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Novel approaches in polyepitope T-cell vaccine development against HIV-1

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Sergei I. Bazhan, Denis V. Antonets, Ekaterina V. Starostina, Tatyana N. Ilyicheva, Olga N. Kaplina, Vasiliy Yu. Marchenko, Olga Yu. Volkova, Anastasiya Yu. Bakulina & Larisa I. Karpenko. (2022) In silico design of influenza a virus artificial epitope-based T-cell antigens and the evaluation of their immunogenicity in mice. Journal of Biomolecular Structure and Dynamics 40:7, pages 3196-3212.
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Kimia Kardani, Azam Bolhassani & Ali Namvar. (2020) An overview of in silico vaccine design against different pathogens and cancer. Expert Review of Vaccines 19:8, pages 699-726.
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Sayuri Seki & Tetsuro Matano. (2016) Development of a Sendai virus vector-based AIDS vaccine inducing T cell responses. Expert Review of Vaccines 15:1, pages 119-127.
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Alberto Fernández-Tejada, Barton F Haynes & Samuel J Danishefsky. (2015) Designing synthetic vaccines for HIV. Expert Review of Vaccines 14:6, pages 815-831.
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Alena Y Reguzova, Larisa I Karpenko, Ludmila V Mechetina & Igor M Belyakov. (2015) Peptide–MHC multimer-based monitoring of CD8 T-cells in HIV-1 infection and AIDS vaccine development. Expert Review of Vaccines 14:1, pages 69-84.
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Articles from other publishers (16)

Laura Matarazzo & Paulo J. G. Bettencourt. (2023) mRNA vaccines: a new opportunity for malaria, tuberculosis and HIV. Frontiers in Immunology 14.
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Iñaki Bastida & Alberto Fernández-Tejada. (2020) Synthetic carbohydrate-based HIV-1 vaccines. Drug Discovery Today: Technologies 35-36, pages 45-56.
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Maryam Ebrahimi, Seyyed Javad Seyyedtabaei, Mohammad Mehdi Ranjbar, Farid Tahvildar-biderouni & Amirreza Javadi Mamaghani. (2019) Designing and Modeling of Multi-epitope Proteins for Diagnosis of Toxocara canis Infection. International Journal of Peptide Research and Therapeutics 26:3, pages 1371-1380.
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Armina Alagheband Bahrami, Mojgan Bandehpour, Bahman Khalesi & Bahram Kazemi. (2019) Computational Design and Analysis of a Poly-Epitope Fusion Protein: A New Vaccine Candidate for Hepatitis and Poliovirus. International Journal of Peptide Research and Therapeutics 26:1, pages 389-403.
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Fatemeh Namazi, Azam Bolhassani, Seyed Mehdi Sadat & Shiva Irani. (2020) Delivery of HIV-1 Polyepitope Constructs Using Cationic and Amphipathic Cell Penetrating Peptides into Mammalian Cells. Current HIV Research 17:6, pages 408-428.
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Andrey P. Rudometov, Anton N. Chikaev, Nadezhda B. Rudometova, Denis V. Antonets, Alexander A. Lomzov, Olga N. Kaplina, Alexander A. Ilyichev & Larisa I. Karpenko. (2019) Artificial Anti-HIV-1 Immunogen Comprising Epitopes of Broadly Neutralizing Antibodies 2F5, 10E8, and a Peptide Mimic of VRC01 Discontinuous Epitope. Vaccines 7:3, pages 83.
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Sergei I. Bazhan, Denis V. Antonets, Larisa I. Karpenko, Svetlana F. Oreshkova, Olga N. Kaplina, Ekaterina V. Starostina, Sergei G. Dudko, Sofia A. Fedotova & Alexander A. Ilyichev. (2019) In silico Designed Ebola Virus T-Cell Multi-Epitope DNA Vaccine Constructions Are Immunogenic in Mice. Vaccines 7:2, pages 34.
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Larisa I. Karpenko, Sergei I. Bazhan, Alexey M. Eroshkin, Denis V. Antonets, Anton N. Chikaev & Alexander A. Ilyichev. 2018. Advances in HIV and AIDS Control. Advances in HIV and AIDS Control.
Hassan Elsayed, Ghulam Nabi, William J. McKinstry, Keith K. Khoo, Johnson Mak, Andres M. Salazar, Matthias Tenbusch, Vladimir Temchura & Klaus Überla. (2018) Intrastructural Help: Harnessing T Helper Cells Induced by Licensed Vaccines for Improvement of HIV Env Antibody Responses to Virus-Like Particle Vaccines. Journal of Virology 92:14.
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Ehsan Ollah Jazaeri, Atiyeh Mahdavi & Asghar Abdoli. (2017) Formulation of chitosan with the polyepitope HIV-1 protein candidate vaccine efficiently boosts cellular immune responses in mice. Pathogens and Disease 75:8.
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Irina V. Medvedeva, Pavel S. Demenkov & Vladimir A. Ivanisenko. (2017) SITEX 2.0: Projections of protein functional sites on eukaryotic genes. Extension with orthologous genes. Journal of Bioinformatics and Computational Biology 15:02, pages 1650044.
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Lei Tan, Yuqiang Zhang, Fang Liu, Yanmei Yuan, Yuan Zhan, Yingjie Sun, Xusheng Qiu, Chunchun Meng, Cuiping Song & Chan Ding. (2016) Infectious bronchitis virus poly-epitope-based vaccine protects chickens from acute infection. Vaccine 34:44, pages 5209-5216.
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L. I. Karpenko, S. I. Bazhan, M. P. Bogryantseva, N. N. Ryndyuk, Z. I. Ginko, V. I. Kuzubov, L. R. Lebedev, O. N. Kaplina, A. Yu. Reguzova, A. B. Ryzhikov, S. V. Usova, S. F. Oreshkova, E. A. Nechaeva, E. D. Danilenko & A. A. Ilyichev. (2016) Results of phase I clinical trials of a combined vaccine against HIV-1 based on synthetic polyepitope immunogens. Russian Journal of Bioorganic Chemistry 42:2, pages 170-182.
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S. Herath, A. Le Heron, S. Colloca, P. Bergin, S. Patterson, J. Weber, R. Tatoud & G. Dickson. (2015) Analysis of T cell responses to chimpanzee adenovirus vectors encoding HIV gag–pol–nef antigen. Vaccine 33:51, pages 7283-7289.
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Alena Reguzova, Denis Antonets, Larisa Karpenko, Alexander Ilyichev, Rinat Maksyutov & Sergei Bazhan. (2015) Design and Evaluation of Optimized Artificial HIV-1 Poly-T Cell-Epitope Immunogens. PLOS ONE 10:3, pages e0116412.
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Leonard Moise, Frances Terry, Andres H. Gutierrez, Ryan Tassone, Phyllis Losikoff, Stephen H. Gregory, Chris Bailey-Kellogg, William D. Martin & Anne S. De Groot. (2014) Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection. Frontiers in Microbiology 5.
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