2,435
Views
51
CrossRef citations to date
0
Altmetric
Review

Reduced-intensity conditioning for allogeneic stem cell transplant in primary immune deficiencies

&
Pages 255-267 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Claire Booth, Juliana Silva & Paul Veys. (2016) Stem cell transplantation for the treatment of immunodeficiency in children: current status and hopes for the future. Expert Review of Clinical Immunology 12:7, pages 713-723.
Read now
Austen JJ Worth & Adrian J Thrasher. (2015) Current and emerging treatment options for Wiskott–Aldrich syndrome. Expert Review of Clinical Immunology 11:9, pages 1015-1032.
Read now

Articles from other publishers (49)

Gizem Zengin Ersoy, Funda Çipe, Tunç Fışgın, Basak Adakli Aksoy, Özlem Başoğlu Öner, Nazlı Hashemi, Selime Aydoğdu, Melek Erdem, Gürcan Dikme, Koza Murat & Ceyhun Bozkurt. (2023) The impact of Treosulfan‐based conditioning for inborn errors of immunity: Is dose monitoring crucial?. Clinical Transplantation.
Crossref
Michael Sugiyanto, Stephanie Gosal, Agatha Kosim, Dicky Levenus Tahapary & Imelda Rosalyn Sianipar. (2023) Impact of the source of hematopoietic stem cells on immune reconstitution after transplantation: A systematic review. European Journal of Haematology 111:1, pages 4-14.
Crossref
Sara Zulu & Michelle Kenyon. 2023. The European Blood and Marrow Transplantation Textbook for Nurses. The European Blood and Marrow Transplantation Textbook for Nurses 91 99 .
Katsutsugu Umeda. (2022) Unresolved issues in allogeneic hematopoietic cell transplantation for non-malignant diseases. International Journal of Hematology 116:1, pages 41-47.
Crossref
Mohammad Vaezi, Maryam Souri, Seyed Amin Setarehdan, Amir Ali Hamidieh, Mohammad Reza Fazlollahi, Zahra Pourpak, Mohsen Badalzadeh, Shaghayegh Tajik, Seyed Alireza Mahdaviani, Kamran Alimoghaddam & Ardeshir Ghavamzadeh. (2022) A fludarabine and melphalan reduced-intensity conditioning regimen for HSCT in fifteen chronic granulomatous disease patients and a literature review. Annals of Hematology 101:4, pages 869-880.
Crossref
Gabriela Llaurador, Eileen Nicoletti, Susan E. Prockop, Susan Hsu, Kirsten Fuller, Audrey Mauguen, Richard J. O'Reilly, Jaap J. Boelens & Farid Boulad. (2021) Donor-Host Lineage-Specific Chimerism Monitoring and Analysis in Pediatric Patients Following Allogeneic Stem Cell Transplantation: Influence of Pretransplantation Variables and Correlation with Post-Transplantation Outcomes. Transplantation and Cellular Therapy 27:9, pages 780.e1-780.e14.
Crossref
Tahani Ali, Maryam Behfar, Rashin Mohseni, Pourya Salajegheh, Maged Kheder, Faihaa Abou-Fakher, Zeynab Nikfetrat, Fahimeh Jafari, Parisa Naji & Amir Ali Hamidieh. (2021) Escalated dose donor lymphocyte infusion treatment in patients with primary immune deficiencies after HSCT with reduced-intensity conditioning regimen. Hematology/Oncology and Stem Cell Therapy.
Crossref
Xiangfeng Tang, Zhang Yu, Liu Ping, Wei Lu, Yuanfang Jing & Xiuyan Cao. (2021) Improved outcomes using unmanipulated haploidentical hematopoietic stem cells combined with third‐party umbilical cord blood transplantation for non‐malignant diseases in children: The experience of a single center. Pediatric Transplantation 25:4.
Crossref
Nicolaas G. van der Maas, Erik G. J. von Asmuth, Dagmar Berghuis, Pauline A. van Schouwenburg, Hein Putter, Mirjam van der Burg & Arjan C. Lankester. (2021) Modeling Influencing Factors in B-Cell Reconstitution After Hematopoietic Stem Cell Transplantation in Children. Frontiers in Immunology 12.
