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Review

Malaria vaccines: a toy for travelers or a tool for eradication?

Pages 597-611 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Thangavelu U Arumugam, Daisuke Ito, Eizo Takashima, Mayumi Tachibana, Tomoko Ishino, Motomi Torii & Takafumi Tsuboi. (2014) Application of wheat germ cell-free protein expression system for novel malaria vaccine candidate discovery. Expert Review of Vaccines 13:1, pages 75-85.
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Lin H Chen, David R Hill & Annelies Wilder-Smith. (2011) Vaccination of travelers: how far have we come and where are we going?. Expert Review of Vaccines 10:11, pages 1609-1620.
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Clarence M. Ongkudon, Jenny Ho & Michael K. Danquah. (2011) Mitigating the looming vaccine crisis: production and delivery of plasmid-based vaccines. Critical Reviews in Biotechnology 31:1, pages 32-52.
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Satoru Takeo, Thangavelu U Arumugam, Motomi Torii & Takafumi Tsuboi. (2009) Wheat germ cell-free technology for accelerating the malaria vaccine research. Expert Opinion on Drug Discovery 4:11, pages 1191-1199.
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Articles from other publishers (24)

Takeshi Miyata, Kosuke Minamihata, Koichi Kurihara, Yui Kamizuru, Mari Gotanda, Momoka Obayashi, Taiki Kitagawa, Keita Sato, Momoko Kimura, Kosuke Oyama, Yuta Ikeda, Yukihiro Tamaki, Jae Man Lee, Kozue Sakao, Daisuke Hamanaka, Takahiro Kusakabe, Mayumi Tachibana & Hisham R. Ibrahim. (2022) Highly efficient protein expression of Plasmodium vivax surface antigen, Pvs25, by silkworm and its biochemical analysis. Protein Expression and Purification 195-196, pages 106096.
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Srinivasa Reddy Bonam, Laurent Rénia, Ganesh Tadepalli, Jagadeesh Bayry & Halmuthur Mahabalarao Sampath Kumar. (2021) Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants. Vaccines 9:10, pages 1072.
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Sylvester Dassah, Bright Adu, Sodiomon B. Sirima, Benjamin Mordmüller, Ulysse Ateba Ngoa, Frank Atuguba, Fareed K.N. Arthur, Benedicta A. Mensah, Mark Kaddumukasa, Peter Bang, Peter G. Kremsner, Donnie Mategula, Clare Flach, Paul Milligan & Michael Theisen. (2021) Extended follow-up of children in a phase2b trial of the GMZ2 malaria vaccine. Vaccine 39:31, pages 4314-4319.
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Wenqi Zheng, Fei Liu, Feng Du, Fan Yang, Xu Kou, Yiwen He, Hui Feng, Qi Fan, Enjie Luo, Hui Min, Jun Miao, Liwang Cui & Yaming Cao. (2020) Characterization of a Sulfhydryl Oxidase From Plasmodium berghei as a Target for Blocking Parasite Transmission. Frontiers in Cellular and Infection Microbiology 10.
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Jorge Enrique Gómez Marín & Kamal El Bissati. (2019) Editorial: Innovative Therapeutic and Immunomodulatory Strategies for Protozoan Infections. Frontiers in Cellular and Infection Microbiology 9.
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Fauzi Muh, Jin-Hee Han, Myat Htut Nyunt, Seong-Kyun Lee, Hye-Yoon Jeon, Kwon-Soo Ha, Won Sun Park, Seok-Ho Hong, Md Atique Ahmed, Sunghun Na, Eizo Takashima, Takafumi Tsuboi & Eun-Taek Han. (2017) Identification of a novel merozoite surface antigen of Plasmodium vivax, PvMSA180. Malaria Journal 16:1.
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Valerian L. Kiggundu, Wendy P. O'Meara, Richard Musoke, Fred K. Nalugoda, Godfrey Kigozi, Enos Baghendaghe, Tom Lutalo, Marion K. Achienge, Steven J. Reynolds, Fred Makumbi, David Serwadda, Ronald H. Gray & Kara K. Wools-Kaloustian. (2013) High Prevalence of Malaria Parasitemia and Anemia among Hospitalized Children in Rakai, Uganda. PLoS ONE 8:12, pages e82455.
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Niwat Kangwanrangsan, Mayumi Tachibana, Rachaneeporn Jenwithisuk, Takafumi Tsuboi, Suda Riengrojpitak, Motomi Torii & Tomoko Ishino. (2013) A member of the CPW-WPC protein family is expressed in and localized to the surface of developing ookinetes. Malaria Journal 12:1.
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Tatjana Feller, Pascal Thom, Natalie Koch, Holger Spiegel, Otchere Addai-Mensah, Rainer Fischer, Andreas Reimann, Gabriele Pradel, Rolf Fendel, Stefan Schillberg, Matthias Scheuermayer & Helga Schinkel. (2013) Plant-Based Production of Recombinant Plasmodium Surface Protein Pf38 and Evaluation of its Potential as a Vaccine Candidate. PLoS ONE 8:11, pages e79920.
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Ann M. Moormann, Peter Odada Sumba, Kiprotich Chelimo, Hua Fang, Daniel J. Tisch, Arlene E. Dent, Chandy C. John, Carole A. Long, John Vulule & James W. Kazura. (2013) Humoral and Cellular Immunity to Plasmodium falciparum Merozoite Surface Protein 1 and Protection From Infection With Blood-Stage Parasites. The Journal of Infectious Diseases 208:1, pages 149-158.
