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Expert Review of Neurotherapeutics Volume 16, 2016 - Issue 5
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Drug Profile

New advances in the treatment of generalized anxiety disorder: the multimodal antidepressant vortioxetine

Laura OrsoliniSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK;Villa San Giuseppe Hospital, Hermanas Hospitalarias, Ascoli Piceno, Italy;Polyedra Research Group, Teramo, Italy;Department of Psychiatry and Neuropsychology, University of Maastricht, Maastricht, The Netherlands
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Carmine TomasettiPolyedra Research Group, Teramo, Italy;NHS, Department of Mental Health ASL Teramo, Psychiatric Service of Diagnosis and Treatment, Hospital ‘Maria SS dello Splendore’, Giulianova, Italy;Laboratory of Molecular and Translational Psychiatry, Department of Neuroscience, Reproductive and Odontostomatogical Sciences, University of Naples ‘Federico II’, Napoli, Italy
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Alessandro ValcheraVilla San Giuseppe Hospital, Hermanas Hospitalarias, Ascoli Piceno, Italy;Polyedra Research Group, Teramo, Italy
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Felice IasevoliPolyedra Research Group, Teramo, Italy;Laboratory of Molecular and Translational Psychiatry, Department of Neuroscience, Reproductive and Odontostomatogical Sciences, University of Naples ‘Federico II’, Napoli, Italy
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Elisabetta Filomena BuonaguroPolyedra Research Group, Teramo, Italy;Laboratory of Molecular and Translational Psychiatry, Department of Neuroscience, Reproductive and Odontostomatogical Sciences, University of Naples ‘Federico II’, Napoli, Italy
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Federica VellantePolyedra Research Group, Teramo, Italy;NHS, Department of Mental Health ASL Teramo, Psychiatric Service of Diagnosis and Treatment, Hospital ‘G. Mazzini’, Teramo, Italy;Department of Neuroscience and Imaging, University ‘G. d’Annunzio’, Chieti, Italy
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Michele FornaroPolyedra Research Group, Teramo, Italy;New York Psychiatric Institute, Columbia University, New York, NY, USA
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Annastasia FiengoPolyedra Research Group, Teramo, Italy
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Monica MazzaPolyedra Research Group, Teramo, Italy;Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy
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Roberta VecchiottiVilla San Giuseppe Hospital, Hermanas Hospitalarias, Ascoli Piceno, Italy;Polyedra Research Group, Teramo, Italy;Department of Psychiatry and Neuropsychology, University of Maastricht, Maastricht, The Netherlands
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Giampaolo PernaDepartment of Psychiatry and Neuropsychology, University of Maastricht, Maastricht, The Netherlands;Hermanas Hospitalarias, FoRiPsi, Department of Clinical Neurosciences, Villa San Benedetto Menni, Albese con Cassano, Como, Italy;Department of Psychiatry and Behavioral Sciences, Leonard Miller School of Medicine, University of Miami, Coral Gables, Florida, USA
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Andrea de BartolomeisLaboratory of Molecular and Translational Psychiatry, Department of Neuroscience, Reproductive and Odontostomatogical Sciences, University of Naples ‘Federico II’, Napoli, Italy
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Giovanni MartinottiNew York Psychiatric Institute, Columbia University, New York, NY, USA
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Massimo Di GiannantonioNew York Psychiatric Institute, Columbia University, New York, NY, USA
&
Domenico De BerardisPolyedra Research Group, Teramo, Italy;NHS, Department of Mental Health ASL Teramo, Psychiatric Service of Diagnosis and Treatment, Hospital ‘G. Mazzini’, Teramo, Italy;New York Psychiatric Institute, Columbia University, New York, NY, USACorrespondence[email protected]
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Pages 483-495 | Received 26 Dec 2015, Accepted 30 Mar 2016, Published online: 18 Apr 2016

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Rohini Bose, Syed Usman Hamdani, Fareed Aslam Minhas & Keira Joann Herr. (2022) A comparison of real-world effectiveness of vortioxetine along the treatment algorithm for major depressive disorder. Current Medical Research and Opinion 38:5, pages 661-671.
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Janne Kaergaard Mortensen & Grethe Andersen. (2021) Pharmacological management of post-stroke depression: an update of the evidence and clinical guidance. Expert Opinion on Pharmacotherapy 22:9, pages 1157-1166.
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Felix-Martin Werner & Rafael Coveñas. (2019) Therapeutic Effect of Novel Antidepressant Drugs Acting at Specific Receptors of Neurotransmitters and Neuropeptides. Current Pharmaceutical Design 25:4, pages 388-395.
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Anish Shah & Joanne Northcutt. (2018) An open-label, flexible dose adaptive study evaluating the efficacy of vortioxetine in subjects with panic disorder. Annals of General Psychiatry 17:1.
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Sidney H. Kennedy, Jean-Marie Grouin, Stéphanie Cadour, Véronique Robert & Françoise Picarel-Blanchot. (2018) Relative short-term efficacy and acceptability of agomelatine versus vortioxetine in adult patients suffering from major depressive disorder. Human Psychopharmacology: Clinical and Experimental 33:1, pages e2646.
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Domenico De Berardis, Luigi Olivieri, Francesco Nappi, Gabriella Rapini, Federica Vellante, Ilaria Matarazzo, Nicola Serroni & Massimo Di Giannantonio. (2017) Vortioxetine and Aripiprazole Combination in Treatment-Resistant Obsessive-Compulsive Disorder. Journal of Clinical Psychopharmacology 37:6, pages 732-734.
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