Crossref
Maged Kheder, Maryam Behfar, Hamid Farajifard, Tahani Ali, Faihaa Hkima Abou Fakher & Amir Ali Hamidieh. (2020) Fludarabine‐based reduced‐intensity conditioning regimen for hematopoietic stem cell transplantation in pediatric patient with IL10 receptor deficiency. Pediatric Transplantation 25:2.
Crossref
Megan A. Cooper, Ofer Zimmerman, Ramya Nataraj & Robert F. Wynn. (2021) Lifelong Immune Modulation Versus Hematopoietic Cell Therapy for Inborn Errors of Immunity. The Journal of Allergy and Clinical Immunology: In Practice 9:2, pages 628-639.
Crossref
Sharat Chandra, Shanmuganathan Chandrakasan, Blachy J. Dávila Saldaña, Jack J. Bleesing, Michael B. Jordan, Ashish R. Kumar, Michael S. Grimley, Christa Krupski, Stella M. Davies, Pooja Khandelwal & Rebecca A. Marsh. (2020) Experience with a Reduced Toxicity Allogeneic Transplant Regimen for Non-CGD Primary Immune Deficiencies Requiring Myeloablation. Journal of Clinical Immunology 41:1, pages 89-98.
Crossref
Manuela Olaya, Alexis Franco, Mauricio Chaparro, Marcela Estupiñan, David Aristizabal, Natalia Builes-Restrepo, José L Franco, Andrés F Zea-Vera, Mayra Estacio, Eliana Manzi, Estefania Beltran, Paola Perez, Jaime Patiño, Harry Pachajoa & Diego Medina-Valencia. (2020) Hematopoietic Stem Cell Transplantation in Children with Inborn Errors of Immunity: a Multi-center Experience in Colombia. Journal of Clinical Immunology 40:8, pages 1116-1123.
Crossref
Alison Leiper, Maite Houwing, E. Graham Davies, Kanchan Rao, Siobhan Burns, Emma Morris, Joop Laven, Anne-Lotte van der Kooi, Marry van den Heuvel Eibrink & Stephen Nussey. (2020) Anti-Müllerian hormone and Inhibin B after stem cell transplant in childhood: a comparison of myeloablative, reduced intensity and treosulfan-based chemotherapy regimens. Bone Marrow Transplantation 55:10, pages 1985-1995.
Crossref
Robert Chiesa, Joseph F. Standing, Robert Winter, Zohreh Nademi, Jan Chu, Danielle Pinner, Frank Kloprogge, Susan McLellen, Persis J. Amrolia, Kanchan Rao, Giovanna Lucchini, Juliana Silva, Oana Ciocarlie, Arina Lazareva, Andrew R. Gennery, Bilyana Doncheva, Andrew J. Cant, Sophie Hambleton, Terence Flood, Elizabeth Rogerson, Kirsty Devine, Helen Prunty, Simon Heales, Paul Veys & Mary Slatter. (2019) Proposed Therapeutic Range of Treosulfan in Reduced Toxicity Pediatric Allogeneic Hematopoietic Stem Cell Transplant Conditioning: Results From a Prospective Trial. Clinical Pharmacology & Therapeutics 108:2, pages 264-273.
Crossref
Katsutsugu Umeda, Kohsuke Imai, Masakatsu Yanagimachi, Hiromasa Yabe, Masao Kobayashi, Yoshiyuki Takahashi, Michiko Kajiwara, Nao Yoshida, Yuko Cho, Masami Inoue, Yoshiko Hashii, Yoshiko Atsuta & Tomohiro Morio. (2020) Impact of graft-versus-host disease on the clinical outcome of allogeneic hematopoietic stem cell transplantation for non-malignant diseases. International Journal of Hematology 111:6, pages 869-876.
Crossref
Ehud Even‐Or, Shahar Altman Kohl, Irina Zaidman, Polina Stepensky & Vered Molho‐Pessach. (2019) Skin toxicity following treosulfan‐thiotepa‐fludarabine‐based conditioning regimen in non‐malignant pediatric patients undergoing hematopoietic stem cell transplantation. Pediatric Transplantation 24:1.
Crossref
Beatriz Morillo-Gutierrez & Mary Slatter. 2020. Pediatric Autoimmunity and Transplantation. Pediatric Autoimmunity and Transplantation 229 236 .
