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Targeting astrocytes in major depression

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Liang Peng, Dan Song, Baoman Li & Alexei Verkhratsky. (2018) Astroglial 5-HT2B receptor in mood disorders. Expert Review of Neurotherapeutics 18:5, pages 435-442.
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Lan Lei, Ya-Ting Wang, Die Hu, Cong Gai & Yi Zhang. (2023) Astroglial Connexin 43-Mediated Gap Junctions and Hemichannels: Potential Antidepressant Mechanisms and the Link to Neuroinflammation. Cellular and Molecular Neurobiology 43:8, pages 4023-4040.
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Alexei Verkhratsky, Arthur Butt, Baoman Li, Peter Illes, Robert Zorec, Alexey Semyanov, Yong Tang & Michael V. Sofroniew. (2023) Astrocytes in human central nervous system diseases: a frontier for new therapies. Signal Transduction and Targeted Therapy 8:1.
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Ana Carolina P. Campos, Rosana L. Pagano, Nir Lipsman & Clement Hamani. (2023) What do we know about astrocytes and the antidepressant effects of DBS?. Experimental Neurology 368, pages 114501.
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Dongqing Jing, Xiaoli Hou, Xiao Guo, Xin Zhao, Kexin Zhang, Jingwen Zhang, Chengxia Kan, Fang Han, Junling Liu & Xiaodong Sun. (2023) Astrocytes in Post-Stroke Depression: Roles in Inflammation, Neurotransmission, and Neurotrophin Signaling. Cellular and Molecular Neurobiology.
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Xinxin Yu, Shihao Wang, Wenzheng Wu, Hongyuan Chang, Pufan Shan, Lin Yang, Wenjie Zhang & Xiaoyu Wang. (2023) Exploring New Mechanism of Depression from the Effects of Virus on Nerve Cells. Cells 12:13, pages 1767.
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Yu-Bing Wang, Ning-Ning Song, Yu-Qiang Ding & Lei Zhang. (2023) Neural plasticity and depression treatment. IBRO Neuroscience Reports 14, pages 160-184.
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Si-Si Lin, Bin Zhou, Bin-Jie Chen, Ruo-Tian Jiang, Baoman Li, Peter Illes, Alexey Semyanov, Yong Tang & Alexei Verkhratsky. (2023) Electroacupuncture prevents astrocyte atrophy to alleviate depression. Cell Death & Disease 14:5.
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Agneta Nordberg, Alexey Semyanov, Vladimir Parpura & Robert Zorec. (2023) Alexei Verkhratsky, the Philosopher of Neuroglia. Preface for the Honorary Issue of Neurochemical Research. Neurochemical Research 48:4, pages 1009-1014.
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Hailun Jiang, Shizhe Deng, Jieying Zhang, Junjie Chen, Boxuan Li, Weiming Zhu, Menglong Zhang, Chao Zhang & Zhihong Meng. (2023) Acupuncture treatment for post-stroke depression: Intestinal microbiota and its role. Frontiers in Neuroscience 17.
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Xin-hui Xie, Wen-tao Lai, Shu-xian Xu, Marta Di Forti, Jing-ya Zhang, Mian-mian Chen, Li-hua Yao, Peilin Wang, Ke-ke Hao & Han Rong. (2023) Hyper-inflammation of astrocytes in patients of major depressive disorder: Evidence from serum astrocyte-derived extracellular vesicles. Brain, Behavior, and Immunity 109, pages 51-62.
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Y.F. Zhao, A. Verkhratsky, Y. Tang & P. Illes. (2022) Astrocytes and major depression: The purinergic avenue. Neuropharmacology 220, pages 109252.
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Dujuan Huang, Qian Xiao, Jing Tang, Xin Liang, Jin Wang, Menglan Hu, Yanhong Jiang, Li Liu, Lu Qin, Mei Zhou, Yue Li, Peilin Zhu, Yuhui Deng, Jing Li, Chunni Zhou, Yanmin Luo & Yong Tang. (2022) Positive effects of running exercise on astrocytes in the medial prefrontal cortex in an animal model of depression. Journal of Comparative Neurology 530:17, pages 3056-3071.
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Shusheng Wu, Yuye Yin & Longfei Du. (2021) Blood–Brain Barrier Dysfunction in the Pathogenesis of Major Depressive Disorder. Cellular and Molecular Neurobiology 42:8, pages 2571-2591.
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Ronald Kim, Anze Testen, Eden V. Harder, Natalie E. Brown, Emily A. Witt, Tania J. Bellinger, Janay P. Franklin & Kathryn J. Reissner. (2022) Abstinence-Dependent Effects of Long-Access Cocaine Self-Administration on Nucleus Accumbens Astrocytes Are Observed in Male, But Not Female, Rats. eneuro 9:5, pages ENEURO.0310-22.2022.
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Shu‐Man Pan, Ying Pan, Ya‐Li Tang, Na Zuo, Yan‐Xiu Zhang, Ke‐Ke Jia & Ling‐Dong Kong. (2021) Thioredoxin interacting protein drives astrocytic glucose hypometabolism in corticosterone‐induced depressive state. Journal of Neurochemistry 161:1, pages 84-100.
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Ya-Fei Zhao, Wen-Jing Ren, Ying Zhang, Jin-Rong He, Hai-Yan Yin, Yang Liao, Patrizia Rubini, Jan M. Deussing, Alexei Verkhratsky, Zeng-Qiang Yuan, Peter Illes & Yong Tang. (2022) High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus. International Journal of Molecular Sciences 23:3, pages 1904.
