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Phage approved in food, why not as a therapeutic?

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Md. Rashedul Islam, Carlos E. Martinez-Soto, Janet T. Lin, Cezar M. Khursigara, Shai Barbut & Hany Anany. (2023) A systematic review from basics to omics on bacteriophage applications in poultry production and processing. Critical Reviews in Food Science and Nutrition 63:18, pages 3097-3129.
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Tesfaye Kassa. (2021) Bacteriophages Against Pathogenic Bacteria and Possibilities for Future Application in Africa. Infection and Drug Resistance 14, pages 17-31.
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Md. Moinuddin Sheam, Shifath Bin Syed, Zulkar Nain, Swee- Seong Tang, Dipak Kumar Paul, Kazi Rejvee Ahmed & Sudhangshu Kumar Biswas. (2020) Community-acquired pneumonia: aetiology, antibiotic resistance and prospects of phage therapy. Journal of Chemotherapy 32:8, pages 395-410.
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Graça Pinto, Carina Almeida & Joana Azeredo. (2020) Bacteriophages to control Shiga toxin-producing E. coli – safety and regulatory challenges. Critical Reviews in Biotechnology 40:8, pages 1081-1097.
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Articles from other publishers (59)

Xiaoming Yuan, Zhenjun Zhu, Zhichao Huang, Shan Yu, Hui Jin, Bo Chen, Shubo Yu, Liang Xue, Moutong Chen, Jumei Zhang, Juan Wang, Qingping Wu & Yu Ding. (2023) Engineered lytic phage of Bacillus cereus and its application in milk. International Journal of Food Microbiology 405, pages 110339.
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Claire N. Schamp, Nitin Dhowlaghar, Lauren K. Hudson, Daniel W. Bryan, Qixin Zhong, Elizabeth M. Fozo, Ahmed Gaballa, Martin Wiedmann & Thomas G. Denes. (2023) Selection of mutant Listeria phages under food-relevant conditions can enhance application potential . Applied and Environmental Microbiology 89:10.
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Maryanne Kuek, Sarah K. McLean & Enzo A. Palombo. (2023) Control of Escherichia coli in Fresh-Cut Mixed Vegetables Using a Combination of Bacteriophage and Carvacrol. Antibiotics 12:11, pages 1579.
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Subhash Lal Karn, Mayank Gangwar, Rajesh Kumar, Satyanam Kumar Bhartiya & Gopal Nath. (2023) Phage therapy: a revolutionary shift in the management of bacterial infections, pioneering new horizons in clinical practice, and reimagining the arsenal against microbial pathogens. Frontiers in Medicine 10.
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Su-Hyeon Kim, Heejeong Lee & Mi-Kyung Park. (2023) Isolation, characterization, and application of a novel, lytic phage vB_SalA_KFSST3 with depolymerase for the control of Salmonella and its biofilm on cantaloupe under cold temperature. Food Research International 172, pages 113062.
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Lan Yao, Yinli Bao, Jiangang Hu, Beibei Zhang, Zhiyang Wang, Xinyu Wang, Weiqi Guo, Di Wang, Jingjing Qi, Mingxing Tian, Yanqing Bao, Haihua Li & Shaohui Wang. (2023) A lytic phage to control multidrug-resistant avian pathogenic Escherichia coli (APEC) infection. Frontiers in Cellular and Infection Microbiology 13.
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Rasti Sahu, Ankit Kumar Singh, Adarsh Kumar, Kuldeep Singh & Pradeep Kumar. (2023) Bacteriophages Concept and Applications: A Review on Phage Therapy. Current Pharmaceutical Biotechnology 24:10, pages 1245-1264.
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Lokitha R., Namitha Nandakumar, Harish K., Arulmozhi P., Aarthi Jayakumar, Anbarasi K. & Benedict Paul C.. (2023) Antimicrobial Therapeutic Strategies for Enterococcus faecalis In Dental Infections - Past, Present and Future. Anti-Infective Agents 21:3.
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Yanqi Li, Shune Xiao & Guangtao Huang. (2023) Acinetobacter baumannii Bacteriophage: Progress in Isolation, Genome Sequencing, Preclinical Research, and Clinical Application. Current Microbiology 80:6.
