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Impact of special patient populations on the pharmacokinetics of echinocandins

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Mateusz Szymański, Sandra Chmielewska, Urszula Czyżewska, Marta Malinowska & Adam Tylicki. (2022) Echinocandins – structure, mechanism of action and use in antifungal therapy. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 876-894.
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Joseph Berthier, Mehdi Benmameri, François-Ludovic Sauvage, Gabin Fabre, Benjamin Chantemargue, Hélène Arnion, Pierre Marquet, Patrick Trouillas, Nicolas Picard & Franck Saint-Marcoux. (2021) MRP4 is responsible for the efflux transport of mycophenolic acid β-d glucuronide (MPAG) from hepatocytes to blood. Xenobiotica 51:1, pages 105-114.
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Seyed MohammadReza Hashemian, Tayebeh Farhadi & Ali Akbar Velayati. (2020) Caspofungin: a review of its characteristics, activity, and use in intensive care units. Expert Review of Anti-infective Therapy 18:12, pages 1213-1220.
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Siang Fei Yeoh, Tae Jin Lee, Ka Lip Chew, Stephen Lin, Dennis Yeo & Sajita Setia. (2018) Echinocandins for management of invasive candidiasis in patients with liver disease and liver transplantation. Infection and Drug Resistance 11, pages 805-819.
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Javier Martínez-Casanova, Nuria Carballo, Sonia Luque, Luisa Sorli & Santiago Grau. (2018) Posaconazole achieves prompt recovery of voriconazole-induced liver injury in a case of invasive aspergillosis. Infection and Drug Resistance 11, pages 317-321.
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Ya-Lin Chang, Shang-Jie Yu, Joseph Heitman, Melanie Wellington & Ying-Lien Chen. (2017) New facets of antifungal therapy. Virulence 8:2, pages 222-236.
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Yazed S Alsowaida, Ahmad Alamer, Abrar K Thabit, Abdulaziz S Almulhim, Muneerah M Aleissa, Alireza Kalbasi, Khaled Eljaaly, Thamer A Almangour & Brian L Erstad. (2023) Echinocandin exposures in obese patients: A scoping review and clinical perspectives. American Journal of Health-System Pharmacy 80:8, pages 503-517.
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Qianting Yang, Tao Zhang, Ying Zhang, Dan Sun, Xiaowei Zheng, Qian Du, Xue Wang, Xiaoliang Cheng, Jianfeng Xing & Yalin Dong. (2022) The recommended dosage regimen for caspofungin in patients with higher body weight or hypoalbuminaemia will result in low exposure: Five years of data based on a population pharmacokinetic model and Monte-Carlo simulations. Frontiers in Pharmacology 13.
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Faruk Ekinci, Dincer Yildizdas, Ozden Ozgur Horoz, Ozlem Ozgur Gundeslioglu & Derya Alabaz. (2022) Treatment of Candida urinary tract infections with micafungin in children . Pediatrics International 64:1.
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Pekka Ylipalosaari, Tero I. Ala‐Kokko, Juha Koskenkari, Jouko J. Laurila, Sirpa Ämmälä & Hannu Syrjälä. (2021) Use and outcome of empiric echinocandins in critically ill patients. Acta Anaesthesiologica Scandinavica 65:7, pages 944-951.
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Philipp Koehler, Matteo Bassetti, Arunaloke Chakrabarti, Sharon C A Chen, Arnaldo Lopes Colombo, Martin Hoenigl, Nikolay Klimko, Cornelia Lass-Flörl, Rita O Oladele, Donald C Vinh, Li-Ping Zhu, Boris Böll, Roger Brüggemann, Jean-Pierre Gangneux, John R Perfect, Thomas F Patterson, Thorsten Persigehl, Jacques F Meis, Luis Ostrosky-Zeichner, P Lewis White, Paul E Verweij & Oliver A Cornely. (2021) Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance. The Lancet Infectious Diseases 21:6, pages e149-e162.
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Shubai Zhong, Xu Zhu, Limei Zhao, Yan Song, Jian Yu, Zhen Zheng & Bin Zang. (2021) Optimization of Micafungin Dosage for Chinese Patients with Sepsis in the Intensive Care Unit Based on a Population Pharmacokinetic-Pharmacodynamic Analysis. Pharmaceutical Research 38:1, pages 67-77.
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Alberto Ferrarese, Annamaria Cattelan, Umberto Cillo, Enrico Gringeri, Francesco Paolo Russo, Giacomo Germani, Martina Gambato, Patrizia Burra & Marco Senzolo. (2020) Invasive fungal infection before and after liver transplantation. World Journal of Gastroenterology 26:47, pages 7485-7496.
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Xiaoqing Liu, Dongdong Liu, Ying Pan & Yimin Li. (2020) Pharmacokinetic/pharmacodynamics variability of echinocandins in critically ill patients: A systematic review and meta‐analysis. Journal of Clinical Pharmacy and Therapeutics 45:6, pages 1207-1217.
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A. Gómez-López. (2020) Antifungal therapeutic drug monitoring: focus on drugs without a clear recommendation. Clinical Microbiology and Infection 26:11, pages 1481-1487.
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Bing Zhu, Yuanzhen Dong, Jie Ma, Minwei Chen, Sida Ruan, Wenjie Zhao & Jun Feng. (2020) The synthesis and activity evaluation of N‐acylated analogs of echinocandin B with improved solubility and lower toxicity. Journal of Peptide Science 26:11.
