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Clinical utility and pharmacology of high-dose methotrexate in the treatment of primary CNS lymphoma

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Pages 635-652 | Published online: 10 Jan 2014

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Qing Cong, Ling Lin, Biao Qi, Congjian Xu & Xiaoyan Zhang. (2021) Human Chorionic Gonadotropin Polypeptide Nanoparticle Drug Delivery System Improves Methotrexate Efficacy in Gestational Trophoblastic Neoplasia in vitro. Cancer Management and Research 13, pages 1699-1708.
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Sheng‐Fan Wang, Kuan‐Wei Huang, Yueh‐Ching Chou, Hsin‐Chen Lee, Po‐Kuei Wu, Wei‐Ming Chen, Giun‐Yi Hung & Yuh‐Lih Chang. (2023) Effect of c o‐medications and potential risk factors of high‐dose methotrexate‐mediated acute hepatotoxicity in patients with osteosarcoma . Cancer Medicine 12:11, pages 12354-12364.
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Joseph P. Eder & Navid Hafez. 2017. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine 1 13 .
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Pedro Gustavo Barros Rodrigues, Talles Tavares de Lima, Fernando Barroso Duarte & Paulo Ribeiro Nóbrega. (2022) Myelopathy associated with intrathecal methotrexate. Practical Neurology 22:2, pages 141-144.
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Justine Solignac, Laure Farnault, Thomas Robert, Raphaelle Fanciullino, Sylvain Choquet, Philippe Brunet, Geoffroy Venton & Mickaël Bobot. (2022) Successful treatment with adapted high dose methotrexate in a hemodialysis patient with primary central nervous system lymphoma: 100 mg/m2 seems sufficient. Nefrología (English Edition) 42:2, pages 130-134.
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Justine Solignac, Laure Farnault, Thomas Robert, Raphaelle Fanciullino, Sylvain Choquet, Philippe Brunet, Geoffroy Venton & Mickaël Bobot. (2022) Successful treatment with adapted high dose methotrexate in a hemodialysis patient with primary central nervous system lymphoma: 100 mg/m2 seems sufficient. Nefrología 42:2, pages 130-134.
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Giovanni Di Lorenzo, Giuseppe Mirenda, Serena Springer, Maria Teresa Mirandola, Francesco Paolo Mangino, Federico Romano & Giuseppe Ricci. (2022) Hysteroscopic Treatment of Cervical Pregnancy: A Scoping Review of the Literature. Journal of Minimally Invasive Gynecology 29:3, pages 345-354.e1.
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Jason N. Barreto, Joel M. Reid, Carrie A. Thompson, Kristin C. Mara, Andrew D. Rule, Kianoush B. Kashani, Nelson Leung, Thomas R. Larson, Renee M. McGovern, Thomas E. Witzig & Erin F. Barreto. (2021) Prospective evaluation of high‐dose methotrexate pharmacokinetics in adult patients with lymphoma using novel determinants of kidney function. Clinical and Translational Science 15:1, pages 105-117.
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Andrea Morales-Martinez, Fernando Lozano-Sanchez, Alberto Duran-Peña, Khe Hoang-Xuan & Caroline Houillier. (2021) Primary Central Nervous System Lymphoma in Elderly Patients: Management and Perspectives. Cancers 13:14, pages 3479.
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Catherine E. DeFino, Jason N. Barreto, Amanda G. Pawlenty, Michael W. Ruff, Ivan D. Carabenciov, Kristin C. Mara & Carrie A. Thompson. (2021) Lack of drug interaction between levetiracetam and high‐dose methotrexate in patients with lymphoma. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 41:5, pages 430-439.
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Xiaoli Chang, Yixian Guo, Li Su, Yunxiu Zhang, Wuhan Hui, Hong Zhao, Ronghua Hu & Wanling Sun. (2021) Influence of MTHFR C677T Polymorphism on High-Dose Methotrexate-Related Toxicity in Patients With Primary Central Nervous System Diffuse Large B-Cell Lymphoma. Clinical Lymphoma Myeloma and Leukemia 21:2, pages 91-96.
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Uvette Lou, Jamie Kwok, Thu Anne Nguyen, Allen Zhou & Samantha O. Luk. (2019) Effect of Levetiracetam on Time to High‐Dose Methotrexate Clearance in Patients With Hematologic Malignancies. The Journal of Clinical Pharmacology 60:3, pages 324-330.
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Biljana Škorić, Marija Jovanović, Branislava Miljković, Miloš Kuzmanović & Katarina Vučićević. (2020) Clinical pharmacokinetics of methotrexate in the treatment of acute lymphoblastic leukemia and non-Hodgkin lymphoma in pediatric patients. Arhiv za farmaciju 70:1, pages 20-33.
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William N. Hait & Joseph P. Eder. 2016. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine 1 15 .
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Craig A. Vargo, Leslie A. Ray & Herbert B. Newton. 2018. Cancer Neurology in Clinical Practice. Cancer Neurology in Clinical Practice 275 310 .
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Alessia Dalla Pria, Maggie Bendle, Ramya Ramaswami, Marta Boffito & Mark Bower. (2015) The pharmacokinetics of high-dose methotrexate in people living with HIV on antiretroviral therapy. Cancer Chemotherapy and Pharmacology 77:3, pages 653-657.
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Yedidia Bentur & Yael Lurie. 2016. Critical Care Toxicology. Critical Care Toxicology 1 49 .
S Jabeen, L Holmboe, G I G Alnæs, A M Andersen, K S Hall & V N Kristensen. (2015) Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate. The Pharmacogenomics Journal 15:5, pages 385-390.
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Brigitte C. Widemann, Stefan Schwartz, Nalini Jayaprakash, Robbin Christensen, Ching-Hon Pui, Nikhil Chauhan, Claire Daugherty, Thomas R. King, Janet E. Rush & Scott C. Howard. (2014) Efficacy of Glucarpidase (Carboxypeptidase G2) in Patients with Acute Kidney Injury After High-Dose Methotrexate Therapy. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 34:5, pages 427-439.
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Riccardo Soffietti, Elisa Trevisan & Roberta Rudà. 2014. Neurologic Aspects of Systemic Disease Part III. Neurologic Aspects of Systemic Disease Part III 1199 1218 .
Moon Ki Choi, Eun Suk Kang, Dae Won Kim, Yonug Hyeh Ko, Hyeri Seok, Jin Hong Park, Dae Hee Pyo, Do Hoon Lim, Seok Jin Kim & Won Seog Kim. (2013) Treatment outcome of relapsed/refractory primary central nervous system diffuse large B-cell lymphoma: a single-center experience of autologous stem cell transplantation. International Journal of Hematology 98:3, pages 346-354.
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Nicole Bergner, Ina Monsef, Gerald Illerhaus, Andreas Engert & Nicole Skoetz. (2012) Role of chemotherapy additional to high-dose methotrexate for primary central nervous system lymphoma (PCNSL). Cochrane Database of Systematic Reviews.
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Herbert B. Newton. 2012. Neuro-Oncology Part II. Neuro-Oncology Part II 903 916 .
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Christopher J. Campen, Rebecca L. Tombleson & Myke R. Green. (2010) High-dose chemotherapy with hematopoietic stem cell transplantation for the treatment of primary central nervous system lymphoma. Journal of Neuro-Oncology 101:3, pages 345-355.
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