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Expert Review of Neurotherapeutics Volume 7, 2007 - Issue 5
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Review

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?

Rudy J Castellani University of Maryland, Department of Pathology, 22 South Greene Street, Baltimore, MD, 21201, USA. [email protected]
,
Xiongwei Zhu Case Western Reserve University, Department of Pathology, Cleveland, OH USA. [email protected]
,
Hyoung-gon Lee Case Western Reserve University, Department of Pathology, Cleveland, OH USA. [email protected]
,
Paula I Moreira University of Coimbra, Center for Neuroscience and Cell Biology of Coimbra, Coimbra, Portugal. [email protected]
,
George Perry Case Western Reserve University, Department of Pathology, Cleveland, Ohio USA; College of Sciences, University of Texas, San Antonio, San Antonia, TX, USA. [email protected]
&
Mark A Smith Case Western Reserve University, Department of Pathology, 2103 Cornell Road, Cleveland, OH 44106 USA. [email protected]
Pages 473-485 | Published online: 09 Jan 2014

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Wei-Na Yang, Xiao-Dan Hu, Hua Han, Li-Li Shi, Gai-Feng Feng, Yong Liu & Yi-Hua Qian. (2014) The effects of valsartan on cognitive deficits induced by aluminum trichloride and d-galactose in mice. Neurological Research 36:7, pages 651-658.
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Diego Muñoz-Torrero & Pelayo Camps. (2008) Huprines for Alzheimer's disease drug development. Expert Opinion on Drug Discovery 3:1, pages 65-81.
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Brian Spencer, Edward Rockenstein, Leslie Crews, Robert Marr & Eliezer Masliah. (2007) Novel strategies for Alzheimer's disease treatment. Expert Opinion on Biological Therapy 7:12, pages 1853-1867.
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Paula van Tijn, Willem Kamphuis, Michael W. Marlatt, Elly M. Hol & Paul J. Lucassen. (2011) Presenilin mouse and zebrafish models for dementia: Focus on neurogenesis. Progress in Neurobiology 93:2, pages 149-164.
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P Calissano, G Amadoro, C Matrone, S Ciafrè, R Marolda, V Corsetti, M T Ciotti, D Mercanti, A Di Luzio, C Severini, C Provenzano & N Canu. (2010) Does the term ‘trophic’ actually mean anti-amyloidogenic? The case of NGF. Cell Death & Differentiation 17:7, pages 1126-1133.
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Henryk Faas, Walker S Jackson, Andrew W. Borkowski, Xinhe Wang, Jiyan Ma, Susan Lindquist & Alan Jasanoff. (2010) Context-dependent perturbation of neural systems in transgenic mice expressing a cytosolic prion protein. NeuroImage 49:3, pages 2607-2617.
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John D. Furber. 2010. The Future of Aging. The Future of Aging 587 621 .
Marie-Christine Pardon, Sarir Sarmad, Ivan Rattray, Timothy E. Bates, Gillian A. Scullion, Charles A. Marsden, David A. Barrett, James Lowe & David A. Kendall. (2009) Repeated novel cage exposure-induced improvement of early Alzheimer's-like cognitive and amyloid changes in TASTPM mice is unrelated to changes in brain endocannabinoids levels. Neurobiology of Aging 30:7, pages 1099-1113.
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Haigang Gu, Dahong Long, Cunxian Song & Xiaobin Li. (2009) Recombinant human NGF-loaded microspheres promote survival of basal forebrain cholinergic neurons and improve memory impairments of spatial learning in the rat model of Alzheimer's disease with fimbria-fornix lesion. Neuroscience Letters 453:3, pages 204-209.
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E. Kvam & A. Messer. 2009. Handbook of Neurochemistry and Molecular Neurobiology. Handbook of Neurochemistry and Molecular Neurobiology 459 470 .
Diane B. Miller & James P. O'Callaghan. (2008) Do early-life insults contribute to the late-life development of Parkinson and Alzheimer diseases?. Metabolism 57, pages S44-S49.
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Andréa C LeBlanc. (2008) Introspective analysis of amyloid as the cause of Alzheimer’s disease: alternative model proposed. Future Neurology 3:5, pages 527-536.
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Zhi-zhong GUAN. (2008) Cross-talk between oxidative stress and modifications of cholinergic and glutaminergic receptors in the pathogenesis of Alzheimer's disease 1 . Acta Pharmacologica Sinica 29:7, pages 773-780.
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Rudy J. Castellani, Hyoung-gon Lee, Xiongwei Zhu, George Perry & Mark A. Smith. (2008) Alzheimer Disease Pathology As a Host Response. Journal of Neuropathology & Experimental Neurology 67:6, pages 523-531.
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Lawrence M. Sayre, George Perry & Mark A. Smith. (2007) Oxidative Stress and Neurotoxicity. Chemical Research in Toxicology 21:1, pages 172-188.
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Bogdan O. Popescu. (2007) Still debating a cause and diagnostic criteria for Alzheimer's disease. Journal of Cellular and Molecular Medicine 11:6, pages 1225-1226.
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