422
Views
45
CrossRef citations to date
0
Altmetric
Review

The novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapy

&
Pages 125-133 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Sarah Kraus, Ajay Goel & Nadir Arber. (2010) Blood-based peptide, genetic, and epigenetic biomarkers for diagnosing gastrointestinal cancers. Expert Opinion on Medical Diagnostics 4:6, pages 459-471.
Read now
Shiran Shapira, Victoria Lisiansky, Nadir Arber & Sarah Kraus. (2010) Targeted immunotherapy for colorectal cancer: monoclonal antibodies and immunotoxins. Expert Opinion on Investigational Drugs 19:sup1, pages S67-S77.
Read now

Articles from other publishers (43)

Guanxuan Chen, Wanqi Zhu, Yang Liu, Liwen Zhang, Li Xie, Xingguo Song & Xianrang Song. (2023) The clonal heterogeneity of colon cancer with liver metastases. Journal of Gastroenterology 58:7, pages 642-655.
Crossref
Joanna Radzikowska, Anna M. Czarnecka, Teresa Klepacka, Magdalena Rychłowska-Pruszyńska, Anna Raciborska, Bożenna Dembowska-Bagińska, Maciej Pronicki, Andrzej Kukwa, Wojciech Fendler, Urszula Smyczyńska, Wojciech Kukwa & Antoni Krzeski. (2022) Cancer Stem Cell Markers in Rhabdomyosarcoma in Children. Diagnostics 12:8, pages 1895.
Crossref
Shiran Shapira, Gal Aiger, Amitay Ohayon, Dina Kazanov, Fatin Mdah, Marina Ben Shimon, Mori Hay-Levy, Lian Banon, Ido Laskov, Jacob Mashiah, Shahar Lev-Ari & Nadir Arber. (2021) Predictors of the CD24/CD11b Biomarker among Healthy Subjects. Journal of Personalized Medicine 11:9, pages 939.
Crossref
Chiao-Yun Lin, Chia-Lung Tsai, Angel Chao, Li-Yu Lee, Wei-Chun Chen, Yun-Hsin Tang, An-Shine Chao & Chyong-Huey Lai. (2021) Nucleophosmin/B23 promotes endometrial cancer cell escape from macrophage phagocytosis by increasing CD24 expression. Journal of Molecular Medicine 99:8, pages 1125-1137.
Crossref
Marei Sammar, Monika Siwetz, Hamutal Meiri, Adi Sharabi-Nov, Peter Altevogt & Berthold Huppertz. (2021) Reduced Placental CD24 in Preterm Preeclampsia Is an Indicator for a Failure of Immune Tolerance. International Journal of Molecular Sciences 22:15, pages 8045.
Crossref
Shiran Shapira, Dina Kazanov, Fatin Mdah, Hadas Yaakobi, Yair Herishanu, Chava Perry, Irit Avivi, Gilad Itchaki, Adi Shacham-Abulafia, Pia Raanani, Mori Hay-Levy, Gal Aiger, Jacob Mashiah, Shahar Lev-Ari & Nadir Arber. (2021) Feasibly of CD24/CD11b as a Screening Test for Hematological Malignancies. Journal of Personalized Medicine 11:8, pages 724.
Crossref
Eyal Sagiv & Michael A. Portman. (2021) CD24 for Cardiovascular Researchers: A Key Molecule in Cardiac Immunology, Marker of Stem Cells and Target for Drug Development. Journal of Personalized Medicine 11:4, pages 260.
Crossref
Peter Altevogt, Marei Sammar, Laura Hüser & Glen Kristiansen. (2020) Novel insights into the function of CD24 : A driving force in cancer . International Journal of Cancer 148:3, pages 546-559.
Crossref
Shiran Shapira, Dina Kazanov, Rachel Dankner, Sigal Fishman, Naftali Stern & Nadir Arber. (2021) High Expression Level of PPARγ in CD24 Knockout Mice and Gender-Specific Metabolic Changes: A Model of Insulin-Sensitive Obesity. Journal of Personalized Medicine 11:1, pages 50.
