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Special Report

Cannabinoids as potential new therapy for the treatment of gliomas

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Pages 37-49 | Published online: 09 Jan 2014

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Dolores Hernán Pérez de la Ossa, Maria Esther Gil-Alegre, Alessia Ligresti, María del Rosario Aberturas, Jesús Molpeceres, Ana Isabel Torres & Vincenzo Di Marzo. (2013) Preparation and characterization of Δ9-tetrahydrocannabinol-loaded biodegradable polymeric microparticles and their antitumoral efficacy on cancer cell lines. Journal of Drug Targeting 21:8, pages 710-718.
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Anna Maria Malfitano, Elena Ciaglia, Giuseppina Gangemi, Patrizia Gazzerro, Chiara Laezza & Maurizio Bifulco. (2011) Update on the endocannabinoid system as an anticancer target. Expert Opinion on Therapeutic Targets 15:3, pages 297-308.
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Articles from other publishers (23)

Martin Helcman & Karel Šmejkal. (2021) Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases. Phytochemistry Reviews 21:2, pages 429-470.
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Reyaz Hassan, Roohi Mohi-ud-din, Mohammad Ovais Dar, Abdul Jalil Shah, Prince Ahad Mir, Majeed Shaikh & Faheem Hyder Pottoo. (2022) Bioactive Heterocyclic Compounds as Potential Therapeutics in the Treatment of Gliomas: A Review. Anti-Cancer Agents in Medicinal Chemistry 22:3, pages 551-565.
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Shahinda S. R. Alsayed, Amreena Suri, Anders W. Bailey, Samuel Lane, Eryn L. Werry, Chiang-Ching Huang, Li-Fang Yu, Michael Kassiou, Simone Treiger Sredni & Hendra Gunosewoyo. (2021) Synthesis and antitumour evaluation of indole-2-carboxamides against paediatric brain cancer cells. RSC Medicinal Chemistry 12:11, pages 1910-1925.
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Patrícia Alves, Cristina Amaral, Natércia Teixeira & Georgina Correia-da-Silva. (2020) Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol. Pharmacological Research 157, pages 104822.
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Martina Winklmayr, Martin Gaisberger, Michael Kittl, Julia Fuchs, Markus Ritter & Martin Jakab. (2019) Dose‐Dependent Cannabidiol‐Induced Elevation of Intracellular Calcium and Apoptosis in Human Articular Chondrocytes. Journal of Orthopaedic Research 37:12, pages 2540-2549.
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Alsalem, Altarifi, Haddad, Aldossary, Kalbouneh, Aldaoud, Saleh & El-Salem. (2019) Antinociceptive and Abuse Potential Effects of Cannabinoid/Opioid Combinations in a Chronic Pain Model in Rats. Brain Sciences 9:11, pages 328.
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Ana Gabriela Silva, Caio Fabio Baeta Lopes, Clóvis Gomes Carvalho Júnior, Ralph Gruppi Thomé, Hélio Batista dos Santos, Rui Reis & Rosy Iara Maciel de Azambuja Ribeiro. (2019) WIN55,212-2 induces caspase-independent apoptosis on human glioblastoma cells by regulating HSP70, p53 and Cathepsin D. Toxicology in Vitro 57, pages 233-243.
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Tim Hohmann, Kerstin Feese, Thomas Greither, Chalid Ghadban, Vivian Jäger, Faramarz Dehghani & Urszula Grabiec. (2019) Synthetic Cannabinoids Influence the Invasion of Glioblastoma Cell Lines in a Cell- and Receptor-Dependent Manner.. Cancers 11:2, pages 161.
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Eric P. Baron. (2018) Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. Headache: The Journal of Head and Face Pain 58:7, pages 1139-1186.
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Simona Pisanti, Anna Maria Malfitano, Elena Ciaglia, Anna Lamberti, Roberta Ranieri, Gaia Cuomo, Mario Abate, Giorgio Faggiana, Maria Chiara Proto, Donatella Fiore, Chiara Laezza & Maurizio Bifulco. (2017) Cannabidiol: State of the art and new challenges for therapeutic applications. Pharmacology & Therapeutics 175, pages 133-150.
