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Rosa Tundis, Federica Menichini, Filomena Conforti, Monica R. Loizzo, Marco Bonesi, Giancarlo Statti & Francesco Menichini. (2009) A potential role of alkaloid extracts from Salsola species (Chenopodiaceae) in the treatment of Alzheimer's disease. Journal of Enzyme Inhibition and Medicinal Chemistry 24:3, pages 818-824.
Read now
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Roberta Annicchiarico, Alessia Federici, Carla Pettenati & Carlo Caltagirone. (2007) Rivastigmine in Alzheimer’s disease: Cognitive function and quality of life. Therapeutics and Clinical Risk Management 3:6, pages 1113-1123.
Read now
Read now
Abhilash K Desai & George T Grossberg. (2005) Rivastigmine for Alzheimer’s disease. Expert Review of Neurotherapeutics 5:5, pages 563-580.
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Articles from other publishers (32)
Ozum Ozturk, Fathima Manaal Farouk, Luyi Ooi, Christine Shing Wei Law, Muhammed Tilahun Muhammed, Esin Aki-Yalcin & Keng Yoon Yeong. (2022) Synthesis of novel carboxamide- and carbohydrazide-benzimidazoles as selective butyrylcholinesterase inhibitors. Molecular Diversity 26:5, pages 2863-2876.
Crossref
Crossref
R. S. Remya, N. Ramalakshmi, C.N. Nalini, V. Niraimathi & S. Amuthalakshmi. (2022) Design Synthesis and in vitro Evaluation of Tacrine-flavone Hybrids as
Multifunctional Cholinesterase Inhibitors for Alzheimer’s Disease. Current Computer-Aided Drug Design 18:4, pages 271-292.
Crossref
Crossref
Pedro Brandão, Óscar López, Luisa Leitzbach, Holger Stark, José G. Fernández-Bolaños, Anthony J. Burke & Marta Pineiro. (2021) Ugi Reaction Synthesis of Oxindole–Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors. ACS Medicinal Chemistry Letters 12:11, pages 1718-1725.
Crossref
Crossref
Irene Pachón-Angona, Maciej Maj, Artur Wnorowski, Helene Martin, Krzysztof Jóźwiak & Lhassane Ismaili. (2021)
Synthesis of new Hantzsch adducts showing Ca
2+
channel blockade capacity, cholinesterase inhibition and antioxidant power
. Future Medicinal Chemistry 13:20, pages 1717-1729.
Crossref
Crossref
Majid Balaei-Kahnamoei, Mina Saeedi, Arezoo Rastegari, Mohammad Reza Shams Ardekani, Tahmineh Akbarzadeh & Mahnaz Khanavi. (2021) Phytochemical Analysis and Evaluation of Biological Activity of Lawsonia inermis Seeds Related to Alzheimer’s Disease. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-10.
Crossref
Crossref
Shuaishuai Xing, Qi Li, Baichen Xiong, Yao Chen, Feng Feng, Wenyuan Liu & Haopeng Sun. (2020) Structure and therapeutic uses of butyrylcholinesterase: Application in detoxification, Alzheimer's disease, and fat metabolism. Medicinal Research Reviews 41:2, pages 858-901.
Crossref
Crossref
Shuaishuai Xing, Ying Chen, Baichen Xiong, Weixuan Lu, Qi Li, Yuanyuan Wang, Mengxia Jiao, Feng Feng, Yao Chen, Wenyuan Liu & Haopeng Sun. (2021) Synthesis and bio-evaluation of a novel selective butyrylcholinesterase inhibitor discovered through structure-based virtual screening. International Journal of Biological Macromolecules 166, pages 1352-1364.
Crossref
Crossref
Irene Pachón Angona, Helene Martin, Solene Daniel, Ignacio Moraleda, Alexandre Bonet, Artur Wnorowski, Maciej Maj, Krzysztof Jozwiak, Isabel Iriepa, Bernard Refouvelet, José Marco-Contelles & Lhassane Ismaili. (2020) Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives. International Journal of Molecular Sciences 21:20, pages 7652.
Crossref
Crossref
Weiwei Ma, Jingjing Bi, Chuanfang Zhao, Yangguang Gao & Guisheng Zhang. (2020) Design, synthesis and biological evaluation of acridone glycosides as selective BChE inhibitors. Carbohydrate Research 491, pages 107977.
Crossref
Crossref
Vijay K. Nuthakki, Ramesh Mudududdla, Ankita Sharma, Ajay Kumar & Sandip B. Bharate. (2019) Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors. Bioorganic Chemistry 90, pages 103062.
