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Neuronal glucose metabolism and schizophrenia: therapeutic prospects?

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Pages 29-40 | Published online: 10 Jan 2014

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Donard S Dwyer, Kathrine Weeks & Eric J Aamodt. (2008) Drug discovery based on genetic and metabolic findings in schizophrenia. Expert Review of Clinical Pharmacology 1:6, pages 773-789.
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Pamela McPherson, Saveen Sall, Aurianna Santos, Willie Thompson & Donard S. Dwyer. (2022) Catalytic Reaction Model of Suicide. Frontiers in Psychiatry 13.
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Abigail I. Nash. (2017) Crosstalk between insulin and dopamine signaling: A basis for the metabolic effects of antipsychotic drugs. Journal of Chemical Neuroanatomy 83-84, pages 59-68.
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Joanne H. Huang, Hyoungjun Park, Jonathan Iaconelli, Shaunna S. Berkovitch, Bradley Watmuff, Donna McPhie, Dost Öngür, Bruce M. Cohen, Clary B. Clish & Rakesh Karmacharya. (2016) Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines. Journal of Proteome Research 16:2, pages 481-493.
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Donard S. Dwyer, Eric Aamodt, Bruce Cohen & Edgar A. Buttner. (2014) Drug elucidation: invertebrate genetics sheds new light on the molecular targets of CNS drugs. Frontiers in Pharmacology 5.
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Kathrine R. Weeks, Donard S. Dwyer & Eric J. Aamodt. (2010) Antipsychotic Drugs Activate the C. elegans Akt Pathway via the DAF-2 Insulin/IGF-1 Receptor . ACS Chemical Neuroscience 1:6, pages 463-473.
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Y. E. Savoy, M. A. Ashton, M. W. Miller, F. M. Nedza, D. K. Spracklin, M. H. Hawthorn, H. Rollema, F. F. Matos & E. Hajos-Korcsok. (2008) Differential Effects of Various Typical and Atypical Antipsychotics on Plasma Glucose and Insulin Levels in the Mouse: Evidence for the Involvement of Sympathetic Regulation. Schizophrenia Bulletin 36:2, pages 410-418.
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Jean-Michel Aubry, Michèle Schwald, Eladia Ballmann & Félicien Karege. (2009) Early effects of mood stabilizers on the Akt/GSK-3β signaling pathway and on cell survival and proliferation. Psychopharmacology 205:3, pages 419-429.
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Jeffrey A. Lieberman, Frank P. Bymaster, Herbert Y. Meltzer, Ariel Y. Deutch, Gary E. Duncan, Christine E. Marx, June R. Aprille, Donard S. Dwyer, Xin-Min Li, Sahebarao P. Mahadik, Ronald S. Duman, Joseph H. Porter, Josephine S. Modica-Napolitano, Samuel S. Newton & John G. Csernansky. (2008) Antipsychotic Drugs: Comparison in Animal Models of Efficacy, Neurotransmitter Regulation, and Neuroprotection. Pharmacological Reviews 60:3, pages 358-403.
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Donard S. Dwyer & Addie Dickson. 2007. The Pharmacology of Neurogenesis and Neuroenhancement. The Pharmacology of Neurogenesis and Neuroenhancement 247 289 .
C. Anthony Altar, Linda W. Jurata, Vin Charles, Andrew Lemire, Peng Liu, Yury Bukhman, Theresa A. Young, Jeff Bullard, Hiroko Yokoe, Maree J. Webster, Michael B. Knable & Jeffrey A. Brockman. (2005) Deficient Hippocampal Neuron Expression of Proteasome, Ubiquitin, and Mitochondrial Genes in Multiple Schizophrenia Cohorts. Biological Psychiatry 58:2, pages 85-96.
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Xiao-Hong Lu, Ronald J Bradley & Donard S Dwyer. (2004) Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38. Brain Research 1011:1, pages 58-68.
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