Vipin Khandelwal, Sanjeev Kumar Sharma, Divya Doval, Meet Kumar & Dharma Choudhary. (2019) Haploidentical stem cell transplantation with post-transplant cyclophosphamide in leukocyte adhesion deficiency type 1: a case report. Annals of Hematology 98:10, pages 2425-2426.
Crossref
Katsutsugu Umeda, Hiromasa Yabe, Koji Kato, Kohsuke Imai, Masao Kobayashi, Yoshiyuki Takahashi, Nao Yoshida, Maho Sato, Yoji Sasahara, Keisuke Kato, Souichi Adachi, Yuhki Koga, Keiko Okada, Masami Inoue, Yoshiko Hashii, Yoshiko Atsuta & Tomohiro Morio. (2018) Impact of low-dose irradiation and in vivo T-cell depletion on hematopoietic stem cell transplantation for non-malignant diseases using fludarabine-based reduced-intensity conditioning. Bone Marrow Transplantation 54:8, pages 1227-1236.
Crossref
Nicolaas G. van der Maas, Dagmar Berghuis, Mirjam van der Burg & Arjan C. Lankester. (2019) B Cell Reconstitution and Influencing Factors After Hematopoietic Stem Cell Transplantation in Children. Frontiers in Immunology 10.
Crossref
Karlie Jones, Sarah Bryant, Jian Luo, Patricia Kiesler, Sherry Koontz, James Warren, Harry Malech, Elizabeth Kang & Gabriela Dveksler. (2019) Recombinant Pregnancy-Specific Glycoprotein 1 Has a Protective Role in a Murine Model of Acute Graft-versus-Host Disease. Biology of Blood and Marrow Transplantation 25:2, pages 193-203.
Crossref
Chaim M. Roifman. 2019. Clinical Immunology. Clinical Immunology 489 508.e1 .
Şule Haskoloğlu, Sevgi Köstel Bal, Candan İslamoğlu, Demet Altun, Tanıl Kendirli, Esin Figen Doğu & Aydan İkincioğulları. (2018) Outcome of treosulfan-based reduced-toxicity conditioning regimens for HSCT in high-risk patients with primary immune deficiencies. Pediatric Transplantation 22:7, pages e13266.
Crossref
V. A. Lavrinenko, Y. E. Marejco, E. Y. Berezovskaya, M. V. Stegantseva, N. V. Minakowskaja & M. V. Belevtsev. (2018) DONOR CHIMERISM IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY AFTER ALLOGENEIC HEMATOPOIETIC STEM CELLS TRANSPLANTATION. Oncohematology 13:2, pages 82-92.
Crossref
Kaiyue Peng, Xiaowen Qian, Zhiheng Huang, Junping Lu, Yuhuan Wang, Ying Zhou, Huijun Wang, Bingbing Wu, Ying Wang, Lingli Chen, Xiaowen Zhai & Ying Huang. (2018) Umbilical Cord Blood Transplantation Corrects Very Early-Onset Inflammatory Bowel Disease in Chinese Patients With IL10RA-Associated Immune Deficiency. Inflammatory Bowel Diseases 24:7, pages 1416-1427.
Crossref
Lucía López-Granados, Montserrat Torrent, Ana Sastre, Marta Gonzalez-Vicent, Cristina Díaz de Heredia, Bienvenida Argilés, Antonia Pascual, José M. Pérez-Hurtado, Luisa Sisinni, Miguel Ángel Diaz, Izaskun Elorza, M. Angeles Dasí & Isabel Badell. (2018) Trasplante de progenitores hematopoyéticos con intensidad reducida en enfermedades genéticas. Experiencia del grupo GETMON (Grupo Español de Trasplante de Médula Ósea en Niños). Anales de Pediatría 88:4, pages 196-203.
Crossref
Lucía López-Granados, Montserrat Torrent, Ana Sastre, Marta Gonzalez-Vicent, Cristina Díaz de Heredia, Bienvenida Argilés, Antonia Pascual, José M. Pérez-Hurtado, Luisa Sisinni, Miguel Ángel Diaz, Izaskun Elorza, M. Angeles Dasí & Isabel Badell. (2018) Reduced-intensity conditioning haematopoietic stem cell transplantation in genetic diseases: Experience of the Spanish Working Group for Bone Marrow Transplantation in Children. Anales de Pediatría (English Edition) 88:4, pages 196-203.
