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Review

Current status of monoclonal antibody therapy for the treatment of inflammatory bowel disease: an update

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Pages 77-92 | Published online: 10 Jan 2014

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Christian L. Hvas, Mia Bendix, Anders Dige, Jens F. Dahlerup & Jørgen Agnholt. (2018) Current, experimental, and future treatments in inflammatory bowel disease: a clinical review. Immunopharmacology and Immunotoxicology 40:6, pages 446-460.
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Anders Dige, Maria K. Magnusson, Lena Öhman, Christian Lodberg Hvas, Jens Kelsen, Mary Jo Wick & Jørgen Agnholt. (2016) Reduced numbers of mucosal DRint macrophages and increased numbers of CD103+ dendritic cells during anti-TNF-α treatment in patients with Crohn’s disease. Scandinavian Journal of Gastroenterology 51:6, pages 692-699.
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Luiz C Di Stasi, Celso ARA Costa & Aline Witaicenis. (2015) Products for the treatment of inflammatory bowel disease: a patent review (2013 – 2014). Expert Opinion on Therapeutic Patents 25:6, pages 629-642.
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Aristeidis H Katsanos & Konstantinos H Katsanos. (2014) Inflammatory bowel disease and demyelination: more than just a coincidence?. Expert Review of Clinical Immunology 10:3, pages 363-373.
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Articles from other publishers (21)

