Advanced search
Publication Cover
Expert Review of Vaccines Volume 6, 2007 - Issue 3
Submit an article Journal homepage
204
Views
27
CrossRef citations to date
0
Altmetric
Review

Live-attenuated Salmonella as a prototype vaccine vector for passenger immunogens in humans: are we there yet?

George K Lewis Professor and Co-Director, Division of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute and University of Maryland Baltimore, 725 W. Lombard Street, Baltimore, MD 21218, USA. [email protected]
Pages 431-440 | Published online: 09 Jan 2014

Citations (27)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Norma Bloy, Aitziber Buqué, Fernando Aranda, Francesca Castoldi, Alexander Eggermont, Isabelle Cremer, Catherine Sautès-Fridman, Jitka Fucikova, Jérôme Galon, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2015) Trial watch: Naked and vectored DNA-based anticancer vaccines. OncoImmunology 4:5.
Read now
Amit A. Lugade, Suresh Kalathil, Jonathan L. Heald & Yasmin Thanavala. (2010) Transgenic Plant-Based Oral Vaccines. Immunological Investigations 39:4-5, pages 468-482.
Read now
Amit K Goyal, Kapil Khatri, Neeraj Mishra & Suresh P Vyas. (2008) New patents on mucosal delivery of vaccines. Expert Opinion on Therapeutic Patents 18:11, pages 1271-1288.
Read now
Lina Wang & Ross L Coppel. (2008) Oral vaccine delivery: can it protect against non-mucosal pathogens?. Expert Review of Vaccines 7:6, pages 729-738.
Read now

Articles from other publishers (23)