Crossref
Mary A. Slatter, Kanchan Rao, Intan Juliana Abd Hamid, Zohreh Nademi, Robert Chiesa, Reem Elfeky, Mark S. Pearce, Persis Amrolia, Austen Worth, Terence Flood, Mario Abinun, Sophie Hambleton, Waseem Qasim, Hubert B. Gaspar, Andrew J. Cant, Andrew R. Gennery & Paul Veys. (2018) Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience. Biology of Blood and Marrow Transplantation 24:3, pages 529-536.
Crossref
Juliana Silva, Claire Booth & Paul Veys. 2018. Management of Infections in the Immunocompromised Host. Management of Infections in the Immunocompromised Host 375 393 .
Sara Zulu & Michelle Kenyon. 2018. The European Blood and Marrow Transplantation Textbook for Nurses. The European Blood and Marrow Transplantation Textbook for Nurses 89 96 .
Neha Rastogi, Satyendra Katewa, Dhwanee Thakkar, Shruti Kohli, Sagar Nivargi & Satya Prakash Yadav. (2018) Reduced-toxicity alternate-donor stem cell transplantation with posttransplant cyclophosphamide for primary immunodeficiency disorders. Pediatric Blood & Cancer 65:1, pages e26783.
Crossref
Masayuki Nagasawa, Teppei Ohkawa, Masatoshi Takagi, Kohsuke Imai & Tomohiro Morio. (2017) A Stable Mixed Chimera After SCT with RIC in an Infant with IκBα Hypermorphic Mutation. Journal of Clinical Immunology 37:5, pages 413-414.
Crossref
Katsutsugu Umeda, Souichi Adachi, Shiro Tanaka, Mizuka Miki, Keiko Okada, Yoshiko Hashii, Masami Inoue, Yuko Cho, Katsuyoshi Koh, Hiroaki Goto, Ryosuke Kajiwara, Nobuyuki Hyakuna, Koji Kato, Tomohiro Morio & Hiromasa Yabe. (2016) Comparison of second transplantation and donor lymphocyte infusion for donor mixed chimerism after allogeneic stem cell transplantation for nonmalignant diseases. Pediatric Blood & Cancer 63:12, pages 2221-2229.
Crossref
Rebecca H. Buckley. (2016) Progress toward less toxic conditioning. Blood 128:3, pages 322-323.
Crossref
Beatriz Morillo-GutierrezRita BeierKanchan RaoLauri BurroughsAnsgar SchulzAnna-Maria EwinsBrenda GibsonPetr SedlacekLadislav KrolBrigitte StrahmIrina ZaidmanKrzysztof KalwakJulie-An TalanoAnn WoolfreyChris FraserIsabelle MeytsIngo MüllerJacek WachowiakMaria Ester Bernardo, Paul VeysKarl-Walter SykoraAndrew R. Gennery & Mary Slatter. (2016) Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicenter experience. Blood 128:3, pages 440-448.
Crossref
A A Hamidieh, M Behfar, Z Pourpak, S Faghihi-Kashani, M R Fazlollahi, A S Hosseini, M Movahedi, M Mozafari, M Moin & A Ghavamzadeh. (2015) Long-term outcomes of fludarabine, melphalan and antithymocyte globulin as reduced-intensity conditioning regimen for allogeneic hematopoietic stem cell transplantation in children with primary immunodeficiency disorders: a prospective single center study. Bone Marrow Transplantation 51:2, pages 219-226.
Crossref
M. Julia & B. Felippe. 2016. Equine Clinical Immunology. Equine Clinical Immunology 311 316 .
Adi Ovadia & Chaim M. Roifman. 2016. Encyclopedia of Immunobiology. Encyclopedia of Immunobiology 513 521 .
Polina Y. Stepensky, Baruch Wolach, Ronit Gavrieli, Sharon Rousso, Tal Ben Ami, Vladimir Goldman, Katya Rozovsky, Suhair Hanna, Amos Etzioni & Michael Weintraub. (2015) Leukocyte Adhesion Deficiency Type III. Journal of Pediatric Hematology/Oncology 37:4, pages 264-268.
