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Expert Review of Anti-infective Therapy Volume 2, 2004 - Issue 1
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Drug Evaluation

Valganciclovir for the prevention and treatment of cytomegalovirus disease in immunocompromised hosts

Raymund R Razonable Mayo Clinic College of Medicine, Mayo Foundation Scholar, Division of Infectious Diseases, Mayo Clinic and Foundation, Rochester, Minnesota, MN 55905. [email protected]
&
Carlos V Paya Mayo Clinic College of Medicine, Mayo Foundation Scholar, Division of Infectious Diseases, Mayo Clinic and Foundation, Rochester, Minnesota, MN 55905. [email protected]
Pages 27-41 | Published online: 10 Jan 2014

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Qiu-Yue Li, John van den Anker, Yue-E Wu, Guo-Xiang Hao & Wei Zhao. (2023) Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring. Expert Review of Clinical Pharmacology 16:8, pages 727-739.
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C. L. Abad & R. R. Razonable. (2017) Treatment of alpha and beta herpesvirus infections in solid organ transplant recipients. Expert Review of Anti-infective Therapy 15:2, pages 93-110.
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Elena Yu Enioutina, Jonathan E Constance, Chris Stockmann, Matthew W Linakis, Tian Yu, Joseph E Rower, Alfred H Balch & Catherine M Sherwin. (2015) Pharmacokinetic considerations in the use of antivirals in neonates. Expert Opinion on Drug Metabolism & Toxicology 11:12, pages 1861-1878.
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Navjit K Sanghera & Tricia L Newman. (2010) Cytomegaloviral retinitis from chronic immunosuppression following solid organ transplant surgery. Clinical and Experimental Optometry 93:4, pages 261-263.
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Kabeya Mwintshi & Daniel C Brennan. (2007) Prevention and management of cytomegalovirus infection in solid-organ transplantation. Expert Review of Anti-infective Therapy 5:2, pages 295-304.
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Suzanne Luck, Mike Sharland, Paul Griffiths & Sian M Jenkins. (2006) Advances in the antiviral therapy of herpes virus infection in children. Expert Review of Anti-infective Therapy 4:6, pages 1005-1020.
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Isabel Gomez-Orellana. (2005) Strategies to improve oral drug bioavailability. Expert Opinion on Drug Delivery 2:3, pages 419-433.
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Articles from other publishers (35)