Crossref
文霞 马. (2021) Research Progress of CD24 in Gastric Cancer. Advances in Clinical Medicine 11:06, pages 2678-2684.
Crossref
Peter Altevogt, Marei Sammar, Laura Hüser, Viktor Umansky & Jochen Utikal. (2020) Perspective – Escape from destruction: how cancer-derived EVs are protected from phagocytosis. Trillium Exctracellular Vesicles 2:1, pages 60-64.
Crossref
. 2019. Malignant Pleural Mesothelioma. Malignant Pleural Mesothelioma 57 90 .
John Henry OwenChristine M. KomarckAnthony C. Wang, Waleed M. AbuzeidRichard F. Keep, Erin L. McKeanStephen Sullivan, Xing Fan & Mark E. P. Prince. (2018) UM-Chor1: establishment and characterization of the first validated clival chordoma cell line. Journal of Neurosurgery 128:3, pages 701-709.
Crossref
Limor Avivi-Arber, Doran Avivi, Marilena Perez, Nadir Arber & Shiran Shapira. (2018) Impaired bone healing at tooth extraction sites in CD24-deficient mice: A pilot study. PLOS ONE 13:2, pages e0191665.
Crossref
Yong Wha Moon, Hee-Jung An, Ja Seung Koo, Gun Min Kim, Hyunju Han, Seho Park, Seung Il Kim, Hyung Seok Park, Sewha Kim, Seung Ki Kim, Seung Ah Lee, Sohyun Hwang, Gun Woo Son & Joohyuk Sohn. (2017) CD44/CD24 and aldehyde dehydrogenase 1 in estrogen receptor-positive early breast cancer treated with tamoxifen: CD24 positivity is a poor prognosticator. Oncotarget 9:2, pages 2622-2630.
Crossref
Marei Sammar, Monika Siwetz, Hamutal Meiri, Viktor Fleming, Peter Altevogt & Berthold Huppertz. (2016) Expression of CD24 and Siglec-10 in first trimester placenta: implications for immune tolerance at the fetal–maternal interface. Histochemistry and Cell Biology 147:5, pages 565-574.
Crossref
Yushan Zhang, Hamsa Thayele Purayil, Joseph B. Black, Francis Fetto, Lauren D. Lynch, Jude N. Masannat & Yehia Daaka. (2017) Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis. Cancer Letters 391, pages 50-58.
Crossref
Xinying Wang, Yu Zhang, Yingying Zhao, Yanling Liang, Cheng Xiang, Huanyu Zhou, Hui Zhang, Qiang Zhang, Haitao Qing, Bo Jiang, Huabao Xiong & Liang Peng. (2016) CD24 promoted cancer cell angiogenesis via Hsp90-mediated STAT3/VEGF signaling pathway in colorectal cancer. Oncotarget 7:34, pages 55663-55676.
Crossref
Shiran Shapira, Shlomo Pleban, Diana Kazanov, Peter Tirosh & Nadir Arber. (2016) Terpinen-4-ol: A Novel and Promising Therapeutic Agent for Human Gastrointestinal Cancers. PLOS ONE 11:6, pages e0156540.
Crossref
Xin Wan, Ci Cheng, Qing Shao, Zhe Lin, Shuai Lu & Yun Chen. (2015) CD24 promotes HCC progression via triggering Notch-related EMT and modulation of tumor microenvironment. Tumor Biology 37:5, pages 6073-6084.
Crossref
Ilana Kaplan, Ilana Nabiochtchikov, Ari Leshno, Menachem Moshkowitz, Benjamin Shlomi, Shlomi Kleinman, Yaniv Dagan, Yaacob Meshiach, Lior Galazan, Nadir Arber, Limor Avivi-Arber & Sarah Kraus. (2015) Association of CD24 and the adenomatous polyposis coli gene polymorphisms with oral lichen planus. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 120:3, pages 378-385.
