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Capturing the heterogeneity in systemic sclerosis with genome-wide expression profiling

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Pages 463-473 | Published online: 10 Jan 2014

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Vasiliki Liakouli, Jacopo Ciaffi, Francesco Ursini, Piero Ruscitti, Riccardo Meliconi, Francesco Ciccia, Paola Cipriani & Roberto Giacomelli. (2020) Efficacy and safety of imatinib mesylate in systemic sclerosis. A systematic review and meta-analysis. Expert Review of Clinical Immunology 16:9, pages 931-942.
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Francesco Bonella, Giuseppe Patuzzo & Claudio Lunardi. (2015) Biomarker discovery in systemic sclerosis: state of the art. Current Biomarker Findings 5, pages 47-68.
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Timothy RDJ Radstake. (2011) Novel insights in the pathogenesis of systemic sclerosis. Expert Review of Clinical Immunology 7:4, pages 389-390.
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Vesna Spasovski, Marina Andjelkovic, Marina Parezanovic, Jovana Komazec, Milena Ugrin, Kristel Klaassen & Maja Stojiljkovic. (2023) The Role of Autophagy and Apoptosis in Affected Skin and Lungs in Patients with Systemic Sclerosis. International Journal of Molecular Sciences 24:13, pages 11212.
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Rebekka Jerjen, Mandana Nikpour, Thomas Krieg, Christopher P. Denton & Amanda M. Saracino. (2022) Systemic sclerosis in adults. Part I: Clinical features and pathogenesis. Journal of the American Academy of Dermatology 87:5, pages 937-954.
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Ziying Zhu, Qian Hou, Meirong Li & Xiaobing Fu. (2019) Molecular mechanism of myofibroblast formation and strategies for clinical drugs treatments in hypertrophic scars. Journal of Cellular Physiology 235:5, pages 4109-4119.
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Swarna Bale, Gauthami Pulivendala & Chandraiah Godugu. (2018) Withaferin A attenuates bleomycin‐induced scleroderma by targeting FoxO3a and NF‐κβ signaling: Connecting fibrosis and inflammation. BioFactors 44:6, pages 507-517.
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Peter J Wermuth, Sonsoles Piera-Velazquez & Sergio A Jimenez. (2018) Identification of novel systemic sclerosis biomarkers employing aptamer proteomic analysis. Rheumatology 57:10, pages 1698-1706.
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Ramazan Rezaei, Saeed Aslani, Navid Dashti, Ahmadreza Jamshidi, Farhad Gharibdoost & Mahdi Mahmoudi. (2018) Genetic implications in the pathogenesis of systemic sclerosis. International Journal of Rheumatic Diseases 21:8, pages 1478-1486.
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Peter J. Wermuth, Sonsoles Piera-Velazquez, Joel Rosenbloom & Sergio A. Jimenez. (2018) Existing and novel biomarkers for precision medicine in systemic sclerosis. Nature Reviews Rheumatology 14:7, pages 421-432.
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Zariel I. Johnson, Jacqueline D. Jones, Angana Mukherjee, Dianxu Ren, Carol Feghali-Bostwick, Yvette P. Conley & Cecelia C. Yates. (2018) Novel classification for global gene signature model for predicting severity of systemic sclerosis. PLOS ONE 13:6, pages e0199314.
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Marie Dominique Ah Kioon, Claudio Tripodo, David Fernandez, Kyriakos A. Kirou, Robert F. SpieraMary K. Crow, Jessica K. GordonFranck J. Barrat. (2018) Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8. Science Translational Medicine 10:423.
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John Varga, Maria Trojanowska & Masataka Kuwana. (2017) Pathogenesis of systemic sclerosis: recent insights of molecular and cellular mechanisms and therapeutic opportunities. Journal of Scleroderma and Related Disorders 2:3, pages 137-152.
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A.M. Saracino, C.P. Denton & C.H. Orteu. (2017) The molecular pathogenesis of morphoea: from genetics to future treatment targets. British Journal of Dermatology 177:1, pages 34-46.
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Lizhi Cao, Robert Lafyatis & Linda C. Burkly. (2017) Increased dermal collagen bundle alignment in systemic sclerosis is associated with a cell migration signature and role of Arhgdib in directed fibroblast migration on aligned ECMs. PLOS ONE 12:6, pages e0180751.
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Monique Hinchcliff & Michael L. Whitfield. 2017. Scleroderma. Scleroderma 657 670 .
Gloria Salazar & Maureen D. Mayes. (2015) Genetics, Epigenetics, and Genomics of Systemic Sclerosis. Rheumatic Disease Clinics of North America 41:3, pages 345-366.
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Benjamin D. Korman & Lindsey A. Criswell. (2015) Recent Advances in the Genetics of Systemic Sclerosis: Toward Biological and Clinical Significance. Current Rheumatology Reports 17:3.
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Rucsandra Dobrota, Carina Mihai & Oliver Distler. (2014) Personalized Medicine in Systemic Sclerosis: Facts and Promises. Current Rheumatology Reports 16:6.
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Tracy Frech, Ivana De Domenico, Maureen A. Murtaugh, Monica P. Revelo, Dean Y. Li, Allen D. Sawitzke & Stavros Drakos. (2013) Autophagy is a key feature in the pathogenesis of systemic sclerosis. Rheumatology International 34:3, pages 435-439.
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Monique Hinchcliff, Chiang-Ching Huang, Tammara A. Wood, J. Matthew Mahoney, Viktor Martyanov, Swati Bhattacharyya, Zenshiro Tamaki, Jungwha Lee, Mary Carns, Sofia Podlusky, Arlene Sirajuddin, Sanjiv J. Shah, Rowland W. Chang, Robert Lafyatis, John Varga & Michael L. Whitfield. (2013) Molecular Signatures in Skin Associated with Clinical Improvement during Mycophenolate Treatment in Systemic Sclerosis. Journal of Investigative Dermatology 133:8, pages 1979-1989.
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Gisela E Lindahl, Carmel JW Stock, Xu Shi-Wen, Patricia Leoni, Piersante Sestini, Sarah L Howat, George Bou-Gharios, Andrew G Nicholson, Christopher P Denton, Jan C Grutters, Toby M Maher, Athol U Wells, David J Abraham & Elisabetta A Renzoni. (2013) Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease. Respiratory Research 14:1, pages 80.
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Paola Cordiali-Fei, Anna Mussi, Giovanna D'Agosto, Elisabetta Trento, Valentina Bordignon, Silvana Trincone, Antonella Vento, Isabella Sperduti, Antonio Cristaudo & Fabrizio Ensoli. (2013) Assessment of T Regulatory Cells and Expanded Profiling of Autoantibodies May Offer Novel Biomarkers for the Clinical Management of Systemic Sclerosis and Undifferentiated Connective Tissue Disease. Clinical and Developmental Immunology 2013, pages 1-7.
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Matthew B. Greenblatt & Antonios O. Aliprantis. (2012) The Immune Pathogenesis of Scleroderma: Context Is Everything. Current Rheumatology Reports 15:1.
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Boris Hinz, Sem H. Phan, Victor J. Thannickal, Marco Prunotto, Alexis Desmoulière, John Varga, Olivier De Wever, Marc Mareel & Giulio Gabbiani. (2012) Recent Developments in Myofibroblast Biology. The American Journal of Pathology 180:4, pages 1340-1355.
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