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Su-Hyeon Kim & Mi-Kyung Park. (2023) Isolation and characterization of a lytic Salmonella Typhimurium-specific phage as a potential biofilm control agent. Korean Journal of Food Preservation 30:1, pages 42-51.
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Ana Mafalda Pinto, Marisol Dias, Lorenzo M. Pastrana, Miguel A. Cerqueira & Sanna Sillankorva. 2023. Advances in Biomedical Polymers and Composites. Advances in Biomedical Polymers and Composites 769 793 .
Baptiste Arbez, Marion Gardette, Christophe Gantzer, Neus Vilà, Isabelle Bertrand & Sofiane El-Kirat-Chatel. (2022) Deciphering the role of monosaccharides during phage infection of Staphylococcus aureus. Nano Research 15:10, pages 9234-9242.
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Mateusz Wdowiak, Jan Paczesny & Sada Raza. (2022) Enhancing the Stability of Bacteriophages Using Physical, Chemical, and Nano-Based Approaches: A Review. Pharmaceutics 14:9, pages 1936.
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Nathaniel C. Esteves & Birgit E. Scharf. (2022) Flagellotropic Bacteriophages: Opportunities and Challenges for Antimicrobial Applications. International Journal of Molecular Sciences 23:13, pages 7084.
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Yicun Wang, Guangxin Zhang, Lili Zhong, Min Qian, Meng Wang & Ranji Cui. (2022) Filamentous bacteriophages, natural nanoparticles, for viral vaccine strategies. Nanoscale 14:16, pages 5942-5959.
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Malak AlmutairiMohammed ImamNouf AlammariRadwan HafizFaizal PatelSulaiman Alajel. (2022) Using Phages to Reduce Salmonella Prevalence in Chicken Meat: A Systematic Review . PHAGE 3:1, pages 15-27.
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Leina Dou, Yingjie Zhang, Yuchen Bai, Yuan Li, Minggang Liu, Shibei Shao, Qing Li, Wenbo Yu, Jianzhong Shen & Zhanhui Wang. (2022) Advances in Chicken IgY-Based Immunoassays for the Detection of Chemical and Biological Hazards in Food Samples. Journal of Agricultural and Food Chemistry 70:4, pages 976-991.
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Hui Yue, Yan Li, Mingying Yang & Chuanbin Mao. (2021) T7 Phage as an Emerging Nanobiomaterial with Genetically Tunable Target Specificity. Advanced Science 9:4.
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Jian Li, Feng Zhao, Wenyao Zhan, Zhiqi Li, Liang Zou & Qi Zhao. (2021) Challenges for the application of bacteriophages as effective antibacterial agents in the food industry. Journal of the Science of Food and Agriculture 102:2, pages 461-471.
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Helen N. Onyeaka & Ozioma F. Nwabor. 2022. Food Preservation and Safety of Natural Products. Food Preservation and Safety of Natural Products 163 174 .
Janice Mayne, Xu Zhang, James Butcher, Krystal Walker, Zhibin Ning, Ewelina Wójcik, Jarosław Dastych, Alain Stintzi & Daniel Figeys. (2021) Examining the Effects of an Anti-Salmonella Bacteriophage Preparation, BAFASAL®, on Ex-Vivo Human Gut Microbiome Composition and Function Using a Multi-Omics Approach. Viruses 13:9, pages 1734.
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Abdallah S. Abdelsattar, Anan Safwat, Rana Nofal, Amera Elsayed, Salsabil Makky & Ayman El-Shibiny. (2021) Isolation and Characterization of Bacteriophage ZCSE6 against Salmonella spp.: Phage Application in Milk. Biologics 1:2, pages 164-176.
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Abdallah Abdelsattar, Alyaa Dawooud, Nouran Rezk, Salsabil Makky, Anan Safwat, Philip Richards & Ayman El-Shibiny. (2021) How to Train Your Phage: The Recent Efforts in Phage Training. Biologics 1:2, pages 70-88.
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Abrar Senhaji-Kacha, Jaime Esteban & Meritxell Garcia-Quintanilla. (2021) Considerations for Phage Therapy Against Mycobacterium abscessus. Frontiers in Microbiology 11.
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Robert J. Atterbury & Paul A. Barrow. 2021. Bacteriophages. Bacteriophages 953 987 .
