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Development of live attenuated influenza vaccines against pandemic influenza strains

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Asim Biswas, Alok K. Chakrabarti & Shanta Dutta. (2020) Current challenges: from the path of “original antigenic sin” towards the development of universal flu vaccines. International Reviews of Immunology 39:1, pages 21-36.
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Larisa Rudenko, Anatoly Naykhin, Svetlana Donina, Daniil Korenkov, Galina Petukhova, Irina Isakova-Sivak, Igor Losev, Marina Stukova, Mariana Erofeeva, Alexandra Nikiforova, Maureen Power & Jorge Flores. (2015) Assessment of immune responses to H5N1 inactivated influenza vaccine among individuals previously primed with H5N2 live attenuated influenza vaccine. Human Vaccines & Immunotherapeutics 11:12, pages 2839-2848.
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Irina Isakova-Sivak & Larisa Rudenko. (2015) Safety, immunogenicity and infectivity of new live attenuated influenza vaccines. Expert Review of Vaccines 14:10, pages 1313-1329.
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Jack A Panapasa, Rebecca J Cox, Kristin G I Mohn, Lara A Aqrawi & Karl A Brokstad. (2015) The expression of B & T cell activation markers in children's tonsils following live attenuated influenza vaccine. Human Vaccines & Immunotherapeutics 11:7, pages 1663-1672.
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Irina Isakova-Sivak, Marina Stukova, Mariana Erofeeva, Anatoly Naykhin, Svetlana Donina, Galina Petukhova, Victoria Kuznetsova, Irina Kiseleva, Tatiana Smolonogina, Irina Dubrovina, Maria Pisareva, Alexandra Nikiforova, Maureen Power, Jorge Flores & Larisa Rudenko. (2015) H2N2 live attenuated influenza vaccine is safe and immunogenic for healthy adult volunteers. Human Vaccines & Immunotherapeutics 11:4, pages 970-982.
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Larisa Rudenko & Irina Isakova-Sivak. (2015) Pandemic preparedness with live attenuated influenza vaccines based on A/Leningrad/134/17/57 master donor virus. Expert Review of Vaccines 14:3, pages 395-412.
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Piyush Dey, Akanksha Ahuja, Jaishal Panwar, Poonam Choudhary, Shital Rani, Mandeep Kaur, Akanksha Sharma, Jatinder Kaur, Ashok Kumar Yadav, Vikas Sood, Adukamparai R. Suresh Babu, Sanjay K. Bhadada, Gurpal Singh & Ravi Pratap Barnwal. (2023) Immune Control of Avian Influenza Virus Infection and Its Vaccine Development. Vaccines 11:3, pages 593.
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Richard Pebody & Kanta Subbarao. 2023. Plotkin's Vaccines. Plotkin's Vaccines 552 576.e8 .
Weigang Ren, Shuli Pei, Wenming Jiang, Meixia Zhao, Le Jiang, Honggang Liu, Yongxiang Yi, Mizhou Hui & Junwei Li. (2022) A replication-deficient H9N2 influenza virus carrying H5 hemagglutinin conferred protection against H9N2 and H5N1 influenza viruses in mice. Frontiers in Microbiology 13.
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Elien Vandoorn, Anna Parys, Sharon Chepkwony, Koen Chiers & Kristien Van Reeth. (2022) Efficacy of the NS1-truncated live attenuated influenza virus vaccine for swine against infection with viruses of major North American and European H3N2 lineages. Vaccine 40:19, pages 2723-2732.
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Ralph A. Tripp & John Stambas. (2021) Intervention Strategies for Seasonal and Emerging Respiratory Viruses with Drugs and Vaccines Targeting Viral Surface Glycoproteins. Viruses 13:4, pages 625.
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Darren Z. L. Mok & Kuan Rong Chan. (2020) The Effects of Pre-Existing Antibodies on Live-Attenuated Viral Vaccines. Viruses 12:5, pages 520.
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Kanta Subbarao. (2020) Live Attenuated Influenza Vaccines for Pandemic Preparedness. Journal of the Pediatric Infectious Diseases Society 9:Supplement_1, pages S15-S18.
