatric Research 65, pages 71-79.
Crossref
Kostas N. FountoulakisKostas N. Fountoulakis. 2015. Bipolar Disorder. Bipolar Disorder 659 684 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.