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Beina Chen, Manman Zhang, Ming Ji, Wenliang Gong, Binjie Chen, Robert Zorec, Matjaž Stenovec, Alexei Verkhratsky & Baoman Li. (2021) The Association Between Antidepressant Effect of SSRIs and Astrocytes: Conceptual Overview and Meta‐analysis of the Literature. Neurochemical Research 46:10, pages 2731-2745.
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Franziska E. Müller, Sophie K. Schade, Volodymyr Cherkas, Laura Stopper, Björn Breithausen, Daniel Minge, Hristo Varbanov, Christian Wahl‐Schott, Svitlana Antoniuk, Catia Domingos, Valérie Compan, Frank Kirchhoff, Christian Henneberger, Evgeni Ponimaskin & Andre Zeug. (2020) Serotonin receptor 4 regulates hippocampal astrocyte morphology and function. Glia 69:4, pages 872-889.
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Konstantin A. Demin, Dmitry A. Smagin, Irina L. Kovalenko, Tatyana Strekalova, David S. Galstyan, Tatyana O. Kolesnikova, Murilo S. De Abreu, Anna G. Galyamina, Alim Bashirzade & Allan V. Kalueff. (2021) CNS genomic profiling in the mouse chronic social stress model implicates a novel category of candidate genes integrating affective pathogenesis. Progress in Neuro-Psychopharmacology and Biological Psychiatry 105, pages 110086.
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Peter Petschner, Zsofia Gal & Xenia Gonda. 2021. Clinical Bioenergetics. Clinical Bioenergetics 195 221 .
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Shuxia Zhang, Yeru Chen, Yongjie Wang, Piao Zhang, Gang Chen & Youfa Zhou. (2020) Insights Into Translatomics in the Nervous System. Frontiers in Genetics 11.
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Dongping Li, Ying Wang, Xinrong Jin, Die Hu, Chunlei Xia, Hanmei Xu & Jialiang Hu. (2020) NK cell-derived exosomes carry miR-207 and alleviate depression-like symptoms in mice. Journal of Neuroinflammation 17:1.
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Eva O. Melin, Jonatan Dereke & Magnus Hillman. (2020) Low levels of soluble TWEAK, indicating on-going inflammation, were associated with depression in type 1 diabetes: a cross-sectional study. BMC Psychiatry 20:1.
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Marcus Augusto-Oliveira, Gabriela P. Arrifano, Priscila Y. Takeda, Amanda Lopes-Araújo, Leticia Santos-Sacramento, Daniel C. Anthony, Alexei Verkhratsky & Maria Elena Crespo-Lopez. (2020) Astroglia-specific contributions to the regulation of synapses, cognition and behaviour. Neuroscience & Biobehavioral Reviews 118, pages 331-357.
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Sabine Spijker, Maija-Kreetta Koskinen & Danai Riga. (2020) Incubation of depression: ECM assembly and parvalbumin interneurons after stress. Neuroscience & Biobehavioral Reviews 118, pages 65-79.
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Neus Fullana, Júlia Gasull-Camós, Mireia Tarrés-Gatius, Anna Castañé, Analía Bortolozzi & Francesc Artigas. (2020) Astrocyte control of glutamatergic activity: Downstream effects on serotonergic function and emotional behavior. Neuropharmacology 166, pages 107914.
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B. Miterauer & W. Baer. (2020) Disorders of human consciousness in the Tri-partite synapses. Medical Hypotheses 136, pages 109523.
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Jun-Ling Wang & Chao-Jin Xu. (2020) Astrocytes autophagy in aging and neurodegenerative disorders. Biomedicine & Pharmacotherapy 122, pages 109691.
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Peter Illes, Alexei Verkhratsky & Yong Tang. (2020) Pathological ATPergic Signaling in Major Depression and Bipolar Disorder. Frontiers in Molecular Neuroscience 12.
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Luca SteardoJrJr, Renato de Filippis, Elvira Anna Carbone, Cristina Segura-Garcia, Alexei Verkhratsky & Pasquale De Fazio. (2019) Sleep Disturbance in Bipolar Disorder: Neuroglia and Circadian Rhythms. Frontiers in Psychiatry 10.
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M. Neus Fullana, Esther Ruiz‐Bronchal, Albert Ferrés‐Coy, Elena Juárez‐Escoto, Francesc Artigas & Analia Bortolozzi. (2019) Regionally selective knockdown of astroglial glutamate transporters in infralimbic cortex induces a depressive phenotype in mice. Glia 67:6, pages 1122-1137.
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Jahanshir Tavakolizadeh, Kambiz Roshanaei, Arash Salmaninejad, Reza Yari, Javid Sadri Nahand, Hoda Khoshdel Sarkarizi, Seyed Mojtaba Mousavi, Reza Salarinia, Majid Rahmati, Seyed Farshid Mousavi, Ryan Mokhtari & Hamed Mirzaei. (2018) MicroRNAs and exosomes in depression: Potential diagnostic biomarkers. Journal of Cellular Biochemistry 119:5, pages 3783-3797.
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Dan Song, Kangli Ma, Alexei Verkhratsky & Liang Peng. (2018) l-Dopa and Fluoxetine Upregulate Astroglial 5-HT2B Receptors and Ameliorate Depression in Parkinson’s Disease Mice. Neuroglia 1:1, pages 48-62.
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