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Review

Tularemia: current diagnosis and treatment options

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Pages 231-240 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Raju Sunagar, Sudeep Kumar, Brian J Franz & Edmund J Gosselin. (2016) Tularemia vaccine development: paralysis or progress?. Vaccine: Development and Therapy 6, pages 9-23.
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Max Maurin. (2015) Francisella tularensis as a potential agent of bioterrorism?. Expert Review of Anti-infective Therapy 13:2, pages 141-144.
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Yan-Yan Zhang, Yong Liu, Shahila Mehboob, Jin-Hua Song, Teuta Boci, Michael E. Johnson, Arun K. Ghosh & Hyunyoung Jeong. (2014) Metabolism-directed structure optimization of benzimidazole-based Francisella tularensis enoyl-reductase (FabI) inhibitors. Xenobiotica 44:5, pages 404-416.
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Tuba Celik, Mustafa Kosker & Elif Betul Turkoglu. (2013) Unilateral Acute Dacryocystitis Associated with Oculoglandular Tularemia: A Case Report. Seminars in Ophthalmology 28:2, pages 91-93.
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Articles from other publishers (82)

Rebin Rafaat MohammedAhmad EnferadiKarzan R. SidiqSaeedeh SaraniPeyman KhademiAmin JaydariAvin Kawa Ahmed. (2023) Molecular Detection of Francisella tularensis Isolated from Ticks of Livestock in Kurdistan Region, Iraq . Vector-Borne and Zoonotic Diseases.
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Léa Ponderand, Thomas Guimard, Estibaliz Lazaro, Henry Dupuy, Olivia Peuchant, Nathalie Roch, Philippe Deroche, Tristan Ferry, Max Maurin, Aurélie Hennebique, Sandrine Boisset, Isabelle Pelloux & Yvan Caspar. (2023) Case Studies and Literature Review of Francisella tularensis –Related Prosthetic Joint Infection . Emerging Infectious Diseases 29:6.
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Phillip R. Pittman, Gunnstein Norheim, Benjamin Pierson & Fernando B. Guerena. 2023. Plotkin's Vaccines. Plotkin's Vaccines 172 190.e9 .
Nadezhda A. Byzova, Anatoly V. Zherdev, Alexey A. Gorbatov, Anton G. Shevyakov, Sergey F. Biketov & Boris B. Dzantiev. (2022) Rapid Detection of Lipopolysaccharide and Whole Cells of Francisella tularensis Based on Agglutination of Antibody-Coated Gold Nanoparticles and Colorimetric Registration. Micromachines 13:12, pages 2194.
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Sahar Sabour, Taher Azimi, Ahmad Nasser, Nahal Hadi, Amin Mohsenzadeh & Aref Shariati. (2022) A global overview of the most important zoonotic bacteria pathogens transmitted from Rattus norvegicus to humans in urban environments. Infectious Medicine 1:3, pages 192-207.
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Emre ARSLANBAŞ & Emine BAYDAN. (2022) EGZOTİK (YABANİ) HAYVANLARDAN KAYNAKLI ZOONOZLAR VE SAĞALTIMIEXOTIC (WILD) ANIMALS ORIGINATED ZOONOSES AND THEIR TREATMENT. Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni 13:2, pages 78-89.
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Göran Ramin Boeckel, Jan Basri Adiprasito, Neele Judith Froböse, Frieder Schaumburg, Richard Vollenberg & Phil-Robin Tepasse. (2022) Tularemia Presenting Solely with Cervical Lymphadenopathy and Fever. Diagnostics 12:8, pages 2000.
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Kevin D. Mlynek, Christopher T. Lopez, David P. Fetterer, Janice A. Williams & Joel A. Bozue. (2022) Phase Variation of LPS and Capsule Is Responsible for Stochastic Biofilm Formation in Francisella tularensis. Frontiers in Cellular and Infection Microbiology 11.
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Maja Prah, Ana Kenk & Jana Rejc Marko. (2022) Skin involvement in Francisella tularensis infection: a case report of two clinical cases. Acta Dermatovenerologica Alpina Pannonica et Adriatica 31:2.
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Pierre H. Boyer, Antoine Grillon, Benoît Jaulhac, Aurélie Velay, Frédéric Schramm & Emilie Talagrand-Reboul. 2022. Lyme Borreliosis. Lyme Borreliosis 193 234 .
Olivier Bahuaud, Cécile Le Brun & Adrien Lemaignen. (2021) Host Immunity and Francisella tularensis: A Review of Tularemia in Immunocompromised Patients. Microorganisms 9:12, pages 2539.