Hsuan Ping Chang, Valentina Shakhnovich, Adam Frymoyer, Ryan Sol Funk, Mara L. Becker, K. T. Park & Dhaval K. Shah. (2021) A population physiologically‐based pharmacokinetic model to characterize antibody disposition in pediatrics and evaluation of the model using infliximab. British Journal of Clinical Pharmacology 88:1, pages 290-302.
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Tingyue Tu, Mao Yu, Yanping Zhang, Xiafei Shi, Jinhao Xu, Junqing Hu, Jingjing Gan, Wei He, Lei Dong, Jianlin Han, Zhen Huang, Yi Pan & Junfeng Zhang. (2018) A novel fluorinated triazole derivative suppresses macrophage activation and alleviates experimental colitis via a Twist1-dependent pathway. Biochemical Pharmacology 155, pages 275-287.
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Oscar Hernandez-Alba, Elsa Wagner-Rousset, Alain Beck & Sarah Cianférani. (2018) Native Mass Spectrometry, Ion Mobility, and Collision-Induced Unfolding for Conformational Characterization of IgG4 Monoclonal Antibodies. Analytical Chemistry 90:15, pages 8865-8872.
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M. Jack Borrok, Antonio DiGiandomenico, Nurten Beyaz, Gabriela M. Marchetti, Arnita S. Barnes, Kristen J. Lekstrom, Sandrina S. Phipps, Michael P. McCarthy, Herren Wu, William F. Dall’Acqua, Ping Tsui & Ruchi Gupta. (2018) Enhancing IgG distribution to lung mucosal tissue improves protective effect of anti–Pseudomonas aeruginosa antibodies. JCI Insight 3:12.
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Jesús K. Yamamoto-Furusho & Andrea Sarmiento-Aguilar. (2017) Joint involvement in Mexican patients with ulcerative colitis: a hospital-based retrospective study. Clinical Rheumatology 37:3, pages 677-682.
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Anders Dige, Maria K. Magnusson, Claus Uhrenholt, Tue Kruse Rasmussen, Tue Kragstrup, Lena Öhman, Jens Dahlerup & Jørgen Agnholt. (2018) Effects of Anti-TNF α Treatment on Mucosal Expression of IL-17A, IL-21, and IL-22 and Cytokine-Producing T Cell Subsets in Crohn’s Disease . Mediators of Inflammation 2018, pages 1-7.
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Tianshu Xu, Tianlei Ying, Lili Wang, Xiaohua Douglas Zhang, Ying Wang, Lishan Kang, Tao Huang, Liang Cheng, Liping Wang & Qi Zhao. (2017) A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A. Oncotarget 8:47, pages 81860-81872.
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Xing Yu Jin, Dong Hwan Sohn & Sung Hee Lee. (2016) Isoliquiritigenin suppresses tumor necrosis factor-α-induced inflammation via peroxisome proliferator-activated receptor-γ in intestinal epithelial cells. Archives of Pharmacal Research 39:10, pages 1465-1471.
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Tae Kang & Hyun Kim. (2016) Farewell to Animal Testing: Innovations on Human Intestinal Microphysiological Systems. Micromachines 7:7, pages 107.
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B Gurram, N H Salzman, M L Kaldunski, S Jia, B U K Li, M Stephens, M R Sood & M J Hessner. (2016) Plasma-induced signatures reveal an extracellular milieu possessing an immunoregulatory bias in treatment-naive paediatric inflammatory bowel disease. Clinical and Experimental Immunology 184:1, pages 36-49.
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Vijay Rajeshwarrao Chidrawar. (2016) Exploiting the role of various types of ion-channels against chemically induced inflammatory bowel disease in male Wistar rats. Asian Pacific Journal of Tropical Disease 6:2, pages 90-99.
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Francesco Caso, Luisa Costa, Antonio Del Puente, Matteo Nicola Dario Di Minno, Gelsy Lupoli, Raffaele Scarpa & Rosario Peluso. (2015) Pharmacological treatment of spondyloarthritis: exploring the effectiveness of nonsteroidal anti-inflammatory drugs, traditional disease-modifying antirheumatic drugs and biological therapies. Therapeutic Advances in Chronic Disease 6:6, pages 328-338.
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Laith Alrubaiy, Ibtihal Rikaby, Mohamed Sageer, Hayley Anne Hutchings & John Gordon Williams. (2015) Systematic Review of the Clinical Disease Severity Indices for Inflammatory Bowel Disease. Inflammatory Bowel Diseases, pages 1.
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Raquel Franco Leal, Núria Planell, Radhika Kajekar, Juan J Lozano, Ingrid Ordás, Isabella Dotti, Miriam Esteller, M Carme Masamunt, Harsukh Parmar, Elena Ricart, Julián Panés & Azucena Salas. (2015) Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy. Gut 64:2, pages 233-242.
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A. Dige, S. Støy, K. L. Thomsen, C. L. Hvas, J. Agnholt, J. F. Dahlerup, H. J. Møller & H. Grønbaek. (2014) Soluble CD163, a Specific Macrophage Activation Marker, is Decreased by Anti-TNF- α Antibody Treatment in Active Inflammatory Bowel Disease . Scandinavian Journal of Immunology 80:6, pages 417-423.
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Mark D. Turner, Belinda Nedjai, Tara Hurst & Daniel J. Pennington. (2014) Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:11, pages 2563-2582.
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Vincenzo Bruner, Mariangela Atteno, Angelo Spanò, Raffaele Scarpa & Rosario Peluso. (2014) Biological therapies for spondyloarthritis. Therapeutic Advances in Musculoskeletal Disease 6:3, pages 92-101.
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K. T. Park, Wallace V. Crandall, Jacqueline Fridge, Ian H. Leibowitz, Marc Tsou, Dana M. H. Dykes, Edward J. Hoffenberg, Michael D. Kappelman & Richard B. Colletti. (2014) Implementable Strategies and Exploratory Considerations to Reduce Costs Associated with Anti-TNF Therapy in Inflammatory Bowel Disease. Inflammatory Bowel Diseases 20:5, pages 946-951.
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Fabiola Atzeni, Caterina Defendenti, Maria Chiara Ditto, Alberto Batticciotto, Donatella Ventura, Marco Antivalle, Sandro Ardizzone & Piercarlo Sarzi-Puttini. (2014) Rheumatic manifestations in inflammatory bowel disease. Autoimmunity Reviews 13:1, pages 20-23.
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Jeannie K. Lee, Derek H. Tang, Lea Mollon & Edward P. Armstrong. (2013) Cost-effectiveness of biological agents used in ulcerative colitis. Best Practice & Research Clinical Gastroenterology 27:6, pages 949-960.
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K. B. Lankarani. (2013) Letter: rapid infliximab infusion is not always safe. Alimentary Pharmacology & Therapeutics 38:7, pages 844-844.
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