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Review

Baculovirus as an expression and/or delivery vehicle for vaccine antigens

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Pages 363-371 | Published online: 09 Jan 2014

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Laurent Durous, Manuel Rosa-Calatrava & Emma Petiot. (2019) Advances in influenza virus-like particles bioprocesses. Expert Review of Vaccines 18:12, pages 1285-1300.
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Shih-Yeh Lin, Yao-Chi Chung & Yu-Chen Hu. (2014) Update on baculovirus as an expression and/or delivery vehicle for vaccine antigens. Expert Review of Vaccines 13:12, pages 1501-1521.
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Tzong-Yuan Wu, Ying-Ju Chen, Chao-Yi Teng, Wen-Shuo Chen & Oliver Villaflores. (2012) A bi-cistronic baculovirus expression vector for improved recombinant protein production. Bioengineered 3:2, pages 129-132.
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Jimmy A Mena & Amine A Kamen. (2011) Insect cell technology is a versatile and robust vaccine manufacturing platform. Expert Review of Vaccines 10:7, pages 1063-1081.
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Blaise Genton. (2008) Malaria vaccines: a toy for travelers or a tool for eradication?. Expert Review of Vaccines 7:5, pages 597-611.
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Articles from other publishers (58)

Aaron Pavel Rodríguez-Hernández, Daniel Martínez-Flores, Adolfo Cruz-Reséndiz, Teresa Padilla-Flores, Rodrigo González-Flores, Kenia Estrada, Alicia Sampieri, Aldo Román Camacho-Zarco & Luis Vaca. (2023) Baculovirus Display of Peptides and Proteins for Medical Applications. Viruses 15:2, pages 411.
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Matías L. Pidre, Paula N. Arrías, Leslie C. Amorós Morales & Víctor Romanowski. (2022) The Magic Staff: A Comprehensive Overview of Baculovirus-Based Technologies Applied to Human and Animal Health. Viruses 15:1, pages 80.
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Adolfo Cruz-Resendiz, Gonzalo Acero, Alicia Sampieri, Goar Gevorkian, Carolina Salvador, Laura Escobar, Margarita Jacaranda Rosendo-Pineda, Mara Medeiros & Luis Vaca. (2022) An ambient-temperature stable nanoparticle-based vaccine for nasal application that confers long-lasting immunogenicity to carried antigens. Frontiers in Immunology 13.
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Megha K. Bedekar, Sajal Kole & Makesh M.. 2022. Fish immune system and vaccines. Fish immune system and vaccines 45 63 .
Friederike Eilts, Julie Harnischfeger, Daniel Loewe, Michael W. Wolff, Denise Salzig & Peter Czermak. 2021. Vaccine Delivery Technology. Vaccine Delivery Technology 367 390 .
Mario Fragoso‐Saavedra & Marco A. Vega‐López. (2020) Induction of mucosal immunity against pathogens by using recombinant baculoviral vectors: Mechanisms, advantages, and limitations. Journal of Leukocyte Biology 108:3, pages 835-850.
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Megha Kadam Bedekar, Sajal Kole & Gayatri Tripathi. 2020. Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries. Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries 407 419 .
Kun Li, Rui Yuan, Mingtian Zhang, Tingting Zhang, Yuchao Gu, Yang Zhou, Yaping Dai, Ping Fang, Yongjie Feng, Xiaolong Hu, Guangli Cao, Renyu Xue, Hui Chen & Chengliang Gong. (2019) Recombinant baculovirus BacCarassius-D4ORFs has potential as a live vector vaccine against CyHV-2. Fish & Shellfish Immunology 92, pages 101-110.
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Tingting Li, Zhenyong Zhang, Zhiqing Zhang, Jiaming Qiao, Rui Rong, Yuyun Zhang, Qiaobin Yao, Zekai Li, Honglin Shen, Fang Huang, Wenhui Xue, Shuangquan Gao, Shaoyong Li, Qingbing Zheng, Hai Yu, Jun Zhang, Ying Gu, Shaowei Li & Ningshao Xia. (2019) Characterization of native-like HIV-1 gp140 glycoprotein expressed in insect cells. Vaccine 37:11, pages 1418-1427.