Crossref
Stefan Huber, Anja K. Wege, Günther Bernhardt, Armin Buschauer & Gero Brockhoff. (2015) Topotecan-induced ABCG2 expression in MCF-7 cells is associated with decreased CD24 and EpCAM expression and a loss of tumorigenicity. Cytometry Part A 87:8, pages 707-716.
Crossref
YUE DU, HAIHONG ZHANG, ZHONGMIN JIANG, GUOWEI HUANG, WENLI LU & HESHENG WANG. (2015) Expression of L1 protein correlates with cluster of differentiation 24 and integrin β1 expression in gastrointestinal stromal tumors. Oncology Letters 9:6, pages 2595-2602.
Crossref
Inna Naumov, Alona Zilberberg, Shiran Shapira, Doran Avivi, Dina Kazanov, Rina Rosin-Arbesfeld, Nadir Arber & Sarah Kraus. (2014) CD24 knockout prevents colorectal cancer in chemically induced colon carcinogenesis and in APC Min /CD24 double knockout transgenic mice . International Journal of Cancer 135:5, pages 1048-1059.
Crossref
D. Andreadis, A. Bakopoulou, G. Leyhausen, A. Epivatianos, J. Volk, A. Markopoulos & W. Geurtsen. (2013) Minor salivary glands of the lips: a novel, easily accessible source of potential stem/progenitor cells. Clinical Oral Investigations 18:3, pages 847-856.
Crossref
Eran Sadot, Sarah Kraus, Michael Stein, Ilana Naboishchikov, Ohad Toledano, Dina Kazanov, Nadir Arber & Hanoch Kashtan. (2018) CD24 Gene Polymorphism - A Novel Prognostic Factor in Esophageal Cancer . The International Journal of Biological Markers 29:1, pages e49-e54.
Crossref
Tal Sella, Ben Boursi, Amira Gat-Charlap, Ilan Aroch, Eliezer Liberman, Menachem Moshkowitz, Ehud Miller, Eyal Gur, Roy Inbar, Arye Blachar, Nicola J. Mabjeesh, Olivia Rosenfeld, Fanny Sperber, Vadim Reiser, Shlomi Kleinman, Ariel J. Jaffa, Miki Bloch, Mati Ormianer, Inna Naumov, Diana Kazanov, Sarah Kraus, Lior Galazan & Nadir Arber. (2013) One stop screening for multiple cancers: The experience of an integrated cancer prevention center. European Journal of Internal Medicine 24:3, pages 245-249.
Crossref
Kyu Sub Kang, Yoon Pyo Choi, Ming-Qing Gao, Suki Kang, Baek Gil Kim, Joo Hyun Lee, Mi Jeong Kwon, Young Kee Shin & Nam Hoon Cho. (2013) CD24+ ovary cancer cells exhibit an invasive mesenchymal phenotype. Biochemical and Biophysical Research Communications 432:2, pages 333-338.
Crossref
P. Mehdipour & N. Parsa. 2013. Telomere Territory and Cancer. Telomere Territory and Cancer 163 188 .
Jonathan B. OverdevestKristina H. Knubel, Jason E. Duex, Shibu ThomasMatthew D. NitzMichael A. HardingSteven C. SmithHenry F. Frierson, Mark ConawayDan Theodorescu. (2012) CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated. Proceedings of the National Academy of Sciences 109:51.
Crossref
Ehud Miller, Shiran Shapira, Eyal Gur, Inna Naumov, Dina Kazanov, David Leshem, Yoav Barnea, Yaakov Meshiach, Andrea Gat, Daniel Sion, Nadir Arber & Sarah Kraus. (2018) Increased expression of CD24 in nonmelanoma skin cancer. The International Journal of Biological Markers 27:4, pages 331-336.
Crossref
Thomas B. Brunner, Leoni A. Kunz-Schughart, Philipp Grosse-Gehling & Michael Baumann. (2012) Cancer Stem Cells as a Predictive Factor in Radiotherapy. Seminars in Radiation Oncology 22:2, pages 151-174.