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Raburn M. Mallory, Andrew Nyborg, Rubana N. Kalyani, Yuan Yuan, Stan L. Block & Filip Dubovsky. (2020) A study to evaluate the immunogenicity and shedding of live attenuated influenza vaccine strains in children 24–<48 months of age. Vaccine 38:5, pages 1001-1008.
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Angela Choi & Adolfo García-Sastre. 2020. Microbial Forensics. Microbial Forensics 89 104 .
Garima Singh, Manisha Pritam, Monisha Banerjee, Akhilesh Kumar Singh & Satarudra Prakash Singh. (2019) Genome based screening of epitope ensemble vaccine candidates against dreadful visceral leishmaniasis using immunoinformatics approach. Microbial Pathogenesis 136, pages 103704.
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Pui Wang, Min Zheng, Siu-Ying Lau, Pin Chen, Bobo Wing-Yee Mok, Siwen Liu, Honglian Liu, Xiaofeng Huang, Conor J. Cremin, Wenjun Song, Yixin Chen, Yik-Chun Wong, Haode Huang, Kelvin Kai-Wong To, Zhiwei Chen, Ningshao Xia, Kwok-Yung Yuen & Honglin Chen. (2019) Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines. mBio 10:5.
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Yao Sun, Zhenwei Shen, Chun Zhang, Yanming Yi, Kunying Zhu, Fei Xu & Wei Kong. (2019) Development of a Stable Liquid Formulation for Live Attenuated Influenza Vaccine. Journal of Pharmaceutical Sciences 108:7, pages 2315-2322.
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Feng Wen, Jinyue Guo & Shujian Huang. (2018) A meta‐analysis identified genes responsible for distinct immune responses to trivalent inactivated and live attenuated influenza vaccines. Journal of Cellular Physiology 234:4, pages 5196-5202.
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Daithi S. Heffernan. (2019) Influenza and the Surgeon. Surgical Infections 20:2, pages 119-128.
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Marios Koutsakos, Katherine Kedzierska & Kanta Subbarao. (2019) Immune Responses to Avian Influenza Viruses. The Journal of Immunology 202:2, pages 382-391.
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Clement Meseko, Binod Kumar & Melvin Sanicas. 2018. Influenza - Therapeutics and Challenges. Influenza - Therapeutics and Challenges.
Sinthujan Jegaskanda, Rosemarie D. Mason, Sarah F. Andrews, Adam K. Wheatley, Ruijun Zhang, Glennys V. Reynoso, David R. Ambrozak, Celia P. Santos, Catherine J. Luke, Yumiko Matsuoka, Jason M. Brenchley, Heather D. Hickman, Kawsar R. Talaat, Sallie R. Permar, Hua-Xin Liao, Jonathan W. Yewdell, Richard A. Koup, Mario Roederer, Adrian B. McDermott & Kanta Subbarao. (2018) Intranasal Live Influenza Vaccine Priming Elicits Localized B Cell Responses in Mediastinal Lymph Nodes. Journal of Virology 92:9.
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Catherine J. Luke, Seema S. Lakdawala & Kanta Subbarao. 2018. Plotkin's Vaccines. Plotkin's Vaccines 489 510.e7 .
Peggy Riese & Carlos A. Guzmán. (2017) Roads to advanced vaccines: influenza case study. Microbial Biotechnology 10:5, pages 1036-1040.
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Victoria Matyushenko, Irina Isakova-Sivak, Tatiana Smolonogina, Irina Dubrovina, Tatiana Tretiak & Larisa Rudenko. (2017) Genotyping assay for differentiation of wild-type and vaccine viruses in subjects immunized with live attenuated influenza vaccine. PLOS ONE 12:7, pages e0180497.