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Chia-Wei Lin, Ming-Chu Cheng, Shih-Yeh Lin, Shi-Hsiao Hung, Shun-Yu Jhang, Chin-Wei Chang, Poa-Chun Chang & Yu-Chen Hu. (2018) Hybrid baculovirus-mediated prolonged hemagglutinin expression and secretion in vivo enhances the vaccine efficacy. Journal of the Taiwan Institute of Chemical Engineers 91, pages 47-56.
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Ming Kong, Huan Zuo, Feifei Zhu, Zhaoyang Hu, Liang Chen, Yanhua Yang, Peng Lv, Qin Yao & Keping Chen. (2018) The interaction between baculoviruses and their insect hosts. Developmental & Comparative Immunology 83, pages 114-123.
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Jida Xing, Shrishti Singh, Yupeng Zhao, Yan Duan, Huining Guo, Chenxia Hu, Allan Ma, Rajan George, James Z. Xing, Ankarao Kalluri, Isaac Macwan, Prabir Patra & Jie Chen. (2017) Increasing vaccine production using pulsed ultrasound waves. PLOS ONE 12:11, pages e0187048.
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Chia-Hung Wang, Nenavath Gopal Naik, Lin-Li Liao, Sung-Chan Wei & Yu-Chan Chao. (2017) Global Screening of Antiviral Genes that Suppress Baculovirus Transgene Expression in Mammalian Cells. Molecular Therapy - Methods & Clinical Development 6, pages 194-206.
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Zhuangli Bi, Yingqi Zhu, Zongyan Chen, Chuanfeng Li, Yong Wang, Guijun Wang & Guangqing Liu. (2016) Induction of a robust immunity response against novel duck reovirus in ducklings using a subunit vaccine of sigma C protein. Scientific Reports 6:1.
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Bo Liu, Yongchang Gong, Zhen Li, Xiaolong Hu, Guangli Cao, Renyu Xue & Chengliang Gong. (2016) Baculovirus-mediated GCRV vp7 and vp6 genes expression in silkworm and grass carp. Molecular Biology Reports 43:6, pages 509-515.
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Hongli Jin, Xiaohong Xia, Bing Liu, Yu Fu, Xianping Chen, Huihui Wang & Zhenqiang Xia. (2015) High-yield production of canine parvovirus virus-like particles in a baculovirus expression system. Archives of Virology 161:3, pages 705-710.
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Timothy Weixin Kwang, Xinhui Zeng & Shu Wang. (2016) Manufacturing of AcMNPV baculovirus vectors to enable gene therapy trials. Molecular Therapy - Methods & Clinical Development 3, pages 15050.
Crossref
Anthony O. Ejiofor. 2016. Short Views on Insect Genomics and Proteomics. Short Views on Insect Genomics and Proteomics 185 210 .
M. Pérez-Hernández, I. Gadea, J.M. Escribano, E. Tabarés & S. Gómez-Sebastián. (2015) Expression and characterization of the gD protein of HSV-2 fused to the tetramerization domain of the transcription factor p53. Protein Expression and Purification 115, pages 54-60.
Crossref
Shih-Yeh Lin, Chia-Tsui Yeh, Wan-Hua Li, Cheng-Ping Yu, Wen-Chin Lin, Jyh-Yuan Yang, Hsueh-Ling Wu & Yu-Chen Hu. (2015) Enhanced enterovirus 71 virus-like particle yield from a new baculovirus design. Biotechnology and Bioengineering 112:10, pages 2005-2015.
Crossref
Jida Xing, Chenxia Hu, Allan Ma, Rajan George, James Z. Xing & Jie Chen. (2015) Pulsed ultrasound for enhancing vaccine production. Pulsed ultrasound for enhancing vaccine production.
Kaisa-Emilia Makkonen, Kari Airenne & Seppo Ylä-Herttulala. (2015) Baculovirus-mediated Gene Delivery and RNAi Applications. Viruses 7:4, pages 2099-2125.