Chandran Sivasankar, Chamith Hewawaduge, Pandiyan Muthuramalingam & John Hwa Lee. (2023) Tumor-targeted delivery of lnc antisense RNA against RCAS1 by live-attenuated tryptophan-auxotrophic Salmonella inhibited 4T1 breast tumors and metastasis in mice. Molecular Therapy - Nucleic Acids 34, pages 102053.
Crossref
Asmat Ali, Abdul Waris, Muhammad Ajmal Khan, Muhammad Asim, Atta Ullah Khan, Sahrish Khan & Jehan Zeb. (2023) Recent advancement, immune responses, and mechanism of action of various vaccines against intracellular bacterial infections. Life Sciences 314, pages 121332.
Crossref
Dinesh Kumar Chellappan, Richie R. Bhandare, Afzal B. Shaik, Krishna Prasad, Nurfatihah Azlyna Ahmad Suhaimi, Wei Sheng Yap, Arpita Das, Pradipta Banerjee, Nandini Ghosh, Tanner Guith, Amitava Das, Sarannya Balakrishnan, Mayuren Candasamy, Jayashree Mayuren, Kishneth Palaniveloo, Gaurav Gupta, Sachin Kumar Singh & Kamal Dua. (2022) Vaccine for Diabetes—Where Do We Stand?. International Journal of Molecular Sciences 23:16, pages 9470.
Crossref
Marcela Pereira, Ju Kyoung Oh, Dae-Kyung Kang, Lars Engstrand & Valerie Diane Valeriano. (2022) Hacking Commensal Bacteria to Consolidate the Adaptive Mucosal Immune Response in the Gut–Lung Axis: Future Possibilities for SARS-CoV-2 Protection. BioTech 11:1, pages 3.
Crossref
Obaid S. Shaikh, Shari Rogal, Anam Malik, Vivek Sharma & Thomas Cacciarelli. (2020) Liver Transplant From Increased-Risk Donors in the Era of Direct-Acting Antivirals for Hepatitis C. Experimental and Clinical Transplantation 18:5, pages 605-611.
Crossref
Puyuan Tian, Yuqing Wang, Hui Liu, Yulu Yang, Xiaoli Wu, Hua Wei & Tingtao Chen. (2019) Preparation and Evaluation of the Fully Humanized Monoclonal Antibody GD-mAb Against Respiratory Syncytial Virus. Frontiers in Cellular and Infection Microbiology 9.
Crossref
Josephine E. Clark-Curtiss & Roy CurtissIIIIII. (2018) Salmonella Vaccines: Conduits for Protective Antigens . The Journal of Immunology 200:1, pages 39-48.
Crossref
Ivan Lin, Thi Van & Peter Smooker. (2015) Live-Attenuated Bacterial Vectors: Tools for Vaccine and Therapeutic Agent Delivery. Vaccines 3:4, pages 940-972.
Crossref
Zhenying Ji, Jing Shang, Yuan Li, Shifeng Wang & Huoying Shi. (2015) Live attenuated Salmonella enterica serovar Choleraesuis vaccine vector displaying regulated delayed attenuation and regulated delayed antigen synthesis to confer protection against Streptococcus suis in mice. Vaccine 33:38, pages 4858-4867.
Crossref
Milan Raska & Jaroslav Turanek. 2015. Mucosal Immunology. Mucosal Immunology 1307 1335 .
Awad Ali Shehata, Hesham Sultan, Hafez M. Hafez & Monika Krüger. (2013) Safety and Efficacy of a Metabolic Drift Live Attenuated Salmonella Gallinarum Vaccine Against Fowl Typhoid. Avian Diseases 57:1, pages 29-35.
Crossref
Frank Breinig, Tanja Breinig & Manfred J. Schmitt. 2013. Synthetic Messenger RNA and Cell Metabolism Modulation. Synthetic Messenger RNA and Cell Metabolism Modulation 163 184 .
B Walch, T Breinig, M J Schmitt & F Breinig. (2011) Delivery of functional DNA and messenger RNA to mammalian phagocytic cells by recombinant yeast. Gene Therapy 19:3, pages 237-245.
Crossref
Xiangmin Zhang, Soo-Young Wanda, Karen Brenneman, Wei Kong, Xin Zhang, Kenneth Roland & Roy CurtissIIIIII. (2011) Improving Salmonella vector with recmutation to stabilize the DNA cargoes. BMC Microbiology 11:1.
Crossref
Barbara Walch, Tanja Breinig, Gernot Geginat, Manfred J. Schmitt & Frank Breinig. (2011) Yeast-based protein delivery to mammalian phagocytic cells is increased by coexpression of bacterial listeriolysin. Microbes and Infection 13:11, pages 908-913.
Crossref
Qingke Kong, David A. Six, Kenneth L. Roland, Qing Liu, Lillian Gu, C. Michael Reynolds, Xiaoyuan Wang, Christian R. H. Raetz & Roy CurtissIIIIII. (2011) Salmonella Synthesizing 1-Monophosphorylated Lipopolysaccharide Exhibits Low Endotoxic Activity while Retaining Its Immunogenicity . The Journal of Immunology 187:1, pages 412-423.
Crossref
Shifeng Wang, Yuhua Li, Huoying Shi, Wei Sun, Kenneth L. Roland & Roy CurtissIIIIII. (2011) Comparison of a Regulated Delayed Antigen Synthesis System with In Vivo -Inducible Promoters for Antigen Delivery by Live Attenuated Salmonella Vaccines . Infection and Immunity 79:2, pages 937-949.
Crossref
Ana Blanco-Toribio, Serge Muyldermans, Gad Frankel & Luis Ángel Fernández. (2010) Direct Injection of Functional Single-Domain Antibodies from E. coli into Human Cells. PLoS ONE 5:12, pages e15227.
Crossref
Xian Tang & Zhiwei Chen. (2010) The Development of an AIDS Mucosal Vaccine. Viruses 2:1, pages 283-297.
Crossref
Dirk Bumann. (2009) System-level analysis of Salmonella metabolism during infection. Current Opinion in Microbiology 12:5, pages 559-567.
Crossref
Xiangmin Zhang, Wei Kong, Shamaila Ashraf & Roy CurtissIIIIII. (2009) A One-Plasmid System To Generate Influenza Virus in Cultured Chicken Cells for Potential Use in Influenza Vaccine. Journal of Virology 83:18, pages 9296-9303.
Crossref
Manuel Osorio, Yanping Wu, Sunil Singh, Tod J. Merkel, Siba Bhattacharyya, Milan S. Blake & Dennis J. Kopecko. (2009) Anthrax Protective Antigen Delivered by Salmonella enterica Serovar Typhi Ty21a Protects Mice from a Lethal Anthrax Spore Challenge . Infection and Immunity 77:4, pages 1475-1482.
Crossref
Karina Ramirez, Alejandra V. E. Capozzo, Scott A. Lloyd, Marcelo B. Sztein, James P. Nataro & Marcela F. Pasetti. (2009) Mucosally Delivered Salmonella Typhi Expressing the Yersinia pestis F1 Antigen Elicits Mucosal and Systemic Immunity Early in Life and Primes the Neonatal Immune System for a Vigorous Anamnestic Response to Parenteral F1 Boost . The Journal of Immunology 182:2, pages 1211-1222.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.