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Quantitative targeted proteomics for understanding the blood–brain barrier: towards pharmacoproteomics

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Yannis Karamanos & Gwënaël Pottiez. (2016) Proteomics and the blood–brain barrier: how recent findings help drug development. Expert Review of Proteomics 13:3, pages 251-258.
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Danica B Stanimirovic, Mahmud Bani-Yaghoub, Martin Perkins & Arsalan S Haqqani. (2015) Blood–brain barrier models: in vitro to in vivo translation in preclinical development of CNS-targeting biotherapeutics. Expert Opinion on Drug Discovery 10:2, pages 141-155.
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Articles from other publishers (31)

Shanshan Zhao, Qixue Bao, Guochen Ma, Yuqin Yao, Linshen Xie & Jingyuan Xiong. (2023) Benzo[b]fluoranthene (B[b]F) affects apoptosis, oxidative stress, mitochondrial membrane potential and expressions of blood-brain barrier markers in microvascular endothelial cells. Toxicology in Vitro 86, pages 105522.
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Maria Luz Alonso-Alonso, Ana Sampedro-Viana, Sabela Fernández-Rodicio, Marcos Bazarra-Barreiros, Alberto Ouro, Tomás Sobrino, Francisco Campos, José Castillo, Pablo Hervella & Ramón Iglesias-Rey. (2022) Need for a Paradigm Shift in the Treatment of Ischemic Stroke: The Blood-Brain Barrier. International Journal of Molecular Sciences 23:16, pages 9486.
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Matthew D. Harwood, Amin Rostami‐Hodjegan & Sibylle Neuhoff. 2022. Drug Transporters. Drug Transporters 475 496 .
Yoshiki Hashimoto, Kazuyoshi Michiba, Kazuya Maeda & Hiroyuki Kusuhara. (2022) Quantitative prediction of pharmacokinetic properties of drugs in humans: Recent advance in in vitro models to predict the impact of efflux transporters in the small intestine and blood–brain barrier. Journal of Pharmacological Sciences 148:1, pages 142-151.
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Stephanie A. Ihezie, Iny Elizebeth Mathew, Devin W. McBride, Ari Dienel, Spiros L. Blackburn & Peeyush Kumar Thankamani Pandit. (2021) Epigenetics in blood–brain barrier disruption. Fluids and Barriers of the CNS 18:1.
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Takeshi Masuda, Ayano Mori, Shingo Ito & Sumio Ohtsuki. (2021) Quantitative and targeted proteomics-based identification and validation of drug efficacy biomarkers. Drug Metabolism and Pharmacokinetics 36, pages 100361.
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Seigo Kimura & Hideyoshi Harashima. (2020) Current Status and Challenges Associated with CNS-Targeted Gene Delivery across the BBB. Pharmaceutics 12:12, pages 1216.
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Wooin Lee, Jeong-min Ha & Yuichi Sugiyama. (2020) Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion–transporting polypeptides. Journal of Biological Chemistry 295:50, pages 17349-17364.
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Eugene R Viscusi & Andrew R Viscusi. (2020) Blood–brain barrier: mechanisms governing permeability and interaction with peripherally acting μ-opioid receptor antagonists. Regional Anesthesia & Pain Medicine 45:9, pages 688-695.
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William M. Pardridge. (2020) The Isolated Brain Microvessel: A Versatile Experimental Model of the Blood-Brain Barrier. Frontiers in Physiology 11.
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Takeshi Masuda, Toshiki Hoshiyama, Tatsuki Uemura, Mio Hirayama-Kurogi, Seiryo Ogata, Arisu Furukawa, Pierre-Olivier Couraud, Tomomi Furihata, Shingo Ito & Sumio Ohtsuki. (2019) Large-Scale Quantitative Comparison of Plasma Transmembrane Proteins between Two Human Blood–Brain Barrier Model Cell Lines, hCMEC/D3 and HBMEC/ciβ. Molecular Pharmaceutics 16:5, pages 2162-2171.
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Bhupesh Sharma, Kanishk Luhach & G.T. Kulkarni. 2019. Brain Targeted Drug Delivery System. Brain Targeted Drug Delivery System 53 101 .
Stephen B. Hladky & Margery A. Barrand. (2018) Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier. Fluids and Barriers of the CNS 15:1.
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Yamato Sano, Tadahaya Mizuno, Tatsuki Mochizuki, Yasuo Uchida, Mina Umetsu, Tetsuya Terasaki & Hiroyuki Kusuhara. (2018) Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier. Drug Metabolism and Disposition 46:11, pages 1767-1775.