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Yoshio Fujita & Hiroaki Taguchi. (2011) Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles. Chemistry Central Journal 5:1.
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Thangavelu U. Arumugam, Satoru Takeo, Tsutomu Yamasaki, Amporn Thonkukiatkul, Kazutoyo Miura, Hitoshi Otsuki, Hong Zhou, Carole A. Long, Jetsumon Sattabongkot, Jennifer Thompson, Danny W. Wilson, James G. Beeson, Julie Healer, Brendan S. Crabb, Alan F. Cowman, Motomi Torii & Takafumi Tsuboi. (2011) Discovery of GAMA, a Plasmodium falciparum Merozoite Micronemal Protein, as a Novel Blood-Stage Vaccine Candidate Antigen. Infection and Immunity 79:11, pages 4523-4532.
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Takeshi Miyata, Tetsuya Harakuni, Hideki Sugawa, Jetsumon Sattabongkot, Aki Kato, Mayumi Tachibana, Motomi Torii, Takafumi Tsuboi & Takeshi Arakawa. (2011) Adenovirus-vectored Plasmodium vivax ookinete surface protein, Pvs25, as a potential transmission-blocking vaccine. Vaccine 29:15, pages 2720-2726.
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Takeshi Miyata, Tetsuya Harakuni, Takafumi Tsuboi, Jetsumon Sattabongkot, Hideyasu Kohama, Mayumi Tachibana, Goro Matsuzaki, Motomi Torii & Takeshi Arakawa. (2010) Plasmodium vivax Ookinete Surface Protein Pvs25 Linked to Cholera Toxin B Subunit Induces Potent Transmission-Blocking Immunity by Intranasal as Well as Subcutaneous Immunization . Infection and Immunity 78:9, pages 3773-3782.
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Blaise Genton, Valérie D’Acremont, Floriana Lurati-Ruiz, Daniele Verhage, Régine Audran, Cornelus Hermsen, Liselotte Wolters, Christophe Reymond, François Spertini & Robert Sauerwein. (2010) Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with P. falciparum. Vaccine 28:40, pages 6573-6580.
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Richard Weiss, Maximilian Gabler, Thomas Jacobs, Tim-Wolf Gilberger, Josef Thalhamer & Sandra Scheiblhofer. (2010) Differential effects of C3d on the immunogenicity of gene gun vaccines encoding Plasmodium falciparum and Plasmodium berghei MSP142. Vaccine 28:28, pages 4515-4522.
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Takafumi Tsuboi, Satoru Takeo, Thangavelu U. Arumugam, Hitoshi Otsuki & Motomi Torii. (2010) The wheat germ cell-free protein synthesis system: A key tool for novel malaria vaccine candidate discovery. Acta Tropica 114:3, pages 171-176.
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Takeshi Arakawa, Mayumi Tachibana, Takeshi Miyata, Tetsuya Harakuni, Hideyasu Kohama, Yasunobu Matsumoto, Naotoshi Tsuji, Hajime Hisaeda, Anthony Stowers, Motomi Torii & Takafumi Tsuboi. (2009) Malaria Ookinete Surface Protein-Based Vaccination via the Intranasal Route Completely Blocks Parasite Transmission in both Passive and Active Vaccination Regimens in a Rodent Model of Malaria Infection. Infection and Immunity 77:12, pages 5496-5500.
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Desmond Slade, Ahmed M. Galal, Waseem Gul, Mohamed M. Radwan, Safwat A. Ahmed, Shabana I. Khan, Babu L. Tekwani, Melissa R. Jacob, Samir A. Ross & Mahmoud A. ElSohly. (2009) Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers. Bioorganic & Medicinal Chemistry 17:23, pages 7949-7957.
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Paulo Renato Rivas Totino, Cláudio Tadeu Daniel-Ribeiro & Maria de Fátima Ferreira-da-Cruz. (2009) Pro-apoptotic effects of antimalarial drugs do not affect mature human erythrocytes. Acta Tropica 112:2, pages 236-238.
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W. R. BALLOU. (2009) The development of the RTS,S malaria vaccine candidate: challenges and lessons. Parasite Immunology 31:9, pages 492-500.
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James W. Hodge, Jack Higgins & Jeffrey Schlom. (2009) Harnessing the unique local immunostimulatory properties of modified vaccinia Ankara (MVA) virus to generate superior tumor-specific immune responses and antitumor activity in a diversified prime and boost vaccine regimen. Vaccine 27:33, pages 4475-4482.
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Caroline Kulangara, Andrey V. Kajava, Giampietro Corradin & Ingrid Felger. (2009) Sequence Conservation in Plasmodium falciparum α-Helical Coiled Coil Domains Proposed for Vaccine Development. PLoS ONE 4:5, pages e5419.
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Magdalena Plebanski, Emily Locke, James W. Kazura & Ross L. Coppel. (2008) Malaria vaccines: into a mirror, darkly?. Trends in Parasitology 24:12, pages 532-536.
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