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Expert Review of Ophthalmology Volume 8, 2013 - Issue 4
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Drug Profile

Cysteamine ophthalmic solution 0.44% for the treatment of corneal cystine crystals in cystinosis

Nancy Huynh Clinical Trials Branch, Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA; Clinical Trials Branch, Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA
,
William A Gahl Section of Human Biochemical Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA; Section of Human Biochemical Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
&
Rachel J Bishop Clinical Trials Branch, Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA. [email protected]; Clinical Trials Branch, Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD, USA. [email protected]
Pages 341-345 | Published online: 09 Jan 2014

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Phillip Dixon & Anuj Chauhan. (2019) Carbon Black Tinted Contact Lenses for Reduction of Photophobia in Cystinosis Patients. Current Eye Research 44:5, pages 497-504.
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Achini K Makuloluwa & Fatemeh Shams. (2018) Cysteamine hydrochloride eye drop solution for the treatment of corneal cystine crystal deposits in patients with cystinosis: an evidence-based review. Clinical Ophthalmology 12, pages 227-236.
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Articles from other publishers (22)

Mitchell Ross & Heather Sheardown. (2023) Application of Thermogels to the Anterior of the Eye as Alternatives to Conventional Eyedrops. Advanced Therapeutics 6:8.
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A.L. Minella, M.I. Casanova, T.J. Chokshi, J. Kang, K. Cosert, M.M. Gragg, M.A. Bowman, M.E. Mccorkell, N.L. Daley, B.C. Leonard, C.J. Murphy, V.K. Raghunathan & S.M. Thomasy. (2023) The TGM2 inhibitor cysteamine hydrochloride does not impact corneal epithelial and stromal wound healing in vitro and in vivo. Experimental Eye Research 226, pages 109338.
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Mitchell Ross, Jonathan Mofford, Jennifer JingYuan Tian, Benjamin Muirhead, Emily Anne Hicks, Lindsay Sheardown & Heather Sheardown. (2023) Thermo-responsive and mucoadhesive gels for the treatment of cystinosis. Biomaterials Advances 144, pages 213235.
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Emma Hector, Donald Cairns & G. Michael Wall. (2022) Evaluation of NACA and diNACA in human cystinosis fibroblast cell cultures as potential treatments for cystinosis. Orphanet Journal of Rare Diseases 17:1.
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Jorge Jimenez, Jayde L. Resnick, Ahmad B. Chaudhry, Ilya Gertsman, Ken K. Nischal & Morgan V. DiLeo. (2022) Ocular biodistribution of cysteamine delivered by a sustained release microsphere/thermoresponsive gel eyedrop. International Journal of Pharmaceutics 624, pages 121992.
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Francesco Emma & Elena Levtchenko. 2022. Tubulointerstitial Nephritis. Tubulointerstitial Nephritis 161 169 .
Elena Levtchenko, William A. Gahl & Francesco Emma. 2022. Pediatric Nephrology. Pediatric Nephrology 877 901 .
Zeba A. Syed, Beeran B. Meghpara, Kristin M. Hammersmith & Christopher J. Rapuano. 2022. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 149 186 .
Jorge Jimenez, Michael A. Washington, Jayde L. Resnick, Ken K. Nischal & Morgan V. Fedorchak. (2021) A sustained release cysteamine microsphere/thermoresponsive gel eyedrop for corneal cystinosis improves drug stability. Drug Delivery and Translational Research 11:5, pages 2224-2238.
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Hong Liang, Antoine Labbé, Christophe Baudouin, Celine Plisson & Vincenzo Giordano. (2021) Long-term follow-up of cystinosis patients treated with 0.55% cysteamine hydrochloride. British Journal of Ophthalmology 105:5, pages 608-613.
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Sukhmandeep Kaur, Phulen Sarma, Hardeep Kaur, Manisha Prajapat, Nishant Shekhar, Jaimini Bhattacharyya, Harpinder Kaur, Subodh Kumar, Bikash Medhi, Jagat Ram, Dipankar Das, Pramod Avti, Ajay Prakash, Rahul Singh & Anusuya Bhattacharyya. (2021) Efficacy and Safety of Topical Cysteamine in Corneal Cystinosis: A Systematic Review and Meta-Analysis. American Journal of Ophthalmology 223, pages 275-285.
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Elena Levtchenko, William A. Gahl & Francesco Emma. 2020. Pediatric Nephrology. Pediatric Nephrology 1 25 .
Zeba A. Syed, Beeran B. Meghpara, Kristin M. Hammersmith & Christopher J. Rapuano. 2020. Albert and Jakobiec's Principles and Practice of Ophthalmology. Albert and Jakobiec's Principles and Practice of Ophthalmology 1 38 .
Carla Atallah, Hélène Greige-Gerges & Catherine Charcosset. (2020) Development of cysteamine loaded liposomes in liquid and dried forms for improvement of cysteamine stability. International Journal of Pharmaceutics 589, pages 119721.
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Jorge Jimenez, Meera Sakthivel, Kanwal K. Nischal & Morgan V. Fedorchak. (2019) Drug delivery systems and novel formulations to improve treatment of rare corneal disease. Drug Discovery Today 24:8, pages 1564-1574.
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Susmito Biswas, Martha Gaviria, Luísa Malheiro, João Pedro Marques, Vincenzo Giordano & Hong Liang. (2018) Latest Clinical Approaches in the Ocular Management of Cystinosis: A Review of Current Practice and Opinion from the Ophthalmology Cystinosis Forum. Ophthalmology and Therapy 7:2, pages 307-322.
Crossref
Phillip Dixon, Kristin Powell & Anuj Chauhan. (2018) Novel approaches for improving stability of cysteamine formulations. International Journal of Pharmaceutics 549:1-2, pages 466-475.
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Lynda McEvoy. (2017) Ophthalmology Cystinosis Forum Morning Session. EMJ Nephrology, pages 2-9.
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William A. Gahl & Galina Nesterova. 2016. Pediatric Nephrology. Pediatric Nephrology 1329 1353 .
Branko Radojkovic. (2015) Cysteamine eye drops in the treatment of cystinosis - an Australian perspective. Journal of Pharmacy Practice and Research 45:4, pages 440-445.
Crossref
William A. Gahl & Galina Nesterova. 2014. Pediatric Nephrology. Pediatric Nephrology 1 28 .
Andrea Minella, Marie Isabel Casanova, Tanvi Chokshi, Jennifer Kang, Krista Cosert, Megan Gragg, Morgan Bowman, Michelle Mccorkell, Nicole Daley, Brian Leonard, Christopher Murphy, VijayKrishna Raghunathan & Sara Thomasy. (2022) The TGM2 Inhibitor Cysteamine Hydrochloride Does Not Impact Corneal Epithelial and Stromal Wound Healing in Vitro and in Vivo. SSRN Electronic Journal.
Crossref

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