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Droxidopa in neurogenic orthostatic hypotension

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Martijn L.T.M. Müller, Uros Marusic, Miriam van Emde Boas, Daniel Weiss & Nicolaas I. Bohnen. (2019) Treatment options for postural instability and gait difficulties in Parkinson’s disease. Expert Review of Neurotherapeutics 19:12, pages 1229-1251.
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Eva Canosa-Hermida, Cristina Mondelo-García, María Elena Ferreiro-Velasco, Sebastián Salvador-de la Barrera, Antonio Montoto-Marqués, Antonio Rodríguez-Sotillo & José Ramón Vizoso-Hermida. (2018) Refractory orthostatic hypotension in a patient with a spinal cord injury: Treatment with droxidopa. The Journal of Spinal Cord Medicine 41:1, pages 115-118.
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Pearl K Jones, Brett H Shaw & Satish R Raj. (2015) Orthostatic hypotension: managing a difficult problem. Expert Review of Cardiovascular Therapy 13:11, pages 1263-1276.
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BaoLing Chen, Wanlin Yang, Yuqi Luo, Eng-King Tan & Qing Wang. (2023) Non-pharmacological and drug treatment of autonomic dysfunction in multiple system atrophy: current status and future directions. Journal of Neurology.
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Liqian Zhou, Yuzhuang Wang, Lihong Peng, Zejun Li & Xueming Luo. (2023) Identifying potential drug-target interactions based on ensemble deep learning. Frontiers in Aging Neuroscience 15.
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Hien Le HaNguyen L Nguyen. (2023) Droxidopa for refractory neurogenic orthostatic hypotension in amyloid light chain amyloidosis. American Journal of Pharmacotherapy and Pharmaceutical Sciences 2, pages 6.
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Jose-Alberto Palma & Horacio Kaufmann. 2023. Primer on the Autonomic Nervous System. Primer on the Autonomic Nervous System 721 727 .
Lauren F. Fanty & Christopher H. Gibbons. 2023. Diabetic Neuropathy. Diabetic Neuropathy 453 469 .
Bedour Jafar, Kamal Sharma, Ameera Sheikh & Paul Maertens. (2022) The Novel Use of a Synthetic Amino Acid Analog in the Management of Menkes' Disease. Journal of Pediatric Neurology 20:06, pages 415-418.
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Werner Poewe, Iva Stankovic, Glenda Halliday, Wassilios G. Meissner, Gregor K. Wenning, Maria Teresa Pellecchia, Klaus Seppi, Jose-Alberto Palma & Horacio Kaufmann. (2022) Multiple system atrophy. Nature Reviews Disease Primers 8:1.
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Gidon J. Bönhof, Christian Herder & Dan Ziegler. (2022) Diagnostic Tools, Biomarkers, and Treatments in Diabetic polyneuropathy and Cardiovascular Autonomic Neuropathy. Current Diabetes Reviews 18:5.
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Karina Sturm, Helena Jung & Andrea MaierKarina Sturm, Helena Jung & Andrea Maier. 2022. Ratgeber Ehlers-Danlos-Syndrome. Ratgeber Ehlers-Danlos-Syndrome 53 124 .
Mizuki Ito & Hirohisa Watanabe. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 3365 3373 .
Fahd S. Amjad & Sean C. Beinart. (2021) Management of Neurogenic Orthostatic Hypotension in Neurodegenerative Disorders: A Collaboration Between Cardiology and Neurology. Neurology and Therapy 10:2, pages 427-434.
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Vasiliki Katsi, Ilias Papakonstantinou, Eirini Solomou, Alexios S. Antonopoulos, Charalambos Vlachopoulos & Konstantinos Tsioufis. (2021) Management of Hypertension and Blood Pressure Dysregulation in Patients with Parkinson’s Disease—a Systematic Review. Current Hypertension Reports 23:5.
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Billie J. Matchett, Lea T. Grinberg, Panos Theofilas & Melissa E. Murray. (2021) The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease. Acta Neuropathologica 141:5, pages 631-650.
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Stuart H. Isaacson, Khashayar Dashtipour, Ali A. Mehdirad & Amanda C. Peltier. (2021) Management Strategies for Comorbid Supine Hypertension in Patients with Neurogenic Orthostatic Hypotension. Current Neurology and Neuroscience Reports 21:4.
