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Drug Profile

Posaconazole: clinical pharmacology and potential for management of fungal infections

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Pages 467-487 | Published online: 10 Jan 2014

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Qin Ding, Shuqi Huang, Zexu Sun, Kaifeng Chen, Xin Li & Qi Pei. (2022) A Review of Population Pharmacokinetic Models of Posaconazole. Drug Design, Development and Therapy 16, pages 3691-3709.
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Ganesh Chandra Sahoo, Md. Yousuf Ansari, Manas Ranjan Dikhit, M. Kannan, Sindhuprava Rana & Pradeep Das. (2014) Structure prediction of gBP21 protein of L. donovani and its molecular interaction. Journal of Biomolecular Structure and Dynamics 32:5, pages 709-729.
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Maged Muhammed, Herman Carneiro, Jeffrey Coleman & Eleftherios Mylonakis. (2011) The challenge of managing fusariosis. Virulence 2:2, pages 91-96.
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Rungmei S. K. Marak, Richa Misra, M. S. Ansari, Ajai Dixit, Poornima, K. N. Prasad & T. N. Dhole. (2010) Successful medical management of renal zygomycosis: a summary of two cases and a review of the Indian literature. Medical Mycology 48:8, pages 1088-1095.
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Winter J Smith, Richard H Drew & John R Perfect. (2009) Posaconazole’s impact on prophylaxis and treatment of invasive fungal infections: an update. Expert Review of Anti-infective Therapy 7:2, pages 165-181.
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Allen Moton, Lei Ma, Gopal Krishna, Monika Martinho, Michael Seiberling & James McLeod. (2009) Effects of oral posaconazole on the pharmacokinetics of sirolimus. Current Medical Research and Opinion 25:3, pages 701-707.
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Stefan Langner, Philipp B Staber & Peter Neumeister. (2008) Posaconazole in the management of refractory invasive fungal infections. Therapeutics and Clinical Risk Management 4:4, pages 747-758.
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Christine C Chiou, Thomas J Walsh & Andreas H Groll. (2007) Clinical pharmacology of antifungal agents in pediatric patients. Expert Opinion on Pharmacotherapy 8:15, pages 2465-2489.
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Douglas S Kwon & Eleftherios Mylonakis. (2007) Posaconazole: a new broad-spectrum antifungal agent. Expert Opinion on Pharmacotherapy 8:8, pages 1167-1178.
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Andreas H. Groll, Katharina Körholz, Malcolm Holterhus & Thomas Lehrnbecher. (2023) New and emerging options for management of invasive fungal diseases in paediatric patients. Mycoses 67:1.
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Sanjeevani Deshkar, Purva Yeole, Jayashri Mahore, Ankita Shinde & Prabhanjan Giram. (2023) Polyelectrolyte-Complex-Based Hydrogel Inserts for Vaginal Delivery of Posaconazole and Probiotics. Gels 9:11, pages 851.
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Yehia Elgammal, Ehab A Salama & Mohamed N Seleem. (2023) Saquinavir potentiates itraconazole’s antifungal activity against multidrug-resistant Candida auris in vitro and in vivo . Medical Mycology 61:9.
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Michail Lykouras, Malvina Orkoula & Christos Kontoyannis. (2022) Formation and Characterisation of Posaconazole Hydrate Form. Pharmaceuticals 16:1, pages 65.
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A. V. Veselov & N. N. Klimko. (2022) Intravenous posaconazole: key features of clinical pharmacology and practical applications. Oncohematology 17:2, pages 121-133.
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Jingxiang Zhang, Liping Li, Quanzhen Lv, Lan Yan, Yan Wang & Yuanying Jiang. (2019) The Fungal CYP51s: Their Functions, Structures, Related Drug Resistance, and Inhibitors. Frontiers in Microbiology 10.
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Lijun Yang, Min Yang, Siying Li & Zhongxi Zhao. (2018) S-allylmercaptocysteine attenuates posaconazole-induced adverse effects in mice through antioxidation and anti-inflammation. International Immunopharmacology 58, pages 9-14.
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Mar Tormo, Ariadna Pérez-Martínez, Marisa Calabuig, Juan Carlos Hernández-Boluda, Paula Amat, David Navarro & Carlos Solano. (2018) Primary prophylaxis of invasive fungal infections with posaconazole or itraconazole in patients with acute myeloid leukaemia or high-risk myelodysplastic syndromes undergoing intensive cytotoxic chemotherapy: A real-world comparison. Mycoses 61:3, pages 206-212.
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Whitley M. Yi, Kelly E. Schoeppler, Jaclyn Jaeger, Scott W. Mueller, Robert MacLaren, Douglas N. Fish & Tyree H. Kiser. (2017) Voriconazole and posaconazole therapeutic drug monitoring: a retrospective study. Annals of Clinical Microbiology and Antimicrobials 16:1.
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E. Cendejas-Bueno, A. Forastiero, I. Ruiz, E. Mellado, J. Gavaldà & A. Gomez-Lopez. (2017) Blood and tissue distribution of posaconazole in a rat model of invasive pulmonary aspergillosis. Diagnostic Microbiology and Infectious Disease 87:2, pages 112-117.
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