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Veronika Merold, Kim Silberreis & Kilian Stoecker. (2021) Development and Validation of Ribosomal RNA-Targeted Reverse Transcription Real-Time PCR Assays for the Sensitive and Rapid Diagnostics of High Consequence Pathogens. Frontiers in Microbiology 12.
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Emily E. Hannah, Sujata G. Pandit, Derrick Hau, Haley L. DeMers, Kayleigh Robichaux, Teerapat Nualnoi, Anjana Dissanayaka, Jose Arias-Umana, Heather R. Green, Peter Thorkildson, Kathryn J. Pflughoeft, Marcellene A. Gates-Hollingsworth, Yasemin Ozsurekci & David P. AuCoin. (2021) Development of Immunoassays for Detection of Francisella tularensis Lipopolysaccharide in Tularemia Patient Samples. Pathogens 10:8, pages 924.
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Kay B. Barnes, Mark I. Richards, Thomas R. Laws, Alejandro Núñez, Joanne E. Thwaite, Christine Bentley & Sarah V. Harding. (2021) Finafloxacin Is an Effective Treatment for Inhalational Tularemia and Plague in Mouse Models of Infection. Antimicrobial Agents and Chemotherapy 65:6.
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Caleb R. S. McEntire, Kun-Wei Song, Robert P. McInnis, John Y. Rhee, Michael Young, Erika Williams, Leah L. Wibecan, Neal Nolan, Amanda M. Nagy, Jeffrey Gluckstein, Shibani S. Mukerji & Farrah J. Mateen. (2021) Neurologic Manifestations of the World Health Organization's List of Pandemic and Epidemic Diseases. Frontiers in Neurology 12.
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N. Tissot, S. Noureddine, M. Guion-Dusserre & T. Soumagne. (2021) Bilan d’adénopathies médiastinales : ne pas méconnaître une tularémie !. Revue des Maladies Respiratoires 38:2, pages 204-209.
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Sanjana Vijay Nemade & Kiran Jaywant ShindeSanjana Vijay Nemade & Kiran Jaywant Shinde. 2021. Granulomatous diseases in Otorhinolaryngology, Head and Neck. Granulomatous diseases in Otorhinolaryngology, Head and Neck 95 100 .
Zakaria Abdellahoum, Max Maurin & Idir Bitam. (2020) Tularemia as a Mosquito-Borne Disease. Microorganisms 9:1, pages 26.
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Vivien Sutera, Aurélie Hennebique, Fabrice Lopez, Nicolas Fernandez, Dominique Schneider & Max Maurin. (2020) Genomic trajectories to fluoroquinolone resistance in Francisella tularensis subsp. holarctica live vaccine strain. International Journal of Antimicrobial Agents 56:6, pages 106153.
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Fabrice V. Biot, Beth A. Bachert, Kevin D. Mlynek, Ronald G. Toothman, Galina I. Koroleva, Sean P. Lovett, Christopher P. Klimko, Gustavo F. Palacios, Christopher K. Cote, Jason T. Ladner & Joel A. Bozue. (2020) Evolution of Antibiotic Resistance in Surrogates of Francisella tularensis (LVS and Francisella novicida): Effects on Biofilm Formation and Fitness. Frontiers in Microbiology 11.
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Max Maurin. (2020) Francisella tularensis, Tularemia and Serological Diagnosis. Frontiers in Cellular and Infection Microbiology 10.
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Sofiane Regoui, Aurélie Hennebique, Thomas Girard, Sandrine Boisset, Yvan Caspar & Max Maurin. (2020) Optimized MALDI TOF Mass Spectrometry Identification of Francisella tularensis Subsp. holarctica. Microorganisms 8:8, pages 1143.
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Max Maurin. 2020. Hunter's Tropical Medicine and Emerging Infectious Diseases. Hunter's Tropical Medicine and Emerging Infectious Diseases 630 635 .
Jayant Patwa & S.J.S. Flora. 2020. Handbook on Biological Warfare Preparedness. Handbook on Biological Warfare Preparedness 151 172 .
Ryan C. Maves & Catherine M. Berjohn. 2020. Highly Infectious Diseases in Critical Care. Highly Infectious Diseases in Critical Care 97 118 .
Saber Esmaeili, Ahmad Ghasemi, Razi Naserifar, Ali Jalilian, Leila Molaeipoor, Max Maurin & Ehsan Mostafavi. (2019) Epidemiological survey of tularemia in Ilam Province, west of Iran. BMC Infectious Diseases 19:1.
