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Drug Evaluation

Donepezil (Aricept®) for treatment of Alzheimer´s disease and other dementing conditions

Pages 5-16 | Published online: 10 Jan 2014

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Anas Shamsi, Moyad Al Shahwan, Shahzaib Ahamad, Md. Imtaiyaz Hassan, Faizan Ahmad & Asimul Islam. (2020) Spectroscopic, calorimetric and molecular docking insight into the interaction of Alzheimer’s drug donepezil with human transferrin: implications of Alzheimer’s drug. Journal of Biomolecular Structure and Dynamics 38:4, pages 1094-1102.
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Sandra A Jacobson & Marwan N Sabbagh. (2008) Donepezil: potential neuroprotective and disease-modifying effects. Expert Opinion on Drug Metabolism & Toxicology 4:10, pages 1363-1369.
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Abhilash K Desai & George T Grossberg. (2005) Rivastigmine for Alzheimer’s disease. Expert Review of Neurotherapeutics 5:5, pages 563-580.
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B.N. Szafran, G.A. Casillas & B.L. Alman. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 35 51 .
Piotr Londzin, Marcin Trawczyński, Urszula Cegieła, Zenon P. Czuba & Joanna Folwarczna. (2023) Effects of Donepezil on the Musculoskeletal System in Female Rats. International Journal of Molecular Sciences 24:10, pages 8991.
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Jing-Jing Liang, Tian-Ming Lv, Zhi-Yong Xu, Ning-Ning Du, Bin Lin, Xiao-Xiao Huang & Shao-Jiang Song. (2023) Two new iridoids and triterpenoid analogues from the leaves of Viburnum chingii and their anti-acetylcholinesterase activity. Fitoterapia 165, pages 105400.
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Edward D. Huey, John Hardy, Sonja W. Scholz, Bryan J. Traynor & Scott A. Small. 2020. Tasman’s Psychiatry. Tasman’s Psychiatry 1 17 .
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James T. BrewsterIIII, Simone Dell’Acqua, Danny Q. Thach & Jonathan L. Sessler. (2018) Classics in Chemical Neuroscience: Donepezil. ACS Chemical Neuroscience 10:1, pages 155-167.
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Hee Ra Park, Heeeun Lee, Jung-Jin Lee, Nam-Hui Yim, Min-Jung Gu & Jin Yeul Ma. (2017) Protective Effects of Spatholobi Caulis Extract on Neuronal Damage and Focal Ischemic Stroke/Reperfusion Injury. Molecular Neurobiology 55:6, pages 4650-4666.
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Kevin J. Cao, Kristyna M. Elbel, Jessica L. Cifelli, Jordi Cirera, Christina J. Sigurdson, Francesco Paesani, Emmanuel A. Theodorakis & Jerry Yang. (2018) Solvation-Guided Design of Fluorescent Probes for Discrimination of Amyloids. Scientific Reports 8:1.
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Na Shao, Yong-Yang Luo, Hui-Jie Lu, Yuan-Zhao Hua & Min-Can Wang. (2018) Enantioselective phospha-Michael reaction of diethyl phosphonate with exocyclic α,β-unsaturated benzocyclic ketones catalyzed by a dinuclear zinc−AzePhenol catalyst. Tetrahedron 74:17, pages 2130-2142.
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Sotirios Katsamakas & Dimitra Hadjipavlou-Litina. 2019. Multi-Target Drug Design Using Chem-Bioinformatic Approaches. Multi-Target Drug Design Using Chem-Bioinformatic Approaches 203 253 .
Yung-Chih Kuo & Rajendiran Rajesh. (2017) A critical overview of therapeutic strategy and advancement for Alzheimer's disease treatment. Journal of the Taiwan Institute of Chemical Engineers 77, pages 92-105.
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Zhi-qi Mao, Xin-guang Yu, Zhi-pei Ling, Jian-jun Jia, Long-sheng Pan, Xin Xu, Zhi-qiang Cui, Ying Han, Shan-shan Wang & Shu-li Liang. (2017) Deep brain stimulation for treatment of severe Alzheimer's disease: Study protocol for a prospective, self-controlled, phase I trial (case observation). Asia Pacific Journal of Clinical Trials: Nervous System Diseases 2:2, pages 66.
