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Expert Review of Neurotherapeutics Volume 8, 2008 - Issue 11
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Editorial

γ-secretase modulators: hopes and setbacks for the future of Alzheimer’s treatment

Genevieve Evin Department of Pathology, The University of Melbourne, Parkville, VIC 3010, Australia. [email protected]
Pages 1611-1613 | Published online: 09 Jan 2014

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Taisuke Tomita. (2009) Secretase inhibitors and modulators for Alzheimer’s disease treatment. Expert Review of Neurotherapeutics 9:5, pages 661-679.
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Articles from other publishers (5)

Maria Z. Kounnas, Murat S. Durakoglugil, Joachim Herz & William T. Comer. (2019) NGP 555, a γ‐secretase modulator, shows a beneficial shift in the ratio of amyloid biomarkers in human cerebrospinal fluid at safe doses. Alzheimer's & Dementia: Translational Research & Clinical Interventions 5:1, pages 458-467.
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Maria Z. Kounnas, Courtney Lane-Donovan, Dan W. Nowakowski, Joachim Herz & William T. Comer. (2017) NGP 555, a γ-secretase modulator, lowers the amyloid biomarker, Aβ 42, in cerebrospinal fluid while preventing Alzheimer's disease cognitive decline in rodents . Alzheimer's & Dementia: Translational Research & Clinical Interventions 3:1, pages 65-73.
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Christian Fischer, Sanjiv Shah, Bethany L. Hughes, George N. Nikov, Jamie L. Crispino, Richard E. Middleton, Alexander A. Szewczak, Benito Munoz & Mark S. Shearman. (2011) Quinazolinones as ?-secretase modulators. Bioorganic & Medicinal Chemistry Letters 21:2, pages 773-776.
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Laura J. Klesse & Daniel C. Bowers. (2010) Childhood Medulloblastoma. CNS Drugs 24:4, pages 285-301.
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Bruno A Bergmans & Bart De Strooper. (2010) γ-secretases: from cell biology to therapeutic strategies. The Lancet Neurology 9:2, pages 215-226.
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