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Qianting Yang, Tao Zhang, Dan Zhao, Ying Zhang, Yuzhu Dong, Dan Sun, Qian Du, Jing Zheng, Haidong Lu & Yalin Dong. (2019) Factors influencing caspofungin plasma concentrations in kidney transplant patients with high incidence of invasive fungal infections. Journal of Clinical Pharmacy and Therapeutics 45:1, pages 72-80.
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Christian Koch, Emmanuel Schneck, Christoph Arens, Melanie Markmann, Michael Sander, Michael Henrich, Markus A. Weigand & Christoph Lichtenstern. (2019) Hemodynamic changes in surgical intensive care unit patients undergoing echinocandin treatment. International Journal of Clinical Pharmacy 42:1, pages 72-79.
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Laura Ferreras-Antolín, Adam Irwin, Ayad Atra, Alicia Dermirjian, Simon B. Drysdale, Marieke Emonts, Paddy McMaster, Stephane Paulus, Sanjay Patel, Sally Kinsey, Stefania Vergnano, Elisabeth Whittaker & Adilia Warris. (2019) Neonatal Antifungal Consumption Is Dominated by Prophylactic Use; Outcomes From The Pediatric Antifungal Stewardship. The Pediatric Infectious Disease Journal 38:12, pages 1219-1223.
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Ashrit Multani, Aruna K. Subramanian & Anne Y. Liu. (2019) Successful eradication of chronic symptomatic Candida krusei urinary tract infection with increased dose micafungin in a liver and kidney transplant recipient: Case report and review of the literature . Transplant Infectious Disease 21:4.
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P. Marie Arockianathan, Monika Mishra & Rituraj Niranjan. (2019) Recent Status and Advancements in the Development of Antifungal Agents: Highlights on Plant and Marine Based Antifungals. Current Topics in Medicinal Chemistry 19:10, pages 812-830.
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Christian Koch, Jennifer Jersch, Emmanuel Schneck, Fabian Edinger, Hagen Maxeiner, Florian Uhle, Markus A. Weigand, Melanie Markmann, Michael Sander & Michael Henrich. (2018) Caspofungin Modulates Ryanodine Receptor-Mediated Calcium Release in Human Cardiac Myocytes. Antimicrobial Agents and Chemotherapy 62:11.
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Qian-ting Yang, Ya-jing Zhai, Lu Chen, Tao Zhang, Yan Yan, Ti Meng, Lei-chao Liu, Li-mei Chen, Xue Wang & Ya-lin Dong. (2018) Whole-body physiology-based pharmacokinetics of caspofungin for general patients, intensive care unit patients and hepatic insufficiency patients. Acta Pharmacologica Sinica 39:9, pages 1533-1543.
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Nicolas Venisse. 2018. Pharmacologie des Anti-Infectieux. Pharmacologie des Anti-Infectieux 121 126 .
Roger J. M. Brüggemann, Dylan W. de Lange & Jan-Willem C. Alffenaar. 2018. Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill. Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill 213 238 .
Marianna Ventura, Roberta Michelini, Nunzia Decembrino, Mariadelfina Molinaro, Marco Zecca & Simona De Gregori. (2017) High Performance Liquid Chromatography–Tandem Mass Spectrometry Method for Simultaneous Quantification of Caspofungin, Anidulafungin and Micafungin in Human Plasma for Feasible Applications in Pediatric Haematology/Oncology. Chromatographia 80:7, pages 1035-1045.
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C. C. Chang, M. A. Slavin & S. C.-A. Chen. (2017) New developments and directions in the clinical application of the echinocandins. Archives of Toxicology 91:4, pages 1613-1621.
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Tyson E. Dietrich, Carolyn J. Pfeifer, Kelsey E. Aker & Scott J. Bergman. (2017) Antifungal Dosing Strategies for Critically Ill Patients. Current Fungal Infection Reports 11:1, pages 5-15.
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Vincent J. C. Lempers, Jeroen J. M. W. van den Heuvel, Frans G. M. Russel, Rob E. Aarnoutse, David M. Burger, Roger J. Brüggemann & Jan B. Koenderink. (2016) Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP. Antimicrobial Agents and Chemotherapy 60:6, pages 3372-3379.
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Vincent J. Lempers & Roger J. Brüggemann. (2016) Antifungal therapy: drug–drug interactions at your fingertips. Journal of Antimicrobial Chemotherapy 71:2, pages 285-289.
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Christian Koch, Matthias Wolff, Michael Henrich, Markus A. Weigand, Christoph Lichtenstern & Florian Uhle. (2016) Cardiac Effects of Echinocandins in Endotoxemic Rats. Antimicrobial Agents and Chemotherapy 60:1, pages 301-306.
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Tara Anderson. 2016. Drug Dosing in Obesity. Drug Dosing in Obesity 97 107 .
Vincent JC Lempers, Lisa C Martial, Michiel F Schreuder, Nicole M Blijlevens, David M Burger, Rob E Aarnoutse & Roger JM Brüggemann. (2015) Drug-interactions of azole antifungals with selected immunosuppressants in transplant patients: strategies for optimal management in clinical practice. Current Opinion in Pharmacology 24, pages 38-44.
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