Advanced search
Publication Cover
Expert Review of Clinical Immunology Volume 1, 2005 - Issue 4
Submit an article Journal homepage
63
Views
15
CrossRef citations to date
0
Altmetric
Review

Overcoming the immunologic response to foreign enzymes in cancer therapy

Kerry A Chester Department of Oncology, Hampstead Campus, Royal Free and University College Medical School, UCL, Rowland Hill Street, London NW3 2PF, UK. [email protected]
,
Matthew Baker Antitope Ltd, Babraham Institute, Babraham, Cambridge, CB2 4AT, UK
&
Astrid Mayer Department of Oncology, Hampstead Campus, Royal Free and University College Medical School, UCL, Rowland Hill Street, London NW3 2PF, UK
Pages 549-559 | Published online: 10 Jan 2014

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Surinder K. Sharma & Kenneth D. Bagshawe. (2017) Translating antibody directed enzyme prodrug therapy (ADEPT) and prospects for combination. Expert Opinion on Biological Therapy 17:1, pages 1-13.
Read now

Articles from other publishers (14)

Sheron Latcha & Chintan V. Shah. (2022) Rescue Therapies for AKI in Onconephrology: Rasburicase and Glucarpidase. Seminars in Nephrology 42:6, pages 151342.
Crossref
Ramakrishna Boyanapalli, Inderpal Singh & Morse Faria. 2022. An Introduction to Bioanalysis of Biopharmaceuticals. An Introduction to Bioanalysis of Biopharmaceuticals 131 155 .
Zuben E. Sauna, Daniel Lagassé, Joao Pedras-Vasconcelos, Basil Golding & Amy S. Rosenberg. (2018) Evaluating and Mitigating the Immunogenicity of Therapeutic Proteins. Trends in Biotechnology 36:10, pages 1068-1084.
Crossref
Surinder K. Sharma & Kenneth D. Bagshawe. (2017) Antibody Directed Enzyme Prodrug Therapy (ADEPT): Trials and tribulations. Advanced Drug Delivery Reviews 118, pages 2-7.
Crossref
Dhadchayini Jeyaharan, Philip Aston, Angela Garcia-Perez, James Schouten, Paul Davis & Ann M. Dixon. (2016) Soluble expression, purification and functional characterisation of carboxypeptidase G2 and its individual domains. Protein Expression and Purification 127, pages 44-52.
Crossref
Katherine C. Allen, Amanda H. Champlain, Jonathan A. Cotliar, Steven M. Belknap, Dennis P. West, Jayesh Mehta & Steven M. Trifilio. (2015) Risk of Anaphylaxis with Repeated Courses of Rasburicase: A Research on Adverse Drug Events and Reports (RADAR) Project. Drug Safety 38:2, pages 183-187.
Crossref
Surinder K. Sharma, Kerry A. Chester & Kenneth D. Bagshawe. 2014. Handbook of Therapeutic Antibodies. Handbook of Therapeutic Antibodies 475 486 .
Hasanein Al-Hasani & Euthalia Roussou. (2011) Methotrexate for rheumatoid arthritis patients who are on hemodialysis. Rheumatology International 31:12, pages 1545-1547.
Crossref
Carima Andrady, Surinder K Sharma & Kerry A Chester. (2011) Antibody–enzyme fusion proteins for cancer therapy. Immunotherapy 3:2, pages 193-211.
Crossref
Surinder K. Sharma & Kenneth D. Bagshawe. 2010. Macromolecular Anticancer Therapeutics. Macromolecular Anticancer Therapeutics 393 406 .
Tim D. Jones, Laura J. Crompton, Frank J. Carr & Matthew P. Baker. 2009. Therapeutic Antibodies. Therapeutic Antibodies 405 423 .
Surinder K. Sharma, Kerry A. Chester & Kenneth D. Bagshawe. 2007. Handbook of Therapeutic Antibodies. Handbook of Therapeutic Antibodies 501 513 .
Astrid Mayer, Roslyn J. Francis, Surinder K. Sharma, Berend Tolner, Caroline J. Springer, Jan Martin, Geoff M. Boxer, James Bell, Alan J. Green, John A. Hartley, Clare Cruickshank, Julie Wren, Kerry A. Chester & Richard H.J. Begent. (2006) A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol Mustard Prodrug. Clinical Cancer Research 12:21, pages 6509-6516.
Crossref
Maoliang Wang, Amartya Basu, Thomas Palm, Jack Hua, Stephen Youngster, Lisa Hwang, Hsien-Ching Liu, Xiguang Li, Ping Peng, Yue Zhang, Hong Zhao, Zhihua Zhang, Clifford Longley, Mary Mehlig, Virna Borowski, Prakash Sai, Manickam Viswanathan, Eun Jang, Gerald Petti, Sam Liu, Karen Yang & David Filpula. (2006) Engineering an Arginine Catabolizing Bioconjugate:  Biochemical and Pharmacological Characterization of PEGylated Derivatives of Arginine Deiminase from Mycoplasma arthritidis . Bioconjugate Chemistry 17:6, pages 1447-1459.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.