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Review

Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA

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Pages 205-217 | Published online: 09 Jan 2014

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Hidekazu Shirota & Dennis M Klinman. (2014) Recent progress concerning CpG DNA and its use as a vaccine adjuvant. Expert Review of Vaccines 13:2, pages 299-312.
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Ali M Harandi, Gwyn Davies & Ole F Olesen. (2009) Vaccine adjuvants: scientific challenges and strategic initiatives. Expert Review of Vaccines 8:3, pages 293-298.
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Mansour Mohamadzadeh, Tri Duong, Timothy Hoover & Todd R Klaenhammer. (2008) Targeting mucosal dendritic cells with microbial antigens from probiotic lactic acid bacteria. Expert Review of Vaccines 7:2, pages 163-174.
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Rui Tada, Daisuke Yamanaka, Miki Ogasawara, Momoko Saito, Naohito Ohno, Hiroshi Kiyono, Jun Kunisawa & Yukihiko Aramaki. (2018) Polymeric Caffeic Acid Is a Safer Mucosal Adjuvant That Augments Antigen-Specific Mucosal and Systemic Immune Responses in Mice. Molecular Pharmaceutics 15:9, pages 4226-4234.
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Xianliang Ji, Zhiguang Ren, Na Xu, Lingnan Meng, Zhijun Yu, Na Feng, Xiaoyu Sang, Shengnan Li, Yuanguo Li, Tiecheng Wang, Yongkun Zhao, Hualei Wang, Xuexing Zheng, Hongli Jin, Nan Li, Songtao Yang, Jinshan Cao, Wensen Liu, Yuwei Gao & Xianzhu Xia. (2016) Intranasal Immunization with Influenza Virus-Like Particles Containing Membrane-Anchored Cholera Toxin B or Ricin Toxin B Enhances Adaptive Immune Responses and Protection against an Antigenically Distinct Virus. Viruses 8:4, pages 115.
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Rui Tada, Akira Hidaka, Naoko Iwase, Saeko Takahashi, Yuki Yamakita, Tomoko Iwata, Shoko Muto, Emi Sato, Noriko Takayama, Emi Honjo, Hiroshi Kiyono, Jun Kunisawa & Yukihiko Aramaki. (2015) Intranasal Immunization with DOTAP Cationic Liposomes Combined with DC-Cholesterol Induces Potent Antigen-Specific Mucosal and Systemic Immune Responses in Mice. PLOS ONE 10:10, pages e0139785.
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Jinyoung Lee, Jong-Kyun Yoo, Hae-Jin Sohn, Hee-kyoung Kang, Daesik Kim, Ho-Joon Shin & Jong-Hyun Kim. (2015) Protective immunity against Naegleria fowleri infection on mice immunized with the rNfa1 protein using mucosal adjuvants. Parasitology Research 114:4, pages 1377-1385.
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Jitinder S. Wilkhu & Yvonne Perrie. 2015. Subunit Vaccine Delivery. Subunit Vaccine Delivery 95 123 .
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Chunfeng Guan, Jing Ji, Chao Jin, Gang Wang, Xiaozhou Li & Wenzhu Guan. (2014) Expression of cholera toxin B subunit-lumbrokinase in edible sunflower seeds-the use of transmucosal carrier to enhance its fusion protein's effect on protection of rats and mice against thrombosis. Biotechnology Progress 30:5, pages 1029-1039.
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Guan Chunfeng, Li Xiaozhou, Wang Gang, Ji Jing, Jin Chao & Tchouopou Lontchi Josine. (2012) Expression of Cholera Toxin B–Lumbrokinase Fusion Protein in Pichia pastoris—The Use of Transmucosal Carriers in the Delivery of Therapeutic Proteins to Protect Rats Against Thrombosis. Applied Biochemistry and Biotechnology 169:2, pages 636-650.
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Jitinder Wilkhu, Sarah E McNeil, Daniel J Kirby & Yvonne Perrie. (2011) Formulation design considerations for oral vaccines. Therapeutic Delivery 2:9, pages 1141-1164.
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MR Popoff. (2011) Multifaceted interactions of bacterial toxins with the gastrointestinal mucosa. Future Microbiology 6:7, pages 763-797.
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Lissette S. Velasquez, Samantha Shira, Alice N. Berta, Jacquelyn Kilbourne, Babu M. Medi, Ian Tizard, Yawei Ni, Charles J. Arntzen & Melissa M. Herbst-Kralovetz. (2011) Intranasal delivery of Norwalk virus-like particles formulated in an in situ gelling, dry powder vaccine. Vaccine 29:32, pages 5221-5231.
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Nguyen-Xuan Huy, Moon-Sik Yang & Tae-Geum Kim. (2010) Expression of a Cholera Toxin B Subunit-Neutralizing Epitope of the Porcine Epidemic Diarrhea Virus Fusion Gene in Transgenic Lettuce (Lactuca sativa L.). Molecular Biotechnology 48:3, pages 201-209.
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Ali M. Harandi, Donata Medaglini & Robin J. Shattock. (2010) Vaccine adjuvants: A priority for vaccine research. Vaccine 28:12, pages 2363-2366.
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Edmund J. Gosselin, Constantine Bitsaktsis, Ying Li & Bibiana V. Iglesias. (2009) Fc receptor-targeted mucosal vaccination as a novel strategy for the generation of enhanced immunity against mucosal and non-mucosal pathogens. Archivum Immunologiae et Therapiae Experimentalis 57:5, pages 311-323.
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Caleb G. Chen, Yen-Ta Lu, Marie Lin, Natalia Savelyeva, Freda K. Stevenson & Delin Zhu. (2009) Amplification of immune responses against a DNA-delivered idiotypic lymphoma antigen by fusion to the B subunit of E. coli heat labile toxin. Vaccine 27:32, pages 4289-4296.
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Annemarie Hasselberg, Karin Schön, Andrej Tarkowski & Nils Lycke. (2009) Role of CTA1R7K-COL-DD as a novel therapeutic mucosal tolerance-inducing vector for treatment of collagen-induced arthritis. Arthritis & Rheumatism 60:6, pages 1672-1682.
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Constantine Bitsaktsis, Deepak B. Rawool, Ying Li, Nitin V. Kurkure, Bibiana Iglesias & Edmund J. Gosselin. (2009) Differential Requirements for Protection against Mucosal Challenge with Francisella tularensis in the Presence versus Absence of Cholera Toxin B and Inactivated F. tularensis . The Journal of Immunology 182:8, pages 4899-4909.
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Tae-Bin Won, Song-Hua Quan, Dong-Young Kim, Chae-Seo Rhee & Chul Hee Lee. (2009) Immunostimulatory sequence oligdeoxynucleotide/cholera toxin B conjugate: a novel allergen-independent intranasal vaccine for allergic rhinitis. Annals of Allergy, Asthma & Immunology 102:4, pages 314-322.
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