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Editorial

How plausible is a link between HSV-1 infection and Alzheimer’s disease?

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Keep up to date with the latest research on this topic with citation updates for this article.

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Yiliang Wang, Jiaoyan Jia, Yun Wang, Feng Li, Xiaowei Song, Shurong Qin, Zhaoyang Wang, Kaio Kitazato & Yifei Wang. (2019) Roles of HSV-1 infection-induced microglial immune responses in CNS diseases: friends or foes?. Critical Reviews in Microbiology 45:5-6, pages 581-594.
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Simone Agostini, Roberta Mancuso, Francesca Baglio & Mario Clerici. (2017) A protective role for herpes simplex virus type-1-specific humoral immunity in Alzheimer’s Disease. Expert Review of Anti-infective Therapy 15:2, pages 89-91.
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Articles from other publishers (20)

Anil Yirün, Deniz Arca Çakır, Sonia Sanajou, Selinay Başak Erdemli Köse, Aylin Balcı Özyurt, Dilara Zeybek, Özlem Bozdemir, Terken Baydar & Pinar Erkekoglu. (2023) Evaluation of the effects of herpes simplex glycoprotein B on complement system and cytokines in in vitro models of Alzheimer's disease. Journal of Applied Toxicology 43:9, pages 1368-1378.
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Pu Huang, Xu Wang, Mengyue Lei, Ying Ma, Hongli Chen, Jing Sun, Yunzhang Hu & Jiandong Shi. (2023) Metabolomics Profiles Reveal New Insights of Herpes Simplex Virus Type 1 Infection. International Journal of Molecular Sciences 24:2, pages 1521.
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Taner Akyol, Ahmet Cumhur Dülger, Yaren Dirik, Demet Şeker, Vedat Ataman Serim, Hüsniye Aylin Hakyemez, Tuğrul Kesicioğlu, Muhammed Ali Ayvaz & Merih Şimşek. (2022) Prevalence of Helicobacter pylori infection in patients with Dementia who underwent Percutaneous Endoscopic Gastrostomy (PEG) and the effect of preventive single dose ceftrixone plus pantaprazole therapy on Helicobacter pylori infection. Medical Science and Discovery 9:3, pages 149-152.
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Ruth F. Itzhaki. (2021) Overwhelming Evidence for a Major Role for Herpes Simplex Virus Type 1 (HSV1) in Alzheimer’s Disease (AD); Underwhelming Evidence against. Vaccines 9:6, pages 679.
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Zhongyuan Li, Ying Yang, Miaomiao Liu, Chenghua Zhang, Junjing Shao, Xuewen Hou, Jingzhen Tian & Qinghua Cui. (2021) A comprehensive review on phytochemistry, bioactivities, toxicity studies, and clinical studies on Ficus carica Linn. leaves. Biomedicine & Pharmacotherapy 137, pages 111393.
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Rhutuja Khokale, Ayesha Kang, Keri-Ann R Buchanan-Peart, Maxine L Nelson, Oluwatayo J Awolumate & Ivan Cancarevic. (2020) Alzheimer's Gone Viral: Could Herpes Simplex Virus Type-1 Be Stealing Your Memories?. Cureus.
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Harpreet Kaur, Kumi Nagamoto-Combs, Svetlana Golovko, Mikhail Y. Golovko, Marilyn G. Klug & Colin Kelly Combs. (2020) Probiotics ameliorate intestinal pathophysiology in a mouse model of Alzheimer’s disease. Neurobiology of Aging 92, pages 114-134.
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Dejan Stojković, Marina Kostić, Marija Smiljković, Milena Aleksić, Perica Vasiljević, Miloš Nikolić & Marina Soković. (2020) Linking Antimicrobial Potential of Natural Products Derived from Aquatic Organisms and Microbes Involved in Alzheimer’s Disease - A Review. Current Medicinal Chemistry 27:26, pages 4372-4391.
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C. V. Sobol. (2019) Role of Microbiota in Neurodegenerative Diseases. Russian Journal of Developmental Biology 49:6, pages 297-313.
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Li Lin, Li Juan Zheng & Long Jiang Zhang. (2018) Neuroinflammation, Gut Microbiome, and Alzheimer’s Disease. Molecular Neurobiology 55:11, pages 8243-8250.
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Antero Salminen, Kai Kaarniranta & Anu Kauppinen. (2018) The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer’s disease. Cellular and Molecular Life Sciences 75:17, pages 3099-3120.
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Abolghasem Tohidpour, Andrey V. Morgun, Elizaveta B. Boitsova, Natalia A. Malinovskaya, Galina P. Martynova, Elena D. Khilazheva, Natalia V. Kopylevich, Galina E. Gertsog & Alla B. Salmina. (2017) Neuroinflammation and Infection: Molecular Mechanisms Associated with Dysfunction of Neurovascular Unit. Frontiers in Cellular and Infection Microbiology 7.
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Charlotte Warren-Gash, Harriet Forbes, Judith Breuer, Andrew C Hayward, Angelique Mavrodaris, Basil H Ridha, Martin Rossor, Sara L Thomas & Liam Smeeth. (2017) Association between human herpesvirus infections and dementia or mild cognitive impairment: a systematic review protocol. BMJ Open 7:6, pages e016522.
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Simone Agostini, Roberta Mancuso, Francesca Baglio, Monia Cabinio, Ambra Hernis, Andrea Saul Costa, Elena Calabrese, Raffaello Nemni & Mario Clerici. (2016) High avidity HSV-1 antibodies correlate with absence of amnestic Mild Cognitive Impairment conversion to Alzheimer’s disease. Brain, Behavior, and Immunity 58, pages 254-260.
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Jianhui Wang, Fuqiang Ye, Xiaorui Cheng, Xiaorui Zhang, Feng Liu, Gang Liu, Ming Ni, Shanyi Qiao, Wenxia Zhou & Yongxiang Zhang. (2016) The Effects of LW-AFC on Intestinal Microbiome in Senescence-Accelerated Mouse Prone 8 Strain, a Mouse Model of Alzheimer’s Disease. Journal of Alzheimer's Disease 53:3, pages 907-919.
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Filip Scheperjans. (2016) Can microbiota research change our understanding of neurodegenerative diseases?. Neurodegenerative Disease Management 6:2, pages 81-85.
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Simone Agostini, Roberta Mancuso, Francesca Baglio, Monia Cabinio, Ambra Hernis, Franca Rosa Guerini, Elena Calabrese, Raffaello Nemni & Mario Clerici. (2015) Lack of Evidence for a Role of HHV-6 in the Pathogenesis of Alzheimer’s Disease. Journal of Alzheimer's Disease 49:1, pages 229-235.
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Ruth Alonso, Diana Pisa, Alberto Rábano, Izaskun Rodal & Luis Carrasco. (2015) Cerebrospinal Fluid from Alzheimer’s Disease Patients Contains Fungal Proteins and DNA. Journal of Alzheimer's Disease 47:4, pages 873-876.
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Wei Xu, Lan Tan & Jin-Tai Yu. (2014) The Role of PICALM in Alzheimer’s Disease. Molecular Neurobiology 52:1, pages 399-413.
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Roberta Mancuso, Francesca Baglio, Simone Agostini, Monia Cabinio Agostini, Maria M. Laganà, Ambra Hernis, Nicolò Margaritella, Franca R. Guerini, Milena Zanzottera, Raffaello Nemni & Mario Clerici. (2014) Relationship between herpes simplex virus-1-specific antibody titers and cortical brain damage in Alzheimer’s disease and amnestic mild cognitive impairment. Frontiers in Aging Neuroscience 6.
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