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Key Paper Evaluation

Is there really no benefit to combination therapy with colistin?

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Pages 881-884 | Published online: 10 Jan 2014

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Alessandra Oliva, Stefania Garzoli, Massimiliano De Angelis, Carolina Marzuillo, Vincenzo Vullo, Claudio Mastroianni & Rino Ragno. (2019) In-Vitro Evaluation of Different Antimicrobial Combinations with and without Colistin Against Carbapenem-Resistant Acinetobacter Baumannii. Molecules 24:5, pages 886.
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Xueli Zhang, Fengmei Guo, Hua Shao & Xiao Zheng. (2017) Clinical translation of polymyxin-based combination therapy: Facts, challenges and future opportunities. Journal of Infection 74:2, pages 118-130.
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Federico Perez & Robert A. Bonomo. 2017. Antimicrobial Drug Resistance. Antimicrobial Drug Resistance 923 935 .
Justin R. Lenhard, Roger L. Nation & Brian T. Tsuji. (2016) Synergistic combinations of polymyxins. International Journal of Antimicrobial Agents 48:6, pages 607-613.
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N. L. Parchem, K. A. Bauer, C. H. Cook, J. E. Mangino, C. D. Jones, K. Porter & C. V. Murphy. (2016) Colistin combination therapy improves microbiologic cure in critically ill patients with multi-drug resistant gram-negative pneumonia. European Journal of Clinical Microbiology & Infectious Diseases 35:9, pages 1433-1439.
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Bing Fan, Jie Guan, Xiumei Wang & Yulong Cong. (2016) Activity of Colistin in Combination with Meropenem, Tigecycline, Fosfomycin, Fusidic Acid, Rifampin or Sulbactam against Extensively Drug-Resistant Acinetobacter baumannii in a Murine Thigh-Infection Model. PLOS ONE 11:6, pages e0157757.
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Zhijin Chen, Yu Chen, Yaogao Fang, Xiaotian Wang, Yanqing Chen, Qingsong Qi, Fang Huang & Xungang Xiao. (2015) Meta-analysis of colistin for the treatment of Acinetobacter baumannii infection. Scientific Reports 5:1.
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A. Batirel, I. I. Balkan, O. Karabay, C. Agalar, S. Akalin, O. Alici, E. Alp, F. A. Altay, N. Altin, F. Arslan, T. Aslan, N. Bekiroglu, S. Cesur, A. D. Celik, M. Dogan, B. Durdu, F. Duygu, A. Engin, D. O. Engin, I. Gonen, E. Guclu, T. Guven, C. A. Hatipoglu, S. Hosoglu, M. K. Karahocagil, A. U. Kilic, B. Ormen, D. Ozdemir, S. Ozer, N. Oztoprak, N. Sezak, V. Turhan, N. Turker & H. Yilmaz. (2014) Comparison of colistin–carbapenem, colistin–sulbactam, and colistin plus other antibacterial agents for the treatment of extremely drug-resistant Acinetobacter baumannii bloodstream infections. European Journal of Clinical Microbiology & Infectious Diseases 33:8, pages 1311-1322.
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