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Perspective

Vancomycin: does it still have a role as an antistaphylococcal agent?

Pages 393-401 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Cameron J Phillips, Nicholas A Wells, Marianne Martinello, Simon Smith, Richard J Woodman & David L Gordon. (2016) Optimizing the detection of methicillin-resistant Staphylococcus aureus with elevated vancomycin minimum inhibitory concentrations within the susceptible range. Infection and Drug Resistance 9, pages 87-92.
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Sharath S Hegde & James W Janc. (2014) Efficacy of telavancin, a lipoglycopeptide antibiotic, in experimental models of Gram-positive infection. Expert Review of Anti-infective Therapy 12:12, pages 1463-1475.
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J. Floris S. Logman, Jennifer Stephens, Bart Heeg, Seema Haider, Joseph Cappelleri, Dilip Nathwani, Alan Tice & Ben A. van Hout. (2010) Comparative effectiveness of antibiotics for the treatment of MRSA complicated skin and soft tissue infections. Current Medical Research and Opinion 26:7, pages 1565-1578.
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Patricia L Schirmer & Stanley C Deresinski. (2009) Ceftobiprole: a new cephalosporin for the treatment of skin and skin structure infections. Expert Review of Anti-infective Therapy 7:7, pages 777-791.
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Georg Schitter & Tanja M Wrodnigg. (2009) Update on carbohydrate-containing antibacterial agents. Expert Opinion on Drug Discovery 4:3, pages 315-356.
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William J Peppard, Carolyn J Johnston & Angela M Urmanski. (2008) Pharmacologic options for CNS infections caused by resistant Gram-positive organisms. Expert Review of Anti-infective Therapy 6:1, pages 83-99.
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Nawras Osman, Mahir Mohammed, Calvin A. Omolo, Usri H. Ibrahim, Mohammed A. Gafar, Sanjeev Rambharose, Nikita Devnarain, Lucy W. Kiruri, Joshua Nwabuife & Thirumala Govender. (2023) Hyaluronidase inhibitor surface-modified niosomes: An efficient strategy for antibacterial and anti-biofilm drug delivery. Materialia 30, pages 101826.
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Kyoung-Ho Song. (2022) Antibiotics for multidrug-resistant gram-positive bacteria. Journal of the Korean Medical Association 65:8, pages 478-489.
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Subhasis Mahari, Deepshikha Shahdeo, Ivneet Banga, Samraggi Choudhury & Sonu Gandhi. 2022. Peptide and Peptidomimetic Therapeutics. Peptide and Peptidomimetic Therapeutics 657 688 .
Donald J. AbrahamSebastian A. Testero, Leticia I. Llarrull, Jed F. Fisher & Shahriar Mobashery. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 188 .
Bonggoo Park & George Y. Liu. (2021) Immune-Based Anti-Staphylococcal Therapeutic Approaches. Microorganisms 9:2, pages 328.
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Sarah C. J. Jorgensen, Kyle P. Murray, Abdalhamid M. Lagnf, Sarah Melvin, Sahil Bhatia, Muhammad-Daniayl Shamim, Jordan R. Smith, Karrine D. Brade, Samuel P. Simon, Jerod Nagel, Karen S. Williams, Jessica K. Ortwine, Michael P. Veve, James Truong, David B. Huang, Susan L. Davis & Michael J. Rybak. (2020) A Multicenter Evaluation of Vancomycin-Associated Acute Kidney Injury in Hospitalized Patients with Acute Bacterial Skin and Skin Structure Infections. Infectious Diseases and Therapy 9:1, pages 89-106.
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T. D. Trinh, S. C. J. Jorgensen, E. J. Zasowski, K. C. Claeys, A. M. Lagnf, S. J. Estrada, D. J. Delaportes, V. Huang, K. P. Klinker, K. S. Kaye, S. L. Davis & M. J. Rybak. (2019) Multicenter Study of the Real-World Use of Ceftaroline versus Vancomycin for Acute Bacterial Skin and Skin Structure Infections. Antimicrobial Agents and Chemotherapy 63:11.
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T.A.S. Aguirre, D. Teijeiro-Osorio, M. Rosa, I.S. Coulter, M.J. Alonso & D.J. Brayden. (2016) Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials. Advanced Drug Delivery Reviews 106, pages 223-241.
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Joshua S. Davis, Archana Sud, Matthew V. N. O'Sullivan, James O. Robinson, Patricia E. Ferguson, Hong Foo, Sebastiaan J. van Hal, Anna P. Ralph, Benjamin P. Howden, Paula M. Binks, Adrienne Kirby & Steven Y. C. Tong. (2016) Combination of Vancomycin and β-Lactam Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: A Pilot Multicenter Randomized Controlled Trial . Clinical Infectious Diseases 62:2, pages 173-180.
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M. J. DiNubile. (2015) Trials and Tribulations of Noninferiority: Caveat Emptor. Clinical Infectious Diseases 60:8, pages 1290-1291.
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Stan Deresinski. (2012) Methicillin-Resistant Staphylococcus aureus and Vancomycin: Minimum Inhibitory Concentration Matters. Clinical Infectious Diseases 54:6, pages 772-774.
