Advanced search
Publication Cover
Expert Review of Vaccines Volume 14, 2015 - Issue 5
Submit an article Journal homepage
209
Views
23
CrossRef citations to date
0
Altmetric
Review

Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease

Fernando J Sánchez-ValdézInstituto de Patología Experimental-CONICET, Universidad Nacional de Salta, Salta, ArgentinaCorrespondence[email protected]
,
Cecilia Pérez BrandánInstituto de Patología Experimental-CONICET, Universidad Nacional de Salta, Salta, Argentina
,
Arturo FerreiraPrograma Disciplinario de Inmunología, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
&
Miguel Ángel BasombríoInstituto de Patología Experimental-CONICET, Universidad Nacional de Salta, Salta, Argentina
Pages 681-697 | Published online: 11 Dec 2014

Citations (23)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Abel Ramos-Vega, Elizabeth Monreal-Escalante, Eric Dumonteil, Bernardo Bañuelos-Hernández & Carlos Angulo. (2021) Plant-made vaccines against parasites: bioinspired perspectives to fight against Chagas disease. Expert Review of Vaccines 20:11, pages 1373-1388.
Read now
Christian Quijia Quezada, Clênia S Azevedo, Sébastien Charneau, Jaime M Santana, Marlus Chorilli, Marcella B Carneiro & Izabela Marques Dourado Bastos. (2019) Advances in nanocarriers as drug delivery systems in Chagas disease. International Journal of Nanomedicine 14, pages 6407-6424.
Read now

Articles from other publishers (21)

Nisha Singh. 2023. Parasitic Infections. Parasitic Infections 356 381 .
Bijay Kumar Jha, Sanjay Varikuti, Chaitenya Verma, Rahul Shivahare, Nicholas Bishop, Gregory P. Dos Santos, Jacquelyn McDonald, Aakash Sur, Peter J. Myler, Sergio Schenkman, Abhay R. Satoskar & Bradford S. McGwire. (2023) Immunization with a Trypanosoma cruzi cyclophilin-19 deletion mutant protects against acute Chagas disease in mice. npj Vaccines 8:1.
Crossref
María Elisa Vázquez, Andrea Cecilia Mesías, Leonardo Acuña, Joseph Spangler, Brenda Zabala, Cecilia Parodi, Meghna Thakur, Eunkeu Oh, Scott Allan Walper & Cecilia Pérez Brandán. (2023) Exploring the performance of Escherichia coli outer membrane vesicles as a tool for vaccine development against Chagas disease. Memórias do Instituto Oswaldo Cruz 118.
Crossref
Debora B. Scariot, Austeja Staneviciute, Jennifer Zhu, Xiaomo Li, Evan A. Scott & David M. Engman. (2022) Leishmaniasis and Chagas disease: Is there hope in nanotechnology to fight neglected tropical diseases?. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Edio Maldonado, Sebastian Morales-Pison, Fabiola Urbina & Aldo Solari. (2022) Vaccine Design against Chagas Disease Focused on the Use of Nucleic Acids. Vaccines 10:4, pages 587.
Crossref
Rashika El Ridi. 2022. Encyclopedia of Infection and Immunity. Encyclopedia of Infection and Immunity 510 529 .
Isabel Marcelino, Adela Chavez, Mohamed Gharbi, Marisa Farber, Philippe Holzmuller, Dominique Martinez & Nathalie Vachiéry. 2021. Veterinary Vaccines. Veterinary Vaccines 77 99 .
Satabdi Datta Choudhury. (2021) Nano-Medicines a Hope for Chagas Disease!. Frontiers in Molecular Biosciences 8.
Crossref
Augusto E. Bivona, Andrés Sánchez Alberti, Natacha Cerny, Sebastián N. Trinitario & Emilio L. Malchiodi. (2020) Chagas disease vaccine design: the search for an efficient Trypanosoma cruzi immune-mediated control. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866:5, pages 165658.
Crossref
Andrés Sanchez Alberti, Augusto E. Bivona, Marina N. Matos, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Germán González, Celina Morales, Alejandro C. Cardoso, Silvia I. Cazorla, Carlos A. Guzmán & Emilio L. Malchiodi. (2020) Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi. Frontiers in Immunology 11.
Crossref
Lizette E. Rios, Juan Carlos Vázquez-Chagoyán, Antonio Ortega Pacheco, M. Paola Zago & Nisha J. Garg. (2019) Immunity and vaccine development efforts against Trypanosoma cruzi. Acta Tropica 200, pages 105168.
Crossref
Shivali Gupta, Berenice Salgado-Jiménez, Nandadeva Lokugamage, Juan Carlos Vázquez-Chagoyán & Nisha Jain Garg. (2019) TcG2/TcG4 DNA Vaccine Induces Th1 Immunity Against Acute Trypanosoma cruzi Infection: Adjuvant and Antigenic Effects of Heterologous T. rangeli Booster Immunization. Frontiers in Immunology 10.
Crossref
Eric Dumonteil, Claudia Herrera & Pierre Buekens. (2019) A therapeutic preconceptional vaccine against Chagas disease: A novel indication that could reduce congenital transmission and accelerate vaccine development. PLOS Neglected Tropical Diseases 13:1, pages e0006985.
Crossref
Cecilia Pérez Brandán, Andrea C Mesias, Leonardo Acuña, Thaise Lara Teixeira & Claudio Vieira da Silva. (2019) Evaluation of pathogen P21 protein as a potential modulator of the protective immunity induced by Trypanosoma cruzi attenuated parasites. Memórias do Instituto Oswaldo Cruz 114.
Crossref
Andrea González, Steffen Härtel, Jorge Mansilla, Fernando Sánchez-Valdéz & Arturo Ferreira. (2018) Variable numbers of calreticulin genes in Trypanosoma cruzi correlate with atypical morphology and protein expression. Immunobiology 223:12, pages 802-806.
Crossref
Judith I. Keller, Bryan A. Ballif, Riley M. St. Clair, James J. Vincent, M. Carlota Monroy & Lori Stevens. (2017) Chagas disease vector blood meal sources identified by protein mass spectrometry. PLOS ONE 12:12, pages e0189647.
Crossref
Cecilia Pérez Brandán, Andrea C. Mesías, Cecilia Parodi, Rubén O. Cimino, Carolina Pérez Brandán, Patricio Diosque & Miguel Ángel Basombrío. (2017) Effects of IFN-γ coding plasmid supplementation in the immune response and protection elicited by Trypanosoma cruzi attenuated parasites. BMC Infectious Diseases 17:1.
Crossref
A.M. Padilla, C.P. Brandan & M.A. Basombrío. 2017. American Trypanosomiasis Chagas Disease. American Trypanosomiasis Chagas Disease 773 796 .
Coreen M. Beaumier, Portia M. Gillespie, Ulrich Strych, Tara Hayward, Peter J. Hotez & Maria Elena Bottazzi. (2016) Status of vaccine research and development of vaccines for Chagas disease. Vaccine 34:26, pages 2996-3000.
Crossref
KARINA P. DE SOUSA & DENISE L. DOOLAN. (2016) Immunomics: a 21st century approach to vaccine development for complex pathogens. Parasitology 143:2, pages 236-244.
Crossref
Charlotte Mignon, Régis Sodoyer & Bettina Werle. (2015) Antibiotic-Free Selection in Biotherapeutics: Now and Forever. Pathogens 4:2, pages 157-181.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.