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Identifying vaccine targets for anti-leishmanial vaccine development

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Beatriz Coutinho De Oliveira, Malcolm S. Duthie & Valéria Rêgo Alves Pereira. (2020) Vaccines for leishmaniasis and the implications of their development for American tegumentary leishmaniasis. Human Vaccines & Immunotherapeutics 16:4, pages 919-930.
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Shyam Sundar, Neha Agrawal & Bhawana Singh. (2019) Exploiting knowledge on pharmacodynamics-pharmacokinetics for accelerated anti-leishmanial drug discovery/development. Expert Opinion on Drug Metabolism & Toxicology 15:7, pages 595-612.
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Shyam Sundar & Bhawana Singh. (2018) Understanding Leishmania parasites through proteomics and implications for the clinic. Expert Review of Proteomics 15:5, pages 371-390.
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Salvador Iborra, José Carlos Solana, José María Requena & Manuel Soto. (2018) Vaccine candidates against leishmania under current research. Expert Review of Vaccines 17:4, pages 323-334.
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Articles from other publishers (37)

Ganesh Yadagiri, Aakriti Singh, Kanika Arora & Shyam Lal Mudavath. (2023) Immunotherapy and immunochemotherapy in combating visceral leishmaniasis. Frontiers in Medicine 10.
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Olayinka Osuolale. 2023. Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges. Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges 235 261 .
Munawwar Karim, Garima Singh, Shweta Thakur, Aarti Rana, Abdur Rub & Yusuf Akhter. (2022) Evaluating complete surface-associated and secretory proteome of Leishmania donovani for discovering novel vaccines and diagnostic targets. Archives of Microbiology 204:10.
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Alessandra Campbell Pinheiro & Marcus Vinícius Nora de Souza. (2022) Current leishmaniasis drug discovery. RSC Medicinal Chemistry 13:9, pages 1029-1043.
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María José Germanó, Juan Pablo Mackern-Oberti, Jessica Gardone Vitório, Mariana Costa Duarte, Daniel Carvalho Pimenta, Maria Victoria Sanchez, Flavia Alejandra Bruna, Esteban Sebastián Lozano, Ana Paula Fernandes & Diego Esteban Cargnelutti. (2022) Identification of Immunodominant Antigens From a First-Generation Vaccine Against Cutaneous Leishmaniasis. Frontiers in Immunology 13.
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Deep Chandra Balodi, Apeksha Anand, Karthik Ramalingam, Shailendra Yadav & Neena Goyal. (2022) Dipeptidylcarboxypeptidase of Leishmania donovani: A potential vaccine molecule against experimental visceral leishmaniasis. Cellular Immunology 375, pages 104529.
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Anurag Kumar, Prajakta Nimsarkar & Shailza Singh. (2022) Probing the Interactions Responsible for the Structural Stability of Trypanothione Reductase Through Computer Simulation and Biophysical Characterization. The Protein Journal 41:2, pages 230-244.
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Rohit Sharma, Francys Avendaño Rangel, João Luís Reis-Cunha, Larissa Pinheiro Marques, Claudio P. Figueira, Pedro B. Borba, Sayonara M. Viana, Tom Beneke, Daniella C. Bartholomeu & Camila I. de Oliveira. (2022) Targeted Deletion of Centrin in Leishmania braziliensis Using CRISPR-Cas9-Based Editing. Frontiers in Cellular and Infection Microbiology 11.
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Apeksha Anand, Deep Chandra Balodi, Karthik Ramalingam, Shailendra Yadav & Neena Goyal. (2022) Immunological characterization of rLdTCP1γ for its prophylactic potential against visceral leishmaniasis in hamster model. Molecular Immunology 141, pages 33-42.
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Sandeep Verma, Deepak Kumar Deep, Poonam Gautam, Ruchi Singh & Poonam Salotra. (2021) Proteomic Analysis of Leishmania donovani Membrane Components Reveals the Role of Activated Protein C Kinase in Host-Parasite Interaction. Pathogens 10:9, pages 1194.
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Parvin Zamani, Seyedeh Hoda Alavizadeh, Fatemeh Fakhraee, Ali Badiee, Seyed Amir Jalali, Omid Chavoshian, Ali Khamesipour, Masoumeh Tavassoti Kheiri, Fereidoun Mahboudi & Mahmoud Reza Jaafari. (2021) Multi-antigen vaccination with LPD nanoparticles containing rgp63 and rLmaC1N proteins induced effective immune response against leishmaniasis in animal model. Journal of Drug Delivery Science and Technology 64, pages 102633.
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Samira Salari, Iraj Sharifi, Mehdi Bamorovat & Pooya Ghasemi Nejad Almani. (2021) The immunity of the recombinant prokaryotic and eukaryotic subunit vaccines against cutaneous leishmaniasis. Microbial Pathogenesis 153, pages 104807.