Crossref
Emily P. Wen, Ronald Ellis & Narahari S. PujarNarahari S. Pujar, Sangeetha L. Sagar & Ann L. Lee. 2014. Vaccine Development and Manufacturing. Vaccine Development and Manufacturing 1 24 .
Li-Yu Sung, Chiu-Ling Chen, Shih-Yeh Lin, Kuei-Chang Li, Chia-Lin Yeh, Guan-Yu Chen, Chin-Yu Lin & Yu-Chen Hu. (2014) Efficient gene delivery into cell lines and stem cells using baculovirus. Nature Protocols 9:8, pages 1882-1899.
Crossref
Yu-Chen HuYu-Chen Hu. 2014. Gene Therapy for Cartilage and Bone Tissue Engineering. Gene Therapy for Cartilage and Bone Tissue Engineering 17 31 .
Kari J Airenne, Yu-Chen Hu, Thomas A Kost, Richard H Smith, Robert M Kotin, Chikako Ono, Yoshiharu Matsuura, Shu Wang & Seppo Ylä-Herttuala. (2013) Baculovirus: an Insect-derived Vector for Diverse Gene Transfer Applications. Molecular Therapy 21:4, pages 739-749.
Crossref
Oliver B. Villaflores, Chein-Ming Hsei, Chao-Yi Teng, Ying-Ju Chen, Jiunn-Jye Wey, Pei-Yi Tsui, Rong-Hwa Shyu, Kuo-Lun Tung, Jui-Ming Yeh, Der-Jiang Chiao & Tzong-Yuan Wu. (2013) Easy expression of the C-terminal heavy chain domain of botulinum neurotoxin serotype A as a vaccine candidate using a bi-cistronic baculovirus system. Journal of Virological Methods 189:1, pages 58-64.
Crossref
Chi-Yuan Chen, Shih-Yeh Lin, Ming-Chu Cheng, Ching-Ping Tsai, Chang-Lin Hung, Kai-Wei Lo, Yung Hwang & Yu-Chen Hu. (2013) Baculovirus vector as an avian influenza vaccine: Hemagglutinin expression and presentation augment the vaccine immunogenicity. Journal of Biotechnology 164:1, pages 143-150.
Crossref
Xiaodong Xu, Yuanrong Chen, Yu Zhao, Xiaofen Liu, Beitao Dong, Ian M. Jones & Hongying Chen. (2013) Baculovirus Superinfection: A Probable Restriction Factor on the Surface Display of Proteins for Library Screening. PLoS ONE 8:1, pages e54631.
Crossref
Renyu Xue, Lin Liu, Guangli Cao, Shiying Xu, Jinghui Li, Yong Zou, Hui Chen & Chengliang Gong. (2013) Oral vaccination of BacFish-vp6 against grass carp reovirus evoking antibody response in grass carp. Fish & Shellfish Immunology 34:1, pages 348-355.
Crossref
Silvia Gómez-Sebastián, Maria C Nuñez, Lorena Garaicoechea, Carmen Alvarado, Marina Mozgovoj, Rodrigo Lasa, Alan Kahl, Andres Wigdorovitz, Viviana Parreño & José M Escribano. (2012) Rotavirus A-specific single-domain antibodies produced in baculovirus-infected insect larvae are protective in vivo. BMC Biotechnology 12:1.
Crossref
Chin-Yu Lin, Kun-Ju Lin, Kuei-Chang Li, Li-Yu Sung, Swei Hsueh, Chia-Hsin Lu, Guan-Yu Chen, Chiu-Ling Chen, Shiu-Feng Huang, Tzu-Chen Yen, Yu-Han Chang & Yu-Chen Hu. (2012) Immune responses during healing of massive segmental femoral bone defects mediated by hybrid baculovirus-engineered ASCs. Biomaterials 33:30, pages 7422-7434.
Crossref
Silvia Loureiro, Elena Robinson, Hongying Chen, Pongsathon Phapugrangkul, Camilo Colaco & Ian M Jones. 2012. Innovation in Vaccinology. Innovation in Vaccinology 45 63 .