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Repossi Gastón, Pasqualini María Eugenia, Undurti N. Das & Aldo R. Eynard. (2017) Polyunsaturated Fatty Acids Differentially Modulate Cell Proliferation and Endocannabinoid System in Two Human Cancer Lines. Archives of Medical Research 48:1, pages 46-54.
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Oier Aizpurua-Olaizola, Umut Soydaner, Ekin Öztürk, Daniele Schibano, Yilmaz Simsir, Patricia Navarro, Nestor Etxebarria & Aresatz Usobiaga. (2016) Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes . Journal of Natural Products 79:2, pages 324-331.
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Katia Wehbe, Isabelle Forfar, Sandrine Eimer & Gianfelice Cinque. (2015) Discrimination between two different grades of human glioma based on blood vessel infrared spectral imaging. Analytical and Bioanalytical Chemistry 407:24, pages 7295-7305.
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Ken Yasukawa. (2014) Cannabinoids as seed compounds for the cancer treatment. Forensic Toxicology 32:2, pages 189-193.
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Javier Fernández-Ruiz, Mariluz Hernández & Yolanda García-Movellán. 2014. Cannabinoids. Cannabinoids 175 218 .
Morgan A. Marks, Anil K. Chaturvedi, Karl Kelsey, Kurt Straif, Julien Berthiller, Stephen M. Schwartz, Elaine Smith, Annah Wyss, Paul Brennan, Andrew F. Olshan, Qingyi Wei, Erich M. Sturgis, Zuo-Feng Zhang, Hal Morgenstern, Joshua Muscat, Philip Lazarus, Michael McClean, Chu Chen, Thomas L. Vaughan, Victor Wunsch-Filho, Maria Paula Curado, Sergio Koifman, Elena Matos, Ana Menezes, Alexander W. Daudt, Leticia Fernandez, Marshall Posner, Paolo Boffetta, Yuan-Chin Amy Lee, Mia Hashibe & Gypsyamber D'Souza. (2014) Association of Marijuana Smoking with Oropharyngeal and Oral Tongue Cancers: Pooled Analysis from the INHANCE Consortium. Cancer Epidemiology, Biomarkers & Prevention 23:1, pages 160-171.
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Steven N. Gurley, Ammaar H. Abidi, Patrick Allison, Peihong Guan, Christopher Duntsch, Jon H. Robertson, Stanley D. Kosanke, Stephen T. Keir, Darell D. Bigner, Andrea J. Elberger & Bob M. MooreIIII. (2012) Mechanism of anti-glioma activity and in vivo efficacy of the cannabinoid ligand KM-233. Journal of Neuro-Oncology 110:2, pages 163-177.
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Ethan B Russo. (2011) Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology 163:7, pages 1344-1364.
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E. Zurolo, A.M. Iyer, W.G.M. Spliet, P.C. Van Rijen, D. Troost, J.A. Gorter & E. Aronica. (2010) CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologies. Neuroscience 170:1, pages 28-41.
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Susanne Oesch & Jürg Gertsch. (2009) Cannabinoid receptor ligands as potential anticancer agents — high hopes for new therapies?. Journal of Pharmacy and Pharmacology 61:7, pages 839-853.
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Jahan P. Marcu, Rigel T. Christian, Darryl Lau, Anne J. Zielinski, Maxx P. Horowitz, Jasmine Lee, Arash Pakdel, Juanita Allison, Chandani Limbad, Dan H. Moore, Garret L. Yount, Pierre-Yves Desprez & Sean D. McAllister. (2010) Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival. Molecular Cancer Therapeutics 9:1, pages 180-189.
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Caihua Liang, Michael D. McClean, Carmen Marsit, Brock Christensen, Edward Peters, Heather H. Nelson & Karl T. Kelsey. (2009) A Population-Based Case-Control Study of Marijuana Use and Head and Neck Squamous Cell Carcinoma. Cancer Prevention Research 2:8, pages 759-768.
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Alphi Elackattu & Scharukh Jalisi. (2009) Living with Head and Neck Cancer and Coping with Dying when Treatments Fail. Otolaryngologic Clinics of North America 42:1, pages 171-184.
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