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Elizabeth A. Coon & J. Eric Ahlskog. (2021) My Treatment Approach to Multiple System Atrophy. Mayo Clinic Proceedings 96:3, pages 708-719.
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Shuzhen Zhu, Hualing Li, Xiaoyan Xu, Yuqi Luo, Bin Deng, Xingfang Guo, Yang Guo, Wucheng Yang, Xiaobo Wei & Qing Wang. (2021) The Pathogenesis and Treatment of Cardiovascular Autonomic Dysfunction in Parkinson’s Disease: What We Know and Where to Go. Aging and disease 12:7, pages 1675.
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Ramesh K. Khurana. 2021. Autonomic Nervous System and Sleep. Autonomic Nervous System and Sleep 273 288 .
Jose-Alberto Palma & Horacio Kaufmann. 2021. Clinical Trials In Parkinson's Disease. Clinical Trials In Parkinson's Disease 323 365 .
Annie H. Ho, Christopher W. Kinter, John Wight, Anudeep R. Neelam & David Krakow. (2020) Droxidopa as an effective treatment for refractory neurogenic orthostatic hypotension and reflex bradycardia in amyloid light-chain amyloidosis: a case report. Journal of Medical Case Reports 14:1.
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Jose-Alberto Palma & Horacio Kaufmann. (2020) Clinical Trials for Neurogenic Orthostatic Hypotension: A Comprehensive Review of Endpoints, Pitfalls, and Challenges. Seminars in Neurology 40:05, pages 523-539.
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Jose Martinez, Jose-Alberto Palma, Lucy Norcliffe-Kaufmann, Amir Garakani & Horacio Kaufmann. (2020) Impact of depressive symptoms on self-perceived severity of autonomic dysfunction in multiple system atrophy: relevance for patient-reported outcomes in clinical trials. Clinical Autonomic Research 30:3, pages 215-221.
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Sayed Zia Mohammadi, Hadi Beitollahi, Massoud Kaykhaii, Nosrat Mohammadizadeh, Somayeh Tajik & Rahman Hosseinzadeh. (2020) Simultaneous determination of droxidopa and carbidopa by carbon paste electrode functionalized with NiFe2O4 nanoparticle and 2-(4-ferrocenyl-[1,2,3]triazol-1-yl)-1-(naphthalen-2-yl) ethanone. Measurement 155, pages 107522.
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Jose-Alberto Palma & Horacio Kaufmann. (2020) Management of Orthostatic Hypotension. CONTINUUM: Lifelong Learning in Neurology 26:1, pages 154-177.
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Jose-Alberto Palma & Horacio Kaufmann. (2020) Orthostatic Hypotension in Parkinson Disease. Clinics in Geriatric Medicine 36:1, pages 53-67.
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Mizuki Ito & Hirohisa Watanabe. 2020. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 9 .
Nicolaas I. Bohnen & Martijn L. T. M. Müller. 2020. Falls and Cognition in Older Persons. Falls and Cognition in Older Persons 323 341 .
S. Z. Mohammadi, H. Beitollahi, M. Kaykhaii & N. Mohammadizadeh. (2020) A Novel Electrochemical Sensor Based on Graphene Oxide Nanosheets and Ionic Liquid Binder for Differential Pulse Voltammetric Determination of Droxidopa in Pharmaceutical and Urine Samples. Russian Journal of Electrochemistry 55:12, pages 1229-1236.
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Jeremy K. Cutsforth-Gregory & Phillip A. Low. (2019) Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer. Neurology and Therapy 8:2, pages 307-324.
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Katherine E. McDonell, Brock A. Preheim, Andre’ Diedrich, James A. S. MuldowneyIIIIII, Amanda C. Peltier, David Robertson, Italo Biaggioni & Cyndya A. Shibao. (2019) Initiation of droxidopa during hospital admission for management of refractory neurogenic orthostatic hypotension in severely ill patients. The Journal of Clinical Hypertension 21:9, pages 1308-1314.