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Todd M. Kijek, Sherry Mou, Beth A. Bachert, Kathleen A. Kuehl, Janice A. Williams, Sharon P. Daye, Patricia L. Worsham & Joel A. Bozue. (2019) The D-alanyl-d-alanine carboxypeptidase enzyme is essential for virulence in the Schu S4 strain of Francisella tularensis and a dacD mutant is able to provide protection against a pneumonic challenge. Microbial Pathogenesis 137, pages 103742.
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Kay B. Barnes, Karleigh A. Hamblin, Mark I. Richards, Thomas R. Laws, Andreas Vente, Helen S. Atkins & Sarah V. Harding. (2019) The Fluoroquinolone Finafloxacin Protects BALB/c Mice Against an Intranasal Infection With Francisella tularensis Strain SchuS4. Frontiers in Microbiology 10.
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Christina A. Nelson, Christian Murua, Jefferson M. Jones, Kelli Mohler, Ying Zhang, Landon Wiggins, Natalie A. Kwit, Laurel Respicio-Kingry, Luke C. Kingry, Jeannine M. Petersen, Jennifer Brown, Saima Aslam, Melissa Krafft, Shadaba Asad, Hikmat N. Dagher, John Ham, Luis H. Medina-Garcia, Kevin Burns, Walter E. Kelley, Alison F. Hinckley, Pallavi Annambhotla, Karen Carifo, Anthony Gonzalez, Elizabeth Helsel, Joseph Iser, Michael Johnson, Curtis L. Fritz & Sridhar V. Basavaraju. (2019) Francisella tularensis Transmission by Solid Organ Transplantation, 20171 . Emerging Infectious Diseases 25:4, pages 767-775.
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J. Heichel, E. Luci, H.-G. Struck, U. Siebolts, C. Wickenhauser, S. Plontke, A. Viestenz & G. Götze. (2018) Sekundär erworbene Tränenwegsstenose und zervikale LymphadenopathieSecondary acquired lacrimal duct obstruction and cervical lymphadenopathy. HNO 66:11, pages 847-850.
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L. A. Dykman, O. A. Volokh, E. M. Kuznetsova & A. K. Nikiforov. (2019) Immunogenicity of Conjugates of Protective Antigen Complexes of Tularemia Microbe with Gold Nanoparticles. Nanotechnologies in Russia 13:7-8, pages 384-392.
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Jinhong Ren, Tina L. Mistry, Pin-Chih Su, Shahila Mehboob, Robel Demissie, Leslie Wo-Mei Fung, Arun K. Ghosh & Michael E. Johnson. (2018) Determination of absolute configuration and binding efficacy of benzimidazole-based FabI inhibitors through the support of electronic circular dichroism and MM-GBSA techniques. Bioorganic & Medicinal Chemistry Letters 28:11, pages 2074-2079.
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Alisa W. Serio, Tiffany Keepers, Logan Andrews & Kevin M. Krause. (2018) Aminoglycoside Revival: Review of a Historically Important Class of Antimicrobials Undergoing Rejuvenation. EcoSal Plus 8:1.
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Hadjila Yanes, Aurélie Hennebique, Isabelle Pelloux, Sandrine Boisset, Dominique J. Bicout, Yvan Caspar & Max Maurin. (2018) Evaluation of In-House and Commercial Serological Tests for Diagnosis of Human Tularemia. Journal of Clinical Microbiology 56:1.
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Phillip R. Pittman & Stanley A. Plotkin. 2018. Plotkin's Vaccines. Plotkin's Vaccines 149 160.e7 .
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V. Sutera, G. Hoarau, P. Renesto, Y. Caspar & M. Maurin. (2017) In vitro and in vivo evaluation of fluoroquinolone resistance associated with DNA gyrase mutations in Francisella tularensis , including in tularaemia patients with treatment failure. International Journal of Antimicrobial Agents 50:3, pages 377-383.
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Taylor Chance, Jennifer Chua, Ronald G. Toothman, Jason T. Ladner, Jonathan E. Nuss, Jo Lynne Raymond, Fabrice V. Biot, Samandra Demons, Lynda Miller, Stephanie Halasohoris, Sherry Mou, Galina Koroleva, Sean Lovett, Gustavo Palacios, Nicholas J. Vietri, Patricia L. Worsham, Christopher K. Cote, Todd M. Kijek & Joel A. Bozue. (2017) A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia. PLOS ONE 12:3, pages e0174106.
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Herbert Tomaso & Helmut Hotzel. (2017) Tularemia from a One Health Perspective. Current Clinical Microbiology Reports 4:1, pages 36-42.
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