78
Views
64
CrossRef citations to date
0
Altmetric
Review

Survey of human-use adjuvants

Pages 167-188 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Sarah Gordon, Katherine Young, Rachel Wilson, Shakila Rizwan, Roslyn Kemp, Thomas Rades & Sarah Hook. (2012) Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research 22:3, pages 193-204.
Read now
Antu K Dey & Indresh K Srivastava. (2011) Novel adjuvants and delivery systems for enhancing immune responses induced by immunogens. Expert Review of Vaccines 10:2, pages 227-251.
Read now
Sue D Xiang, Karen Scalzo-Inguanti, Gabriela Minigo, Anthony Park, Charles L Hardy & Magdalena Plebanski. (2008) Promising particle-based vaccines in cancer therapy. Expert Review of Vaccines 7:7, pages 1103-1119.
Read now
Dorothea Sesardic, Sjoerd Rijpkema & Brijesh Prakash Patel. (2007) New adjuvants: EU regulatory developments. Expert Review of Vaccines 6:5, pages 849-861.
Read now
Pieranna Chiarella, Emanuela Massi, Mariangela De Robertis, Emanuela Signori & Vito Michele Fazio. (2007) Adjuvants in vaccines and for immunisation: current trends. Expert Opinion on Biological Therapy 7:10, pages 1551-1562.
Read now
Szilvia Mosolits, Bo Nilsson & Håkan Mellstedt. (2005) Towards therapeutic vaccines for colorectal carcinoma: a review of clinical trials. Expert Review of Vaccines 4:3, pages 329-350.
Read now
Jeffrey B Ulmer. (2004) Enhancement of vaccine potency through improved delivery. Expert Opinion on Biological Therapy 4:7, pages 1045-1051.
Read now

Articles from other publishers (57)

Najwa Ahmad Zamri, Muhammad Ehsan Fitri Rusli, Loqman Mohamad Yusof & Rozita Rosli. (2022) Immunization with a bicistronic DNA vaccine modulates systemic IFN-γ and IL-10 expression against Vibrio cholerae infection. Journal of Medical Microbiology 71:5.
Crossref
Sumira Malik, Shristi Kishore, Shradha A. Kumar, Anjali Kumari, Manisha Kumari & Archna Dhasmana. 2022. Handbook of Research on Nanoemulsion Applications in Agriculture, Food, Health, and Biomedical Sciences. Handbook of Research on Nanoemulsion Applications in Agriculture, Food, Health, and Biomedical Sciences 494 516 .
Davood Anvari, Fatemeh Rezaei, Alireza Ashouri, Saeed Rezaei, Hamidreza Majidiani, Abdol Sattar Pagheh, Fatemeh Rezaei, Seyyed Ali Shariatzadeh, Amir Fotovati, Abolghasem Siyadatpanah, Shirzad Gholami & Ehsan Ahmadpour. (2020) Current situation and future prospects of Echinococcus granulosus vaccine candidates: A systematic review . Transboundary and Emerging Diseases 68:3, pages 1080-1096.
Crossref
Deepak Kumar Goyal, Poonam Keshav & Sukhbir Kaur. (2021) Immune induction by adjuvanted Leishmania donovani vaccines against the visceral leishmaniasis in BALB/c mice. Immunobiology 226:2, pages 152057.
Crossref
Deepak Kumar Goyal, Poonam Keshav & Sukhbir Kaur. (2021) Adjuvanted vaccines driven protection against visceral infection in BALB/c mice by Leishmania donovani. Microbial Pathogenesis 151, pages 104733.
Crossref
Fabiana Mahylowski Rinaldi, Emanuelle Baldo Gaspar, Luciana Tendolini Brito & Elizabeth De Gaspari. (2021) Immunogenicity of antigens from outer membrane vesicles of Neisseria meningitidis associated with bilayer fragment of dioctadecyldimethylammonium in Swiss adult mice . Clinical and Experimental Vaccine Research 10:2, pages 106.
Crossref
Xiupeng Wang, Shu Ihara, Xia Li, Atsuo Ito, Yu Sogo, Yohei Watanabe, Noriko M. Tsuji & Atsushi Yamazaki. (2019) Si-doping increases the adjuvant activity of hydroxyapatite nanorods. Colloids and Surfaces B: Biointerfaces 174, pages 300-307.
Crossref
Jin Chen, Xiaoming Yu, Qisheng Zheng, Liting Hou, Luping Du, Yuanpeng Zhang, Xuwen Qiao, Jibo Hou & Kehe Huang. (2018) The immunopotentiator CVC1302 enhances immune efficacy and protective ability of foot-and-mouth disease virus vaccine in pigs. Vaccine 36:52, pages 7929-7935.