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Jeffrey Fernandez, Darren Abbanat, Wenchi Shang, Wenping He, Karen Amsler, James Hastings, Anne Marie Queenan, John L. Melton, Alfred M. Barron, Robert K. Flamm & A. Simon Lynch. (2012) Synergistic Activity of Ceftobiprole and Vancomycin in a Rat Model of Infective Endocarditis Caused by Methicillin-Resistant and Glycopeptide-Intermediate Staphylococcus aureus. Antimicrobial Agents and Chemotherapy 56:3, pages 1476-1484.
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Sharath S. Hegde, Olanrewaju O. Okusanya, Robert Skinner, Jeng-Pyng Shaw, Glenmar Obedencio, Paul G. Ambrose, Johanne Blais & Sujata M. Bhavnani. (2012) Pharmacodynamics of TD-1792, a Novel Glycopeptide-Cephalosporin Heterodimer Antibiotic Used against Gram-Positive Bacteria, in a Neutropenic Murine Thigh Model. Antimicrobial Agents and Chemotherapy 56:3, pages 1578-1583.
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F. F. Arhin, A. Belley, A. Rafai Far, D. Lehoux, G. Moeck & T. R. ParrJr.Jr.. 2012. Antibiotic Discovery and Development. Antibiotic Discovery and Development 301 346 .
Youmna Abi-HaidarKalpana GuptaJudith StrymishSandra A. WilliamsKamal M.F. Itani. (2011) Factors Associated with Post-Operative Conversion to Methicillin-Resistant Staphylococcus Aureus Positivity or Infection in Initially MRSA-Negative Patients . Surgical Infections 12:6, pages 435-442.
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María Isabel Morosini & Rafael Cantón. (2010) Tolerancia y heterorresistencia en microorganismos grampositivos. Medicina Clínica 135, pages 16-22.
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Donald J. AbrahamSebastian A. Testero, Jed F. Fisher & Shahriar Mobashery. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 257 402 .
Omar Vesga, Maria Agudelo, Beatriz E. Salazar, Carlos A. Rodriguez & Andres F. Zuluaga. (2010) Generic Vancomycin Products Fail In Vivo despite Being Pharmaceutical Equivalents of the Innovator . Antimicrobial Agents and Chemotherapy 54:8, pages 3271-3279.
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Brian C. Diener. (2010) Avoidance of Dominant Hand Amputation in a Patient with Uncontrolled Diabetes. Advances in Skin & Wound Care 23:5, pages 219-222.
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F. Taieb, A. Le Monnier, E. Bille, F. Lanternier, F. Mechai, F. Ribadeau-Dumas, E. Maenulein, C. Forge, O. Corriol, X. Nassif, O. Lortholary & J.-R. Zahar. (2010) Optimisation de la prescription de la vancomycine : étude prospective observationnelle dans un centre hospitalo-universitaire parisien. Médecine et Maladies Infectieuses 40:5, pages 273-278.
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S. M. Breathnach, C. H. Smith, R. J. G. Chalmers & R. J. Hay. 2010. Rook's Textbook of Dermatology. Rook's Textbook of Dermatology 1 53 .
I. Uçkay, D. Teterycz, T. Ferry, S. Harbarth, A. Lübbeke, S. Emonet, M. Chilcott, P. Hoffmeyer & L. Bernard. (2009) Poor utility of MRSA screening to predict staphylococcal species in orthopaedic implant infections. Journal of Hospital Infection 73:1, pages 89-91.
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Jochanan E. Naschitz, Andrey Gagarin & Ruth Gropper Schor. (2008) Spurious toxic vancomycin levels. European Journal of Internal Medicine 19:6, pages e36-e37.
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Leticia Vale Scribel da Silva, Alexandre Prehn Zavascki, Monica Vinhas de Souza & Aline Marcadenti. (2008) Caution when reconsidering empiric antimicrobial therapy for methicillin-resistant Staphylococcus aureus skin and soft-tissue infections. The American Journal of Surgery 196:4, pages 618-619.
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Stanley C. Deresinski. (2008) Ceftobiprole: breaking therapeutic dogmas of the β-lactam class. Diagnostic Microbiology and Infectious Disease 61:1, pages 82-85.
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James S LewisIIII & Michael W Ellis. (2008) Approaches to serious methicillin-resistant Staphylococcus aureus infections with decreased susceptibility to vancomycin: clinical significance and options for management. Current Opinion in Internal Medicine 7:1, pages 65-70.
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C. von Eiff & F. Kipp. (2007) Kolonisation und Infektion durch methicillinresistente Staphylococcus-aureus-StämmeColonisation and infection by methicillin-resistant Staphylococcus aureus strains. Trauma und Berufskrankheit 9:S3, pages S274-S277.
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Nawras Osman, Calvin A. Omolo, Nikita Devnarain, Chunderika Mocktar, Sanjeev Rambharose, Usri H. Ibrahim, Victoria O. Fasiku & Thirumala Govender. (2022) Niosomes Modified with a Novel pH-Responsive Coating (mPEG-OA) Enhance the Antibacterial and Anti-Biofilm Activity of Vancomycin Against Methicillin-Resistant <i>Staphylococcus aureus</i>. SSRN Electronic Journal.
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