Crossref
Fatih Celmeli, Doga Turkkahraman, Vedat Uygun, Giancarlo la Marca, Michael Hershfield & Akif Yesilipek. (2015) A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency. Pediatric Transplantation 19:2, pages E47-E50.
Crossref
Paulo Vítor Soeiro-Pereira, Angela Falcai, Christina Arslanian Kubo, Edson Antunes & Antonio Condino-Neto. (2015) BAY 41-2272 activates host defence against local and disseminated Candida albicans infections. Memórias do Instituto Oswaldo Cruz 110:1, pages 75-85.
Crossref
Jesse D. Vrecenak, Erik G. Pearson, Matthew T. Santore, Carlyn A. Todorow, Haiying Li, Antoneta Radu, Tricia Bhatti, William H. Peranteau, Mark P. Johnson & Alan W. Flake. (2014) Stable long-term mixed chimerism achieved in a canine model of allogeneic in utero hematopoietic cell transplantation. Blood 124:12, pages 1987-1995.
Crossref
Amir Ali Hamidieh, Zahra Pourpak, Susan Hashemi, Kolsoum Yari, Mohammad Reza Fazlollahi, Masoud Movahedi, Maryam Behfar, Mostafa Moin & Ardeshir Ghavamzadeh. (2014) Fludarabine-based reduced-intensity conditioning regimen for hematopoietic stem cell transplantation in primary hemophagocytic lymphohistiocytosis. European Journal of Haematology 92:4, pages 331-336.
Crossref
Oded Shamriz, Shoshana Revel Vilk, Dana G. Wolf, Asaf Ta-Shma, Diana Averbuch, Michael Weintraub & Polina Stepensky. (2014) Hematopoietic stem cell transplantation conditioning with use of rituximab in EBV related lymphoproliferative disorders. Clinical Immunology 151:2, pages 79-83.
Crossref
Linda M. Griffith, Morton J. Cowan, Luigi D. Notarangelo, Donald B. Kohn, Jennifer M. Puck, Sung-Yun Pai, Barbara Ballard, Sarah C. Bauer, Jack J.H. Bleesing, Marcia Boyle, Amy Brower, Rebecca H. Buckley, Mirjam van der Burg, Lauri M. Burroughs, Fabio Candotti, Andrew J. Cant, Talal Chatila, Charlotte Cunningham-Rundles, Mary C. Dinauer, Christopher C. Dvorak, Alexandra H. Filipovich, Thomas A. Fleisher, Hubert Bobby Gaspar, Tayfun Gungor, Elie Haddad, Emily Hovermale, Faith Huang, Alan Hurley, Mary Hurley, Sumathi Iyengar, Elizabeth M. Kang, Brent R. Logan, Janel R. Long-Boyle, Harry L. Malech, Sean A. McGhee, Fred Modell, Vicki Modell, Hans D. Ochs, Richard J. O'Reilly, Robertson Parkman, David J. Rawlings, John M. Routes, William T. Shearer, Trudy N. Small, Heather Smith, Kathleen E. Sullivan, Paul Szabolcs, Adrian Thrasher, Troy R. Torgerson, Paul Veys, Kenneth Weinberg & Juan Carlos Zuniga-Pflucker. (2014) Primary Immune Deficiency Treatment Consortium (PIDTC) report. Journal of Allergy and Clinical Immunology 133:2, pages 335-347.e11.
Crossref
C. Garrido Colino. (2014) Avances en el conocimiento y manejo del síndrome linfoproliferativo autoinmune. Anales de Pediatría 80:2, pages 122.e1-122.e7.
Crossref
Michael Albert & Monika Führer. 2014. Therapie der Krankheiten im Kindes- und Jugendalter. Therapie der Krankheiten im Kindes- und Jugendalter 1461 1466 .
Jia-Hua Ding, Lin-Lin Wang, Zhi Chen, Jun Wang, Zheng-Ping Yu, Gang Zhao & Bao-An Chen. (2013) The role of Tα1 on the infective patients after hematopoietic stem cell transplantation. International Journal of Hematology 97:2, pages 280-283.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.