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Expert Review of Clinical Pharmacology Volume 1, 2008 - Issue 6
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Review

Design and analysis considerations for thorough QT studies employing conventional (10 s, 12-lead) ECG recordings

Charles M Beasley Jr Lilly Corporate Center, Indianapolis, IN 46285, USA. [email protected]
,
Alex Dmitrienko Lilly Corporate Center, Indianapolis, IN 46285, USA
&
Malcolm I Mitchell Lilly Corporate Center, Indianapolis, IN 46285, USA
Pages 815-839 | Published online: 10 Jan 2014

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Icilio Cavero & Henry Holzgrefe. (2014) Comprehensive in vitro Proarrhythmia Assay, a novel in vitro/in silico paradigm to detect ventricular proarrhythmic liability: a visionary 21st century initiative. Expert Opinion on Drug Safety 13:6, pages 745-758.
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Articles from other publishers (5)

Rashmi R. Shah & Joel Morganroth. (2012) Early Investigation of QTc Liability. Drug Safety 35:9, pages 695-709.
Crossref
Rashmi R. Shah & Joel Morganroth. (2012) Early Investigation of QTc Liability. Drug Safety 35:9, pages 695-709.
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Arne Ring, Andreas Port, E. Ulrike Graefe-Mody, Ivette Revollo, Mario Iovino & Klaus A. Dugi. (2011) The DPP-4 inhibitor linagliptin does not prolong the QT interval at therapeutic and supratherapeutic doses. British Journal of Clinical Pharmacology 72:1, pages 39-50.
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Lawrence Z. Satin, Todd A. Durham & J. Rick Turner. (2011) Assessing a Drug’s Proarrhythmic Liability: An Overview of Computer Simulation Modeling, Nonclinical Assays, and the Thorough QT/QTc Study. Drug Information Journal 45:3, pages 357-375.
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J. Rick TurnerJ. Rick Turner. 2010. New Drug Development. New Drug Development 195 210 .

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