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Expert Review of Clinical Immunology Volume 8, 2012 - Issue 3
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Review

Autoimmune heart disease: role of sex hormones and autoantibodies in disease pathogenesis

DeLisa Fairweather Johns Hopkins University Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N. Wolfe Street, Baltimore, MD 21205, USA; Johns Hopkins University Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N. Wolfe Street, Baltimore, MD 21205, USA. [email protected]
,
Michelle A Petri Johns Hopkins University School of Medicine, Division of Rheumatology, 1830 East Monument Street, Baltimore, MD 21205, USA; Johns Hopkins University School of Medicine, Division of Rheumatology, 1830 East Monument Street, Baltimore, MD 21205, USA
,
Michael J Coronado Johns Hopkins University Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N. Wolfe Street, Baltimore, MD 21205, USA; Johns Hopkins University Bloomberg School of Public Health, Department of Environmental Health Sciences, 615 N. Wolfe Street, Baltimore, MD 21205, USA
&
Leslie T Cooperr Mayo Clinic, Department of Medicine, 200 First Street SW, Rochester, MN 55905, USA; Mayo Clinic, Department of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Pages 269-284 | Published online: 10 Jan 2014

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Abdullah Jameel Aburiziza. (2020) Primary Juvenile Sjögren’s Syndrome in a 3-Year-Old Pediatric Female Patient: Diagnostic Role of Salivary Gland Ultrasonography: Case Report. Open Access Rheumatology: Research and Reviews 12, pages 73-78.
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Nathan Foulquier, Pascal Redou, Christophe Le Gal, Bénédicte Rouvière, Jacques-Olivier Pers & Alain Saraux. (2018) Pathogenesis-based treatments in primary Sjogren's syndrome using artificial intelligence and advanced machine learning techniques: a systematic literature review. Human Vaccines & Immunotherapeutics 14:11, pages 2553-2558.
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Articles from other publishers (51)

Hongjun Ba, Daoqi Zhang, Shiyang Guan & Jinxin Zheng. (2023) Global burden of myocarditis and cardiomyopathy in children and prediction for 2035 based on the global burden of disease study 2019. Frontiers in Cardiovascular Medicine 10.
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Zena K. Chatila & Elizabeth M. Bradshaw. (2021) Alzheimer’s Disease Genetics: A Dampened Microglial Response?. The Neuroscientist 29:2, pages 245-263.
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Girolamo Giannotta, Antonio Murrone & Nicola Giannotta. (2023) COVID-19 mRNA Vaccines: The Molecular Basis of Some Adverse Events. Vaccines 11:4, pages 747.
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Koraljka Hat, Ana Planinić, Davor Ježek & Snježana Kaštelan. (2023) Expression of Androgen and Estrogen Receptors in the Human Lacrimal Gland. International Journal of Molecular Sciences 24:6, pages 5609.
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Emanuele Bobbio, Clara Hjalmarsson, Marie Björkenstam, Christian L. Polte, Anders Oldfors, Ulf Lindström, Pia Dahlberg, Sven-Erik Bartfay, Piotr Szamlewski, Amar Taha, Egidija Sakiniene, Kristjan Karason, Niklas Bergh & Entela Bollano. (2022) Diagnosis, management, and outcome of cardiac sarcoidosis and giant cell myocarditis: a Swedish single center experience. BMC Cardiovascular Disorders 22:1.
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Taejoon Won, Hannah M. Kalinoski, Megan K. Wood, David M. Hughes, Camille M. Jaime, Paul Delgado, Monica V. Talor, Ninaad Lasrado, Jay Reddy & Daniela Čiháková. (2022) Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis. Cell Reports 41:6, pages 111611.
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Nour Beydoun & Matthew J. Feinstein. (2022) Heart Failure in Chronic Infectious and Inflammatory Conditions: Mechanistic Insights from Clinical Heterogeneity. Current Heart Failure Reports 19:5, pages 267-278.
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Luigia Trabace, Fiorentina Roviezzo & Antonietta Rossi. (2022) Editorial: Sex Differences in Inflammatory Diseases. Frontiers in Pharmacology 13.
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Livia Silva Araújo Passos, Dakota Becker-Greene & Elena Aikawa. 2022. Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease. Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease 327 340 .
Danielle J. Beetler, Katelyn A. Bruno & DeLisa Fairweather. 2022. Translational Autoimmunity. Translational Autoimmunity 167 188 .
Samer R. KhanRobin P. PeetersPetrus Martin van HagenVirgil DalmLayal Chaker. (2021) Determinants and Clinical Implications of Thyroid Peroxidase Antibodies in Middle-Aged and Elderly Individuals: The Rotterdam Study. Thyroid.
