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Drug Profile

Fampridine-SR for multiple sclerosis and spinal cord injury

Pages 453-461 | Published online: 09 Jan 2014

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Keith C Hayes. (2011) Impact of extended-release dalfampridine on walking ability in patients with multiple sclerosis. Neuropsychiatric Disease and Treatment 7, pages 229-239.
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Shuo Li, Hoai Thi Phuong Dinh, Yukihiro Matsuyama, Kohji Sato & Satoru Yamagishi. (2022) Molecular Mechanisms in the Vascular and Nervous Systems following Traumatic Spinal Cord Injury. Life 13:1, pages 9.
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Maria Thorning, Helle Hvilsted Nielsen, Lars Henrik Frich, Henrik Boye Jensen, Kate Lykke Lambertsen & Anders Holsgaard-Larsen. (2022) Gait quality and function after fampridine treatment in patients with multiple sclerosis – A prospective cohort study. Clinical Biomechanics 100, pages 105826.
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Martin Paredes-Cruz, Israel Grijalva, Yoscelina Estrella Martínez-López, Gabriel Guizar-Sahagún, Eloisa Colín-Ramírez & David Rojano-Mejía. (2022) Functional improvement in individuals with chronic spinal cord injury treated with 4-aminopyridine: A systematic review. Frontiers in Neurology 13.
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Ângela Martins, Débora Gouveia, Ana Cardoso, Carla Carvalho, Tiago Coelho, Cátia Silva, Inês Viegas, Óscar Gamboa & António Ferreira. (2021) A Controlled Clinical Study of Intensive Neurorehabilitation in Post-Surgical Dogs with Severe Acute Intervertebral Disc Extrusion. Animals 11:11, pages 3034.
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Kristen M. Manto, Prem Kumar Govindappa, Daniele Parisi, Zara Karuman, Brandon Martinazzi, John P. Hegarty, M A Hassan Talukder & John C. Elfar. (2021) (4-Aminopyridine)–PLGA–PEG as a Novel Thermosensitive and Locally Injectable Treatment for Acute Peripheral Nerve Injury. ACS Applied Bio Materials 4:5, pages 4140-4151.
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Jhan-Jie Peng, Shih-Han Lin, Yu-Tzu Liu, Hsin-Chieh Lin, Tsai-Ning Li & Chi-Kuang Yao. (2019) A circuit-dependent ROS feedback loop mediates glutamate excitotoxicity to sculpt the Drosophila motor system. eLife 8.
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Michał Piwoński, Klaudia Żak, Patrycja Gierszon, Izabela Morawska, Dominika Psiuk & Agata Stachura. (2019) The Role of Fampridine in the Symptomatic Treatment of Gait Impairment in Patients with Multiple Sclerosis. Acta Balneologica 61:3, pages 199-207.
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Verena Isabell Leussink, Xavier Montalban & Hans-Peter Hartung. (2018) Restoring Axonal Function with 4-Aminopyridine: Clinical Efficacy in Multiple Sclerosis and Beyond. CNS Drugs 32:7, pages 637-651.
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François Jacques, Adrian Schembri, Avi Nativ, Chantal Paquette & Pawel Kalinowski. (2018) Prolonged-Release Fampridine as Adjunct Therapy to Active Motor Training in MS Patients: A Pilot, Double-Blind, Randomized, Placebo-Controlled Study. Multiple Sclerosis Journal - Experimental, Translational and Clinical 4:1, pages 205521731876116.
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Da-Nian Ma, Xia-Qi Zhang, Jie Ying, Zhong-Jun Chen & Li-Xin Li. (2017) Efficacy and safety of 9 nonoperative regimens for the treatment of spinal cord injury. Medicine 96:47, pages e8679.
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Magaly Lecat, Pierre Decavel, Eloi Magnin, Brigitte Lucas, Vincent  Gremeaux & Yoshimasa Sagawa. (2017) Multiple Sclerosis and Clinical Gait Analysis before and after Fampridine: A Systematic Review. European Neurology 78:5-6, pages 272-286.
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Matthew D. Alvin & Michael P. Steinmetz. 2017. Benzel's Spine Surgery, 2-Volume Set. Benzel's Spine Surgery, 2-Volume Set 1217 1230.e4 .
Gerold Ebenbichler & Helmut Kern. 2017. Kompendium Physikalische Medizin und Rehabilitation. Kompendium Physikalische Medizin und Rehabilitation 363 384 .
H.B. Jensen, Sepehr Mamoei, M. Ravnborg, U. Dalgas & E. Stenager. (2016) Distribution-based estimates of minimum clinically important difference in cognition, arm function and lower body function after slow release-fampridine treatment of patients with multiple sclerosis. Multiple Sclerosis and Related Disorders 7, pages 58-60.
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Henrik Boye Jensen, Mads Ravnborg, Ulrik Dalgas & Egon Stenager. (2013) 4-Aminopyridine for symptomatic treatment of multiple sclerosis: a systematic review. Therapeutic Advances in Neurological Disorders 7:2, pages 97-113.
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Jeffrey A. Strommen. (2013) Management of Spasticity from Spinal Cord Dysfunction. Neurologic Clinics 31:1, pages 269-286.
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Gerold Ebenbichler & Helmut Kern. 2013. Kompendium Physikalische Medizin und Rehabilitation. Kompendium Physikalische Medizin und Rehabilitation 421 443 .
Wendy L. Imlach, Erin S. Beck, Ben Jiwon Choi, Francesco Lotti, Livio Pellizzoni & Brian D. McCabe. (2012) SMN Is Required for Sensory-Motor Circuit Function in Drosophila. Cell 151:2, pages 427-439.
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James Guest. 2011. Youmans Neurological Surgery. Youmans Neurological Surgery 2719 2729 .
Jennifer M. Belavic. (2010) Dalfampridine (Ampyra) for multiple sclerosis. The Nurse Practitioner 35:11, pages 7-9.
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Israel Grijalva, Angélica García-Pérez, Jenaro Díaz, Sergio Aguilar, Dolores Mino, Efraín Santiago-Rodríguez, Gabriel Guizar-Sahagún, Gilberto Castañeda-Hernández, Héctor Maldonado-Julián & Ignacio Madrazo. (2010) High Doses of 4-Aminopyridine Improve Functionality in Chronic Complete Spinal Cord Injury Patients with MRI Evidence of Cord Continuity. Archives of Medical Research 41:7, pages 567-575.
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Brian K. KwonJessica HillyerWolfram Tetzlaff. (2010) Translational Research in Spinal Cord Injury: A Survey of Opinion from the SCI Community. Journal of Neurotrauma 27:1, pages 21-33.
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N. J. OLBY, D. T. SMITH, J. HUMPHREY, K. SPINAPOLICE, N. PARKE, P. M. MEHTA, D. DISE & M. PAPICH. (2009) Pharmacokinetics of 4-aminopyridine derivatives in dogs. Journal of Veterinary Pharmacology and Therapeutics 32:5, pages 485-491.
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Ardith M. Courtney, Katherine Treadaway, Gina Remington & Elliot Frohman. (2009) Multiple Sclerosis. Medical Clinics of North America 93:2, pages 451-476.
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Anne R Korenke, Michael P Rivey & Douglas R Allington. (2008) Sustained-Release Fampridine for Symptomatic Treatment of Multiple Sclerosis. Annals of Pharmacotherapy 42:10, pages 1458-1465.
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Robert L. Ruff, Lisa McKerracher & Michael E. Selzer. (2008) Repair and Neurorehabilitation Strategies for Spinal Cord Injury. Annals of the New York Academy of Sciences 1142:1, pages 1-20.
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