Crossref
Xia Li, Xiupeng Wang & Atsuo Ito. (2018) Tailoring inorganic nanoadjuvants towards next-generation vaccines. Chemical Society Reviews 47:13, pages 4954-4980.
Crossref
Ravendra Garg, Lorne Babiuk, Sylvia van Drunen Littel-van den Hurk & Volker Gerdts. (2017) A novel combination adjuvant platform for human and animal vaccines. Vaccine 35:35, pages 4486-4489.
Crossref
Aubrey Davis, Lauren T. Crum, Lynette B. Corbeil & Mark Hildebrand. (2017) Expression of Histophilus somni IbpA DR2 protective antigen in the diatom Thalassiosira pseudonana. Applied Microbiology and Biotechnology 101:13, pages 5313-5324.
Crossref
Alicia M. Schwartz, Michelle Y. Chan, Dawn M. Fedor, Sandra J. Sivananthan & Ryan M. Kramer. 2017. Vaccine Adjuvants. Vaccine Adjuvants 273 283 .
Xiupeng Wang, Xia Li, Atsuo Ito, Yohei Watanabe, Yu Sogo, Motohiro Hirose, Tadao Ohno & Noriko M. Tsuji. (2016) Rod-shaped and substituted hydroxyapatite nanoparticles stimulating type 1 and 2 cytokine secretion. Colloids and Surfaces B: Biointerfaces 139, pages 10-16.
Crossref
Xiupeng Wang, Xia Li, Atsuo Ito, Yohei Watanabe, Yu Sogo, Noriko M. Tsuji & Tadao Ohno. (2016) Stimulation of In Vivo Antitumor Immunity with Hollow Mesoporous Silica Nanospheres. Angewandte Chemie International Edition 55:5, pages 1899-1903.
Crossref
Xiupeng Wang, Xia Li, Atsuo Ito, Yohei Watanabe, Yu Sogo, Noriko M. Tsuji & Tadao Ohno. (2016) Stimulation of In Vivo Antitumor Immunity with Hollow Mesoporous Silica Nanospheres. Angewandte Chemie 128:5, pages 1931-1935.
Crossref
Oscar B. Torres, Carl R. Alving, Arthur E. Jacobson, Kenner C. Rice & Gary R. Matyas. 2016. Biologics to Treat Substance Use Disorders. Biologics to Treat Substance Use Disorders 397 424 .
Sharan Bobbala, Arlene McDowell & Sarah Hook. (2015) Quantitation of the immunological adjuvants, monophosphoryl lipid A and Quil A in poly (lactic-co-glycolic acid) nanoparticles using high performance liquid chromatography with evaporative light scattering detection. Journal of Chromatography B 975, pages 45-51.
Crossref
Huadong Wang, Yanfeng Yao, Chaoyang Huang, Xingxing Fu, Quanjiao Chen, Hongbo Zhang, Jianjun Chen, Fang Fang, Zhenyuan Xie & Ze Chen. (2014) An adjuvanted inactivated murine cytomegalovirus (MCMV) vaccine induces potent and long-term protective immunity against a lethal challenge with virulent MCMV. BMC Infectious Diseases 14:1.
Crossref
Syed Muaz Khalil, Daniel R. Tonkin, Andrew T. Snead, Griffith D. Parks, Robert E. Johnston & Laura J. White. (2014) An Alphavirus-Based Adjuvant Enhances Serum and Mucosal Antibodies, T Cells, and Protective Immunity to Influenza Virus in Neonatal Mice. Journal of Virology 88:16, pages 9182-9196.
Crossref
Jong-Jin Kim, Yun-Ho Hwang, Kyung-Yun Kang, Inbo Kim, Jong-Bae Kim, Jong-Hwan Park, Yung-Choon Yoo & Sung-Tae Yee. (2014) Enhanced dendritic cell maturation by the B-chain of Korean mistletoe lectin (KML-B), a novel TLR4 agonist. International Immunopharmacology 21:2, pages 309-319.
Crossref
Xiupeng Wang, Xia Li, Atsuo Ito, Yu Sogo & Tadao Ohno. (2013) Pore size‐dependent immunogenic activity of mesoporous silica‐based adjuvants in cancer immunotherapy. Journal of Biomedical Materials Research Part A 102:4, pages 967-974.
Crossref
Jong-Jin KimJoung-Pyo NamJae-Woon NahMi-Kyeong JangSung-Tae Yee. (2014) Immunoadjuvant Efficacy of N -Carboxymethyl Chitosan for Vaccination via Dendritic Cell Activation . Journal of Medicinal Food 17:2, pages 268-277.
Crossref
Xiupeng Wang, Ayako Oyane & Atsuo Ito. 2014. Advances in Calcium Phosphate Biomaterials. Advances in Calcium Phosphate Biomaterials 171 197 .
Rajesh K. Gupta. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 32 .
