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Expert Review of Proteomics Volume 5, 2008 - Issue 2
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Review

α-synuclein and Parkinson’s disease: a proteomic view

Mauro Fasano Professor of Biochemistry, Department of Structural & Functional Biology, & Centre of Neuroscience, University of Insubria, Via Alberto da Giussano 12, 21052 Busto Arsizio, Italy. [email protected]
&
Leonardo Lopiano Professor of Neurology, Department of Neuroscience, University of Torino, Via Cherasco 15, 10126 Torino, Italy. [email protected]
Pages 239-248 | Published online: 09 Jan 2014

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Murat Kasap, Gurler Akpinar & Aylin Kanli. (2017) Proteomic studies associated with Parkinson’s disease. Expert Review of Proteomics 14:3, pages 193-209.
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Philip A Robinson. (2010) Understanding the molecular basis of Parkinson’s disease, identification of biomarkers and routes to therapy. Expert Review of Proteomics 7:4, pages 565-578.
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Garima Srivastava, Kavita Singh, Manindra Nath Tiwari & Mahendra Pratap Singh. (2010) Proteomics in Parkinson’s disease: current trends, translational snags and future possibilities. Expert Review of Proteomics 7:1, pages 127-139.
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Articles from other publishers (24)

Ritoban Mitra, Lavienraj Premraj & Tien K. Khoo. (2023) Neuromelanin: Its role in the pathogenesis of idiopathic Parkinson's disease and potential as a therapeutic target. Parkinsonism & Related Disorders 112, pages 105448.
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Gagan Raju & Nirmal Mazumder. 2022. Advances in Brain Imaging Techniques. Advances in Brain Imaging Techniques 23 38 .
Wenjie Li, Yuan Luo, Hongyu Xu, Qianqian Ma & Qi Yao. (2021) Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson’s disease in mice. Journal of International Medical Research 49:4, pages 030006052199847.
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M. Swaminathan, C. Fung, D.I. Finkelstein, J.C. Bornstein & J.P.P. Foong. (2019) α-Synuclein Regulates Development and Function of Cholinergic Enteric Neurons in the Mouse Colon. Neuroscience 423, pages 76-85.
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Ann Brinkmalm, Erik Portelius, Gunnar Brinkmalm, Josef Pannee, Rahil Dahlén, Johan Gobom, Kaj Blennow & Henrik Zetterberg. (2018) Fluid‐based proteomics targeted on pathophysiological processes and pathologies in neurodegenerative diseases. Journal of Neurochemistry 151:4, pages 417-434.
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Ramavati Pal, Jan Petter Larsen & Simon Geir Moller. 2015. Omic Studies of Neurodegenerative Disease: Part A. Omic Studies of Neurodegenerative Disease: Part A 25 58 .
L Zondler, L Miller-Fleming, M Repici, S Gonçalves, S Tenreiro, R Rosado-Ramos, C Betzer, K R Straatman, P H Jensen, F Giorgini & T F Outeiro. (2014) DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson’s disease. Cell Death & Disease 5:7, pages e1350-e1350.
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Ramavati Pal, Guido Alves, Jan Petter Larsen & Simon Geir Møller. (2013) New Insight into Neurodegeneration: the Role of Proteomics. Molecular Neurobiology 49:3, pages 1181-1199.
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I. Ferrer, I. López-Gonzalez, M. Carmona, E. Dalfó, A. Pujol & A. Martínez. (2012) Neurochemistry and the non-motor aspects of PD. Neurobiology of Disease 46:3, pages 508-526.
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Tiziana Alberio & Mauro Fasano. (2011) Proteomics in Parkinson's disease: An unbiased approach towards peripheral biomarkers and new therapies. Journal of Biotechnology 156:4, pages 325-337.
