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Drug Profile

Escitalopram for the treatment of major depression and anxiety disorders

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Pages 537-552 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Kaida Jiang, Lingjiang Li, Xueyi Wang, Maosheng Fang, Jianfei Shi, Qiuyun Cao, Jincai He, Jinan Wang, Weihao Tan & Cuili Hu. (2017) Efficacy and tolerability of escitalopram in treatment of major depressive disorder with anxiety symptoms: a 24-week, open-label, prospective study in Chinese population. Neuropsychiatric Disease and Treatment 13, pages 515-526.
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Bernardo Dell’Osso, Chiara Arici, Cristina Dobrea, Giulia Camuri, Beatrice Benatti & A Carlo Altamura. (2013) Escitalopram tolerability as mono- versus augmentative therapy in patients with affective disorders: a naturalistic study. Neuropsychiatric Disease and Treatment 9, pages 205-209.
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Nedim Havle, Yavuz Altunkaynak, Cengiz Dayan, M. Cem İlnem & Baki Arpacı. (2010) İnme Sonrası Depresyon Tedavisinde Essitalopram. Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology 20:1, pages 74-78.
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Articles from other publishers (33)

Kazi Ishtiak-AhmedKatherine L. MuslinerKaj Sparle ChristensenErik Lykke MortensenAndrew A. NierenbergChristiane Gasse. (2023) Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark. American Journal of Psychiatry.
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Tian-Shun Shi, Wei-Yu Li, Yan-Mei Chen, Jie Huang, Wei Guan, Da-Wei Xu & Bo Jiang. (2023) The antidepressant-like effects of escitalopram in mice require salt-inducible kinase 1 and CREB-regulated transcription co-activator 1 in the paraventricular nucleus of the hypothalamus. Journal of Affective Disorders 338, pages 228-238.
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Raju Bandu, Hyun Jeong Lee, Hyeong Min Lee, Tae Hyon Ha, Heon-Jeong Lee, Se Joo Kim, Kyooseob Ha & Kwang Pyo Kim. (2023) Association between Plasma Metabolic Profiles of the Antidepressant Escitalopram and Clinical Response in Subjects with Depression. Mass Spectrometry 12:1, pages A0123-A0123.
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Chiging Sonia, Th.Gomti Devi & T. Karlo. (2023) Quantum chemical analysis and spectroscopic characterization of Escitalopram. Materials Today: Proceedings.
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Li-Jeng Chen, Tsai-Ching Hsu, Hsiang-Lin Chan, Chiao-Fan Lin, Jing-Yu Huang, Robert Stewart, Bor-Show Tzang & Vincent Chin-Hung Chen. (2022) Protective Effect of Escitalopram on Hepatocellular Carcinoma by Inducing Autophagy. International Journal of Molecular Sciences 23:16, pages 9247.
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Caroline W. Espinola, Yuelee Khoo, Roohie Parmar, Ilya Demchenko, Benicio N. Frey, Roumen V. Milev, Arun V. Ravindran, Sagar V. Parikh, Keith Ho, Susan Rotzinger, Wendy Lou, Raymond W. Lam, Sidney H. Kennedy & Venkat Bhat. (2022) Pretreatment anxious depression as a predictor of side effect frequency and severity in escitalopram and aripiprazole adjunctive therapy. Brain and Behavior 12:5.
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Or Burstein, Noam Simon, Yaarit Simchon-Tenenbaum, Moshe Rehavi, Motty Franko, Alon Shamir & Ravid Doron. (2021) Moderation of the transgenerational transference of antenatal stress-induced anxiety. Translational Psychiatry 11:1.
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Ji-hua Xu & Peng Jiang. (2018) Efficacy of escitalopram oxalate for patients with post-stroke depression. Medicine 97:14, pages e0219.
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Vincent Chin-Hung Chen, Yi-Hsien Hsieh, Li-Jeng Chen, Tsai-Ching Hsu & Bor-Show Tzang. (2017) Escitalopram oxalate induces apoptosis in U-87MG cells and autophagy in GBM8401 cells. Journal of Cellular and Molecular Medicine.
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Han Sol KimHongliang LiHye Won KimSung Eun ShinMi Seon SeoJin Ryeol AnKwon-Soo HaEun-Taek HanSeok-Ho HongIl-Whan ChoiGrace ChoiDae-sung LeeWon Sun Park. (2017) Escitalopram, a selective serotonin reuptake inhibitor, inhibits voltage-dependent K + channels in coronary arterial smooth muscle cells . The Korean Journal of Physiology & Pharmacology 21:4, pages 415.
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Brian M. Ross, Imran Malik & Slim Babay. (2016) Dietary omega-3 polyunsaturated fatty acid supplementation in an animal model of anxiety. Prostaglandins, Leukotrienes and Essential Fatty Acids 114, pages 17-20.
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Yingli Zhang, Guoping Huang, Shichang Yang, Wei Liang, Lei Zhang & Changhong Wang. (2016) Duloxetine in treating generalized anxiety disorder in adults: A meta-analysis of published randomized, double-blind, placebo-controlled trials. Asia-Pacific Psychiatry 8:3, pages 215-225.
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Christian Schmidt, Judith Leibiger & Markus Fendt. (2016) The norepinephrine reuptake inhibitor reboxetine is more potent in treating murine narcoleptic episodes than the serotonin reuptake inhibitor escitalopram. Behavioural Brain Research 308, pages 205-210.