Tommi Heikura, Tiina Nieminen, Miia M. Roschier, Henna Karvinen, Minna U. Kaikkonen, Anssi J. Mähönen, Hanna P. Lesch, Tuomas T. Rissanen, Olli H. Laitinen, Kari J. Airenne & Seppo Ylä-Herttuala. (2012) Baculovirus-mediated vascular endothelial growth factor-DΔNΔC gene transfer induces angiogenesis in rabbit skeletal muscle. The Journal of Gene Medicine 14:1, pages 35-43.
Crossref
Chiu-Ling Chen, Wen-Yi Luo, Wen-Hsin Lo, Kun-Ju Lin, Li-Yu Sung, Yung-Shen Shih, Yu-Han Chang & Yu-Chen Hu. (2011) Development of hybrid baculovirus vectors for artificial MicroRNA delivery and prolonged gene suppression. Biotechnology and Bioengineering 108:12, pages 2958-2967.
Crossref
Chi-Yuan Chen, Chin-Yu Lin, Guan-Yu Chen & Yu-Chen Hu. (2011) Baculovirus as a gene delivery vector: Recent understandings of molecular alterations in transduced cells and latest applications. Biotechnology Advances 29:6, pages 618-631.
Crossref
Chi-Yuan Chen, Hsiao-Hsuan Wu, Chih-Ping Chen, Schu-Rern Chern, Shiaw-Min Hwang, Shiu-Feng Huang, Wen-Hsin Lo, Guan-Yu Chen & Yu-Chen Hu. (2011) Biosafety Assessment of Human Mesenchymal Stem Cells Engineered by Hybrid Baculovirus Vectors. Molecular Pharmaceutics 8:5, pages 1505-1514.
Crossref
W-Y Luo, Y-S Shih, W-H Lo, H-R Chen, S-C Wang, C-H Wang, C-H Chien, C-S Chiang, Y-J Chuang & Y-C Hu. (2011) Baculovirus vectors for antiangiogenesis-based cancer gene therapy. Cancer Gene Therapy 18:9, pages 637-645.
Crossref
Chin-Yu Lin, Kun-Ju Lin, Chun-Yu Kao, Mu-Cheng Chen, Wen-Hsin Lo, Tzu-Chen Yen, Yu-Han Chang & Yu-Chen Hu. (2011) The role of adipose-derived stem cells engineered with the persistently expressing hybrid baculovirus in the healing of massive bone defects. Biomaterials 32:27, pages 6505-6514.
Crossref
Carlo Zambonelli, Deeann Martinez-Guzmann & Indresh K. Srivastava. 2011. Development of Vaccines. Development of Vaccines 185 213 .
António Roldão, Tiago Vicente, Cristina Peixoto, Manuel J.T. Carrondo & Paula M. Alves. (2011) Quality control and analytical methods for baculovirus-based products. Journal of Invertebrate Pathology 107, pages S94-S105.
Crossref
Minna U. Kaikkonen, Seppo Yl?-Herttuala & Kari J. Airenne. (2011) How to avoid complement attack in baculovirus-mediated gene delivery. Journal of Invertebrate Pathology 107, pages S71-S79.
Crossref
A. P. Solomko, O. A. Zaharuk, L. I. Chaschina & L. I. Strokovskaya. (2011) Baculovirus vectors in experimental gene- and vaccine therapy. Biopolymers and Cell 27:3, pages 167-180.
Crossref
Fengtao Huang, Shengbo Cao, Xiaoxian Cui, Chuanxi Xiong, Min Wang, Yuanan Lu, Weimin Wang, Jing Ye & Xueqin Liu. (2011) Efficient gene delivery into fish cells by an improved recombinant baculovirus. Journal of Virological Methods 173:2, pages 294-299.
Crossref
Tamer Z. Salem, Fengrui Zhang, Yan Xie & Suzanne M. Thiem. (2011) Comprehensive analysis of host gene expression in Autographa californica nucleopolyhedrovirus-infected Spodoptera frugiperda cells. Virology 412:1, pages 167-178.