Xiupeng Wang, Xia Li, Atsuo Ito, Yu Sogo & Tadao Ohno. (2013) Particle-size-dependent toxicity and immunogenic activity of mesoporous silica-based adjuvants for tumor immunotherapy. Acta Biomaterialia 9:7, pages 7480-7489.
Crossref
Ankur Singh, Pallab Pradhan & Krishnendu Roy. 2013. Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines. Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines 161 181 .
O. Pérez, A. Batista-Duharte, E. González, C. Zayas, J. Balboa, M. Cuello, O. Cabrera, M. Lastre & V.E.J.C. Schijns. (2012) Human prophylactic vaccine adjuvants and their determinant role in new vaccine formulations. Brazilian Journal of Medical and Biological Research 45:8, pages 681-692.
Crossref
Joshua M. Mutiso, John C. Macharia, Evans Taracha, Kellern Wafula, Hitler Rikoi & Michael M. Gicheru. (2012) Safety and skin delayed-type hypersensitivity response in vervet monkeys immunized with Leishmania donovani sonicate antigen delivered with adjuvants. Revista do Instituto de Medicina Tropical de São Paulo 54:1, pages 37-41.
Crossref
Eder Lilia Romero & Maria Jose Morilla. (2011) Topical and mucosal liposomes for vaccine delivery. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 3:4, pages 356-375.
Crossref
Niranjan Kanesa-thasanAlan Shaw, Jeffrey J. StoddardThomas M. Vernon. (2011) Ensuring the Optimal Safety of Licensed Vaccines: A Perspective of the Vaccine Research, Development, and Manufacturing Companies. Pediatrics 127:Supplement_1, pages S16-S22.
Crossref
Mangala Rao, Kristina K. Peachman, Qin Li, Gary R. Matyas, Sathish B. Shivachandra, Richard Borschel, Venee I. Morthole, Carmen Fernandez-Prada, Carl R. Alving & Venigalla B. Rao. (2011) Highly effective generic adjuvant systems for orphan or poverty-related vaccines. Vaccine 29:5, pages 873-877.
Crossref
Helen C. Koenig, Andrea Sutherland, Hector S. Izurieta & Dennis McGonagle. (2011) Application of the immunological disease continuum to study autoimmune and other inflammatory events after vaccination. Vaccine 29:5, pages 913-919.
Crossref
Sarah Gordon, Elena Teichmann, Katherine Young, Kim Finnie, Thomas Rades & Sarah Hook. (2010) In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery. European Journal of Pharmaceutical Sciences 41:2, pages 360-368.
Crossref
Daniel E. Speiser & Pedro Romero. (2010) Molecularly defined vaccines for cancer immunotherapy, and protective T cell immunity. Seminars in Immunology 22:3, pages 144-154.
Crossref
Joshua M. Mutiso, John C. Macharia, Rosemary M. Mutisya & Evans Taracha. (2010) Subcutaneous immunization against Leishmania major - infection in mice: efficacy of formalin-killed promastigotes combined with adjuvants. Revista do Instituto de Medicina Tropical de São Paulo 52:2, pages 95-100.
Crossref
R. N. COLER, D. CARTER, M. FRIEDE & S. G. REED. (2009) Adjuvants for malaria vaccines. Parasite Immunology 31:9, pages 520-528.
Crossref
Xiaoming Song, Liming Zang & Songhua Hu. (2009) Amplified immune response by ginsenoside-based nanoparticles (ginsomes). Vaccine 27:17, pages 2306-2311.
Crossref
T. A. Olafsdottir, K. Lingnau, E. Nagy & I. Jonsdottir. (2009) IC31 ® , a Two-Component Novel Adjuvant Mixed with a Conjugate Vaccine Enhances Protective Immunity against Pneumococcal Disease in Neonatal Mice . Scandinavian Journal of Immunology 69:3, pages 194-202.
Crossref
Steven G. Reed, Sylvie Bertholet, Rhea N. Coler & Martin Friede. (2009) New horizons in adjuvants for vaccine development. Trends in Immunology 30:1, pages 23-32.
Crossref
Min LiDa-Hai YuHong Cai. (2008) The Synthetic Antimicrobial Peptide KLKL 5 KLK Enhances the Protection and Efficacy of the Combined DNA Vaccine against Mycobacterium tuberculosis . DNA and Cell Biology 27:8, pages 405-413.
Crossref
Gunilla B. Karlsson Hedestam, Ron A.M. Fouchier, Sanjay Phogat, Dennis R. Burton, Joseph Sodroski & Richard T. Wyatt. (2008) The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus. Nature Reviews Microbiology 6:2, pages 143-155.
