Advanced search
Publication Cover
Expert Review of Clinical Pharmacology Volume 2, 2009 - Issue 1
Submit an article Journal homepage
168
Views
33
CrossRef citations to date
0
Altmetric
Drug Profile

Sugammadex: a novel selective relaxant binding agent

Mohamed Naguib Department of Anesthesiology and Pain Medicine, The University of Texas MD Anderson Cancer Center, 1400 Holcombe Boulevard, Houston, TX 77003, USA. [email protected]
&
Sorin J Brull Mayo Clinic College of Medicine, Jacksonville, FL 32082, USA
Pages 37-53 | Published online: 10 Jan 2014

Citations (33)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Don B. Headley, Antonio G. Martins, Kevin J. McShane & David A. Grossblat. (2023) Diaphragm pacing using the minimally invasive cervical approach. The Journal of Spinal Cord Medicine 46:1, pages 26-34.
Read now
Stefan Josef Schaller & Heidrun Lewald. (2016) Clinical pharmacology and efficacy of sugammadex in the reversal of neuromuscular blockade. Expert Opinion on Drug Metabolism & Toxicology 12:9, pages 1097-1108.
Read now
Stephen Aniskevich, Bruce J Leone & Sorin J Brull. (2011) Sugammadex: a novel approach to reversal of neuromuscular blockade. Expert Review of Neurotherapeutics 11:2, pages 185-198.
Read now
Sorin J Brull & Mohamed Naguib. (2009) Selective reversal of muscle relaxation in general anesthesia: focus on sugammadex. Drug Design, Development and Therapy 3, pages 119-129.
Read now

Articles from other publishers (29)