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Hajar Al Feteisi, Zubida M. Al-Majdoub, Brahim Achour, Narciso Couto, Amin Rostami-Hodjegan & Jill Barber. (2018) Identification and quantification of blood-brain barrier transporters in isolated rat brain microvessels. Journal of Neurochemistry 146:6, pages 670-685.
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Hassan Pezeshgi Modarres, Mohsen Janmaleki, Mana Novin, John Saliba, Fatima El-Hajj, Mahdi RezayatiCharan, Amir Seyfoori, Hamid Sadabadi, Milène Vandal, Minh Dang Nguyen, Anwarul Hasan & Amir Sanati-Nezhad. (2018) In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain. Journal of Controlled Release 273, pages 108-130.
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Soo Jung Lee, Soonhyung Kwon, John R. Gatti, Ejona Korcari, Ty E. Gresser, Princess C. Felix, Simon G. Keep, Kevin C. Pasquale, Tongxu Bai, Sabrina A. Blanchett-Anderson, Nancy W. Wu, Charissa Obeng-Nyarko, Kossi M. Senagbe, Kathy C. Young, Snehaa Maripudi, Bharath C. Yalavarthi, Dajana Korcari, Andre Y. Liu, Benjamin C. Schaffler, Richard F. Keep & Michael M. Wang. (2017) Large-scale identification of human cerebrovascular proteins: Inter-tissue and intracerebral vascular protein diversity. PLOS ONE 12:11, pages e0188540.
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Imre Mäger, Axel H. Meyer, Jinghuan Li, Martin Lenter, Tobias Hildebrandt, German Leparc & Matthew J.A. Wood. (2017) Targeting blood-brain-barrier transcytosis – perspectives for drug delivery. Neuropharmacology 120, pages 4-7.
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Tuo Yang, Yang Sun, Zhengyu Lu, Rehana K. Leak & Feng Zhang. (2017) The impact of cerebrovascular aging on vascular cognitive impairment and dementia. Ageing Research Reviews 34, pages 15-29.
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Ozgun F. Duzenli & Ayşe Filiz Oner. 2017. Nanotechnology Methods for Neurological Diseases and Brain Tumors. Nanotechnology Methods for Neurological Diseases and Brain Tumors 15 34 .
D.G. Munoz & N. Weishaupt. 2017. The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders. The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders 119 139 .
Bianca M. Liederer, Xingrong Liu, Simon Wong & Daniel R. Mudra. 2017. Translating Molecules into Medicines. Translating Molecules into Medicines 165 230 .
Allison B. Chambliss & Daniel W. Chan. (2016) Precision medicine: from pharmacogenomics to pharmacoproteomics. Clinical Proteomics 13:1.
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Ravi K Sajja, Shafiqur Rahman & Luca Cucullo. (2015) Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress. Journal of Cerebral Blood Flow & Metabolism 36:3, pages 539-554.
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Géraldine Pottier, Solène Marie, Sébastien Goutal, Sylvain Auvity, Marie-Anne Peyronneau, Simon Stute, Raphaël Boisgard, Frédéric Dollé, Irène Buvat, Fabien Caillé & Nicolas Tournier. (2016) Imaging the Impact of the P-Glycoprotein (ABCB1) Function on the Brain Kinetics of Metoclopramide. Journal of Nuclear Medicine 57:2, pages 309-314.
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Agnes Basseville, Matthew D. Hall, Cindy H. Chau, Robert W. Robey, Michael Gottesman, William D. Figg & Susan E. Bates. 2016. ABC Transporters - 40 Years on. ABC Transporters - 40 Years on 195 226 .
Aki T. Heikkinen, Floriane Lignet, Paul Cutler & Neil Parrott. (2015) The role of quantitative ADME proteomics to support construction of physiologically based pharmacokinetic models for use in small molecule drug development. PROTEOMICS - Clinical Applications 9:7-8, pages 732-744.
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Bruno Stieger & Bo Gao. (2015) Drug Transporters in the Central Nervous System. Clinical Pharmacokinetics 54:3, pages 225-242.
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Andreas Reichel. 2015. Blood-Brain Barrier in Drug Discovery. Blood-Brain Barrier in Drug Discovery 5 41 .
Atticus H. Hainsworth, Asho T. Oommen & Leslie R. Bridges. (2015) Endothelial Cells and Human Cerebral Small Vessel Disease. Brain Pathology 25:1, pages 44-50.
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Yannis Karamanos, Fabien Gosselet, Marie-Pierre Dehouck & Roméo Cecchelli. (2014) Blood–Brain Barrier Proteomics: Towards the Understanding of Neurodegenerative Diseases. Archives of Medical Research 45:8, pages 730-737.
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