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Annika Öhrfelt, Henrik Zetterberg, Kerstin Andersson, Rita Persson, Dzemila Secic, Gunnar Brinkmalm, Anders Wallin, Ezra Mulugeta, Paul T. Francis, Eugeen Vanmechelen, Dag Aarsland, Clive Ballard, Kaj Blennow & Ann Westman-Brinkmalm. (2011) Identification of Novel α-Synuclein Isoforms in Human Brain Tissue by using an Online NanoLC-ESI-FTICR-MS Method. Neurochemical Research 36:11, pages 2029-2042.
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Kurt A. Jellinger. 2011. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders 194 223 .
Tiziana Alberio, Claudia Anchieri, Luca Piacentini, Giovanna Gentile, Maurizio Simmaco, Mara Biasin & Mauro Fasano. (2011) Proteomic characterization of Jurkat T leukemic cells after dopamine stimulation: A model of circulating dopamine-sensitive cells. Biochimie 93:5, pages 892-898.
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Ewan Morrison, John Thompson, Sally J. M. Williamson, Michael E. Cheetham & Philip A. Robinson. (2011) A simple cell based assay to measure Parkin activity. Journal of Neurochemistry 116:3, pages 342-349.
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Tiziana Alberio, Alessandra Maria Bossi, Alberto Milli, Elisa Parma, Marzia Bruna Gariboldi, Giovanna Tosi, Leonardo Lopiano & Mauro Fasano. (2010) Proteomic analysis of dopamine and α‐synuclein interplay in a cellular model of Parkinson’s disease pathogenesis. The FEBS Journal 277:23, pages 4909-4919.
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Tiziana Alberio, Monica Colapinto, Massimo Natale, Raffaella Ravizza, Marzia B. Gariboldi, Enrico M. Bucci, Leonardo Lopiano & Mauro Fasano. (2010) Changes in the two-dimensional electrophoresis pattern of the Parkinson's disease related protein DJ-1 in human SH-SY5Y neuroblastoma cells after dopamine treatment. IUBMB Life 62:9, pages 688-692.
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Li Rebekah Feng, Howard J. Federoff, Stefano Vicini & Kathleen A. Maguire‐Zeiss. (2010) α‐Synuclein mediates alterations in membrane conductance: a potential role for α‐synuclein oligomers in cell vulnerability. European Journal of Neuroscience 32:1, pages 10-17.
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Virginie Licker, Enikö Kövari, Denis F. Hochstrasser & Pierre R. Burkhard. (2009) Proteomics in human Parkinson's disease research. Journal of Proteomics 73:1, pages 10-29.
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Alex Bayés & Seth G. N. Grant. (2009) Neuroproteomics: understanding the molecular organization and complexity of the brain. Nature Reviews Neuroscience 10:9, pages 635-646.
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Silvia Mila, Alessandra Giuliano Albo, Davide Corpillo, Sabrina Giraudo, Maurizio Zibetti, Enrico M Bucci, Leonardo Lopiano & Mauro Fasano. (2009) Lymphocyte proteomics of Parkinson’s disease patients reveals cytoskeletal protein dysregulation and oxidative stress. Biomarkers in Medicine 3:2, pages 117-128.
Crossref
Annika Öhrfelt, Pierre Grognet, Niels Andreasen, Anders Wallin, Eugeen Vanmechelen, Kaj Blennow & Henrik Zetterberg. (2009) Cerebrospinal fluid α-synuclein in neurodegenerative disorders—A marker of synapse loss?. Neuroscience Letters 450:3, pages 332-335.
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Cristina Ruiz-Romero & Francisco J. Blanco. (2009) Mitochondrial proteomics and its application in biomedical research. Molecular BioSystems 5:10, pages 1130.
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Andrew K. Ottens. 2009. Neuroproteomics. Neuroproteomics 1 21 .
Mauro FasanoTiziana AlberioLeonardo Lopiano. (2008) Peripheral biomarkers of Parkinson’s disease as early reporters of central neurodegeneration. Biomarkers in Medicine 2:5, pages 465-478.
Crossref

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