Hyo Jung Son & Ukjin Jeong. (2022) A short review of adverse events of sugammadex. Medical Biological Science and Engineering 5:2, pages 52-56.
Crossref
Teng Meng Sheng & Palanirajan Vijayaraj Kumar. (2022) A New Approach for β-cyclodextrin Conjugated Drug Delivery System in Cancer Therapy. Current Drug Delivery 19:3, pages 266-300.
Crossref
Vicente Muedra, Vicent Rodilla, Marta Llansola, Ana Agustí, Clara Pla, Antolín Canto & Vicente Hernández-Rabaza. (2022) Potential Neuroprotective Role of Sugammadex: A Clinical Study on Cognitive Function Assessment in an Enhanced Recovery After Cardiac Surgery Approach and an Experimental Study. Frontiers in Cellular Neuroscience 16.
Crossref
Tao Zhuang, Yin Chen, Junyi Xu, Zhaoyang Qi, Jiaqi Ye, Cangcang Xu, Wei Du, Bifeng Liu & Guisen Zhang. (2021) Isolation, structural characterization and quality control strategy of an unknown process-related impurity in sugammadex sodium. Journal of Pharmaceutical and Biomedical Analysis 200, pages 114072.
Crossref
J. Ross Renew, Robert Ratzlaff, Vivian Hernandez-Torres, Sorin J. Brull & Richard C. Prielipp. (2020) Neuromuscular blockade management in the critically Ill patient. Journal of Intensive Care 8:1.
Crossref
Sarah Kyuragi Luthe & Hajime Iwasaki. (2020) The Financial and Humanistic Costs Associated with Residual Neuromuscular Blockade. Current Anesthesiology Reports 10:3, pages 242-250.
Crossref
Na Young Kim, Jae Chul Koh, Ki-Young Lee, Sung Soo Kim, Jung Hwa Hong, Hoon Jae Nam & Sun-Joon Bai. (2019) Influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium: A prospective, randomized, double-blinded, controlled study. Journal of Clinical Anesthesia 57, pages 97-102.
Crossref
Seok Kyeong Oh, Byung Gun Lim, Sungsoo Park, Hong Seuk Yang, Junyong In, Yong Beom Kim, Hey-ran Choi & Il Ok Lee. (2019) Effect of protracted dexamethasone exposure and its withdrawal on rocuronium-induced neuromuscular blockade and sugammadex reversal: an ex vivo rat study. Scientific Reports 9:1.
Crossref
Tak Kyu Oh, Ah-Young Oh, Jung-Hee Ryu, Bon-Wook Koo, In-Ae Song, Sun Woo Nam & Hee-Jung Jee. (2019) Retrospective analysis of 30-day unplanned readmission after major abdominal surgery with reversal by sugammadex or neostigmine. British Journal of Anaesthesia 122:3, pages 370-378.
Crossref
A.-M. Hristovska, P. Duch, M. Allingstrup & A. Afshari. (2018) The comparative efficacy and safety of sugammadex and neostigmine in reversing neuromuscular blockade in adults. A Cochrane systematic review with meta-analysis and trial sequential analysis. Anaesthesia 73:5, pages 631-641.
Crossref
Tae-Yun Sung, Hwang-Ju You, Choon-Kyu Cho, Hey Ran Choi, Yong Beom Kim, Yong Sup Shin & Hong Seuk Yang. (2018) Effects of magnesium chloride on rocuronium-induced neuromuscular blockade and sugammadex reversal in an isolated rat phrenic nerve–hemidiaphragm preparation. European Journal of Anaesthesiology 35:3, pages 193-199.
Crossref
Phatsawee Jansook, Noriko Ogawa & Thorsteinn Loftsson. (2018) Cyclodextrins: structure, physicochemical properties and pharmaceutical applications. International Journal of Pharmaceutics 535:1-2, pages 272-284.
Crossref
Ana-Marija Hristovska, Patricia Duch, Mikkel Allingstrup & Arash Afshari. (2017) Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults. Cochrane Database of Systematic Reviews.
Crossref
Sorin J. BrullAaron F. Kopman. (2017) Current Status of Neuromuscular Reversal and Monitoring. Anesthesiology 126:1, pages 173-190.
Crossref
Phennapha Saokham & Thorsteinn Loftsson. (2017) γ-Cyclodextrin. International Journal of Pharmaceutics 516:1-2, pages 278-292.
Crossref
Thorsteinn Loftsson, Maria D Moya-Ortega, Carmen Alvarez-Lorenzo & Angel Concheiro. (2016) Pharmacokinetics of cyclodextrins and drugs after oral and parenteral administration of drug/cyclodextrin complexes. Journal of Pharmacy and Pharmacology 68:5, pages 544-555.
Crossref
B.A. Baldo & N.J. McDonnell. (2014) Sugammadex and anaphylaxis in the operating theater. Revista Española de Anestesiología y Reanimación 61:5, pages 239-245.
Crossref
M. del-Rio-Vellosillo, J.J. Garcia-Medina & R. Martin-Gil-Parra. (2014) Anaesthetic management of a patient with Charcot–Marie–Tooth disease for staged diaphragmatic plication. British Journal of Anaesthesia 112:2, pages 390.
Crossref
Stuart Williams, David Stephen Nesvadba & Gordon Bathgate. (2014) Sugammadex for the treatment of rocuronium‐induced anaphylaxis. Anaesthesia Cases 2:1, pages 28-31.
Crossref
Mohamed Naguib. 2011. Anesthetic Pharmacology. Anesthetic Pharmacology 633 647 .
Mohamed Naguib, Sorin J. Brull & Hal R. Arkes. (2013) Reasoning of an Anomaly. Anesthesia & Analgesia 117:2, pages 297-300.
Crossref
R. W. Watts, J. A. London, R. M. A. W. van Wijk & Y.-L. Lui. (2012) The Influence of Unrestricted Use of Sugammadex on Clinical Anaesthetic Practice in a Tertiary Teaching Hospital. Anaesthesia and Intensive Care 40:2, pages 333-339.
Crossref
Milan Adamus, Lumir Hrabalek, Tomas Wanek, Tomas Gabrhelik & Jana Zapletalova. (2011) INFLUENCE OF AGE AND GENDER ON THE PHARMACODYNAMIC PARAMETERS OF ROCURONIUM DURING TOTAL INTRAVENOUS ANESTHESIA. Biomedical Papers 155:4, pages 347-353.
Crossref
Sorin J. Brull & Glenn S. Murphy. (2010) Residual Neuromuscular Block. Anesthesia & Analgesia 111:1, pages 129-140.
Crossref
Mohamed Naguib, Aaron F. Kopman, Cynthia A. Lien, Jennifer M. Hunter, Adriana Lopez & Sorin J. Brull. (2010) A Survey of Current Management of Neuromuscular Block in the United States and Europe. Anesthesia & Analgesia 111:1, pages 110-119.
Crossref
Amir Abrishami, Joyce Ho, Jean Wong, Ling Yin & Frances Chung. (2009) Sugammadex, a selective reversal medication for preventing postoperative residual neuromuscular blockade. Cochrane Database of Systematic Reviews.
Crossref
. (2009) Current World Literature. Current Opinion in Anaesthesiology 22:4, pages 539-546.
Crossref
Mohamed Naguib & Sorin J Brull. (2009) Update on neuromuscular pharmacology. Current Opinion in Anaesthesiology 22:4, pages 483-490.
Crossref
Shridhar Hegde & Michelle Schmidt. 2009. Annual Reports in Medicinal Chemistry Volume 44. Annual Reports in Medicinal Chemistry Volume 44 577 632 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.