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Ozlem Ayse Tosyali, Adil Allahverdiyev, Melahat Bagirova, Emrah Sefik Abamor, Mehmet Aydogdu, Sahar Dinparvar, Tayfun Acar, Zeynep Mustafaeva & Serap Derman. (2021) Nano-co-delivery of lipophosphoglycan with soluble and autoclaved leishmania antigens into PLGA nanoparticles: Evaluation of in vitro and in vivo immunostimulatory effects against visceral leishmaniasis. Materials Science and Engineering: C 120, pages 111684.
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Roghiyeh Faridnia, Hamed Kalani, Hajar Ziaei Hezarjaribi, Paul W. Denny, Alireza Rafie, Mahdi Fakhar & Stela Virgilio. (2020) Apoptotic blebs from Leishmania major-infected macrophages as a new approach for cutaneous leishmaniasis vaccination. Microbial Pathogenesis 147, pages 104406.
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Aiman Saleh A. Mohammed, Weilu Tian, Youqin Zhang, Peng Peng, Fengshan Wang & Tianlu Li. (2020) Leishmania lipophosphoglycan components: A potent target for synthetic neoglycoproteins as a vaccine candidate for leishmaniasis. Carbohydrate Polymers 237, pages 116120.
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Mehmet Salih Gurel, Burak Tekin & Soner Uzun. (2020) Cutaneous leishmaniasis: A great imitator. Clinics in Dermatology 38:2, pages 140-151.
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Pragya Misra & Shailza Singh. 2020. Systems and Synthetic Immunology. Systems and Synthetic Immunology 1 52 .
Shahram Khademvatan, Kaveh Eskandari, Khosrow Hazrati-Tappeh, Fakher Rahim, Masoud Foroutan, Elham Yousefi & Negar Asadi. (2019) In silico and in vitro comparative activity of green tea components against Leishmania infantum. Journal of Global Antimicrobial Resistance 18, pages 187-194.
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Bhawana Singh, Sanjay Varikuti, Gregory Halsey, Greta Volpedo, Omar M Hamza & Abhay R Satoskar. (2019) Host-directed therapies for parasitic diseases. Future Medicinal Chemistry 11:15, pages 1999-2018.
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Lumena Louis, Megan Clark, Megan C. Wise, Nelson Glennie, Andrea Wong, Kate Broderick, Jude Uzonna, David B. Weiner & Phillip Scott. (2019) Intradermal Synthetic DNA Vaccination Generates Leishmania -Specific T Cells in the Skin and Protection against Leishmania major . Infection and Immunity 87:8.
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Farshid Yeganeh, Fereidoun Mahboudi, Nasser Gholijani, Farzaneh Barkhordari, Ghader Khalili & Eskandar Kamali-Sarvestani. (2019) Superoxide Dismutase B1, an Exacerbatory Antigen Elicits Interleukin-10 Production in Murine Leishmania major Infection. Archives of Clinical Infectious Diseases In Press:In Press.
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Pedro Cecílio, Fabiano Oliveira & Anabela Cordeiro da Silva. 2018. Leishmaniases as Re-emerging Diseases. Leishmaniases as Re-emerging Diseases.
Manas Ranjan Dikhit, Sushmita Das, Vijaya Mahantesh, Akhilesh Kumar, Ashish Kumar Singh, Budheswar Dehury, Ajaya Kumar Rout, Vahab Ali, Ganesh Chandra Sahoo, Roshan Kamal Topno, Krishna Pandey, V. N. R. Das, Sanjiva Bimal & Pradeep Das. (2018) The potential HLA Class I-restricted epitopes derived from LeIF and TSA of Leishmania donovani evoke anti-leishmania CD8+ T lymphocyte response. Scientific Reports 8:1.
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Daniel S. Dias, Vívian T. Martins, Patrícia A. F. Ribeiro, Fernanda F. Ramos, Daniela P. Lage, Grasiele S. V. Tavares, Débora V. C. Mendonça, Miguel A. Chávez-Fumagalli, Jamil S. Oliveira, Eduardo S. Silva, Dawidson A. Gomes, Michele A. Rodrigues, Mariana C. Duarte, Alexsandro S. Galdino, Daniel Menezes-Souza & Eduardo A. F. Coelho. (2017) Antigenicity, immunogenicity and protective efficacy of a conserved Leishmania hypothetical protein against visceral leishmaniasis . Parasitology 145:6, pages 740-751.