Eugene RosenbergEugene Rosenberg. 2021. Microbiomes. Microbiomes 353 412 .
Jiawei Ji, Qian Liu, Rui Wang, Tingting Luo, Xiaokui Guo, Mengsha Xu, Qian Yin, Xuetong Wang, Min Zhou, Min Li & Ping He. (2020) Identification of a novel phage targeting methicillin-resistant Staphylococcus aureus In vitro and In vivo. Microbial Pathogenesis 149, pages 104317.
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Diana P Pires, Ana Rita Costa, Graça Pinto, Luciana Meneses & Joana Azeredo. (2020) Current challenges and future opportunities of phage therapy. FEMS Microbiology Reviews 44:6, pages 684-700.
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Alex Echeverría-Vega, Pablo Morales-Vicencio, Camila Saez-Saavedra, María Alejandra Alvarez, Felipe Gordillo, Rodrigo Del-Valle, Ma. Eugenia Solís & Rubén Araya. (2020) Characterization of the Bacteriophage vB_VorS-PVo5 Infection on Vibrio ordalii: A Model for Phage-Bacteria Adsorption in Aquatic Environments. Frontiers in Microbiology 11.
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Tuba SAKİN ŞAHİN, Nida URGANCI & Zeliha YILDIRIM. (2020) LYTIC BACTERIOPHAGES EFFECTIVE AGAINST ESCHERICHIA COLI O157:H7, A FOODBORNE PATHOGENGIDA KAYNAKLI PATOJEN ESCHERICHIA COLI O157:H7’YE KARŞI ETKİLİ BAKTERİYOFAJLAR. Gıda 45:4, pages 635-645.
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Justyna D. Kowalska, Joanna Kazimierczak, Patrycja M. Sowińska, Ewelina A. Wójcik, Andrzej K. Siwicki & Jarosław Dastych. (2020) Growing Trend of Fighting Infections in Aquaculture Environment—Opportunities and Challenges of Phage Therapy. Antibiotics 9:6, pages 301.
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Leonid Ushanov, Besarion Lasareishvili, Irakli Janashia & Andreas E. Zautner. (2020) Application of Campylobacter jejuni Phages: Challenges and Perspectives. Animals 10:2, pages 279.
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João Sabino, Robert P. Hirten & Jean‐Frederic Colombel. (2019) Review article: bacteriophages in gastroenterology—from biology to clinical applications. Alimentary Pharmacology & Therapeutics 51:1, pages 53-63.
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Ayman El-Shibiny & Alyaa Dawoud. 2020. Biocommunication of Phages. Biocommunication of Phages 463 484 .
Ersilia V. Fiscarelli, Martina Rossitto & Paola Rosati. 2020. Biocommunication of Phages. Biocommunication of Phages 403 461 .
Carlos Angulo, Abraham Loera‐Muro, Edgar Trujillo & Antonio Luna‐González. (2018) Control of AHPND by phages: a promising biotechnological approach. Reviews in Aquaculture 11:4, pages 989-1004.
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Moustafa Zahran & Amal H. Marei. (2019) Innovative natural polymer metal nanocomposites and their antimicrobial activity. International Journal of Biological Macromolecules 136, pages 586-596.
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Ganeshan & Hosseinidoust. (2019) Phage Therapy with a focus on the Human Microbiota. Antibiotics 8:3, pages 131.
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Kyung Hyun Lee, Ji-Soo Lee, Eun Suh Kim & Hyeon Gyu Lee. (2019) Preparation, characterization, and food application of rosemary extract-loaded antimicrobial nanoparticle dispersions. LWT 101, pages 138-144.
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Mohammad Naghizadeh, Mohammad Amir Karimi Torshizi, Shaban Rahimi & Tina Sørensen Dalgaard. (2019) Synergistic effect of phage therapy using a cocktail rather than a single phage in the control of severe colibacillosis in quails. Poultry Science 98:2, pages 653-663.
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Muhsin Jamal, Sayed M. A. U. S. Bukhari, Saadia Andleeb, Muhammad Ali, Sana Raza, Muhammad A. Nawaz, Tahir Hussain, Sadeeq u. Rahman & Syed S. A. Shah. (2018) Bacteriophages: an overview of the control strategies against multiple bacterial infections in different fields. Journal of Basic Microbiology 59:2, pages 123-133.