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Katherine E. McDonell, Cyndya A. Shibao, Italo Biaggioni, Adam Hartman, David Robertson & Daniel O. Claassen. (2019) Cognitive and Behavioral Changes in Patients Treated With Droxidopa for Neurogenic Orthostatic Hypotension: A Retrospective Review. Cognitive and Behavioral Neurology 32:3, pages 179-184.
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Gisela D. Puig-Carrion, Alex Reyentovich & Stuart D. Katz. (2019) Diagnosis and treatment of heart failure in hereditary transthyretin amyloidosis. Clinical Autonomic Research 29:S1, pages 45-53.
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Jose-Alberto Palma, Alejandra Gonzalez-Duarte & Horacio Kaufmann. (2019) Orthostatic hypotension in hereditary transthyretin amyloidosis: epidemiology, diagnosis and management. Clinical Autonomic Research 29:S1, pages 33-44.
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Guillaume Lamotte, Courtney Holmes, Patti Sullivan & David S. Goldstein. (2018) Substantial renal conversion of l-threo-3,4-dihydroxyphenylserine (droxidopa) to norepinephrine in patients with neurogenic orthostatic hypotension. Clinical Autonomic Research 29:1, pages 113-117.
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Janis M. Miyasaki. 2019. Neuropalliative Care. Neuropalliative Care 59 72 .
A. Shams & John E. Morley. (2018) Autonomic Neuropathy and Cardiovascular Disease in Aging. The journal of nutrition, health & aging 22:9, pages 1028-1033.
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Jose-Alberto PalmaLucy Norcliffe-KaufmannJose MartinezHoracio Kaufmann. (2018) Supine plasma NE predicts the pressor response to droxidopa in neurogenic orthostatic hypotension. Neurology 91:16.
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Gauri P. Godbole & Bhavna Aggarwal. (2018) Review of management strategies for orthostatic hypotension in older people. Journal of Pharmacy Practice and Research 48:5, pages 484-492.
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Adena Zadourian, Taylor A. Doherty, Iwona Swiatkiewicz & Pam R. Taub. (2018) Postural Orthostatic Tachycardia Syndrome: Prevalence, Pathophysiology, and Management. Drugs 78:10, pages 983-994.
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Guido Rohrer, Günter U. Höglinger & Johannes Levin. (2018) Symptomatic therapy of multiple system atrophy. Autonomic Neuroscience 211, pages 26-30.
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Jack J. Chen & L. Arthur Hewitt. (2018) Comparison of the Pharmacokinetics of Droxidopa After Dosing in the Fed Versus Fasted State and with 3-Times-Daily Dosing in Healthy Elderly Subjects. Drugs in R&D 18:1, pages 77-86.
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Jose-Alberto Palma & Horacio Kaufmann. (2018) Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies. Movement Disorders 33:3, pages 372-390.
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William B. White, L. Arthur Hewitt & Ali A. Mehdirad. (2018) Impact of the Norepinephrine Prodrug Droxidopa on the QTc Interval in Healthy Individuals. Clinical Pharmacology in Drug Development 7:3, pages 332-340.
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Italo Biaggioni, L. Arthur Hewitt, Gerald J. Rowse & Horacio Kaufmann. (2017) Integrated analysis of droxidopa trials for neurogenic orthostatic hypotension. BMC Neurology 17:1.
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Sabine Eschlböck, Gregor Wenning & Alessandra Fanciulli. (2017) Evidence-based treatment of neurogenic orthostatic hypotension and related symptoms. Journal of Neural Transmission 124:12, pages 1567-1605.
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Stephen Bacchi, Ivana Chim, Philippe Kramer & Ronald B. Postuma. (2017) Domperidone for Hypotension in Parkinson’s Disease: A Systematic Review. Journal of Parkinson's Disease 7:4, pages 603-617.
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Cyndya A. Shibao & Horacio Kaufmann. (2017) Pharmacotherapy of Cardiovascular Autonomic Dysfunction in Parkinson Disease. CNS Drugs 31:11, pages 975-989.
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Kelli Patrick & Tina Martin. (2017) Effectiveness of droxidopa compared to midodrine in standing blood pressure and orthostatic tolerance in adults with neurogenic orthostatic hypotension. JBI Database of Systematic Reviews and Implementation Reports 15:9, pages 2287-2294.