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Esther Garde, Laura Ramírez, Laura Corvo, José C. Solana, M. Elena Martín, Víctor M. González, Carlos Gómez-Nieto, Aldina Barral, Manoel Barral-Netto, José M. Requena, Salvador Iborra & Manuel Soto. (2018) Analysis of the Antigenic and Prophylactic Properties of the Leishmania Translation Initiation Factors eIF2 and eIF2B in Natural and Experimental Leishmaniasis. Frontiers in Cellular and Infection Microbiology 8.
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Sayonara M. Viana, Fabiana S. Celes, Laura Ramirez, Bala Kolli, Dennis K. P. Ng, Kwang P. Chang & Camila I. de Oliveira. (2018) Photodynamic Vaccination of BALB/c Mice for Prophylaxis of Cutaneous Leishmaniasis Caused by Leishmania amazonensis. Frontiers in Microbiology 9.
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Abdus Sabur, Sudipta Bhowmick, Rudra Chhajer, Sarfaraz Ahmad Ejazi, Nicky Didwania, Mohammad Asad, Anirban Bhattacharyya, Utsa Sinha & Nahid Ali. (2018) Liposomal Elongation Factor-1α Triggers Effector CD4 and CD8 T Cells for Induction of Long-Lasting Protective Immunity against Visceral Leishmaniasis. Frontiers in Immunology 9.
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Thaís Viana Fialho Martins, Ana Eliza Zeraik, Natália Oliveira Alves, Leandro Licursi de Oliveira, Tiago Antônio de Oliveira Mendes, Ricardo DeMarco & Eduardo de Almeida Marques-da-Silva. (2018) Lipophosphoglycan 3 From Leishmania infantum chagasi Binds Heparin With Micromolar Affinity . Bioinformatics and Biology Insights 12, pages 117793221876336.
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Partha Das, Dibyendu Paik, Ksudiram Naskar & Tapati Chakraborti. (2018) Leishmania donovani serine protease encapsulated in liposome elicits protective immunity in experimental visceral leishmaniasis. Microbes and Infection 20:1, pages 37-47.
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Eva Iniguez, Nathaniel S. Schocker, Krishanthi Subramaniam, Susana Portillo, Alba L. Montoya, Waleed S. Al-Salem, Caresse L. Torres, Felipe Rodriguez, Otacilio C. Moreira, Alvaro Acosta-Serrano, Katja Michael, Igor C. Almeida & Rosa A. Maldonado. (2017) An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major. PLOS Neglected Tropical Diseases 11:10, pages e0006039.
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Rafaianne Q. Moraes-Souza, Ana Paula Reinaque, Thaigra S. Soares, Ana Luiza T. Silva, Rodolfo C. Giunchetti, Maria A. S. Takano, Milena A. Akamatsu, Flávia S. Kubrusly, Fernanda Lúcio-Macarini, Isaias Raw, Dmitri Iourtov, Paulo Lee Ho, Lilian L. Bueno, Ricardo T. Fujiwara & Gustavo T. Volpato. (2017) Safety evaluation of a vaccine: Effect in maternal reproductive outcome and fetal anomaly frequency in rats using a leishmanial vaccine as a model. PLOS ONE 12:3, pages e0172525.
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Maria Agallou, Maritsa Margaroni, Evita Athanasiou, Dimitra K. Toubanaki, Katerina Kontonikola, Konstantina Karidi, Olga Kammona, Costas Kiparissides & Evdokia Karagouni. (2017) Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine. PLOS Neglected Tropical Diseases 11:1, pages e0005311.
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Hui Dong, Sihan Yang, Qiping Zhao, Hongyu Han, Shunhai Zhu, Xuelong Zhu, Cong Li, Ziwen Wang, Weili Xia, Qifei Men, Liangyu Yang & Bing Huang. (2016) Molecular characterization and protective efficacy of silent information regulator 2A from Eimeria tenella. Parasites & Vectors 9:1.
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Malcolm S. Duthie, Michelle Favila, Kimberley A. Hofmeyer, Yeung L. Tutterrow, Steven J. Reed, John D. Laurance, Alessandro Picone, Jeffrey Guderian, H. Remy Bailor, Aarthy C. Vallur, Hong Liang, Raodoh Mohamath, Julie Vergara, Randall F. Howard, Rhea N. Coler & Steven G. Reed. (2016) Strategic evaluation of vaccine candidate antigens for the prevention of Visceral Leishmaniasis. Vaccine 34:25, pages 2779-2786.
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Julie Healer & Alan F. Cowman. 2016. Molecular Parasitology. Molecular Parasitology 509 525 .
Henry J. C. de Vries, Sophia H. Reedijk & Henk D. F. H. Schallig. (2015) Cutaneous Leishmaniasis: Recent Developments in Diagnosis and Management. American Journal of Clinical Dermatology 16:2, pages 99-109.
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