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Drug Profile

Conbercept (KH-902) for the treatment of neovascular age-related macular degeneration

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Alessandro Arrigo & Francesco Bandello. (2021) Retinal vein occlusion: drug targets and therapeutic implications. Expert Opinion on Therapeutic Targets 25:10, pages 847-864.
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Huan Liu, Yue Ma, Hong-Chang Xu, Li-Ying Huang, Li-Ying Zhai & Xiao-Rong Zhang. (2020) Updates on the Management of Ocular Vasculopathies with VEGF Inhibitor Conbercept. Current Eye Research 45:12, pages 1467-1476.
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Dominique Bremond-Gignac. (2016) Investigational drugs for retinal vein occlusion. Expert Opinion on Investigational Drugs 25:7, pages 841-850.
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Michael W. Stewart. (2016) Extended release anti-VEGF systems: a strategy whose time has come? Or already gone?. Expert Review of Ophthalmology 11:3, pages 167-169.
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Articles from other publishers (24)

Liqin Gao, Yanping Song, Xiaodong Sun, Junjun Zhang, Yuling Liu, Youxin Chen, Zhifeng Wu, Ye Jian, Xiaoling Liu, Lin Lv, Shaojun Chen, Yu‐sheng Wang, Nan Chen, Xiao Ke & Feng Zhang. (2023) Safety and efficacy of intravitreal injection of conbercept for the treatment of patients with choroidal neovascularization secondary to pathological myopia: Results from the SHINY study . Acta Ophthalmologica.
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Xing Wang & Peng Wang. (2023) Spectral-domain optical coherence tomography combined with electroretinography in the assessment of conbercept for neovascular age-related macular degeneration: a preliminary study. Frontiers in Neuroscience 17.
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Yuling Zou, Weiwei Chen, Jia Chen & Zhipeng You. (2022) Vascular Endothelial Growth Factor Receptor 1 Facilitates the Effect of Macrophages on Human Umbilical Vein Endothelial Cells Migration by Regulating the M1 Polarization. Journal of Biomedical Nanotechnology 18:12, pages 2839-2845.
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Jianbo Mao, Caiyun Zhang, Shian Zhang, Chenyi Liu, Nuo Chen, Jiwei Tao, Xiangjun She, Zicheng Zheng, Zhe Lv & Lijun Shen. (2022) Predictors of anti‐VEGF efficacy in chronic central serous chorioretinopathy based on intraocular cytokine levels and pigment epithelium detachment subtypes . Acta Ophthalmologica 100:7.
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Marie Fabre, Lou Mateo, Diana Lamaa, Stéphanie Baillif, Gilles Pagès, Luc Demange, Cyril Ronco & Rachid Benhida. (2022) Recent Advances in Age-Related Macular Degeneration Therapies. Molecules 27:16, pages 5089.
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Yan Lu, Wenzhi Huang, Yuehong Zhang, Xiongfei Huang, Xu Zhang, Haizhi Ma, Guoliang Ren, Feng Shi, Lihui Kuang, Shigang Yan, Shuke Luo, Junyan Zhang, Jingfang He, Weizhong Yang, Zongyin Gao & Yunxia Leng. (2021) Factors for Visual Acuity Improvement After Anti-VEGF Treatment of Wet Age-Related Macular Degeneration in China: 12 Months Follow up. Frontiers in Medicine 8.
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Lu-Na Cheng, Yu-Xi Lin, Lei Liu, Xu-He Zhang, Yan-Qi Xue, Sheng-Di Zhou, Zhe-Li Liu & Han Zhang. (2020) Assessment of conbercept therapy for high myopia macular neovascularization by optical coherence tomography angiography. Scientific Reports 10:1.
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Feng He, Jingyun Yang, Xiao Zhang & Weihong Yu. (2020) Efficacy of conbercept combined with panretinal photocoagulation in the treatment of proliferative diabetic retinopathy. Scientific Reports 10:1.
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Xiao Zhang, Jie Wu, Chan Wu, Ai-ling Bian, Shuang Geng & Rong-ping Dai. (2020) Comparison of aqueous humor levels of PlGF and VEGF in proliferative diabetic retinopathy before and after intravitreal conbercept injection. Diabetes Research and Clinical Practice 162, pages 108083.
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Xun Li, Hongmei Luo, Cheng ZuoZirong Zhang, Junjun Zhang & Meixia Zhang. (2019) CONBERCEPT IN PATIENTS WITH TREATMENT-NAIVE NEOVASCULAR AGE-RELATED MACULAR DEGENERATION IN REAL-LIFE SETTING IN CHINA. Retina 39:7, pages 1353-1360.