Crossref
Kerrilyn R. Diener, Lachlan M. Moldenhauer, A. Bruce Lyons, Michael P. Brown & John D. Hayball. (2008) Human Flt-3 ligand-mobilized dendritic cells require additional activation to drive effective immune responses. Experimental Hematology 36:1, pages 51-60.
Crossref
Graham PawelecDietmar Herndler-Brandstetter & Beatrix Grubeck-Loebenstein. 2007. Immunosenescence. Immunosenescence 106 120 .
Paola Rizza, Imerio Capone & Filippo Belardelli. 2007. The Biology of Dendritic Cells and HIV Infection. The Biology of Dendritic Cells and HIV Infection 171 202 .
Martha Kalkanidis, Geoffrey A. Pietersz, Sue D. Xiang, Patricia L. Mottram, Blessing Crimeen-Irwin, Katie Ardipradja & Magdalena Plebanski. (2006) Methods for nano-particle based vaccine formulation and evaluation of their immunogenicity. Methods 40:1, pages 20-29.
Crossref
J. Paul Zoeteweij, Diane E. Epperson, Jackie D. Porter, Chen X. Zhang, Olga Y. Frolova, Anita P. Constantinides, Steven R. Fuhrmann, Moustapha El-Amine, Jing-Hui Tian, Larry R. Ellingsworth & Gregory M. Glenn. (2006) GM1 Binding-Deficient Exotoxin Is a Potent Noninflammatory Broad Spectrum Intradermal Immunoadjuvant. The Journal of Immunology 177:2, pages 1197-1207.
Crossref
O. T. Bühler, C. A. Wiedig, Y. Schmid, G. A. Grassl, E. Bohn & I. B. Autenrieth. (2006) The Yersinia enterocolitica Invasin Protein Promotes Major Histocompatibility Complex Class I- and Class II-Restricted T-Cell Responses . Infection and Immunity 74:7, pages 4322-4329.
Crossref
Carola Schellack, Karin Prinz, Alena Egyed, Jörg H. Fritz, Barbara Wittmann, Michael Ginzler, Gabriele Swatosch, Wolfgang Zauner, Constantia Kast, Shizuo Akira, Alexander von Gabain, Michael Buschle & Karen Lingnau. (2006) IC31, a novel adjuvant signaling via TLR9, induces potent cellular and humoral immune responses. Vaccine 24:26, pages 5461-5472.
Crossref
Raymond H. See, Alexander N. Zakhartchouk, Martin Petric, David J. Lawrence, Catherine P. Y. Mok, Robert J. Hogan, Thomas Rowe, Lois A. Zitzow, Karuna P. Karunakaran, Mary M. Hitt, Frank L. Graham, Ludvik Prevec, James B. Mahony, Chetna Sharon, Thierry C. Auperin, James M. Rini, Aubrey J. Tingle, David W. Scheifele, Danuta M. Skowronski, David M. Patrick, Thomas G. Voss, Lorne A. Babiuk, Jack Gauldie, Rachel L. Roper, Robert C. Brunham & B. Brett Finlay. (2006) Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. Journal of General Virology 87:3, pages 641-650.
Crossref
Elizabeth M. Sutkowski & Marion F. Gruber. 2006. Immunopotentiators in Modern Vaccines. Immunopotentiators in Modern Vaccines 343 359 .
G. M. Glenn & R. T. Kenney. 2006. Mass Vaccination: Global Aspects — Progress and Obstacles. Mass Vaccination: Global Aspects — Progress and Obstacles 247 268 .
Vasee S. Moorthy & Filip Dubovsky. 2005. Molecular Approaches to Malaria. Molecular Approaches to Malaria 480 497 .
Sarah A. Frech, Richard T. Kenney, Christian A. Spyr, Hedvika Lazar, Jean-François Viret, Christian Herzog, Reinhard Glück & Gregory M. Glenn. (2005) Improved immune responses to influenza vaccination in the elderly using an immunostimulant patch. Vaccine 23:7, pages 946-950.
Crossref
Kellathur N. Srinivasan, Vladimir Brusic & Thomas J. August. (2004) New technologies for vaccine development. Drug Development Research 62:4, pages 383-392.
Crossref
B. Brett Finlay, Raymond H. See & Robert C. Brunham. (2004) Rapid response research to emerging infectious diseases: lessons from SARS. Nature Reviews Microbiology 2:7, pages 602-607.
Crossref
Yoshiki Kuroda, Dina C Nacionales, Jun Akaogi, Westley H Reeves & Minoru Satoh. (2004) Autoimmunity induced by adjuvant hydrocarbon oil components of vaccine. Biomedicine & Pharmacotherapy 58:5, pages 325-337.
Crossref
Gregory M Glenn, Richard T Kenney, Scott A Hammond & Larry R Ellingsworth. (2003) Transcutaneous immunization and immunostimulant strategies. Immunology and Allergy Clinics of North America 23:4, pages 787-813.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.