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Drug Profiles

Dulaglutide (LY-2189265) for the treatment of type 2 diabetes

Pages 385-399 | Received 24 Jul 2015, Accepted 08 Jan 2016, Published online: 06 Feb 2016

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Read on this site (3)

André J. Scheen. (2017) Pharmacological management of type 2 diabetes: what’s new in 2017?. Expert Review of Clinical Pharmacology 10:12, pages 1383-1394.
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André J. Scheen. (2017) Dulaglutide for the treatment of type 2 diabetes. Expert Opinion on Biological Therapy 17:4, pages 485-496.
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Brian Tomlinson, Miao Hu, Yuzhen Zhang, Paul Chan & Zhong-Min Liu. (2016) Investigational glucagon-like peptide-1 agonists for the treatment of obesity. Expert Opinion on Investigational Drugs 25:10, pages 1167-1179.
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Articles from other publishers (15)

Changzhen Zhang, Guosheng Gao, Yafeng Li, Jingjing Ying, Jianhui Li & Supei Hu. (2023) Design of a Dual Agonist of Exendin-4 and FGF21 as a Potential Treatment for Type 2 Diabetes Mellitus and Obesity. Iranian Journal of Pharmaceutical Research 22:1.
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Songmao Zheng, David Polidori, Yuanping Wang, Brian Geist, Xiefan Lin‐Schmidt, Jennifer L. Furman, Serena Nelson, Andrea R. Nawrocki & Simon A. Hinke. (2023) A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model . Clinical and Translational Science.
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Yao Zhang, Yibing Wang & Junli Liu. (2023) Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective. Genes & Diseases 10:3, pages 825-847.
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José L. Górriz, Irene Romera, Amelia Cobo, Phillipe D. O’Brien & Juan F. Merino-Torres. (2022) Glucagon-Like Peptide-1 Receptor Agonist Use in People Living with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Narrative Review of the Key Evidence with Practical Considerations. Diabetes Therapy 13:3, pages 389-421.
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Huanbo Tan, Wencheng Su, Wenyu Zhang, Jie Zhang, Michael Sattler & Peijian Zou. (2021) Albumin-binding domain extends half-life of glucagon-like peptide-1. European Journal of Pharmacology 890, pages 173650.
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Alina Kondrashina, Shauna Heffernan, Nora O’Brien & Linda Giblin. 2021. Biologically Active Peptides. Biologically Active Peptides 629 664 .
Huanbo Tan, Wencheng Su, Wenyu Zhang, Pengju Wang, Michael Sattler & Peijian Zou. (2019) Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins. Current Pharmaceutical Design 24:41, pages 4932-4946.
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Raffaella Gentilella, Valeria Pechtner, Antonella Corcos & Agostino Consoli. (2019) Glucagon-like peptide-1 receptor agonists in type 2 diabetes treatment: are they all the same?. Diabetes/Metabolism Research and Reviews 35:1, pages e3070.
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Daoqi Tang, Hong Tian, Jicheng Wu, Jiaxiao Cheng, Cheng Luo, Wenbo Sai, Xiaoda Song, Xiangdong Gao & Wenbing Yao. (2018) C-terminal site-specific PEGylated Exendin-4 analog: A long-acting glucagon like Peptide-1 receptor agonist, on glycemic control and beta cell function in diabetic db/db mice. Journal of Pharmacological Sciences 138:1, pages 23-30.
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Takahiro Yajima, Kumiko Yajima, Makoto Hayashi, Hiroshi Takahashi & Keigo Yasuda. (2018) Improved glycemic control with once-weekly dulaglutide in addition to insulin therapy in type 2 diabetes mellitus patients on hemodialysis evaluated by continuous glucose monitoring. Journal of Diabetes and its Complications 32:3, pages 310-315.
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Caina Li, Shaocong Hou, Shuainan Liu, Yi Huan, Sujuan Sun, Quan Liu & Zhufang Shen. (2017) The albumin-exendin-4 recombinant protein E2HSA improves glycemic control and β-cell function in spontaneous diabetic KKAy mice. BMC Pharmacology and Toxicology 18:1.
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Ting-Ting Zhou, Fei Ma, Xiao-Fan Shi, Xin Xu, Te Du, Xiao-Dan Guo, Gai-Hong Wang, Liang Yu, Vatcharin Rukachaisirikul, Li-Hong Hu, Jing Chen & Xu Shen. (2017) DMT efficiently inhibits hepatic gluconeogenesis by regulating the Gαq signaling pathway. Journal of Molecular Endocrinology 59:2, pages 151-169.
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Hiroaki Seino, Yukiko Onishi, Yusuke Naito & Mitsuhisa Komatsu. (2016) Lixisenatide improves glycemic outcomes of Japanese patients with type 2 diabetes: a meta-analysis. Diabetology & Metabolic Syndrome 8:1.
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Brian M Moran, Aine M McKillop & Finbarr PM O’Harte. (2016) Development of novel ligands for peptide GPCRs. Current Opinion in Pharmacology 31, pages 57-62.
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Yanwei Li, Lin Li & Christian Hölscher. (2016) Incretin-based therapy for type 2 diabetes mellitus is promising for treating neurodegenerative diseases. Reviews in the Neurosciences 27:7, pages 689-711.
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