Crossref
Crossref
Vijay K. Nuthakki, Ankita Sharma, Ajay Kumar & Sandip B. Bharate. (2019)
Identification of embelin, a 3‐undecyl‐1,4‐benzoquinone from
Embelia ribes
as a multitargeted anti‐Alzheimer agent
. Drug Development Research.
Crossref
Crossref
Daniela Volpato & Ulrike Holzgrabe. (2018) Designing Hybrids Targeting the Cholinergic System by Modulating the Muscarinic and Nicotinic Receptors: A Concept to Treat Alzheimer’s Disease. Molecules 23:12, pages 3230.
Crossref
Crossref
Anita Bosak, Alma Ramić, Tamara Šmidlehner, Tomica Hrenar, Ines Primožič & Zrinka Kovarik. (2018) Design and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold. PLOS ONE 13:10, pages e0205193.
Crossref
Crossref
Ludovic Peauger, Rabah Azzouz, Vincent Gembus, Mihaela-Liliana Ţînţaş, Jana Sopková-de Oliveira Santos, Pierre Bohn, Cyril Papamicaël & Vincent Levacher. (2017) Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation. Journal of Medicinal Chemistry 60:13, pages 5909-5926.
Crossref
Crossref
Regina Messerer, Clelia Dallanoce, Carlo Matera, Sarah Wehle, Lisa Flammini, Brian Chirinda, Andreas Bock, Matthias Irmen, Christian Tränkle, Elisabetta Barocelli, Michael Decker, Christoph Sotriffer, Marco De Amici & Ulrike Holzgrabe. (2017)
Novel bipharmacophoric inhibitors of the cholinesterases with affinity to the muscarinic receptors M
1
and M
2
. MedChemComm 8:6, pages 1346-1359.
Crossref
Crossref
Marco Antonio Ceschi, Jessie Sobieski da Costa, João Paulo Bizarro Lopes, Viktor Saraiva Câmara, Leandra Franciscato Campo, Antonio César de Amorim Borges, Carlos Alberto Saraiva Gonçalves, Daniela Fraga de Souza, Eduardo Luis Konrath, Ana Luiza Martins Karl, Isabella Alvim Guedes & Laurent Emmanuel Dardenne. (2016) Novel series of tacrine-tianeptine hybrids: Synthesis, cholinesterase inhibitory activity, S100B secretion and a molecular modeling approach. European Journal of Medicinal Chemistry 121, pages 758-772.
Crossref
Crossref
Jitendra Kumar, Poonam Meena, Anju Singh, Ehtesham Jameel, Mudasir Maqbool, Mohammad Mobashir, Ashutosh Shandilya, Manisha Tiwari, Nasimul Hoda & B. Jayaram. (2016) Synthesis and screening of triazolopyrimidine scaffold as multi-functional agents for Alzheimer's disease therapies. European Journal of Medicinal Chemistry 119, pages 260-277.
Crossref
Crossref
Mohamed Benchekroun, Manuela Bartolini, Javier Egea, Alejandro Romero, Elena Soriano, Marc Pudlo, Vincent Luzet, Vincenza Andrisano, Mar?a-Luisa Jimeno, Manuela G. L?pez, Sarah Wehle, Tijani Gharbi, Bernard Refouvelet, Luc?a de?Andr?s, Clara Herrera-Arozamena, Barbara Monti, Maria Laura Bolognesi, Mar?a Isabel Rodr?guez-Franco, Michael Decker, Jos? Marco-Contelles & Lhassane Ismaili. (2015) Novel Tacrine-Grafted Ugi Adducts as Multipotent Anti-Alzheimer Drugs: A Synthetic Renewal in Tacrine-Ferulic Acid Hybrids. ChemMedChem 10:3, pages 523-539.
Crossref
Crossref
Fouad H. Darras, Beata Kling, Edgar Sawatzky, Jörg Heilmann & Michael Decker. (2014) Cyclic acyl guanidines bearing carbamate moieties allow potent and dirigible cholinesterase inhibition of either acetyl- or butyrylcholinesterase. Bioorganic & Medicinal Chemistry 22:17, pages 5020-5034.
Crossref
Crossref
Jiangke Qin, Wenli Lan, Zhong Liu, Jun Huang, Huang Tang & Hengshan Wang. (2013) Synthesis and biological evaluation of 1, 3-dihydroxyxanthone mannich base derivatives as anticholinesterase agents. Chemistry Central Journal 7:1.
Crossref
Crossref
Ahmadul Kadir, Amelia Marutle, Daniel Gonzalez, Michael Sch?ll, Ove Almkvist, Malahat Mousavi, Tamanna Mustafiz, Taher Darreh-Shori, Inger Nennesmo & Agneta Nordberg. (2011) Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer?s disease. Brain 134:1, pages 301-317.