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Andrey Rekstin, Irina Isakova-Sivak, Galina Petukhova, Daniil Korenkov, Igor Losev, Tatiana Smolonogina, Tatiana Tretiak, Svetlana Donina, Svetlana Shcherbik, Tatiana Bousse & Larisa Rudenko. (2017) Immunogenicity and Cross Protection in Mice Afforded by Pandemic H1N1 Live Attenuated Influenza Vaccine Containing Wild-Type Nucleoprotein. BioMed Research International 2017, pages 1-11.
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Zhenwei Shen, Richard A. Bowen, Peng Ge, Jinfei Yu, Yanjie Shen, Wei Kong, Chunlai Jiang, Jinchang Wu, Changlin Zhu, Yanjun Xu, Wei Wei, Larisa Rudenko, Irina Kiseleva & Fei Xu. (2016) Evaluation of a candidate live attenuated influenza vaccine prepared in Changchun BCHT (China) for safety and efficacy in ferrets. Vaccine 34:48, pages 5953-5958.
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Elena Gianchecchi, Claudia Trombetta, Simona Piccirella & Emanuele Montomoli. (2016) Evaluating influenza vaccines: progress and perspectives. Future Virology 11:5, pages 379-393.
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Larisa Rudenko, Irina Isakova-Sivak, Anatoly Naykhin, Irina Kiseleva, Marina Stukova, Mariana Erofeeva, Daniil Korenkov, Victoria Matyushenko, Erin Sparrow & Marie-Paule Kieny. (2016) H7N9 live attenuated influenza vaccine in healthy adults: a randomised, double-blind, placebo-controlled, phase 1 trial. The Lancet Infectious Diseases 16:3, pages 303-310.
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Irina Kiseleva, Irina Dubrovina, Ekaterina Fedorova, Natalie Larionova, Irina Isakova–Sivak, Ekaterina Bazhenova, Maria Pisareva, Victoria Kuznetsova, Jorge Flores & Larisa Rudenko. (2015) Genetic stability of live attenuated vaccines against potentially pandemic influenza viruses. Vaccine 33:49, pages 7008-7014.
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Rita Czako & Kanta Subbarao. (2015) Refining the approach to vaccines against influenza A viruses with pandemic potential. Future Virology 10:9, pages 1033-1047.
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Huihui Kong, Qianyi Zhang, Chunyang Gu, Jianzhong Shi, Guohua Deng, Shujie Ma, Jinxiong Liu, Pucheng Chen, Yuntao Guan, Yongping Jiang & Hualan Chen. (2015) A live attenuated vaccine prevents replication and transmission of H7N9 virus in mammals. Scientific Reports 5:1.
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YanChun Peng, Beibei Wang, Kawsar Talaat, Ruth Karron, Timothy J. Powell, Hui Zeng, Danning Dong, Catherine J. Luke, Andrew McMichael, Kanta Subbarao & Tao Dong. (2015) Boosted Influenza-Specific T Cell Responses after H5N1 Pandemic Live Attenuated Influenza Virus Vaccination. Frontiers in Immunology 6.
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M. Trondsen, L. A. Aqrawi, F. Zhou, G. Pedersen, M. C. Trieu, P. Zhou & R. J. Cox. (2015) Induction of Local Secretory IgA and Multifunctional CD 4 + T‐helper Cells Following Intranasal Immunization with a H5N1 Whole Inactivated Influenza Virus Vaccine in BALB /c Mice . Scandinavian Journal of Immunology 81:5, pages 305-317.
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Claudia Trombetta, Simona Piccirella, Daniele Perini, Otfried Kistner & Emanuele Montomoli. (2015) Emerging Influenza Strains in the Last Two Decades: A Threat of a New Pandemic?. Vaccines 3:1, pages 172-185.
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Katherine Houser & Kanta Subbarao. (2015) Influenza Vaccines: Challenges and Solutions. Cell Host & Microbe 17:3, pages 295-300.
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Donald M. Carter, Chalise E. Bloom, Greg A. Kirchenbaum, Vadim Tsvetnitsky, Irina Isakova-Sivak, Larisa Rudenko & Ted M. Ross. (2015) Cross-protection against H7N9 influenza strains using a live-attenuated H7N3 virus vaccine. Vaccine 33:1, pages 108-116.
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