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Yasushi Yabuki, Kazuya Matsuo, Koga Hirano, Yasuharu Shinoda, Shigeki Moriguchi & Kohji Fukunaga. (2017) Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice. Pharmacology 99:3-4, pages 160-171.
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Gary W. Small. (2016) Detection and Prevention of Cognitive Decline. The American Journal of Geriatric Psychiatry 24:12, pages 1142-1150.
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Edward D. Huey, John Hardy & Scott A. Small. 2015. Psychiatry. Psychiatry 398 406 .
Kelsey C. Miles, Chi “Chip” Le & James P. Stambuli. (2014) Direct Carbocyclizations of Benzoic Acids: Catalyst-Controlled Synthesis of Cyclic Ketones and the Development of Tandem aHH (acyl Heck-Heck) Reactions. Chemistry - A European Journal 20:36, pages 11336-11339.
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XUE-QIN HOU, DIAN-WEI WU, CHUN-XIA ZHANG, RONG YAN, CONG YANG, CUI-PING RONG, LEI ZHANG, XIANG CHANG, RU-YU SU, SHI-JIE ZHANG, WEN-QING HE, ZHAO QU, SHI LI, ZI-REN SU, YUN-BO CHEN, QI WANG & SHU-HUAN FANG. (2014) Bushen-Yizhi formula ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in scopolamine-induced senescence in mice. International Journal of Molecular Medicine 34:2, pages 429-439.
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Yang Su, Qiuhong Wang, Changfu Wang, Kelvin Chan, Yanping Sun & Haixue Kuang. (2014) The treatment of Alzheimer's disease using Chinese Medicinal Plants: From disease models to potential clinical applications. Journal of Ethnopharmacology 152:3, pages 403-423.
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Eduardo Luis Konrath, Carolina dos Santos Passos, Luiz Carlos Klein-Júnior & Amélia T Henriques. (2013) Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease. Journal of Pharmacy and Pharmacology 65:12, pages 1701-1725.
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Carolyn W. Zhu, Elayne E. Livote, Nikolaos Scarmeas, Marilyn Albert, Jason Brandt, Deborah Blacker, Mary Sano & Yaakov Stern. (2013) Long‐term associations between cholinesterase inhibitors and memantine use and health outcomes among patients with Alzheimer's disease. Alzheimer's & Dementia 9:6, pages 733-740.
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Soad A Yehia, Ahmed H Elshafeey & Ibrahim Elsayed. (2012) Biodegradable donepezil lipospheres for depot injection: optimization and in-vivo evaluation. Journal of Pharmacy and Pharmacology 64:10, pages 1425-1437.
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Thiago Barth, Raphael Conti, Mônica Tallarico Pupo, Laura Tiemi Okano & Pierina Sueli Bonato. (2012) Chiral HPLC analysis of donepezil, 5-O-desmethyl donepezil and 6-O-desmethyl donepezil in culture medium: application to fungal biotransformation studies. Analytical and Bioanalytical Chemistry 404:1, pages 257-266.
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Luma Nassar-Hardy, Sandy Fabre, Atef M. Amer, Eric Fouquet & François-Xavier Felpin. (2012) Synthesis of indanones by sequential Heck-reduction–cyclization–alkylation (HRCA) reactions. Tetrahedron Letters 53:3, pages 338-341.
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Rüdiger Hardeland. (2011) Cognitive Enhancers in Moderate to Severe Alzheimer's Disease. Clinical Medicine Insights: Therapeutics 3, pages CMT.S6344.
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William D. Kearns, James L. Fozard & Rosemarie S. Lamm. 2011. E-Health, Assistive Technologies and Applications for Assisted Living. E-Health, Assistive Technologies and Applications for Assisted Living 139 160 .
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