Crossref
Crossref
Sarfraz A. Nawaz, Muhammad Ayaz, Wolfgang Brandt, Ludger A. Wessjohann & Bernhard Westermann. (2011) Cation–π and π–π stacking interactions allow selective inhibition of butyrylcholinesterase by modified quinine and cinchonidine alkaloids. Biochemical and Biophysical Research Communications 404:4, pages 935-940.
Crossref
Crossref
Stefania Butini, Egeria Guarino, Giuseppe Campiani, Margherita Brindisi, Salvatore Sanna Coccone, Isabella Fiorini, Ettore Novellino, Tatyana Belinskaya, Ashima Saxena & Sandra Gemma. (2008) Tacrine based human cholinesterase inhibitors: Synthesis of peptidic-tethered derivatives and their effect on potency and selectivity. Bioorganic & Medicinal Chemistry Letters 18:19, pages 5213-5216.
Crossref
Crossref
Ernesto Rivera-Becerril, Pedro Joseph-Nathan, Víctor M. Pérez-Álvarez & Martha S. Morales-Ríos. (2008) Synthesis and Biological Evaluation of (−)- and (+)-Debromoflustramine B and Its Analogues as Selective Butyrylcholinesterase Inhibitors. Journal of Medicinal Chemistry 51:17, pages 5271-5284.
Crossref
Crossref
Stefania Butini, Giuseppe Campiani, Marianna Borriello, Sandra Gemma, Alessandro Panico, Marco Persico, Bruno Catalanotti, Sindu Ros, Margherita Brindisi, Marianna Agnusdei, Isabella Fiorini, Vito Nacci, Ettore Novellino, Tatyana Belinskaya, Ashima Saxena & Caterina Fattorusso. (2008) Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors. Journal of Medicinal Chemistry 51:11, pages 3154-3170.
Crossref
Crossref
Roger Lane, Howard H. Feldman, Joanne Meyer, Yunsheng He, Steven H. Ferris, Agneta Nordberg, Taher Darreh-Shori, Hilkka Soininen, Tuula Pirttilä, Martin R. Farlow, Nikolaos Sfikas, Clive Ballard & Nigel H. Greig. (2008) Synergistic effect of apolipoprotein E ε4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease. Pharmacogenetics and Genomics 18:4, pages 289-298.
Crossref
Crossref
Joachim Hartmann, Cornelia Kiewert, Ellen G. Duysen, Oksana Lockridge, Nigel H. Greig & Jochen Klein. (2007) Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity. Journal of Neurochemistry 100:5, pages 1421-1429.
Crossref
Crossref
Elise Rowan, Ian G. McKeith, Brian K. Saxby, John T. O’Brien, David Burn, Urs Mosimann, Jane Newby, Sarah Daniel, Jonathan Sanders & Keith Wesnes. (2007) Effects of Donepezil on Central Processing Speed and Attentional Measures in Parkinson’s Disease with Dementia and Dementia with Lewy Bodies. Dementia and Geriatric Cognitive Disorders 23:3, pages 161-167.
Crossref
Crossref
R. Schliebs & T. Arendt. (2006) The significance of the cholinergic system in the brain during aging and in Alzheimer’s disease. Journal of Neural Transmission 113:11, pages 1625-1644.
Crossref
Crossref
T. Darreh-Shori, S. Brimijoin, A. Kadir, O. Almkvist & A. Nordberg. (2006) Differential CSF butyrylcholinesterase levels in Alzheimer's disease patients with the ApoE ε4 allele, in relation to cognitive function and cerebral glucose metabolism. Neurobiology of Disease 24:2, pages 326-333.
Crossref
Crossref
Edwin H. RydbergBoris BrumshteinHarry M. GreenblattDawn M. WongDavid ShayaLarry D. WilliamsPaul R. CarlierYuan-Ping PangIsrael SilmanJoel L. Sussman. (2006)
Complexes of Alkylene-Linked Tacrine Dimers with
Torpedo c
alifornica
Acetylcholinesterase: Binding of Bis(5)-tacrine Produces a Dramatic Rearrangement in the Active-Site Gorge
. Journal of Medicinal Chemistry 49:18, pages 5491-5500.
Crossref
Crossref
Mohammad A. Kamal, Abdulaziz A. Al-Jafari, Qian-Sheng Yu & Nigel H. Greig. (2006) Kinetic analysis of the inhibition of human butyrylcholinesterase with cymserine. Biochimica et Biophysica Acta (BBA) - General Subjects 1760:2, pages 200-206.
Crossref
Crossref