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Are antidepressants effective? A debate on their efficacy for the treatment of major depression in adults

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Pages 367-374 | Received 01 Nov 2015, Accepted 15 Feb 2016, Published online: 17 Mar 2016

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Brett D.M. Jones, M. Ishrat Husain & Benoit H. Mulsant. (2021) The use of sequential pharmacotherapy for the treatment of acute major depression: a scoping review. Expert Opinion on Pharmacotherapy 22:8, pages 1005-1014.
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Sheng-Min Wang, Changsu Han, Soo-Jung Lee, Tae-Youn Jun, Ashwin A. Patkar, Prakash S. Masand & Chi-Un Pae. (2018) Efficacy of antidepressants: bias in randomized clinical trials and related issues. Expert Review of Clinical Pharmacology 11:1, pages 15-25.
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Minlan Yuan, Biao Yang, Gerson Rothschild, J. John Mann, Larry D. Sanford, Xiangdong Tang, Canhua Huang, Chuang Wang & Wei Zhang. (2023) Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential. Signal Transduction and Targeted Therapy 8:1.
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Wenjie Yun, Kun Liu, Gaoyang Xu, Mengqi Liu, Qianqian Zhu, Hongling Chu, Xu Chen & Haibo Wang. (2023) Triggering factors of major depressive disorder among adolescents in China. Asian Journal of Psychiatry, pages 103737.
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Tom Bschor & Marlene Krabs. (2023) Wie ein möglichst schonendes Absetzen von Antidepressiva gelingt. DNP – Die Neurologie & Psychiatrie 24:3, pages 54-61.
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Anna-Maria Selalmazidou & Tom Bschor. (2023) Depression: Niedrigschwellige Kardinalmaßnahmen als Basis jeder Behandlung. PSYCH up2date 17:02, pages 117-130.
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Holger C. Bringmann, Andreas Michalsen, Michael Jeitler, Christian S. Kessler, Benno Brinkhaus, Stefan Brunnhuber & Peter Sedlmeier. (2022) Meditation‐based lifestyle modification in mild to moderate depression—A randomized controlled trial. Depression and Anxiety 39:5, pages 363-375.
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Olof R. Hjorth, Andreas Frick, Malin Gingnell, Johanna M. Hoppe, Vanda Faria, Sara Hultberg, Iman Alaie, Kristoffer N. T. Månsson, Jörgen Rosén, Margareta Reis, Kurt Wahlstedt, My Jonasson, Mark Lubberink, Gunnar Antoni, Mats Fredrikson & Tomas Furmark. (2021) Expectancy effects on serotonin and dopamine transporters during SSRI treatment of social anxiety disorder: a randomized clinical trial. Translational Psychiatry 11:1.
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Lisa Hullmeine & Tom Bschor. (2021) Pharmakotherapie der Depression – neue Erkenntnisse und neue Strategien. PiD - Psychotherapie im Dialog 22:03, pages 49-53.
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Michael P Hengartner, Simone Amendola, Jakob A Kaminski, Simone Kindler, Tom Bschor & Martin Plöderl. (2021) Suicide risk with selective serotonin reuptake inhibitors and other new-generation antidepressants in adults: a systematic review and meta-analysis of observational studies. Journal of Epidemiology and Community Health 75:6, pages 523-530.
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Holger C. Bringmann, Nicole Bringmann, Michael Jeitler, Stefan Brunnhuber, Andreas Michalsen & Peter Sedlmeier. (2021) Meditation Based Lifestyle Modification (MBLM) in outpatients with mild to moderate depression: A mixed-methods feasibility study. Complementary Therapies in Medicine 56, pages 102598.
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Jakob André Kaminski & Tom Bschor. (2020) Antidepressants and suicidality: A re-analysis of the re-analysis. Journal of Affective Disorders 266, pages 95-99.
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Saptarshi Purkayastha, Siva Abhishek Addepally & Sherri Bucher. (2020) Engagement and Usability of a Cognitive Behavioral Therapy Mobile App Compared With Web-Based Cognitive Behavioral Therapy Among College Students: Randomized Heuristic Trial. JMIR Human Factors 7:1, pages e14146.
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Vincent Hede, Sophie Favre, Jean-Michel Aubry & Hélène Richard-Lepouriel. (2019) Bipolar spectrum disorder: What evidence for pharmacological treatment? A systematic review. Psychiatry Research 282, pages 112627.
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Theodor Lorenzen & Tom Bschor. (2019) Therapie der Depression — vom Gestern zum Morgen. DNP - Der Neurologe & Psychiater 20:6, pages 66-74.
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Marlene Busche & Tom Bschor. (2019) Absetzen von Antidepressiva. NeuroTransmitter 30:12, pages 27-31.
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Charlotte Godfrey Born, Alastair McClelland & Adrian Furnham. (2019) Mental health literacy for autism spectrum disorder and depression. Psychiatry Research 279, pages 272-277.
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Johanna Gehrisch & Tom Bschor. (2018) Lithium zur Behandlung affektiver Erkrankungen. InFo Neurologie & Psychiatrie 20:2, pages 28-34.
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L. Grassi, M.G. Nanni, G. Rodin, M. Li & R. Caruso. (2018) The use of antidepressants in oncology: a review and practical tips for oncologists. Annals of Oncology 29:1, pages 101-111.
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Vanda Faria, Malin Gingnell, Johanna M. Hoppe, Olof Hjorth, Iman Alaie, Andreas Frick, Sara Hultberg, Kurt Wahlstedt, Jonas Engman, Kristoffer N.T. Månsson, Per Carlbring, Gerhard Andersson, Margareta Reis, Elna-Marie Larsson, Mats Fredrikson & Tomas Furmark. (2017) Do You Believe It? Verbal Suggestions Influence the Clinical and Neural Effects of Escitalopram in Social Anxiety Disorder: A Randomized Trial. EBioMedicine 24, pages 179-188.
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Julia Kleeblatt, Felix Betzler, Laura L. Kilarski, Tom Bschor & Stephan Köhler. (2017) Efficacy of off-label augmentation in unipolar depression: A systematic review of the evidence. European Neuropsychopharmacology 27:5, pages 423-441.
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T. Bschor, C. Baethge, C. Hiemke & B. Müller-Oerlinghausen. (2017) Genetische Tests zur Steuerung der Behandlung mit AntidepressivaGenetic tests for controlling treatment with antidepressants. Der Nervenarzt 88:5, pages 495-499.
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Tom Bschor. (2017) Lithium schützt vor Suizid und Selbstschädigung. InFo Neurologie & Psychiatrie 19:4, pages 12-13.
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Sudha Prathikanti, Renee Rivera, Ashly Cochran, Jose Gabriel Tungol, Nima Fayazmanesh & Eva Weinmann. (2017) Treating major depression with yoga: A prospective, randomized, controlled pilot trial. PLOS ONE 12:3, pages e0173869.
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Jenifer A. Murphy, Jerome Sarris & Gerard J. Byrne. (2017) A Review of the Conceptualisation and Risk Factors Associated with Treatment-Resistant Depression. Depression Research and Treatment 2017, pages 1-10.
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