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Aimeé Salas-Hernández, Felipe Ruz-Cortés, Francisca Bruggendieck, Claudio Espinoza-Perez, Jenaro Espitia-Corredor, Nelson M. Varela, Luis A. Quiñones, Carlos Sánchez-Ferrer, Concepción Peiró & Guillermo Díaz-Araya. (2021) Resolvin D1 reduces expression and secretion of cytokines and monocyte adhesion triggered by Angiotensin II, in rat cardiac fibroblasts. Biomedicine & Pharmacotherapy 141, pages 111947.
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Katelyn A. Bruno, Logan P. Macomb, A. Carolina Morales-Lara, Jessica E. Mathews, J. Augusto Frisancho, Alex L. Yang, Damian N. Di Florio, Brandy H. Edenfield, Emily R. Whelan, Gary R. Salomon, Anneliese R. Hill, Chathuranga C. Hewa-Rahinduwage, Ashley J. Scott, Henry D. Greyner, Frank A. Molina, Merci S. Greenaway, George M. Cooper & DeLisa Fairweather. (2021) Sex-Specific Effects of Plastic Caging in Murine Viral Myocarditis. International Journal of Molecular Sciences 22:16, pages 8834.
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Tanvirul Hye, Pankaj Dwivedi, Wei Li, Tim Lahm, Eva Nozik-Grayck, Kurt R. Stenmark & Fakhrul Ahsan. (2021) Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology 320:6, pages L1025-L1037.
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Maria Luisa Barcena, Sarah Jeuthe, Maximilian H. Niehues, Sofya Pozdniakova, Natalie Haritonow, Anja A. Kühl, Daniel R. Messroghli & Vera Regitz-Zagrosek. (2021) Sex-Specific Differences of the Inflammatory State in Experimental Autoimmune Myocarditis. Frontiers in Immunology 12.
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Angita Jain, Nadine Norton, Katelyn A. Bruno, Leslie T. CooperJr.Jr., Paldeep S. Atwal & DeLisa Fairweather. (2021) Sex Differences, Genetic and Environmental Influences on Dilated Cardiomyopathy. Journal of Clinical Medicine 10:11, pages 2289.
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Ji-Hee Nam, Jun-Ho Lee, So-Yeon Choi, Nam-Chul Jung, Jie-Young Song, Han-Geuk Seo & Dae-Seog Lim. (2021) Functional Ambivalence of Dendritic Cells: Tolerogenicity and Immunogenicity. International Journal of Molecular Sciences 22:9, pages 4430.
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Yihai Liu, Jiamin Xu, Mingyue Wu, Lina Kang & Biao Xu. (2020) The effector cells and cellular mediators of immune system involved in cardiac inflammation and fibrosis after myocardial infarction. Journal of Cellular Physiology 235:12, pages 8996-9004.
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Ninaad Lasrado & Jay Reddy. (2020) An overview of the immune mechanisms of viral myocarditis. Reviews in Medical Virology 30:6, pages 1-14.
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Neha Chanana, Tsering Palmo, Kavita Sharma, Rahul Kumar, Brian B. Graham & Qadar Pasha. (2020) Sex-derived attributes contributing to SARS-CoV-2 mortality. American Journal of Physiology-Endocrinology and Metabolism 319:3, pages E562-E567.
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Shuang Chen, Janet L. Markman, Kenichi Shimada, Timothy R. Crother, Malcolm Lane, Amanda Abolhesn, Prediman K. Shah & Moshe Arditi. (2020) Sex-Specific Effects of the Nlrp3 Inflammasome on Atherogenesis in LDL Receptor-Deficient Mice. JACC: Basic to Translational Science 5:6, pages 582-598.
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Damian N. Di Florio, Jon Sin, Michael J. Coronado, Paldeep S. Atwal & DeLisa Fairweather. (2020) Sex differences in inflammation, redox biology, mitochondria and autoimmunity. Redox Biology 31, pages 101482.
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Vera Regitz-Zagrosek, Renee Ventura-Clapier, Hester den Ruijter, Anne Garnier, Maria Louisa Barcena, Anouk Eikendal & Robin Hartman. 2019. Sex Differences in Cardiovascular Physiology and Pathophysiology. Sex Differences in Cardiovascular Physiology and Pathophysiology 291 318 .
Kyle A. Batton, Christopher O. Austin, Katelyn A. Bruno, Charles D. Burger, Brian P. Shapiro & DeLisa Fairweather. (2018) Sex differences in pulmonary arterial hypertension: role of infection and autoimmunity in the pathogenesis of disease. Biology of Sex Differences 9:1.
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Aisha Siraj, Rimsha Hasan & Sabha Bhatti. 2018. Gender Differences in the Pathogenesis and Management of Heart Disease. Gender Differences in the Pathogenesis and Management of Heart Disease 63 77 .
Nirav R. Shah, Braxton D. Noll, Craig B. Stevens, Michael T. Brennan, Farah B. Mougeot & Jean-Luc C. Mougeot. (2017) Biosemantics guided gene expression profiling of Sjögren’s syndrome: a comparative analysis with systemic lupus erythematosus and rheumatoid arthritis. Arthritis Research & Therapy 19:1.