Crossref
Kari J. Airenne, Kaisa-Emilia Makkonen, Anssi J. Mähönen & Seppo Ylä-Herttuala. 2011. Viral Vectors for Gene Therapy. Viral Vectors for Gene Therapy 279 301 .
Monique M van Oers & Dwight E Lynn. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences.
Chi-Yuan Chen, Hung-Jen Liu, Ching-Ping Tsai, Cheng-Yu Chung, Yung-Shen Shih, Poa-Chun Chang, Yung-Tsung Chiu & Yu-Chen Hu. (2010) Baculovirus as an avian influenza vaccine vector: Differential immune responses elicited by different vector forms. Vaccine 28:48, pages 7644-7651.
Crossref
Alicia Fernández-San Millán, Silvia Gómez-Sebastián, María C. Nuñez, Jon Veramendi & José M. Escribano. (2010) Human papillomavirus-like particles vaccine efficiently produced in a non-fermentative system based on insect larva. Protein Expression and Purification 74:1, pages 1-8.
Crossref
Eva Pérez-Martín, Silvia Gómez-Sebastián, Jordi M. Argilaguet, Marina Sibila, María Fort, Miquel Nofrarías, Sherry Kurtz, José M. Escribano, Joaquim Segalés & Fernando Rodríguez. (2010) Immunity conferred by an experimental vaccine based on the recombinant PCV2 Cap protein expressed in Trichoplusia ni-larvae. Vaccine 28:11, pages 2340-2349.
Crossref
Ching-Kuang ChuangKun-Ju LinChin-Yu LinYu-Han ChangTzu-Chen YenShiaw-Min HwangLi-Yu SungHuang-Chi ChenYu-Chen Hu. (2010) Xenotransplantation of Human Mesenchymal Stem Cells into Immunocompetent Rats for Calvarial Bone Repair. Tissue Engineering Part A 16:2, pages 479-488.
Crossref
Yves Durocher & Michael Butler. (2009) Expression systems for therapeutic glycoprotein production. Current Opinion in Biotechnology 20:6, pages 700-707.
Crossref
Yi Yang, Seong-Loong Lo, Jingye Yang, Jing Yang, Sally S.L. Goh, Chunxiao Wu, Si-Shen Feng & Shu Wang. (2009) Polyethylenimine coating to produce serum-resistant baculoviral vectors for in vivo gene delivery. Biomaterials 30:29, pages 5767-5774.
Crossref
Günther M. Keil, Constanze Klopfleisch, Katrin Giesow & Ulrike Blohm. (2009) Novel vectors for simultaneous high-level dual protein expression in vertebrate and insect cells by recombinant baculoviruses. Journal of Virological Methods 160:1-2, pages 132-137.
Crossref
T Vicente, C Peixoto, M J T Carrondo & P M Alves. (2009) Purification of recombinant baculoviruses for gene therapy using membrane processes. Gene Therapy 16:6, pages 766-775.
Crossref
Agnieszka K. Grabowska, Andrea D. Lipińska, Jörg Rohde, Boguslaw Szewczyk, Krystyna Bienkowska-Szewczyk & Hanns-Joachim Rziha. (2009) New baculovirus recombinants expressing Pseudorabies virus (PRV) glycoproteins protect mice against lethal challenge infection. Vaccine 27:27, pages 3584-3591.
Crossref
Ranjana Arya, Alok Bhattacharya & Kulvinder Singh Saini. (2008) Dictyostelium discoideum —a promising expression system for the production of eukaryotic proteins . The FASEB Journal 22:12, pages 4055-4066.
Crossref
Heng-Chun Shen, Chia-Ni Yeh, Guan-Yu Chen, Shiu-Feng Huang, Chi-Yuan Chen, Yung-Chung Chiu & Yu-Chen Hu. (2008) Sustained baculovirus-mediated expression in myogenic cells. The Journal of Gene Medicine 10:11, pages 1190-1197.
Crossref

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