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Jianbo Mao, Caiyun Zhang, Chenyi Liu, Lijun Shen, Jimeng Lao, Yirun Shao, Yiqi Chen & Jiwei Tao. (2019) The Efficacy of Intravitreal Conbercept for Chronic Central Serous Chorioretinopathy. Journal of Ophthalmology 2019, pages 1-5.
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Hacer Isildak, Stephen G. Schwartz & Harry W. Flynn. (2019) Pharmacotherapy of Myopic Choroidal Neovascularization. Current Pharmaceutical Design 24:41, pages 4853-4859.
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Mohammadreza Peyman, Alireza Peyman, Van C. Lansingh, Amirhossein Orandi & Visvaraja Subrayan. (2019) Intravitreal bevacizumab versus ranibizumab: Effects on the vessels of the fellow non-treated eye. Journal of Current Ophthalmology 31:1, pages 55-60.
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Dawei Zhang, Zahrah Khan & Tao Chai. (2019) Effect of conbercept or ranibizumab in the treatment of wet age-related macular degeneration. Environmental Disease 4:2, pages 50.
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Quan Zhang, Ting Zhang, Hong Zhuang, Zhongcui Sun & Yaowu Qin. (2019) Single-Dose Intravitreal Conbercept before Panretinal Photocoagulation as an Effective Adjunctive Treatment in Chinese Proliferative Diabetic Retinopathy. Ophthalmologica 242:2, pages 59-68.
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Xiao Zhang, Chan Wu, Li-jia Zhou & Rong-ping Dai. (2018) Observation of optic disc neovascularization using OCT angiography in proliferative diabetic retinopathy after intravitreal conbercept injections. Scientific Reports 8:1.
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Thiago Cabral, Luiz H. Lima, Luiz Guilherme M. Mello, Júlia Polido, Éverton P. Correa, Akiyoshi Oshima, Jimmy Duong, Pedro Serracarbassa, Caio V. Regatieri, Vinit B. Mahajan & Rubens Belfort Jr.. (2018) Bevacizumab Injection in Patients with Neovascular Age-Related Macular Degeneration Increases Angiogenic Biomarkers. Ophthalmology Retina 2:1, pages 31-37.
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Sheng Zhang, Xiaoping Gao, Wei Fu, Shengwei Li & Limin Yue. (2017) Immunoglobulin-like domain 4-mediated ligand-independent dimerization triggers VEGFR-2 activation in HUVECs and VEGFR2-positive breast cancer cells. Breast Cancer Research and Treatment 163:3, pages 423-434.
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Jia Li, Yannis M. Paulus, Yuanlu Shuai, Wangyi Fang, Qinghuai Liu & Songtao Yuan. (2017) New Developments in the Classification, Pathogenesis, Risk Factors, Natural History, and Treatment of Branch Retinal Vein Occlusion. Journal of Ophthalmology 2017, pages 1-18.
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Melania Olivieri, Emanuele Amata, Shila Vinciguerra, Jole Fiorito, Giovanni Giurdanella, Filippo Drago, Nunzia Caporarello, Orazio Prezzavento, Emanuela Arena, Loredana Salerno, Antonio Rescifina, Gabriella Lupo, Carmelina Daniela Anfuso & Agostino Marrazzo. (2016) Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells. Journal of Medicinal Chemistry 59:21, pages 9960-9966.
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Philip J. Rosenfeld. (2016) Optical Coherence Tomography and the Development of Antiangiogenic Therapies in Neovascular Age-Related Macular Degeneration. Investigative Opthalmology & Visual Science 57:9, pages OCT14.
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C. Tolou, L. Mahieu, V. Pagot-Mathis, F. Matonti & V. Soler. (2016) De la maculopathie à la dégénérescence maculaire liée à l’âge : modalités de suivi et de traitement. NPG Neurologie - Psychiatrie - Gériatrie 16:92, pages 92-100.
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V. Soler, L. Mahieu, V. Pagot-Mathis & F. Matonti. (2016) Maculopathie liées à l’âge et dégénérescence maculaire liée à l’âge. Qui surveiller ? Qui injecter ? Qui opérer ?Age-related maculopathy and age-related macular degeneration. Who to monitor? Who to inject? Who to operate on?. Les cahiers de l'année gérontologique 7:4, pages 188-196.
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Xue Luo, Yu-meng Shen, Meng-nan Jiang, Xiang-feng Lou & Yin Shen. (2015) Ocular Blood Flow Autoregulation Mechanisms and Methods. Journal of Ophthalmology 2015, pages 1-7.
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