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Marzena Połaska & Barbara Sokołowska. (2019) Bacteriophages—a new hope or a huge problem in the food industry. AIMS Microbiology 5:4, pages 324-346.
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Robert J. Atterbury & Paul A. Barrow. 2019. Bacteriophages. Bacteriophages 1 36 .
Antony T. Vincent, Valérie E. Paquet, Sylvain Moineau & Steve J. Charette. 2019. Microbial Communities in Aquaculture Ecosystems. Microbial Communities in Aquaculture Ecosystems 51 68 .
Taskeen Raza, Saadia Andleeb, Sidra Rahmat Ullah, Muhsin Jamal, Khalid Mehmood & Muhammad Ali. (2018) Isolation and Characterization of a Phage to Control Vancomycin Resistant Enterococcus faecium. Open Life Sciences 13:1, pages 553-560.
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Rachel Yoon Kyung Chang, Martin Wallin, Yu Lin, Sharon Sui Yee Leung, Hui Wang, Sandra Morales & Hak-Kim Chan. (2018) Phage therapy for respiratory infections. Advanced Drug Delivery Reviews 133, pages 76-86.
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Martina Rossitto, Ersilia V. Fiscarelli & Paola Rosati. (2018) Challenges and Promises for Planning Future Clinical Research Into Bacteriophage Therapy Against Pseudomonas aeruginosa in Cystic Fibrosis. An Argumentative Review. Frontiers in Microbiology 9.
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Guimin Zhang, Yin Zhao, Sathish Paramasivan, Katharina Richter, Sandra Morales, Peter-John Wormald & Sarah Vreugde. (2018) Bacteriophage effectively kills multidrug resistant Staphylococcus aureus clinical isolates from chronic rhinosinusitis patients . International Forum of Allergy & Rhinology 8:3, pages 406-414.
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Stephen T. Abedon. 2018. Bugs as Drugs. Bugs as Drugs 417 451 .
Yunfen Hua, Tingting Luo, Yiqi Yang, Dong Dong, Rui Wang, Yanjun Wang, Mengsha Xu, Xiaokui Guo, Fupin Hu & Ping He. (2018) Phage Therapy as a Promising New Treatment for Lung Infection Caused by Carbapenem-Resistant Acinetobacter baumannii in Mice. Frontiers in Microbiology 8.
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Stephen T. Abedon. (2017) Bacteriophage Clinical Use as Antibacterial “Drugs”: Utility and Precedent. Microbiology Spectrum 5:4.
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Hollie Hathaway, Scarlet Milo, J Mark Sutton & Toby A Jenkins. (2017) Recent advances in therapeutic delivery systems of bacteriophage and bacteriophage-encoded endolysins. Therapeutic Delivery 8:7, pages 543-556.
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Zhan Lu, Jianyi Zhang, Lizhou Xu, Yanbin Li, Siyu Chen, Zunzhong Ye & Jianping Wang. (2017) Design and Elementary Evaluation of a Highly-Automated Fluorescence-Based Instrument System for On-Site Detection of Food-Borne Pathogens. Sensors 17:3, pages 442.
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Stephen T. Abedon. (2017) Active bacteriophage biocontrol and therapy on sub-millimeter scales towards removal of unwanted bacteria from foods and microbiomes. AIMS Microbiology 3:3, pages 649-688.
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Alex Echeverría-Vega, Pablo Morales-Vicencio, Camila Saez-Saavedra, Janja Ceh & Rubén Araya. (2016) The complete genome sequence and analysis of vB_VorS-PVo5, a Vibrio phage infectious to the pathogenic bacterium Vibrio ordalii ATCC-33509. Standards in Genomic Sciences 11:1.
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Hui Zhang, Lu Li, Zhe Zhao, Daxin Peng & Xiaohui Zhou. (2016) Polar flagella rotation in Vibrio parahaemolyticus confers resistance to bacteriophage infection. Scientific Reports 6:1.
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Jaewoo Bai, You-Tae Kim, Sangryeol Ryu & Ju-Hoon Lee. (2016) Biocontrol and Rapid Detection of Food-Borne Pathogens Using Bacteriophages and Endolysins. Frontiers in Microbiology 7.
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