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Yun-Ai Su, Ji-Tao Li, Wen-Ji Dai, Xue-Mei Liao, Li-Cai Dong, Tian-Lan Lu, Chad Bousman & Tian-Mei Si. (2016) Genetic variation in the tryptophan hydroxylase 2 gene moderates depressive symptom trajectories and remission over 8 weeks of escitalopram treatment. International Clinical Psychopharmacology 31:3, pages 127-133.
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Cristina Benatti, Silvia Alboni, Joan M.C. Blom, Francesco Gandolfi, Julien Mendlewicz, Nicoletta Brunello & Fabio Tascedda. (2014) Behavioural and transcriptional effects of escitalopram in the chronic escape deficit model of depression. Behavioural Brain Research 272, pages 121-130.
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Yong-Gu Kim, Hun-Soo Chang, Eun-Soo Won, Byung-Joo Ham & Min-Soo Lee. (2014) Serotonin-Related Polymorphisms in TPH1 and HTR5A Genes Are Not Associated with Escitalopram Treatment Response in Korean Patients with Major Depression. Neuropsychobiology 69:4, pages 210-219.
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Caroline T. Nguyen, Michael I. MacEntee, Barbara Mintzes & Thomas L. Perry. (2013) Information for Physicians and Pharmacists About Drugs That Might Cause Dry Mouth: A Study of Monographs and Published Literature. Drugs & Aging 31:1, pages 55-65.
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Michael Sonntag, Hans-Helmut König & Alexander Konnopka. (2013) The Estimation of Utility Weights in Cost-Utility Analysis for Mental Disorders: A Systematic Review. PharmacoEconomics 31:12, pages 1131-1154.
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Luciane Costa-Campos, Ana P. Herrmann, Luísa K. Pilz, Marcus Michels, Guilherme Noetzold & Elaine Elisabetsky. (2013) Interactive effects of N-acetylcysteine and antidepressants. Progress in Neuro-Psychopharmacology and Biological Psychiatry 44, pages 125-130.
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M. Häring, M. Grieb, K. Monory, B. Lutz & F.A. Moreira. (2013) Cannabinoid CB1 receptor in the modulation of stress coping behavior in mice: The role of serotonin and different forebrain neuronal subpopulations. Neuropharmacology 65, pages 83-89.
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H.-J. Möller, I. Bitter, J. Bobes, K. Fountoulakis, C. Höschl & S. Kasper. (2020) Position statement of the European Psychiatric Association (EPA) on the value of antidepressants in the treatment of unipolar depression. European Psychiatry 27:2, pages 114-128.
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Charles D. Ciccone. 2012. Geriatric Physical Therapy. Geriatric Physical Therapy 38 63 .
Thierno Madjou Bah, Mohamed Benderdour, Sévan Kaloustian, Ramy Karam, Guy Rousseau & Roger Godbout. (2011) Escitalopram reduces circulating pro-inflammatory cytokines and improves depressive behavior without affecting sleep in a rat model of post-cardiac infarct depression. Behavioural Brain Research 225:1, pages 243-251.
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Y-M Chen, X-M Huang, R Thompson & Y-B Zhao. (2011) Clinical Features and Efficacy of Escitalopram Treatment for Geriatric Depression. Journal of International Medical Research 39:5, pages 1946-1953.
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L. Asensi-Bernardi, Y. Martín-Biosca, M.J. Medina-Hernández & S. Sagrado. (2011) On the zopiclone enantioselective binding to human albumin and plasma proteins. An electrokinetic chromatography approach. Journal of Chromatography A 1218:20, pages 3111-3117.
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Shawn D. Youngstedt, Christopher E. Kline, Jay P. Ginsberg, Mark R. Zielinski & James W. Hardin. (2011) Bright light treatment for high-anxious young adults: a randomized controlled pilot study. Depression and Anxiety 28:4, pages 324-332.
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Andréa D.E. Zomkowski, Daiane Engel, Nelson H. Gabilan & Ana Lúcia S. Rodrigues. (2010) Involvement of NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test. European Neuropsychopharmacology 20:11, pages 793-801.
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Ramadhan Oruch, Anders Lund, Ian F. Pryme & Holm Holmsen. (2010) An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?. Journal of Chemical Biology 3:2, pages 67-88.
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Brian M. Ross. (2009) Omega-3 polyunsaturated fatty acids and anxiety disorders. Prostaglandins, Leukotrienes and Essential Fatty Acids 81:5-6, pages 309-312.
Crossref
Ju Seok Ryu, Sook Joung Lee, In Young Sung Tae Sung Ko & Han Ik Yoo. (2009) Depressive Episode With Catatonic Features in a Case of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS). Journal of Child Neurology 24:10, pages 1307-1309.
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Winson Y. Cheung, Lisa W. Le & Camilla Zimmermann. (2009) Symptom clusters in patients with advanced cancers. Supportive Care in Cancer 17:9, pages 1223-1230.
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Mark J. Millan. (2009) Dual- and triple-acting agents for treating core and co-morbid symptoms of major depression: novel concepts, new drugs. Neurotherapeutics 6:1, pages 53-77.
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Sefi KronenbergAmos Frisch, Beni Rotberg, Miri Carmel, Alan ApterAbraham Weizman. (2008) Pharmacogenetics of selective serotonin reuptake inhibitors in pediatric depression and anxiety. Pharmacogenomics 9:11, pages 1725-1736.
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