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Daniel Kremens, Mark Lew, Daniel Claassen & Brent P. Goodman. (2017) Adding droxidopa to fludrocortisone or midodrine in a patient with neurogenic orthostatic hypotension and Parkinson disease. Clinical Autonomic Research 27:S1, pages 29-31.
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Ali Mehdirad, Beverly Karabin & Fiona Gupta. (2017) Managing neurogenic orthostatic hypotension with droxidopa in a patient with Parkinson disease, atrial fibrillation, and hypertension. Clinical Autonomic Research 27:S1, pages 25-27.
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Brent P. Goodman & Fiona Gupta. (2017) Defining successful treatment of neurogenic orthostatic hypotension with droxidopa in a patient with multiple system atrophy. Clinical Autonomic Research 27:S1, pages 21-23.
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Daniel Claassen & Mark Lew. (2017) Initiating droxidopa for neurogenic orthostatic hypotension in a patient with Parkinson disease. Clinical Autonomic Research 27:S1, pages 13-14.
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Fiona Gupta, Daniel Kremens, Steven Vernino & Beverly Karabin. (2017) Managing neurogenic orthostatic hypotension in a patient presenting with pure autonomic failure who later developed Parkinson disease. Clinical Autonomic Research 27:S1, pages 9-11.
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Mark Lew & Daniel Kremens. (2017) Differential diagnosis of suspected neurogenic orthostatic hypotension in a patient with Parkinson disease. Clinical Autonomic Research 27:S1, pages 5-7.
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Horacio Kaufmann. (2017) Droxidopa for symptomatic neurogenic orthostatic hypotension: what can we learn?. Clinical Autonomic Research 27:S1, pages 1-3.
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Jose-Alberto Palma & Horacio Kaufmann. (2017) Epidemiology, Diagnosis, and Management of Neurogenic Orthostatic Hypotension. Movement Disorders Clinical Practice 4:3, pages 298-308.
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Addie Patterson & Christopher W. Hess. (2016) Accidental Overdose of Droxidopa in Parkinson's Disease‐related Orthostatic Hypotension. Movement Disorders Clinical Practice 4:2, pages 279-280.
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Yannick Vermeiren & Peter P. De Deyn. (2017) Targeting the norepinephrinergic system in Parkinson's disease and related disorders: The locus coeruleus story. Neurochemistry International 102, pages 22-32.
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Katrijn Smulders, Marian L. Dale, Patricia Carlson-Kuhta, John G. Nutt & Fay B. Horak. (2016) Pharmacological treatment in Parkinson's disease: Effects on gait. Parkinsonism & Related Disorders 31, pages 3-13.
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Horacio Kaufmann, Lucy Norcliffe-Kaufmann, L. Arthur Hewitt, Gerald J. Rowse & William B. White. (2016) Effects of the novel norepinephrine prodrug, droxidopa, on ambulatory blood pressure in patients with neurogenic orthostatic hypotension. Journal of the American Society of Hypertension 10:10, pages 819-826.
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Toshiaki Murai & Natsumi Mutoh. (2016) Sequential Addition Reaction of Sulfanylmethyllithiums and Grignard Reagents to Thioformamides Leading to the Formation of 2-Phenyl-2-sulfanylethyl Tertiary Amines. The Journal of Organic Chemistry 81:18, pages 8131-8134.
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Anthony Julius & Katelan Longfellow. (2016) Movement Disorders. Medical Clinics of North America 100:4, pages 733-761.
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Hyun-Ah Kim, Hyon-Ah Yi, Jeong-Ho Hong & Hyung Lee. (2016) Detailed Relationship Between the Pattern of Blood Pressure Change During the Valsalva Maneuver and the Degree of Orthostatic Hypotension During the Head-Up Tilt Test in Patients With Orthostatic Intolerance. Medicine 95:19, pages e3608.
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Jose-Alberto Palma, Lucy Norcliffe-Kaufmann & Horacio Kaufmann. (2016) An orthostatic hypotension mimic: The inebriation-like syndrome in Parkinson disease. Movement Disorders 31:4, pages 598-600.
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Katherine E. McDonell, Cyndya A. Shibao & Daniel O. Claassen. (2015) Clinical Relevance of Orthostatic Hypotension in Neurodegenerative Disease. Current Neurology and Neuroscience Reports 15:12.
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