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Expert Review of Vaccines Volume 13, 2014 - Issue 4
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Editorial

Targeting B-cell germlines and focusing affinity maturation: the next hurdles in HIV-1-vaccine development?

Max Medina-RamírezDepartment of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
,
Rogier W SandersDepartment of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY, USA
&
Per Johan KlasseDepartment of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY, USACorrespondence[email protected]
Pages 449-452 | Published online: 07 Mar 2014

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P. J. Klasse. (2016) How to assess the binding strength of antibodies elicited by vaccination against HIV and other viruses. Expert Review of Vaccines 15:3, pages 295-311.
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Articles from other publishers (16)

Flavio Matassoli, Alberto Cagigi, Chen-Hsiang Shen, Amy R. Henry, Timothy S. Johnston, Chaim A. Schramm, Christopher A. Cottrell, Oleksandr Kalyuzhniy, Abby Spangler, Leigh Eller, Merlin Robb, Michael Eller, Prossy Naluyima, Peter D. Kwong, Daniel C. Douek, William R. Schief, Sarah F. Andrews & Adrian B. McDermott. (2023) High frequency of HIV precursor-target-specific B cells in sub-Saharan populations. Cell Reports 42:12, pages 113450.
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Tommy Tong, Alessio D’Addabbo, Jiamin Xu, Himanshi Chawla, Albert Nguyen, Paola Ochoa, Max Crispin & James M. Binley. (2023) Impact of stabilizing mutations on the antigenic profile and glycosylation of membrane-expressed HIV-1 envelope glycoprotein. PLOS Pathogens 19:8, pages e1011452.
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Tom G. Caniels, Max Medina-Ramírez, Jinsong Zhang, Anita Sarkar, Sonu Kumar, Alex LaBranche, Ronald Derking, Joel D. Allen, Jonne L. Snitselaar, Joan Capella-Pujol, Iván del Moral Sánchez, Anila Yasmeen, Marilyn Diaz, Yoann Aldon, Tom P.L. Bijl, Sravani Venkatayogi, Joshua S. Martin Beem, Amanda Newman, Chuancang Jiang, Wen-Hsin Lee, Maarten Pater, Judith A. Burger, Mariëlle J. van Breemen, Steven W. de Taeye, Kimmo Rantalainen, Celia LaBranche, Kevin O. Saunders, David Montefiori, Gabriel Ozorowski, Andrew B. Ward, Max Crispin, John P. Moore, Per Johan Klasse, Barton F. Haynes, Ian A. Wilson, Kevin Wiehe, Laurent Verkoczy & Rogier W. Sanders. (2023) Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell Reports Medicine 4:4, pages 101003.
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Chunyan Yi, Caixia Su, Xiaoyu Sun, Xiao Lu, Chuanya Si, Caixuan Liu, Zhuo Yang, Hong Yuan, Yuying Huang, Jing Wen, Yonghui He, Yaguang Zhang, Liyan Ma, Yao Cong, Gan Zhao, Zhiyang Ling, Bin Wang & Bing Sun. (2023) A human antibody potently neutralizes RSV by targeting the conserved hydrophobic region of prefusion F. Science China Life Sciences 66:4, pages 729-742.
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Emma T. Crooks, Francisco Almanza, Alessio D’Addabbo, Erika Duggan, Jinsong Zhang, Kshitij Wagh, Huihui Mou, Joel D. Allen, Alyssa Thomas, Keiko Osawa, Bette T. Korber, Yaroslav Tsybovsky, Evan Cale, John Nolan, Max Crispin, Laurent K. Verkoczy & James M. Binley. (2021) Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens. PLOS Pathogens 17:10, pages e1009807.
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Chunyan Yi, Jing Xia, Lan He, Zhiyang Ling, Xuesong Wang, Yu Yan, Jiangjun Wang, Xinhao Zhao, Weiguo Fan, Xiaoyu Sun, Ronghua Zhang, Sheng Ye, Rongguang Zhang, Yongfen Xu, Liyan Ma, Yaguang Zhang, Honglin Zhou, Zhong Huang, Junqi Niu, Gang Long, Junxia Lu, Jin Zhong & Bing Sun. (2020) Junctional and somatic hypermutation-induced CX4C motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing antibody. Cellular & Molecular Immunology 18:3, pages 675-685.
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Ming Fu, Kai Hu, Huimin Hu, Fengfeng Ni, Tao Du, Robin J Shattock & Qinxue Hu. (2019) Antigenicity and immunogenicity of HIV-1 gp140 with different combinations of glycan mutation and V1/V2 region or V3 crown deletion. Vaccine 37:51, pages 7501-7508.
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Rajesh P. Ringe, Pavel Pugach, Christopher A. Cottrell, Celia C. LaBranche, Gemma E. Seabright, Thomas J. Ketas, Gabriel Ozorowski, Sonu Kumar, Anna Schorcht, Marit J. van Gils, Max Crispin, David C. Montefiori, Ian A. Wilson, Andrew B. Ward, Rogier W. Sanders, P. J. Klasse & John P. Moore. (2019) Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes. Journal of Virology 93:4.
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A. N. Vzorov & L. V. Uryvaev. (2017) Requirements for the Induction of Broadly Neutralizing Antibodies against HIV-1 by Vaccination. Molecular Biology 51:6, pages 819-829.
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Rogier W. Sanders & John P. Moore. (2017) Native-like Env trimers as a platform for HIV-1 vaccine design. Immunological Reviews 275:1, pages 161-182.
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Wei Cheng. (2016) The Density Code for the Development of a Vaccine?. Journal of Pharmaceutical Sciences 105:11, pages 3223-3232.
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P. J. Klasse, Celia C. LaBranche, Thomas J. Ketas, Gabriel Ozorowski, Albert Cupo, Pavel Pugach, Rajesh P. Ringe, Michael Golabek, Marit J. van Gils, Miklos Guttman, Kelly K. Lee, Ian A. Wilson, Salvatore T. Butera, Andrew B. Ward, David C. Montefiori, Rogier W. Sanders & John P. Moore. (2016) Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C. PLOS Pathogens 12:9, pages e1005864.
Crossref
Marina R. Alexander, Rajesh Ringe, Rogier W. Sanders, James E. Voss, John P. Moore & Per Johan Klasse. (2015) What Do Chaotrope-Based Avidity Assays for Antibodies to HIV-1 Envelope Glycoproteins Measure?. Journal of Virology 89:11, pages 5981-5995.
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Anila Yasmeen, Rajesh Ringe, Ronald Derking, Albert Cupo, Jean-Philippe Julien, Dennis R Burton, Andrew B Ward, Ian A Wilson, Rogier W Sanders, John P Moore & Per Johan Klasse. (2014) Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits. Retrovirology 11:1.
Crossref
Paul Goepfert & Anju Bansal. (2014) Human Immunodeficiency Virus Vaccines. Infectious Disease Clinics of North America 28:4, pages 615-631.
Crossref
Rogier W. Sanders & John P. Moore. (2014) A stamp on the envelope. Nature 514:7523, pages 437-438.
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