Crossref
William P. Cawthorn, Erica L. Scheller & Ormond A. MacDougald. (2012) Adipose tissue stem cells meet preadipocyte commitment: going back to the future. Journal of Lipid Research 53:2, pages 227-246.
Crossref
Jianping Deng, Guodong Gao, Liang Wang, Tao Wang, Jia Yu & Zhenwei Zhao. (2012) CD24 Expression as a Marker for Predicting Clinical Outcome in Human Gliomas. Journal of Biomedicine and Biotechnology 2012, pages 1-7.
Crossref
Jin Zheng, Yan Li, Jiandong Yang, Qiang Liu, Ming Shi, Rui Zhang, Hengjun Shi, Qinyou Ren, Ji Ma, Hang Guo, Yurong Tao, Yan Xue, Ning Jiang, Libo Yao & Wenchao Liu. (2011) NDRG2 inhibits hepatocellular carcinoma adhesion, migration and invasion by regulating CD24 expression. BMC Cancer 11:1.
Crossref
Shiran Shapira, Dina Kazanov, Samuel Weisblatt, Alex Starr, Nadir Arber & Sarah Kraus. (2011) The CD24 Protein Inducible Expression System Is an Ideal Tool to Explore the Potential of CD24 as an Oncogene and a Target for Immunotherapy in Vitro and in Vivo. Journal of Biological Chemistry 286:47, pages 40548-40555.
Crossref
Shiran Shapira, Assaf Shapira, Alex Starr, Dina Kazanov, Sarah Kraus, Itai Benhar & Nadir Arber. (2011) An Immunoconjugate of Anti-CD24 and Pseudomonas Exotoxin Selectively Kills Human Colorectal Tumors in Mice. Gastroenterology 140:3, pages 935-946.
Crossref
Bo Liu, Yangde Zhang, Mingmei Liao, Zhansheng Deng, Liansheng Gong, Jiarui Jiang, Ling Lynn, Kai Wu & Xiongying Miao. (2010) Clinicopathologic and Prognostic Significance of CD24 in Gallbladder Carcinoma. Pathology & Oncology Research 17:1, pages 45-50.
Crossref
Neveen Said & Dan Theodorescu. 2012. Signaling Pathways and Molecular Mediators in Metastasis. Signaling Pathways and Molecular Mediators in Metastasis 331 345 .
Sibel Bektas, Burak Bahadir, Bulent Hamdi Ucan & Sukru Oguz Ozdamar. (2010) CD24 and Galectin-1 Expressions in Gastric Adenocarcinoma and Clinicopathologic Significance. Pathology & Oncology Research 16:4, pages 569-577.
Crossref
Xiaolong WeiDavid Dombkowski, Katia MeirellesRafael Pieretti-VanmarckePaul P. SzotekHenry L. ChangFrederic I. Preffer, Peter R. Mueller, Jose Teixeira, David T. MacLaughlinPatricia K. Donahoe. (2010) Müllerian inhibiting substance preferentially inhibits stem/progenitors in human ovarian cancer cell lines compared with chemotherapeutics. Proceedings of the National Academy of Sciences 107:44, pages 18874-18879.
Crossref
Elisabetta Fersini, E. Messina, F. Archetti & C. Manfredotti. (2010) Combining Gene Expression Profiles and Drug Activity Patterns Analysis: A Relational Clustering Approach. Journal of Mathematical Modelling and Algorithms 9:3, pages 275-289.
Crossref
Ivyna Bong Pau Ni, Zubaidah Zakaria, Rohaizak Muhammad, Norlia Abdullah, Naqiyah Ibrahim, Nor Aina Emran, Nor Hisham Abdullah & Sharifah Noor Akmal Syed Hussain. (2010) Gene expression patterns distinguish breast carcinomas from normal breast tissues: The Malaysian context. Pathology - Research and Practice 206:4, pages 223-228.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.