Zachary A. Yetmar, Dustin Duffy, Byron H. Smith, Holenarasipur R. Vikram, Lisa Brumble, Andrew H. Limper & Elena Beam. (2023) Risk factors and outcomes of Pneumocystis pneumonia in solid organ transplant recipients: Impact of posttransplant lymphoproliferative disorder . Clinical Transplantation.
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Vuyolwethu Khwaza, Buhle Buyana, Xhamla Nqoro, Sijongesonke Peter, Zintle Mbese, Zizo Feketshane, Sibusiso Alven & Blessing A. Aderibigbe. 2023. Viral Infections and Antiviral Therapies. Viral Infections and Antiviral Therapies 407 492 .
Filipa Silva, Klaus Nunes Ficher, Laila Viana, Inês Coelho, Juliana Toniato Rezende, Daniel Wagner, Maria Lúcia Vaz, Renato Foresto, Helio Tedesco Silva Junior & José Medina Pestana. (2022) Presumed cytomegalovirus retinitis late after kidney transplant. Brazilian Journal of Nephrology 44:3, pages 457-461.
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Sing Leung Lui, Desmond Yap, Vincent Cheng, Tak Mao Chan & Kwok Yung Yuen. (2019) Clinical practice guidelines for the provision of renal service in Hong Kong: Infection Control in Renal Service. Nephrology 24:S1, pages 98-129.
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Ayman F. El‐Kattan. 2017. Oral Bioavailability Assessment. Oral Bioavailability Assessment 139 171 .
Sanjay K. Yadav, Sanjiv Saigal, Narendra S. Choudhary, Sujit Saha, Navin Kumar & Arvinder S. Soin. (2017) Cytomegalovirus Infection in Liver Transplant Recipients: Current Approach to Diagnosis and Management. Journal of Clinical and Experimental Hepatology 7:2, pages 144-151.
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M. Veronica Dioverti & Raymund R. Razonable. 2016. Diagnostic Microbiology of the Immunocompromised Host. Diagnostic Microbiology of the Immunocompromised Host 97 125 .
M. Veronica Dioverti & Raymund R. Razonable. (2016) Cytomegalovirus. Microbiology Spectrum 4:4.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 687 736 .
Raymund R. Razonable & Ajit P. Limaye. 2016. Transplant Infections. Transplant Infections 441 475 .
Jackrapong Bruminhent. (2014) Management of cytomegalovirus infection and disease in liver transplant recipients. World Journal of Hepatology 6:6, pages 370.
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R.R. Razonable & A. Humar. (2013) Cytomegalovirus in Solid Organ Transplantation. American Journal of Transplantation 13, pages 93-106.
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Marie‐Louise Vachon, Ponni Perumalswami & Douglas T. Dieterich. 2011. Schiff's Diseases of the Liver. Schiff's Diseases of the Liver 1060 1082 .
Raymund R. Razonable. (2011) Antiviral Drugs for Viruses Other Than Human Immunodeficiency Virus. Mayo Clinic Proceedings 86:10, pages 1009-1026.
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Mike Sharland, Suzanne Luck, Paul Griffiths & Mark Cotton. 2011. Hot Topics in Infection and Immunity in Children VII. Hot Topics in Infection and Immunity in Children VII 243 260 .
Horst Welker, Mahdi Farhan, Atul Humar & Carla Washington. (2010) Ganciclovir Pharmacokinetic Parameters Do Not Change When Extending Valganciclovir Cytomegalovirus Prophylaxis From 100 to 200 Days. Transplantation 90:12, pages 1414-1419.
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Raymund R. Razonable. 2010. Emerging Infections 9. Emerging Infections 9 129 167 .
A.J.M. Saleh, Fahad Al Mohareb, Fahad Al Rabiah, Naeem Chaudhri, Fahad Al Sharif, Hazzaa Al Zahrani, Said Yousuf Mohamed, Moosa Patel, Walid Rasheed, Zubeir Nurgat, Mohammad Bakr, Shad Ahmed, Syed Zaidi, Amr Nassar, Khaled Ibrahim, Hail Al Abdely & Mahmoud Aljurf. (2010) High efficacy and low toxicity of short-course oral valganciclovir as pre-emptive therapy for hematopoietic stem cell transplant cytomegalovirus infection. Hematology/Oncology and Stem Cell Therapy 3:3, pages 116-120.
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Sang-Oh Lee. (2010) Current concepts on cytomegalovirus infection after liver transplantation. World Journal of Hepatology 2:9, pages 325.
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Raymund R Razonable. (2010) Immune-based therapies for cytomegalovirus infection. Immunotherapy 2:1, pages 117-130.
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R.L. Brady, K. Green, C. Frei & P. Maxwell. (2009) Oral ganciclovir versus valganciclovir for cytomegalovirus prophylaxis in high-risk liver transplant recipients. Transplant Infectious Disease 11:2, pages 106-111.
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Chandra Prakash & Alfin D. N. Vaz. 2008. Nuclear Receptors in Drug Metabolism. Nuclear Receptors in Drug Metabolism 1 41 .
Cari R. Sloma, Thomas E. Grys & Raymund R. Razonable. 2008. Diagnostic Microbiology of the Immunocompromised Host. Diagnostic Microbiology of the Immunocompromised Host 69 89 .
Allison L. Baroco & Edward C. Oldfield. (2008) Gastrointestinal cytomegalovirus disease in the immunocompromised patient. Current Gastroenterology Reports 10:4, pages 409-416.
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A.J. Eid, S.J. Bakri, S. Kijpittayarit & R.R. Razonable. (2008) Clinical features and outcomes of cytomegalovirus retinitis after transplantation. Transplant Infectious Disease 10:1, pages 13-18.
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H. SealeD.E. DwyerJ.R. ChapmanC.R. MacIntyre. (2008) Cytomegalovirus Disease Amongst Renal Transplant Recipients in Australia and New Zealand. Virology: Research and Treatment 1, pages VRT.S920.
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Raymund-Rabe Razonable. (2008) Cytomegalovirus infection after liver transplantation: Current concepts and challenges. World Journal of Gastroenterology 14:31, pages 4849.
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Luis Ostrosky-Zeichner & John H. Rex. 2008. Critical Care Medicine. Critical Care Medicine 1089 1109 .
R.K Avery. (2007) Valganciclovir Versus IV Ganciclovir for Therapy of Cytomegalovirus Viremia: Has Victory Been Achieved?. American Journal of Transplantation 7:9, pages 2062-2063.
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Hans Maag. 2007. Prodrugs. Prodrugs 1377 1386 .
Nahed Abdel-Haq, Pimpanada Chearskul, Hossam Al-Tatari & Basim Asmar. (2006) New antiviral agents. The Indian Journal of Pediatrics 73:4, pages 313-321.
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A. Bordils, J. Sanchez Plumed, D. Ramos, I. Beneyto, V. Mascarós, J.M. Molina, J. Cordoba, J. Garcı́a & J.M. Crúz. (2005) Comparison of Quantitative PCR and Antigenemia in Cytomegalovirus Infection in Renal Transplant Recipients. Transplantation Proceedings 37:9, pages 3756-3759.
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Cem Cengiz, James S. Park, Neeraj Saraf & Douglas T. Dieterich. (2005) HIV and Liver Diseases: Recent Clinical Advances. Clinics in Liver Disease 9:4, pages 647-666.
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S. Cesaro, X. Zhou, C. Manzardo, D. Buonfrate, R. Cusinato, G. Tridello, C. Mengoli, G. Palù & C. Messina. (2005) Cidofovir for cytomegalovirus reactivation in pediatric patients after hematopoietic stem cell transplantation. Journal of Clinical Virology 34:2, pages 129-132.
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Atul Humar. (2005) Valganciclovir for cytomegalovirus prevention and treatment. Therapy 2:3, pages 333-341.
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