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Andreas Koenig, Iwona Buskiewicz & Sally A. Huber. (2017) Age-Associated Changes in Estrogen Receptor Ratios Correlate with Increased Female Susceptibility to Coxsackievirus B3-Induced Myocarditis. Frontiers in Immunology 8.
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Leslie T. CooperJr.Jr.. (2017) The Changing Face of Cardiac Inflammation. Circulation: Heart Failure 10:11.
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Jo-Ann Eastwood, Doris A. Taylor, B. Delia Johnson, Micheline Resende, Barry L. Sharaf, Bina Ahmed, Margo Minissian, Chrisandra Shufelt & Noel Bairey Merz. (2017) Premature atherosclerosis in premenopausal women: Does cytokine balance play a role?. Medical Hypotheses 109, pages 38-41.
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Austin C. BoeseSeong C. KimKe-Jie YinJean-Pyo Lee & Milton H. Hamblin. (2017) Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease. American Journal of Physiology-Heart and Circulatory Physiology 313:3, pages H524-H545.
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Amos Tambo, Mohsin H.K. Roshan & Nikolai P. Pace. (2016) Testosterone and Cardiovascular Disease. The Open Cardiovascular Medicine Journal 10:1, pages 1-10.
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Jessica E. Brandt, Roberta Priori, Guido Valesini & DeLisa Fairweather. (2015) Sex differences in Sjögren’s syndrome: a comprehensive review of immune mechanisms. Biology of Sex Differences 6:1.
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DeLisa Fairweather & Robert Root‐Bernstein. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 7 .
Robert Root-Bernstein & DeLisa Fairweather. (2015) Unresolved issues in theories of autoimmune disease using myocarditis as a framework. Journal of Theoretical Biology 375, pages 101-123.
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Jeffrey A. Shih & Jennifer A. Shih. (2015) Small Steps for Idiopathic Giant Cell Myocarditis. Current Heart Failure Reports 12:3, pages 263-268.
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Aoife O’Donovan, Beth E. Cohen, Karen H. Seal, Dan Bertenthal, Mary Margaretten, Kristen Nishimi & Thomas C. Neylan. (2015) Elevated Risk for Autoimmune Disorders in Iraq and Afghanistan Veterans with Posttraumatic Stress Disorder. Biological Psychiatry 77:4, pages 365-374.
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DeLisa Fairweather. 2015. Skin, Mucosa and Menopause. Skin, Mucosa and Menopause 359 381 .
Willem J. Kop & Paula M. C. Mommersteeg. 2015. Psychosocial Stress and Cardiovascular Disease in Women. Psychosocial Stress and Cardiovascular Disease in Women 129 149 .
Alessia Veia, Chiara Cavallino, Sara Bacchini, Fabio Pastore, Alessandro Lupi, Andrea Rognoni, Francesco Rametta & Angelo Sante Bongo. (2014) Idiopathic Giant Cell Myocarditis: State of the Art. World Journal of Cardiovascular Diseases 04:06, pages 316-324.
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Delisa Fairweather. (2015) Sex Differences in Inflammation during Atherosclerosis. Clinical Medicine Insights: Cardiology 8s3, pages CMC.S17068.
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Hatice Duygu BasKazim BaserEmine YavuzHasan Ata BolayirBelma YamanSerkan UnluAtiye CengelEmin Umit BagriacikRidvan Yalcin. (2023) A Shift in the Balance of Regulatory T and T Helper 17 Cells in Rheumatic Heart Disease. Journal of Investigative Medicine 62:1, pages 78-83.
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Robert Root-Bernstein & DeLisa Fairweather. (2013) Complexities in the Relationship Between Infection and Autoimmunity. Current Allergy and Asthma Reports 14:1.
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Lori A. Blauwet & Leslie T. Cooper. (2012) Idiopathic giant cell myocarditis and cardiac sarcoidosis. Heart Failure Reviews 18:6, pages 733-746.
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Jay Reddy, Chandirasegaran Massilamany, Iwona Buskiewicz & Sally A. Huber. (2013) Autoimmunity in viral myocarditis. Current Opinion in Rheumatology 25:4, pages 502-508.
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DeLisa Fairweather, Leslie T. CooperJrJr & Lori A. Blauwet. (2013) Sex and Gender Differences in Myocarditis and Dilated Cardiomyopathy. Current Problems in Cardiology 38:1, pages 7-46.
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Taejoon Won, Hannah M. Kalinoski, Megan K. Wood, David M. Hughes, Camille M. Jaime, Monica Talor, Ninaad Lasrado, Jay Reddy & Daniela Cihakova. (2022) Cardiac Myosin-Specific Autoimmune T Cells Contribute to Immune Checkpoint Inhibitor-Associated Myocarditis. SSRN Electronic Journal.
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